> top > docs > PMC:7640975 > spans > 1660-63431 > annotations

PMC:7640975 / 1660-63431 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T47 3972-3980 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T16 104-107 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T17 108-114 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T18 941-956 Body_part denotes small intestine http://purl.org/sig/ont/fma/fma7200
T19 984-991 Body_part denotes jejunum http://purl.org/sig/ont/fma/fma7207
T20 996-1001 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T21 1055-1071 Body_part denotes small intestinal http://purl.org/sig/ont/fma/fma7200
T22 1072-1088 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T23 1083-1088 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T24 1219-1225 Body_part denotes villus http://purl.org/sig/ont/fma/fma82505
T25 1277-1293 Body_part denotes small intestinal http://purl.org/sig/ont/fma/fma7200
T26 1294-1305 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T27 1378-1382 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T28 1422-1429 Body_part denotes jejunum http://purl.org/sig/ont/fma/fma7207
T29 1518-1528 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T30 1537-1553 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T31 1548-1553 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 1633-1637 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T33 1665-1670 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T34 1780-1796 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T35 1791-1796 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T36 2002-2007 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T37 2262-2266 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T38 2306-2310 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T39 2348-2352 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T40 2491-2496 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T41 2596-2600 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T42 2766-2771 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 2808-2811 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T44 3065-3070 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T45 3431-3442 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T46 3446-3450 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T48 4142-4146 Body_part denotes foot http://purl.org/sig/ont/fma/fma9664
T49 4151-4156 Body_part denotes mouth http://purl.org/sig/ont/fma/fma49184
T50 4605-4610 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 4771-4776 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T52 4782-4792 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T53 4893-4903 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T54 4953-4959 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T55 4968-4973 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 5038-5044 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T57 5121-5126 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T58 5248-5253 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T59 5383-5388 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T60 5430-5437 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365
T61 5603-5608 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T62 5723-5731 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T63 5782-5789 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T64 5835-5840 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T65 6015-6031 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T66 6033-6036 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T67 6114-6117 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T68 6195-6200 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T69 6429-6433 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T70 6476-6481 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 6520-6525 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T72 6608-6613 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T73 6747-6752 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T74 6979-6984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T75 7153-7158 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T76 7275-7280 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T77 7561-7566 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T78 7696-7700 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T79 7753-7758 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T80 7859-7864 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T81 8022-8025 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T82 8070-8075 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T83 8139-8144 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T84 8226-8233 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T85 8343-8348 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T86 8379-8384 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T87 8466-8470 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T88 8637-8641 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T89 8806-8810 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T90 9022-9030 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T91 9053-9060 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T92 9103-9110 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T93 9180-9188 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T94 9404-9411 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T95 9456-9464 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T96 9623-9630 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T97 9760-9767 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T98 9893-9900 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T99 10116-10123 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T100 11868-11877 Body_part denotes capillary http://purl.org/sig/ont/fma/fma63194
T101 13261-13269 Body_part denotes cysteine http://purl.org/sig/ont/fma/fma82751
T102 13367-13374 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T103 13710-13717 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T104 13836-13843 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T105 13986-13994 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T106 14036-14041 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T107 14052-14060 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T108 14316-14321 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 14340-14344 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T110 14771-14778 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T111 14965-14972 Body_part denotes Genomes http://purl.org/sig/ont/fma/fma84116
T112 15476-15483 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T113 15484-15491 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T114 15820-15824 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T115 15943-15946 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T116 15988-15993 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 16044-16047 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T118 16141-16144 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T119 16380-16385 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T120 16404-16408 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T121 16522-16527 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T122 16851-16856 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T123 17323-17328 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T124 17468-17473 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T125 17484-17488 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T126 17616-17623 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T127 17650-17655 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T128 17704-17712 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T129 17771-17776 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T130 17802-17809 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T131 17997-18001 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T132 18084-18088 Body_part denotes milk http://purl.org/sig/ont/fma/fma62100
T133 18188-18193 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T134 18400-18407 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T135 19589-19594 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T136 19683-19687 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T137 19844-19849 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T138 19875-19880 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T139 19990-19995 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T140 20014-20019 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T141 20172-20180 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T142 20503-20508 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T143 20634-20638 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T144 20758-20763 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T145 20791-20796 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T146 20823-20828 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T147 21053-21057 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T148 21112-21121 Body_part denotes cytoplasm http://purl.org/sig/ont/fma/fma66835
T149 21198-21202 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T150 21223-21227 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T151 21411-21416 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T152 21469-21474 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T153 21568-21573 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 21644-21651 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T155 21698-21703 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 21996-22013 Body_part denotes cellular membrane http://purl.org/sig/ont/fma/fma63841
T157 22017-22029 Body_part denotes cytoskeleton http://purl.org/sig/ont/fma/fma63834
T158 22261-22266 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T159 22312-22317 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T160 22356-22361 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T161 22429-22433 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T162 22565-22570 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T163 22689-22692 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T164 22712-22717 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T165 22758-22762 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T166 22873-22878 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T167 23099-23104 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T168 23203-23211 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T169 23260-23265 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T170 23380-23388 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T171 23446-23451 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T172 23601-23609 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T173 23648-23656 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T174 23711-23716 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T175 23754-23759 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 23792-23800 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T177 23829-23836 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T178 23844-23851 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T179 23862-23869 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T180 23906-23914 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T181 23999-24004 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T182 24195-24199 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T183 24368-24376 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T184 24508-24514 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T185 24585-24591 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T186 24645-24653 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T187 24725-24733 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T188 24800-24808 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T189 24849-24854 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T190 24886-24893 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T191 25021-25029 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T192 25048-25053 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T193 25201-25208 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T194 25358-25365 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T195 25385-25395 Body_part denotes methionine http://purl.org/sig/ont/fma/fma82759
T196 25414-25421 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T197 25507-25514 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T198 25667-25669 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T199 25725-25732 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T200 25804-25811 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T201 25903-25914 Body_part denotes Nucleoporin http://purl.org/sig/ont/fma/fma67688
T202 26066-26069 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T203 26108-26111 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T204 26128-26135 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T205 26198-26201 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T206 26223-26239 Body_part denotes Collagen type IV http://purl.org/sig/ont/fma/fma63906
T207 26223-26231 Body_part denotes Collagen http://purl.org/sig/ont/fma/fma63891
T208 26298-26327 Body_part denotes glomerular basement membranes http://purl.org/sig/ont/fma/fma74274
T209 26765-26779 Body_part denotes Interleukin 13 http://purl.org/sig/ont/fma/fma264824
