PMC:7643666 / 22998-23515 JSONTXT

Taken together, our data point to Rhinolophus ferrumequinum as a potential primary reservoir for SARS-CoV-2 in Italy, and domestic and wild animal species can act as the second reservoir. However, the similarity of ACE2/spike protein complexes among these species does not explain the low human-to-animals transmission rate of SARS-CoV-2 infection. An innate or acquired resistance of domestic animals to the virus potentially accounts for the rare infection of domestic or wild animals occurring during the pandemic.