PMC:7647877 / 14277-14575 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T229","span":{"begin":53,"end":58},"obj":"Body_part"},{"id":"T230","span":{"begin":60,"end":62},"obj":"Body_part"},{"id":"T231","span":{"begin":76,"end":81},"obj":"Body_part"},{"id":"T232","span":{"begin":83,"end":85},"obj":"Body_part"},{"id":"T233","span":{"begin":114,"end":122},"obj":"Body_part"},{"id":"T234","span":{"begin":131,"end":135},"obj":"Body_part"},{"id":"T235","span":{"begin":131,"end":133},"obj":"Body_part"},{"id":"T236","span":{"begin":162,"end":167},"obj":"Body_part"},{"id":"T237","span":{"begin":242,"end":267},"obj":"Body_part"},{"id":"T238","span":{"begin":262,"end":267},"obj":"Body_part"},{"id":"T239","span":{"begin":286,"end":297},"obj":"Body_part"}],"attributes":[{"id":"A229","pred":"fma_id","subj":"T229","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A230","pred":"fma_id","subj":"T230","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A231","pred":"fma_id","subj":"T231","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A232","pred":"fma_id","subj":"T232","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A233","pred":"fma_id","subj":"T233","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A234","pred":"fma_id","subj":"T234","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A235","pred":"fma_id","subj":"T235","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A236","pred":"fma_id","subj":"T236","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A237","pred":"fma_id","subj":"T237","obj":"http://purl.org/sig/ont/fma/fma62499"},{"id":"A238","pred":"fma_id","subj":"T238","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A239","pred":"fma_id","subj":"T239","obj":"http://purl.org/sig/ont/fma/fma63877"}],"text":"In COVID-19 the homeostatic equilibrium between TREG cells (IL-10) and Th17 cells (IL-17) is broken: inflammatory cytokine levels (IL-1, TNF) are elevated in the lungs of COVID-19 patients, resulting in an increase in HA-synthase-2 (HAS2) in alveolar epithelial cells CD31+, EpCAM+ and fibroblasts."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T82","span":{"begin":3,"end":11},"obj":"Disease"},{"id":"T83","span":{"begin":171,"end":179},"obj":"Disease"}],"attributes":[{"id":"A82","pred":"mondo_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In COVID-19 the homeostatic equilibrium between TREG cells (IL-10) and Th17 cells (IL-17) is broken: inflammatory cytokine levels (IL-1, TNF) are elevated in the lungs of COVID-19 patients, resulting in an increase in HA-synthase-2 (HAS2) in alveolar epithelial cells CD31+, EpCAM+ and fibroblasts."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T237","span":{"begin":48,"end":52},"obj":"http://purl.obolibrary.org/obo/CL_0000792"},{"id":"T238","span":{"begin":53,"end":58},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T239","span":{"begin":76,"end":81},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T240","span":{"begin":162,"end":167},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T241","span":{"begin":251,"end":261},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T242","span":{"begin":262,"end":267},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T243","span":{"begin":268,"end":272},"obj":"http://purl.obolibrary.org/obo/CLO_0053435"},{"id":"T244","span":{"begin":286,"end":297},"obj":"http://purl.obolibrary.org/obo/CL_0000057"}],"text":"In COVID-19 the homeostatic equilibrium between TREG cells (IL-10) and Th17 cells (IL-17) is broken: inflammatory cytokine levels (IL-1, TNF) are elevated in the lungs of COVID-19 patients, resulting in an increase in HA-synthase-2 (HAS2) in alveolar epithelial cells CD31+, EpCAM+ and fibroblasts."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T157","span":{"begin":60,"end":62},"obj":"Chemical"},{"id":"T159","span":{"begin":83,"end":85},"obj":"Chemical"},{"id":"T161","span":{"begin":131,"end":133},"obj":"Chemical"},{"id":"T163","span":{"begin":218,"end":220},"obj":"Chemical"}],"attributes":[{"id":"A157","pred":"chebi_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A158","pred":"chebi_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A159","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A160","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A161","pred":"chebi_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A162","pred":"chebi_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A163","pred":"chebi_id","subj":"T163","obj":"http://purl.obolibrary.org/obo/CHEBI_73924"}],"text":"In COVID-19 the homeostatic equilibrium between TREG cells (IL-10) and Th17 cells (IL-17) is broken: inflammatory cytokine levels (IL-1, TNF) are elevated in the lungs of COVID-19 patients, resulting in an increase in HA-synthase-2 (HAS2) in alveolar epithelial cells CD31+, EpCAM+ and fibroblasts."}

{"project":"LitCovid-sentences","denotations":[{"id":"T87","span":{"begin":0,"end":298},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In COVID-19 the homeostatic equilibrium between TREG cells (IL-10) and Th17 cells (IL-17) is broken: inflammatory cytokine levels (IL-1, TNF) are elevated in the lungs of COVID-19 patients, resulting in an increase in HA-synthase-2 (HAS2) in alveolar epithelial cells CD31+, EpCAM+ and fibroblasts."}

{"project":"LitCovid-PubTator","denotations":[{"id":"443","span":{"begin":60,"end":65},"obj":"Gene"},{"id":"444","span":{"begin":83,"end":88},"obj":"Gene"},{"id":"445","span":{"begin":131,"end":135},"obj":"Gene"},{"id":"446","span":{"begin":137,"end":140},"obj":"Gene"},{"id":"447","span":{"begin":218,"end":231},"obj":"Gene"},{"id":"448","span":{"begin":233,"end":237},"obj":"Gene"},{"id":"449","span":{"begin":268,"end":272},"obj":"Gene"},{"id":"450","span":{"begin":275,"end":280},"obj":"Gene"},{"id":"466","span":{"begin":180,"end":188},"obj":"Species"},{"id":"471","span":{"begin":3,"end":11},"obj":"Disease"},{"id":"472","span":{"begin":171,"end":179},"obj":"Disease"}],"attributes":[{"id":"A443","pred":"tao:has_database_id","subj":"443","obj":"Gene:3586"},{"id":"A444","pred":"tao:has_database_id","subj":"444","obj":"Gene:3605"},{"id":"A445","pred":"tao:has_database_id","subj":"445","obj":"Gene:3552"},{"id":"A446","pred":"tao:has_database_id","subj":"446","obj":"Gene:7124"},{"id":"A447","pred":"tao:has_database_id","subj":"447","obj":"Gene:3037"},{"id":"A448","pred":"tao:has_database_id","subj":"448","obj":"Gene:3037"},{"id":"A449","pred":"tao:has_database_id","subj":"449","obj":"Gene:5175"},{"id":"A450","pred":"tao:has_database_id","subj":"450","obj":"Gene:4072"},{"id":"A466","pred":"tao:has_database_id","subj":"466","obj":"Tax:9606"},{"id":"A471","pred":"tao:has_database_id","subj":"471","obj":"MESH:C000657245"},{"id":"A472","pred":"tao:has_database_id","subj":"472","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In COVID-19 the homeostatic equilibrium between TREG cells (IL-10) and Th17 cells (IL-17) is broken: inflammatory cytokine levels (IL-1, TNF) are elevated in the lungs of COVID-19 patients, resulting in an increase in HA-synthase-2 (HAS2) in alveolar epithelial cells CD31+, EpCAM+ and fibroblasts."}