T210 26765-26776 Body_part denotes Interleukin http://purl.org/sig/ont/fma/fma86578
T211 26877-26885 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T212 26954-26957 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T213 26996-27005 Body_part denotes Prolactin http://purl.org/sig/ont/fma/fma83358
T214 27173-27176 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T215 27262-27269 Body_part denotes Tubulin http://purl.org/sig/ont/fma/fma67116
T216 27292-27300 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T217 27319-27324 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T218 27330-27353 Body_part denotes low density lipoprotein http://purl.org/sig/ont/fma/fma63170
T219 27543-27546 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T220 27629-27632 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T221 27900-27906 Body_part denotes finger http://purl.org/sig/ont/fma/fma9666
T222 28057-28064 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T223 28081-28084 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T224 28212-28221 Body_part denotes Chromatin http://purl.org/sig/ont/fma/fma67526
T225 28320-28323 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T226 28444-28447 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T227 28604-28619 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T228 28615-28619 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T229 28634-28641 Body_part denotes Myocyte http://purl.org/sig/ont/fma/fma67328
T230 28701-28708 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T231 28854-28861 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T232 28903-28910 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T233 28911-28917 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T234 28918-28927 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T235 29032-29039 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T236 29056-29077 Body_part denotes Transmembrane protein http://purl.org/sig/ont/fma/fma67858
T237 29131-29135 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T238 29191-29193 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T239 29264-29271 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T240 29314-29322 Body_part denotes Cadherin http://purl.org/sig/ont/fma/fma61790
T241 29331-29344 Body_part denotes Ribosomal RNA http://purl.org/sig/ont/fma/fma67118
T242 29341-29344 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T243 29345-29352 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T244 29417-29421 Body_part denotes rRNA http://purl.org/sig/ont/fma/fma67118
T245 29423-29430 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T246 29473-29481 Body_part denotes tyrosine http://purl.org/sig/ont/fma/fma82768
T247 29523-29530 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T248 29531-29537 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T249 29538-29547 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T250 29689-29696 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T251 29760-29767 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T252 29768-29774 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T253 29775-29784 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T254 29845-29853 Body_part denotes Cysteine http://purl.org/sig/ont/fma/fma82751
T255 30014-30021 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T256 30022-30028 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T257 30029-30038 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T258 30078-30085 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T259 30086-30092 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T260 30093-30102 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T261 30142-30149 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T262 30202-30212 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T263 30237-30244 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T264 30462-30468 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T265 30469-30478 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T266 30479-30486 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T267 30555-30558 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T268 30588-30595 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T269 30640-30643 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T270 30764-30771 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T271 30835-30842 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T272 31060-31078 Body_part denotes Actin cytoskeleton http://purl.org/sig/ont/fma/fma84684
T273 31060-31065 Body_part denotes Actin http://purl.org/sig/ont/fma/fma67843
T274 31122-31133 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T275 31134-31141 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T276 31288-31295 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T277 31329-31336 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T278 31347-31355 Body_part denotes Cadherin http://purl.org/sig/ont/fma/fma61790
T279 31502-31510 Body_part denotes ribosome http://purl.org/sig/ont/fma/fma66867
T280 31522-31529 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T281 31603-31611 Body_part denotes ribosome http://purl.org/sig/ont/fma/fma66867
T282 31623-31630 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T283 31737-31744 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T284 31780-31787 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T285 31822-31829 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T286 32031-32038 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T287 32092-32099 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T288 32141-32144 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T289 32212-32218 Body_part denotes Serine http://purl.org/sig/ont/fma/fma82764
T290 32251-32258 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T291 32259-32271 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T292 32326-32338 Body_part denotes Glycoprotein http://purl.org/sig/ont/fma/fma62925
T293 32971-32976 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T294 33063-33066 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T295 33090-33095 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T296 33162-33166 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T297 33193-33201 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T298 33268-33273 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T299 33322-33327 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T300 33536-33544 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T301 33556-33561 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T302 33836-33841 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T303 33898-33905 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T304 33934-33939 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T305 33947-33952 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T306 33986-33993 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T307 34022-34027 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T308 34035-34040 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T309 34552-34556 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T310 34605-34610 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T311 34641-34646 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T312 34736-34740 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T313 34772-34775 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T314 34933-34938 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T315 34959-34963 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T316 35133-35138 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T317 35172-35177 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T318 35381-35389 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T319 35401-35406 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T320 35437-35442 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T321 35532-35536 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T322 35553-35558 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T323 35707-35712 Body_part denotes Actin http://purl.org/sig/ont/fma/fma67843
T324 36005-36010 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T325 36243-36251 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T326 36392-36400 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T327 36469-36482 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T328 36850-36858 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T329 36950-36957 Body_part denotes synapse http://purl.org/sig/ont/fma/fma67408
T330 36991-37000 Body_part denotes organelle http://purl.org/sig/ont/fma/fma63832
T331 37006-37015 Body_part denotes cell part http://purl.org/sig/ont/fma/fma61764
T332 37006-37010 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T333 37092-37101 Body_part denotes organelle http://purl.org/sig/ont/fma/fma63832
T334 37106-37115 Body_part denotes cell part http://purl.org/sig/ont/fma/fma61764
T335 37106-37110 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T336 37161-37169 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T337 37490-37498 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T338 37521-37526 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T339 37606-37614 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T340 37620-37628 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T341 37891-37899 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T342 37942-37950 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T343 38052-38060 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T344 38547-38555 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T345 38674-38682 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T346 38735-38743 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T347 38778-38786 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T348 38838-38846 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T349 38868-38875 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T350 38936-38944 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T351 39025-39033 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T352 39055-39058 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T353 39090-39098 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T354 39120-39129 Body_part denotes chromatin http://purl.org/sig/ont/fma/fma67526
T355 39156-39164 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T356 39186-39198 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T357 39231-39239 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T358 39312-39322 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T359 39349-39354 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T360 39394-39403 Body_part denotes ribosomal http://purl.org/sig/ont/fma/fma66867
T361 39431-39435 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T362 39541-39553 Body_part denotes cytoskeleton http://purl.org/sig/ont/fma/fma63834
T363 39574-39582 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T364 39725-39733 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T365 39848-39856 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T366 39879-39884 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T367 40046-40054 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T368 40374-40382 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T369 40447-40460 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T370 40462-40478 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T371 40761-40769 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T372 41032-41040 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T373 41252-41259 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T374 41297-41304 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T375 41826-41830 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T376 41831-41835 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T377 41844-41861 Body_part denotes glycosaminoglycan http://purl.org/sig/ont/fma/fma63011
T378 41898-41904 Body_part denotes oocyte http://purl.org/sig/ont/fma/fma18644
