PMC:7647877 / 12763-13046 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T222","span":{"begin":37,"end":44},"obj":"Body_part"},{"id":"T223","span":{"begin":81,"end":87},"obj":"Body_part"},{"id":"T224","span":{"begin":161,"end":166},"obj":"Body_part"}],"attributes":[{"id":"A222","pred":"fma_id","subj":"T222","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A223","pred":"fma_id","subj":"T223","obj":"http://purl.org/sig/ont/fma/fma82764"},{"id":"A224","pred":"fma_id","subj":"T224","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T43","span":{"begin":161,"end":166},"obj":"Body_part"}],"attributes":[{"id":"A43","pred":"uberon_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T69","span":{"begin":232,"end":243},"obj":"Disease"}],"attributes":[{"id":"A69","pred":"mondo_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/MONDO_0005468"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T223","span":{"begin":63,"end":73},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T224","span":{"begin":139,"end":140},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T225","span":{"begin":161,"end":166},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T226","span":{"begin":161,"end":166},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T227","span":{"begin":177,"end":179},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T228","span":{"begin":249,"end":259},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T150","span":{"begin":37,"end":44},"obj":"Chemical"},{"id":"T151","span":{"begin":81,"end":87},"obj":"Chemical"}],"attributes":[{"id":"A150","pred":"chebi_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A151","pred":"chebi_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T17","span":{"begin":232,"end":243},"obj":"Phenotype"}],"attributes":[{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0002615"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T72","span":{"begin":148,"end":175},"obj":"http://purl.obolibrary.org/obo/GO_0008217"},{"id":"T73","span":{"begin":201,"end":213},"obj":"http://purl.obolibrary.org/obo/GO_0042311"},{"id":"T74","span":{"begin":215,"end":226},"obj":"http://purl.obolibrary.org/obo/GO_0035815"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-sentences","denotations":[{"id":"T79","span":{"begin":0,"end":283},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}

{"project":"LitCovid-PubTator","denotations":[{"id":"337","span":{"begin":0,"end":3},"obj":"Gene"},{"id":"338","span":{"begin":97,"end":107},"obj":"Gene"},{"id":"339","span":{"begin":267,"end":273},"obj":"Gene"},{"id":"348","span":{"begin":81,"end":87},"obj":"Chemical"},{"id":"363","span":{"begin":232,"end":243},"obj":"Disease"}],"attributes":[{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"Gene:3827"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"Gene:9622"},{"id":"A339","pred":"tao:has_database_id","subj":"339","obj":"Gene:624"},{"id":"A348","pred":"tao:has_database_id","subj":"348","obj":"MESH:D012694"},{"id":"A363","pred":"tao:has_database_id","subj":"363","obj":"MESH:D007022"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"BDK is produced from an inactive pre-protein kininogen through activation by the serine protease kallikrein; in addition, it is considered a potent regulator of blood pressure [22], because it induces vasodilation, natriuresis, and hypotension upon activation of the BDKRB2 receptor."}