PMC:7646269 / 15426-16759
Annnotations
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Since one of the potential sequelae of COVID‐19 is secondary fungal infections as our cases demonstrated, vigilance for secondary infections will be needed to reduce adverse outcomes. Clinicians should have a high index of suspicion for CAPA when a critically ill patient with COVID‐19 in the ICU develops further respiratory decompensation, fevers or new or worsening radiographic abnormalities of the lungs, particularly if there is no response to empiric antibacterial therapy. It is important to obtain a respiratory culture for fungal pathogens and a serum galactomannan level in these settings to attempt to identify this ominous complication of COVID‐19.","tracks":[{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T9","span":{"begin":1234,"end":1247},"obj":"https://glytoucan.org/Structures/Glycans/G93424OB"}],"attributes":[{"subj":"T9","pred":"source","obj":"LitCovid_Glycan-Motif-Structure"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T29","span":{"begin":148,"end":152},"obj":"Body_part"},{"id":"T30","span":{"begin":1075,"end":1080},"obj":"Body_part"},{"id":"T31","span":{"begin":1228,"end":1233},"obj":"Body_part"}],"attributes":[{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma63083"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T30","span":{"begin":148,"end":152},"obj":"Body_part"},{"id":"T31","span":{"begin":1228,"end":1233},"obj":"Body_part"}],"attributes":[{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T109","span":{"begin":129,"end":133},"obj":"Disease"},{"id":"T110","span":{"begin":269,"end":277},"obj":"Disease"},{"id":"T111","span":{"begin":435,"end":439},"obj":"Disease"},{"id":"T112","span":{"begin":553,"end":561},"obj":"Disease"},{"id":"T113","span":{"begin":711,"end":719},"obj":"Disease"},{"id":"T114","span":{"begin":733,"end":750},"obj":"Disease"},{"id":"T115","span":{"begin":802,"end":812},"obj":"Disease"},{"id":"T116","span":{"begin":909,"end":913},"obj":"Disease"},{"id":"T117","span":{"begin":949,"end":957},"obj":"Disease"},{"id":"T118","span":{"begin":1324,"end":1332},"obj":"Disease"}],"attributes":[{"id":"A109","pred":"mondo_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/MONDO_0007163"},{"id":"A110","pred":"mondo_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A111","pred":"mondo_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/MONDO_0007163"},{"id":"A112","pred":"mondo_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A113","pred":"mondo_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A114","pred":"mondo_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/MONDO_0002041"},{"id":"A115","pred":"mondo_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A116","pred":"mondo_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/MONDO_0007163"},{"id":"A117","pred":"mondo_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T109","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T116","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T117","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T118","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T75","span":{"begin":251,"end":252},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T76","span":{"begin":879,"end":880},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T77","span":{"begin":919,"end":920},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T78","span":{"begin":1075,"end":1080},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T79","span":{"begin":1179,"end":1180},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T80","span":{"begin":1226,"end":1227},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T75","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T110","span":{"begin":31,"end":34},"obj":"Chemical"},{"id":"T112","span":{"begin":223,"end":226},"obj":"Chemical"},{"id":"T114","span":{"begin":235,"end":238},"obj":"Chemical"},{"id":"T116","span":{"begin":310,"end":313},"obj":"Chemical"},{"id":"T118","span":{"b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