T379 42218-42226 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T380 42249-42254 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T381 42344-42352 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T382 42688-42696 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T383 42784-42792 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T384 42865-42873 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T385 42944-42952 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T386 43306-43313 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T387 43314-43321 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T388 43380-43387 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T389 43479-43486 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T390 43487-43494 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T391 43656-43663 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T392 43835-43843 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T393 44051-44055 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T394 44110-44118 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T395 44130-44138 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T396 44383-44391 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T397 44520-44524 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T398 44631-44639 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T399 44687-44694 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T400 44752-44757 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T401 44855-44862 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T402 44863-44870 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T403 44927-44935 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T404 44958-44963 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T405 45118-45125 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T406 45195-45203 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T407 45397-45402 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T408 45526-45534 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T409 46039-46046 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T410 46064-46069 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T411 46195-46200 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T412 46219-46223 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T413 46271-46276 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T414 46365-46376 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T415 46457-46462 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T416 46713-46718 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T417 46735-46743 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T418 46782-46790 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T419 46864-46872 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T420 46937-46945 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T421 47131-47138 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T422 47348-47353 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T423 47440-47444 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T424 47534-47539 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T425 47743-47747 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T426 47855-47860 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T427 48237-48241 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T428 48403-48407 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T429 48445-48453 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T430 48576-48584 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T431 48678-48691 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T432 48714-48718 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T433 48736-48744 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T434 48918-48925 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T435 48960-48967 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T436 49033-49040 Body_part denotes synapse http://purl.org/sig/ont/fma/fma67408
T437 49074-49081 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T438 49096-49100 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T439 49139-49146 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T440 49258-49266 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T441 49628-49636 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T442 49644-49650 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T443 49756-49769 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T444 49786-49794 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T445 49973-49981 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T446 50096-50105 Body_part denotes chromatin http://purl.org/sig/ont/fma/fma67526
T447 50138-50146 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T448 50361-50369 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T449 50990-50998 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T450 51115-51123 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T451 51175-51188 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T452 51224-51232 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T453 51267-51283 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T454 51319-51327 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T455 51415-51423 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T456 51489-51496 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T457 51585-51592 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T458 51736-51749 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T459 51869-51872 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T460 52091-52104 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T461 52160-52176 Body_part denotes type IV collagen http://purl.org/sig/ont/fma/fma63906
T462 52321-52337 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T463 52357-52364 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T464 52393-52411 Body_part denotes basement membranes http://purl.org/sig/ont/fma/fma63872
T465 52482-52499 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T466 52494-52499 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T467 52523-52531 Body_part denotes integrin http://purl.org/sig/ont/fma/fma67222
T468 52766-52775 Body_part denotes cytosolic http://purl.org/sig/ont/fma/fma66836
T469 52862-52865 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T470 53206-53214 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T471 53320-53325 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T472 53342-53350 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T473 53625-53630 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T474 53824-53829 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T475 53863-53868 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T476 54134-54139 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T477 54504-54511 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T478 54602-54605 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T479 54783-54788 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T480 55112-55116 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T481 55259-55264 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T482 55277-55284 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T483 55963-55968 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T484 56170-56175 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T485 56300-56305 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T486 56335-56339 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T487 56960-56964 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T488 57182-57187 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T489 57287-57291 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T490 57442-57450 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T491 57475-57479 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T492 57546-57558 Body_part denotes nuclear pore http://purl.org/sig/ont/fma/fma63148
T493 57663-57679 Body_part denotes nuclear envelope http://purl.org/sig/ont/fma/fma63888
T494 57842-57846 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T495 57865-57868 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T496 58039-58042 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T497 58157-58160 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T498 58585-58588 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T499 58599-58602 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T500 58681-58684 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T501 58878-58883 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T502 58949-58953 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T503 59103-59108 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T504 59600-59605 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T505 60020-60025 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T506 60188-60198 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T507 60493-60498 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T508 60625-60630 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T509 60962-60969 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T510 61005-61010 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T511 61137-61145 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T512 61167-61175 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T513 61219-61224 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T514 61391-61407 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T515 61409-61422 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T516 61501-61505 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T517 61765-61770 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T4 941-956 Body_part denotes small intestine http://purl.obolibrary.org/obo/UBERON_0002108
T5 947-956 Body_part denotes intestine http://purl.obolibrary.org/obo/UBERON_0000160
T6 984-991 Body_part denotes jejunum http://purl.obolibrary.org/obo/UBERON_0002115
T7 996-1001 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T8 1026-1032 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T9 1055-1071 Body_part denotes small intestinal http://purl.obolibrary.org/obo/UBERON_0002108
T10 1277-1293 Body_part denotes small intestinal http://purl.obolibrary.org/obo/UBERON_0002108
T11 1422-1429 Body_part denotes jejunum http://purl.obolibrary.org/obo/UBERON_0002115
T12 2348-2352 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T13 4142-4146 Body_part denotes foot http://purl.obolibrary.org/obo/UBERON_0002387
T14 4151-4156 Body_part denotes mouth http://purl.obolibrary.org/obo/UBERON_0000165
T15 4953-4959 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T16 5038-5044 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T17 5383-5388 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T18 6520-6525 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T19 7275-7280 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T20 11868-11877 Body_part denotes capillary http://purl.obolibrary.org/obo/UBERON_0001982
T21 18084-18088 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913
T22 22495-22500 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T23 22808-22813 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T24 26298-26327 Body_part denotes glomerular basement membranes http://purl.obolibrary.org/obo/UBERON_0005777
T25 27900-27906 Body_part denotes finger http://purl.obolibrary.org/obo/UBERON_0002389
T26 36469-36482 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T27 37006-37015 Body_part denotes cell part http://purl.obolibrary.org/obo/UBERON_0000470
T28 37106-37115 Body_part denotes cell part http://purl.obolibrary.org/obo/UBERON_0000470
T29 40447-40460 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T30 40462-40478 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T31 41831-41835 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T32 48678-48691 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T33 49651-49656 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T34 49756-49769 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T35 51175-51188 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T36 51267-51283 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T37 51736-51749 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T38 52091-52104 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T39 52321-52337 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T40 52464-52468 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T41 57554-57558 Body_part denotes pore http://purl.obolibrary.org/obo/UBERON_0008915
T42 61391-61407 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T43 61409-61422 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T3 353-371 Disease denotes diarrheal diseases http://purl.obolibrary.org/obo/MONDO_0001673
T4 402-411 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 671-679 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T6 764-773 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 1193-1202 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 1871-1879 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T9 1914-1929 Disease denotes gastroenteritis http://purl.obolibrary.org/obo/MONDO_0002269
T10 2039-2048 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T11 3165-3181 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T12 4142-4164 Disease denotes foot-and-mouth disease http://purl.obolibrary.org/obo/MONDO_0005765
T13 4151-4164 Disease denotes mouth disease http://purl.obolibrary.org/obo/MONDO_0006858
T14 4219-4240 Disease denotes classical swine fever http://purl.obolibrary.org/obo/MONDO_0025087
T15 4632-4641 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T16 4803-4806 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T17 4930-4938 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T18 5053-5063 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T19 6252-6259 Disease denotes sterile http://purl.obolibrary.org/obo/MONDO_0005047
T20 6355-6358 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T21 6395-6404 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T22 6504-6511 Disease denotes sterile http://purl.obolibrary.org/obo/MONDO_0005047
T23 14547-14549 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T25 19823-19832 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 20386-20395 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T27 20484-20493 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T28 20924-20933 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T29 22386-22389 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T30 22918-22933 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T31 22924-22933 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T32 23126-23135 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T33 23167-23182 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T34 23173-23182 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 23915-23918 Disease denotes NS6 http://purl.obolibrary.org/obo/MONDO_0013186
