PMC:7643666 / 11969-12392 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7643666","sourcedb":"PMC","sourceid":"7643666","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7643666","text":"hACE2 receptor is essential for infection of SARS-CoV-2 in humans. The crystal structure of SARS-CoV-2 S receptor bound to ACE2 has been recently solved [9]. In a preliminary step, we analyzed hACE2/SARS-CoV-2 S complex and identified in hACE2 the residues K31, H34, E37, D38, Q42, K353, and N330 as those critical for the interaction with S protein; among them, K31 and K353, revealed to be critical for S recognition [1].","tracks":[{"project":"Zoonoses","denotations":[{"id":"T10","span":{"begin":199,"end":211},"obj":"Gene"},{"id":"T9","span":{"begin":92,"end":104},"obj":"Gene"}],"attributes":[{"id":"A10","pred":"tao:has_database_id","subj":"T10","obj":"Gene:43740568"},{"id":"A9","pred":"tao:has_database_id","subj":"T9","obj":"Gene:43740568"},{"subj":"T10","pred":"source","obj":"Zoonoses"},{"subj":"T9","pred":"source","obj":"Zoonoses"}]},{"project":"Covid19_manual_annotation_v2","denotations":[{"id":"T9","span":{"begin":92,"end":104},"obj":"Gene"},{"id":"T10","span":{"begin":199,"end":211},"obj":"Gene"}],"attributes":[{"id":"A9","pred":"tao:has_database_id","subj":"T9","obj":"Gene:43740568"},{"id":"A10","pred":"tao:has_database_id","subj":"T10","obj":"Gene:43740568"},{"subj":"T9","pred":"source","obj":"Covid19_manual_annotation_v2"},{"subj":"T10","pred":"source","obj":"Covid19_manual_annotation_v2"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"BioProject","uri":"https://www.ncbi.nlm.nih.gov/bioproject/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"},{"prefix":"HP","uri":"https://hpo.jax.org/app/browse/term/HP:"},{"prefix":"BioSample","uri":"https://www.ncbi.nlm.nih.gov/biosample/"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Zoonoses","color":"#93eaec","default":true},{"id":"Covid19_manual_annotation_v2","color":"#ecd493"}]}]}}