T36 23923-23926 Disease denotes NS7 http://purl.obolibrary.org/obo/MONDO_0013379
T37 24876-24885 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T38 24936-24945 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T39 26329-26332 Disease denotes GBM http://purl.obolibrary.org/obo/MONDO_0018177
T40 27484-27500 Disease denotes Myeloid leukemia http://purl.obolibrary.org/obo/MONDO_0004643
T41 27492-27500 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059
T42 29124-29130 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T43 30827-30834 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T44 33701-33710 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T45 34096-34105 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T46 34622-34631 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T47 34693-34696 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T48 35418-35427 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T49 35489-35492 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T50 36359-36361 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T52 37144-37146 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T54 37538-37547 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T55 37747-37749 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T57 39896-39905 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 40399-40424 Disease denotes viral infectious diseases http://purl.obolibrary.org/obo/MONDO_0005108
T59 40405-40415 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T60 40462-40490 Disease denotes digestive system and cancers http://purl.obolibrary.org/obo/MONDO_0002516
T61 40997-41003 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T62 41630-41639 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T63 41641-41671 Disease denotes human papillomavirus infection http://purl.obolibrary.org/obo/MONDO_0005161
T64 41662-41671 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T65 41756-41762 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T66 41764-41773 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T67 41777-41784 Disease denotes measles http://purl.obolibrary.org/obo/MONDO_0004619
T68 41820-41842 Disease denotes small cell lung cancer http://purl.obolibrary.org/obo/MONDO_0008433
T69 41831-41842 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T70 41836-41842 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T71 42093-42113 Disease denotes diseases, metabolism http://purl.obolibrary.org/obo/MONDO_0005066
T72 42266-42275 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T73 42536-42538 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T74 44437-44446 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T75 44731-44740 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T76 44975-44984 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T77 45602-45617 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T78 45608-45617 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T79 45868-45884 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T80 46075-46084 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T81 46326-46335 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T82 46411-46420 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T83 46621-46630 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T84 46918-46921 Disease denotes NS6 http://purl.obolibrary.org/obo/MONDO_0013186
T85 46923-46926 Disease denotes NS7 http://purl.obolibrary.org/obo/MONDO_0013379
T86 47556-47565 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T87 49430-49432 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T89 50929-50953 Disease denotes viral infectious disease http://purl.obolibrary.org/obo/MONDO_0005108
T90 50935-50953 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T91 51373-51379 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T92 51706-51731 Disease denotes viral infectious diseases http://purl.obolibrary.org/obo/MONDO_0005108
T93 51712-51722 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T94 52061-52086 Disease denotes viral infectious diseases http://purl.obolibrary.org/obo/MONDO_0005108
T95 52067-52077 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T96 52274-52298 Disease denotes viral infectious disease http://purl.obolibrary.org/obo/MONDO_0005108
T97 52280-52298 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T98 52321-52350 Disease denotes digestive system, and cancers http://purl.obolibrary.org/obo/MONDO_0002516
T99 52598-52603 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T100 53428-53444 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T101 53527-53536 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T102 53636-53645 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T103 54512-54515 Disease denotes NS6 http://purl.obolibrary.org/obo/MONDO_0013186
T104 55448-55456 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T105 55461-55467 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T106 56116-56125 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T107 56259-56268 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T108 56439-56448 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T109 58285-58291 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T110 58293-58316 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T111 58443-58452 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T112 58462-58468 Disease denotes dengue http://purl.obolibrary.org/obo/MONDO_0005502
T113 58504-58520 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T114 58618-58627 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T115 59120-59129 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T116 59323-59370 Disease denotes severe acute respiratory syndrome coronavirus-2 http://purl.obolibrary.org/obo/MONDO_0100096
T117 59323-59356 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T118 59372-59380 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 59407-59431 Disease denotes Coronavirus Disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T120 59433-59441 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 59620-59628 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T122 59631-59640 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T123 59744-59752 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 59755-59764 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T125 59925-59933 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T126 60041-60049 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T127 60052-60061 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T128 60231-60246 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T129 60237-60246 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T130 60369-60377 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 60472-60480 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T132 60600-60608 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T27 66-69 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T28 70-71 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 271-272 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 470-475 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T31 476-479 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T32 796-799 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T33 878-881 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T34 941-956 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestine
T35 984-991 http://purl.obolibrary.org/obo/UBERON_0002115 denotes jejunum
T36 996-1001 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T37 1026-1032 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T38 1055-1071 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestinal
T39 1072-1082 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T40 1083-1088 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T41 1277-1293 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestinal
T42 1378-1387 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T43 1422-1429 http://purl.obolibrary.org/obo/UBERON_0002115 denotes jejunum
T44 1433-1434 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 1463-1466 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T46 1518-1528 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T47 1518-1528 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T48 1537-1547 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T49 1548-1553 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T50 1554-1556 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T51 1633-1643 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T52 1665-1670 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T53 1780-1790 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T54 1791-1796 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T55 1817-1824 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T56 1880-1885 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T57 1930-1935 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T58 2002-2007 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T59 2063-2064 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T60 2239-2240 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 2241-2246 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T62 2255-2256 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 2262-2266 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T64 2306-2310 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T65 2319-2324 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T66 2367-2372 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T67 2459-2464 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T68 2491-2496 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T69 2560-2565 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T70 2590-2595 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T71 2596-2600 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T72 2706-2707 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 2760-2771 http://purl.obolibrary.org/obo/CLO_0052500 denotes PK-15 cells
T74 2858-2863 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T75 2952-2958 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T76 3065-3070 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T77 3252-3257 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T78 3258-3260 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T79 3419-3427 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeling
T80 3446-3450 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T81 3526-3528 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T82 3533-3538 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T83 3673-3675 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T84 3676-3678 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T85 3679-3681 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T86 3692-3695 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T87 3870-3871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 4013-4016 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T89 4075-4080 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T90 4131-4133 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T91 4151-4156 http://www.ebi.ac.uk/efo/EFO_0000825 denotes mouth
T92 4165-4170 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T93 4241-4246 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T94 4282-4283 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 4338-4343 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T96 4390-4391 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 4457-4460 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T98 4492-4497 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T99 4550-4552 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T100 4553-4555 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T101 4556-4558 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T102 4605-4610 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T103 4764-4769 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T104 4771-4776 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T105 4807-4809 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T106 4893-4903 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T107 4893-4903 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T108 4916-4917 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 4953-4959 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T110 4953-4959 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T111 4953-4959 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T112 4960-4973 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T113 5016-5017 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T114 5094-5099 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T115 5121-5126 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T116 5248-5253 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T117 5430-5437 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T118 5493-5495 http://purl.obolibrary.org/obo/CLO_0009141 denotes St
T119 5493-5495 http://purl.obolibrary.org/obo/CLO_0050980 denotes St
T120 5504-5506 http://purl.obolibrary.org/obo/CLO_0007815 denotes MO
T121 5603-5608 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T122 5635-5636 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 5822-5827 http://purl.obolibrary.org/obo/CLO_0007836 denotes Mouse
T124 5846-5851 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T125 5993-5997 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T126 6099-6103 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T127 6169-6174 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T128 6195-6200 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T129 6359-6361 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T130 6377-6378 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 6425-6433 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T132 6476-6481 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T133 6608-6613 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T134 6747-6752 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T135 6979-6984 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T136 7030-7031 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 7153-7158 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T138 7198-7200 http://purl.obolibrary.org/obo/CLO_0009877 denotes NY
T139 7376-7378 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T140 7394-7399 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T141 7535-7537 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T142 7561-7566 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T143 7692-7700 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T144 7708-7709 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T145 7710-7712 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T146 7753-7758 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T147 7859-7864 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T148 8007-8011 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T149 8070-8075 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T150 8139-8144 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T151 8267-8275 http://purl.obolibrary.org/obo/CLO_0007225 denotes Labeling
T152 8343-8348 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T153 8379-8384 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T154 8466-8470 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T155 8637-8641 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T156 8806-8810 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T157 8955-8959 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4 °C
T158 9090-9091 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 9328-9330 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T160 9331-9333 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T161 9334-9336 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T162 9375-9383 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeling
T163 9481-9482 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 9532-9533 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T165 9720-9721 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 9913-9914 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 9995-9999 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4 °C
T168 10233-10241 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T169 10334-10342 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T170 10353-10360 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T171 10561-10568 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T172 10591-10594 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T173 10691-10698 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T174 10710-10713 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T175 10736-10739 http://purl.obolibrary.org/obo/CLO_0001053 denotes 121
T176 10749-10756 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T177 10988-10989 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T178 11026-11027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T179 11176-11177 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T180 11212-11214 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T181 11215-11217 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T182 11218-11220 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T183 11230-11232 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T184 11233-11235 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T185 11236-11238 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T186 11255-11262 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T187 11263-11271 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T188 11295-11296 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T189 11464-11471 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T190 11472-11480 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T191 11486-11487 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 11547-11555 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T193 11592-11593 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 11658-11659 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T195 11734-11735 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T196 11977-11978 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T197 12051-12053 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T198 12058-12060 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T199 12061-12063 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T200 12065-12066 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T201 12072-12074 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T202 12214-12215 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T203 12248-12250 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T204 12351-12353 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T205 12354-12356 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T206 12433-12440 http://purl.obolibrary.org/obo/CLO_0001040 denotes 1 × 105
T207 12461-12463 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T208 12492-12494 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T209 12572-12574 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T210 12602-12604 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T211 12605-12607 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T212 13233-13243 http://purl.obolibrary.org/obo/OBI_0000968 denotes instrument
T213 13588-13590 http://www.ebi.ac.uk/efo/EFO_0000265 denotes Da
T214 13655-13657 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T215 13698-13705 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T216 13784-13785 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 13824-13831 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T218 13867-13871 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T219 14036-14041 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T220 14066-14067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T221 14099-14102 http://purl.obolibrary.org/obo/CLO_0001547 denotes a p
T222 14316-14321 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T223 14340-14344 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T224 14498-14516 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular component
T225 14518-14520 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T226 14686-14690 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T227 14707-14710 http://purl.obolibrary.org/obo/CLO_0001547 denotes a p
T228 14955-14960 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Genes
T229 15188-15189 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T230 15207-15215 http://purl.obolibrary.org/obo/CLO_0001040 denotes 1 × 10–5
T231 15373-15377 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T232 15988-15993 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T233 16154-16155 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T234 16298-16299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T235 16389-16390 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 16404-16408 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T237 16528-16533 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T238 16969-16973 http://purl.obolibrary.org/obo/CLO_0001564 denotes a 20
T239 16969-16973 http://purl.obolibrary.org/obo/CLO_0050194 denotes a 20
T240 17190-17191 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T241 17484-17488 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T242 17771-17776 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T243 17916-17925 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T244 17962-17963 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T245 17997-18001 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T246 18036-18045 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T247 18068-18071 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T248 18102-18106 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4 °C
T249 18278-18287 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T250 18421-18430 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T251 18551-18552 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T252 18673-18675 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T253 18676-18678 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T254 18679-18681 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T255 19091-19093 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T256 19268-19272 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T257 19358-19359 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T258 19589-19594 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T259 19683-19687 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T260 19707-19709 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T261 19803-19804 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T262 19844-19849 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T263 19875-19880 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T264 19976-19981 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T265 19990-19995 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T266 20014-20019 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T267 20503-20508 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T268 20593-20597 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4, 8
T269 20611-20613 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T270 20634-20638 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T271 20758-20763 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T272 20791-20796 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T273 20823-20828 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T274 21017-21019 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T275 21053-21057 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T276 21198-21202 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T277 21223-21227 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T278 21395-21397 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T279 21395-21397 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T280 21403-21416 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T281 21417-21419 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T282 21434-21436 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T283 21469-21474 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T284 21568-21573 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T285 21600-21601 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T286 21698-21703 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T287 21795-21800 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T288 21815-21816 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T289 21868-21869 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T290 22005-22013 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T291 22084-22085 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T292 22105-22107 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T293 22261-22266 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T294 22312-22317 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T295 22320-22321 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T296 22356-22361 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T297 22390-22392 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T298 22429-22433 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T299 22457-22461 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4, 8
T300 22475-22477 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T301 22511-22517 http://purl.obolibrary.org/obo/PR_000010213 denotes m. (B)
T302 22565-22570 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T303 22666-22673 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T304 22674-22678 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T305 22712-22717 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T306 22738-22739 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T307 22758-22762 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T308 22873-22878 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T309 22948-22953 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T310 23099-23104 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T311 23260-23265 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T312 23338-23340 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T313 23341-23343 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T314 23344-23346 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T315 23446-23451 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T316 23482-23484 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T317 23711-23716 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T318 23754-23759 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T319 23853-23861 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T320 23915-23918 http://purl.obolibrary.org/obo/OGG_3000004893 denotes NS6
T321 23923-23926 http://purl.obolibrary.org/obo/CLO_0008201 denotes NS7
T322 23947-23949 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T323 23947-23949 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T324 23999-24004 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T325 24195-24199 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T326 24461-24463 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T327 24579-24584 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T328 24694-24695 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T329 24849-24854 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T330 24956-24964 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T331 25048-25053 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T332 25098-25100 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T333 25270-25275 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T334 25482-25487 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T335 25620-25625 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T336 25812-25815 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T337 25854-25862 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T338 25885-25902 http://purl.obolibrary.org/obo/PR_000024990 denotes type I interferon
T339 26099-26107 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T340 26156-26157 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T341 26214-26222 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T342 26223-26231 http://purl.obolibrary.org/obo/CHEBI_3815 denotes Collagen
T343 26309-26327 http://purl.obolibrary.org/obo/UBERON_0005769 denotes basement membranes
T344 26329-26332 http://purl.obolibrary.org/obo/CLO_0003456 denotes GBM
T345 26346-26348 http://purl.obolibrary.org/obo/CLO_0050160 denotes T2
T346 26393-26395 http://purl.obolibrary.org/obo/CLO_0050160 denotes T2
T347 26396-26404 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T348 26689-26697 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T349 26846-26852 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T350 26864-26872 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T351 26895-26903 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T352 26904-26907 http://purl.obolibrary.org/obo/OGG_3000002353 denotes FOS
T353 26987-26995 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T354 26996-27005 http://purl.obolibrary.org/obo/PR_000013246 denotes Prolactin
T355 27072-27081 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T356 27082-27090 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T357 27095-27105 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T358 27194-27202 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T359 27319-27324 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T360 27650-27658 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T361 27914-27916 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T362 28072-28080 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T363 28144-28152 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T364 28203-28211 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T365 28248-28249 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T366 28346-28347 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T367 28432-28440 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T368 28604-28614 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T369 28615-28619 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T370 28634-28641 http://purl.obolibrary.org/obo/CL_0000187 denotes Myocyte
T371 28722-28730 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T372 28827-28835 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T373 28844-28853 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T374 28935-28943 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T375 29047-29055 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T376 29131-29135 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T377 29234-29242 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T378 29314-29322 http://purl.obolibrary.org/obo/PR_000001327 denotes Cadherin
T379 29458-29466 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T380 29555-29563 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T381 29792-29800 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T382 29883-29891 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T383 30110-30118 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T384 30192-30200 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T385 30335-30344 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T386 30399-30401 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T387 30441-30449 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T388 30546-30554 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T389 30733-30741 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T390 31079-31091 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T391 31185-31193 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T392 31279-31287 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T393 31347-31355 http://purl.obolibrary.org/obo/PR_000001327 denotes Cadherin
T394 31484-31492 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T395 31635-31637 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T396 31648-31649 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T397 31847-31855 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T398 31957-31965 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T399 31966-31972 http://purl.obolibrary.org/obo/SO_0000418 denotes Signal
T400 31973-31980 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T401 32056-32064 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T402 32238-32246 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T403 32359-32367 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T404 32476-32478 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T405 32632-32635 http://purl.obolibrary.org/obo/CLO_0051142 denotes Rho
T406 32796-32798 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T407 32799-32801 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T408 32802-32804 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T409 32971-32976 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T410 33090-33095 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T411 33145-33147 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T412 33268-33273 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T413 33322-33327 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T414 33384-33386 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T415 33556-33561 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T416 33634-33640 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T417 33836-33841 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T418 33947-33952 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T419 34035-34040 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T420 34073-34074 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T421 34146-34155 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T422 34230-34232 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T423 34230-34232 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T424 34289-34291 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T425 34446-34448 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T426 34449-34451 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T427 34452-34454 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T428 34490-34491 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T429 34605-34610 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T430 34641-34646 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T431 34697-34699 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T432 34736-34740 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T433 34959-34963 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T434 35050-35054 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T435 35069-35070 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T436 35172-35177 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T437 35258-35260 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T438 35298-35299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T439 35401-35406 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T440 35437-35442 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T441 35493-35495 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T442 35532-35536 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T443 35553-35558 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T444 35630-35635 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T445 36078-36080 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T446 36118-36119 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T447 36310-36328 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular component
T448 36330-36332 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T449 36469-36482 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T450 36833-36835 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T451 36921-36940 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T452 36981-36989 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T453 37006-37010 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T454 37082-37090 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T455 37106-37110 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T456 37260-37268 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T457 37282-37290 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T458 37308-37316 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T459 37521-37526 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T460 37550-37551 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T461 37698-37716 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular component
T462 37718-37720 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T463 37988-37989 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T464 38157-38158 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T465 38386-38390 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T466 38621-38623 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T467 38804-38810 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T468 39431-39435 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T469 39441-39449 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T470 39879-39884 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T471 40139-40148 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T472 40247-40249 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T473 40426-40432 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T474 40447-40460 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T475 40462-40478 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T476 40462-40478 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T477 40607-40612 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T478 40736-40738 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T479 40861-40870 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T480 40925-40934 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T481 40953-40962 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T482 41130-41139 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T483 41191-41200 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T484 41344-41346 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T485 41463-41472 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T486 41604-41613 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T487 41641-41646 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T488 41682-41691 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T489 41774-41775 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T490 41786-41788 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T491 41826-41830 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T492 41831-41835 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T493 41831-41835 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T494 41929-41938 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T495 41966-41975 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T496 42087-42092 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T497 42249-42254 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T498 42278-42279 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T499 42520-42525 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T500 42647-42649 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T501 42716-42717 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T502 43054-43055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T503 43282-43286 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T504 43650-43651 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T505 44051-44055 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T506 44066-44085 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T507 44520-44524 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T508 44752-44757 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T509 44799-44800 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T510 44958-44963 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T511 45041-45042 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T512 45116-45117 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T513 45397-45402 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T514 45407-45414 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T515 45508-45513 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T516 45624-45625 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T517 45754-45756 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T518 45950-45952 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T519 45982-45985 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T520 45986-45993 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T521 46064-46069 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T522 46130-46132 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T523 46133-46135 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T524 46136-46138 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T525 46195-46200 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T526 46219-46229 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T527 46240-46242 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T528 46240-46242 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T529 46244-46247 http://purl.obolibrary.org/obo/CLO_0050167 denotes LLC
T530 46248-46251 http://purl.obolibrary.org/obo/CLO_0050105 denotes PK1
T531 46253-46258 http://purl.obolibrary.org/obo/CLO_0050908 denotes PK-15
T532 46264-46270 http://purl.obolibrary.org/obo/CLO_0006963 denotes IPI-2I
T533 46271-46276 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T534 46457-46462 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T535 46652-46653 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T536 46713-46718 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T537 46894-46902 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T538 46918-46921 http://purl.obolibrary.org/obo/OGG_3000004893 denotes NS6
T539 46923-46926 http://purl.obolibrary.org/obo/CLO_0008201 denotes NS7
T540 47274-47276 http://purl.obolibrary.org/obo/CLO_0002861 denotes E3
T541 47337-47347 http://purl.obolibrary.org/obo/NCBITaxon_2759 denotes eukaryotic
T542 47348-47353 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T543 47440-47444 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T544 47534-47539 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T545 47675-47676 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T546 47819-47828 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T547 47855-47860 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T548 47889-47894 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T549 48237-48241 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T550 48282-48283 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T551 48393-48398 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T552 48403-48407 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T553 48428-48437 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T554 48428-48437 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T555 48438-48440 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T556 48542-48559 http://purl.obolibrary.org/obo/PR_000024990 denotes type I interferon
T557 48599-48602 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T558 48678-48691 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T559 48714-48718 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T560 49010-49012 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T561 49096-49100 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T562 49179-49181 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T563 49350-49358 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T564 49372-49380 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T565 49395-49403 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T566 49498-49499 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T567 49565-49566 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T568 49756-49769 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T569 49898-49904 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T570 50601-50610 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T571 50855-50864 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T572 51041-51044 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T573 51061-51067 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T574 51175-51188 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T575 51267-51283 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T576 51267-51283 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T577 51337-51339 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T578 51526-51535 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T579 51567-51568 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T580 51649-51651 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T581 51687-51696 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T582 51736-51749 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T583 52091-52104 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T584 52105-52114 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T585 52168-52176 http://purl.obolibrary.org/obo/CHEBI_3815 denotes collagen
T586 52244-52253 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T587 52300-52306 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T588 52321-52337 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T589 52321-52337 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T590 52393-52411 http://purl.obolibrary.org/obo/UBERON_0005769 denotes basement membranes
T591 52464-52468 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T592 52482-52499 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T593 52550-52551 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T594 52641-52650 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T595 52720-52729 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T596 52927-52935 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T597 52947-52956 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T598 53063-53071 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T599 53255-53258 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T600 53320-53325 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T601 53580-53589 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T602 53604-53613 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T603 53625-53630 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T604 53686-53687 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T605 53774-53783 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T606 53796-53805 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T607 53824-53829 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T608 53843-53844 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T609 53863-53868 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T610 53870-53880 http://purl.obolibrary.org/obo/CLO_0008447 denotes PK-15, was
T611 53870-53880 http://purl.obolibrary.org/obo/CLO_0008448 denotes PK-15, was
T612 53870-53875 http://purl.obolibrary.org/obo/CLO_0050908 denotes PK-15
T613 53954-53957 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T614 54126-54139 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T615 54219-54220 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T616 54279-54287 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T617 54384-54390 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T618 54406-54415 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T619 54462-54470 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T620 54512-54515 http://purl.obolibrary.org/obo/OGG_3000004893 denotes NS6
T621 54659-54668 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T622 54698-54707 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T623 54747-54756 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T624 54783-54788 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T625 54856-54865 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T626 54927-54928 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T627 55016-55025 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activated
T628 55112-55116 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T629 55169-55178 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T630 55334-55346 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T631 55381-55384 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T632 55502-55511 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T633 55678-55679 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T634 55701-55710 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T635 55870-55879 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T636 55963-55968 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T637 56023-56033 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T638 56060-56069 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T639 56139-56148 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T640 56170-56175 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T641 56215-56216 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T642 56292-56305 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T643 56306-56308 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T644 56323-56324 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T645 56335-56344 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T646 56627-56636 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T647 56951-56964 http://purl.obolibrary.org/obo/CLO_0053408 denotes AKT2 and cell
T648 56971-56980 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T649 57128-57137 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T650 57182-57187 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T651 57210-57219 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T652 57274-57279 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T653 57287-57291 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T654 57298-57307 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T655 57475-57479 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T656 57486-57495 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T657 57761-57771 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T658 57777-57780 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T659 57842-57846 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T660 57957-57958 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T661 58004-58014 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T662 58358-58361 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T663 58426-58433 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T664 58453-58454 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T665 58455-58460 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T666 58469-58474 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T667 58476-58481 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T668 58498-58503 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T669 58521-58526 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T670 58628-58629 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T671 58630-58635 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T672 58813-58818 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T673 58842-58847 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T674 58878-58883 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T675 59013-59018 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T676 59103-59108 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T677 59456-59459 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T678 59466-59467 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T679 59595-59599 http://purl.obolibrary.org/obo/CLO_0009989 denotes Huh7
T680 59600-59605 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T681 59684-59693 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T682 59854-59863 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T683 60013-60019 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T684 60013-60019 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T685 60013-60019 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T686 60013-60019 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T687 60020-60025 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T688 60277-60283 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T689 60486-60492 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T690 60486-60492 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T691 60486-60492 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T692 60486-60492 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T693 60493-60498 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T694 60625-60630 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T695 60667-60676 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T696 61005-61010 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T697 61017-61018 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T698 61082-61084 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T699 61085-61087 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T700 61088-61090 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T701 61092-61093 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T702 61219-61224 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T703 61282-61283 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T704 61363-61372 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T705 61391-61407 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T706 61391-61407 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T707 61409-61422 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T708 61424-61430 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T709 61501-61505 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T710 61512-61521 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T711 61765-61770 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T11 2760-2762 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T12 3431-3442 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T13 3431-3436 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T14 3437-3442 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T15 3533-3538 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T16 3673-3675 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T17 3676-3678 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T18 3679-3681 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T19 3972-3980 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T20 4550-4552 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T21 4553-4555 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T22 4556-4558 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T23 5430-5437 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T24 5468-5476 Chemical denotes selenium http://purl.obolibrary.org/obo/CHEBI_27568
T25 5523-5533 Chemical denotes penicillin http://purl.obolibrary.org/obo/CHEBI_17334|http://purl.obolibrary.org/obo/CHEBI_51356
T27 5548-5560 Chemical denotes streptomycin http://purl.obolibrary.org/obo/CHEBI_17076|http://purl.obolibrary.org/obo/CHEBI_58007
T29 5648-5651 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T30 5698-5700 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T33 5782-5789 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34 5943-5945 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T37 6072-6087 Chemical denotes Alexa Fluor 488 http://purl.obolibrary.org/obo/CHEBI_52661
T38 6078-6083 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T39 6260-6269 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T43 7198-7200 Chemical denotes NY http://purl.obolibrary.org/obo/CHEBI_73427
T44 7744-7747 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T45 7791-7798 Chemical denotes ethanol http://purl.obolibrary.org/obo/CHEBI_16236
T46 7980-7995 Chemical denotes Alexa Fluor 488 http://purl.obolibrary.org/obo/CHEBI_52661
T47 7986-7991 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T48 8226-8233 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T49 8502-8507 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T50 8703-8709 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T51 8752-8755 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T52 8761-8765 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T53 8770-8789 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T55 8779-8789 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T56 9022-9030 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T57 9053-9060 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58 9103-9110 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T59 9151-9153 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T61 9180-9188 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T62 9328-9330 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T63 9331-9333 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T64 9334-9336 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T65 9404-9411 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T66 9456-9464 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T67 9524-9530 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T68 9566-9570 Chemical denotes tris http://purl.obolibrary.org/obo/CHEBI_9754
T69 9572-9586 Chemical denotes 2-carboxyethyl http://purl.obolibrary.org/obo/CHEBI_50329
T70 9588-9597 Chemical denotes phosphine http://purl.obolibrary.org/obo/CHEBI_30278|http://purl.obolibrary.org/obo/CHEBI_35883
T72 9599-9603 Chemical denotes TCEP http://purl.obolibrary.org/obo/CHEBI_63213
T73 9623-9630 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T74 9760-9767 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T75 9768-9776 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T76 9868-9875 Chemical denotes acetone http://purl.obolibrary.org/obo/CHEBI_15347
T77 9893-9900 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T78 9901-9909 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T79 10116-10123 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T80 10233-10241 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T81 10334-10342 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T82 10375-10383 Chemical denotes reagents http://purl.obolibrary.org/obo/CHEBI_33893
T83 10773-10778 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T84 10929-10931 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T87 11058-11063 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T88 11116-11121 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T89 11212-11214 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T90 11215-11217 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T91 11218-11220 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T92 11230-11232 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T93 11233-11235 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T94 11236-11238 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T95 11263-11271 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T96 11472-11480 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T97 11547-11555 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T98 11682-11693 Chemical denotes formic acid http://purl.obolibrary.org/obo/CHEBI_30751
T99 11689-11693 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T100 11707-11719 Chemical denotes acetonitrile http://purl.obolibrary.org/obo/CHEBI_38472
T101 11758-11769 Chemical denotes formic acid http://purl.obolibrary.org/obo/CHEBI_30751
T102 11765-11769 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T103 11784-11796 Chemical denotes acetonitrile http://purl.obolibrary.org/obo/CHEBI_38472
T104 11813-11816 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T105 12051-12053 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T106 12058-12060 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T107 12061-12063 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T108 12072-12074 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T109 12205-12209 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T110 12224-12227 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T111 12266-12270 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T112 12351-12353 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T113 12354-12356 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T114 12441-12445 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T115 12572-12574 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T116 12602-12604 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T117 12605-12607 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T118 13261-13269 Chemical denotes cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T119 13367-13374 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T120 13655-13657 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T121 13698-13705 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T122 13710-13717 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T123 13824-13831 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T124 13836-13843 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T125 13986-13994 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T126 14052-14060 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T127 14493-14495 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T128 14518-14520 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T129 14547-14549 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T130 14771-14778 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T131 15476-15483 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T132 15484-15491 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T133 17114-17119 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T134 17616-17623 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T135 17704-17712 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T136 17802-17809 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T137 17840-17843 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T138 17883-17908 Chemical denotes poly(vinylidene fluoride) http://purl.obolibrary.org/obo/CHEBI_53250
T139 17888-17898 Chemical denotes vinylidene http://purl.obolibrary.org/obo/CHEBI_29854
T140 17899-17907 Chemical denotes fluoride http://purl.obolibrary.org/obo/CHEBI_17051
T141 17947-17949 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T144 18400-18407 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T145 18673-18675 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T146 18676-18678 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T147 18679-18681 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T148 19091-19093 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T149 19216-19218 Chemical denotes SD http://purl.obolibrary.org/obo/CHEBI_74807
T150 19321-19323 Chemical denotes La http://purl.obolibrary.org/obo/CHEBI_33336
T151 19723-19729 Chemical denotes formal http://purl.obolibrary.org/obo/CHEBI_48341
T152 20172-20180 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T153 21395-21397 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T154 21644-21651 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T155 22650-22665 Chemical denotes Alexa Fluor 488 http://purl.obolibrary.org/obo/CHEBI_52661
T156 22656-22661 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T157 22763-22769 Chemical denotes nuclei http://purl.obolibrary.org/obo/CHEBI_33252
T158 22795-22799 Chemical denotes DAPI http://purl.obolibrary.org/obo/CHEBI_51231
T159 23020-23022 Chemical denotes SD http://purl.obolibrary.org/obo/CHEBI_74807
T160 23203-23211 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T161 23338-23340 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T162 23341-23343 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T163 23344-23346 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T164 23380-23388 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T165 23601-23609 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T166 23648-23656 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T167 23792-23800 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T168 23829-23836 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T169 23844-23851 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T170 23862-23869 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T171 23906-23914 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T172 23947-23949 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T173 24368-24376 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T174 24645-24653 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T175 24725-24733 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T176 24886-24893 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T177 24956-24964 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T178 25021-25029 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T179 25159-25164 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T180 25165-25169 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T181 25201-25208 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T182 25358-25365 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T183 25374-25395 Chemical denotes S-adenosyl methionine http://purl.obolibrary.org/obo/CHEBI_15414
T184 25376-25384 Chemical denotes adenosyl http://purl.obolibrary.org/obo/CHEBI_33505
T185 25385-25395 Chemical denotes methionine http://purl.obolibrary.org/obo/CHEBI_16811|http://purl.obolibrary.org/obo/CHEBI_64558
T187 25414-25421 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T188 25507-25514 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T189 25725-25732 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T190 25792-25795 Chemical denotes GTP http://purl.obolibrary.org/obo/CHEBI_15996|http://purl.obolibrary.org/obo/CHEBI_37565
T192 25804-25811 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T193 25892-25902 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T194 25970-25984 Chemical denotes macromolecules http://purl.obolibrary.org/obo/CHEBI_33839
T195 26023-26027 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T196 26066-26069 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T197 26108-26111 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T198 26128-26135 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T199 26198-26201 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T200 26223-26231 Chemical denotes Collagen http://purl.obolibrary.org/obo/CHEBI_3815
T201 26237-26239 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T202 26240-26245 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T203 26346-26348 Chemical denotes T2 http://purl.obolibrary.org/obo/CHEBI_29298|http://purl.obolibrary.org/obo/CHEBI_75710
T205 26393-26395 Chemical denotes T2 http://purl.obolibrary.org/obo/CHEBI_29298|http://purl.obolibrary.org/obo/CHEBI_75710
T207 26673-26679 Chemical denotes amyrin http://purl.obolibrary.org/obo/CHEBI_10352
T208 26749-26756 Chemical denotes Calcium http://purl.obolibrary.org/obo/CHEBI_22984
T209 26797-26802 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T210 26954-26957 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T211 26996-27005 Chemical denotes Prolactin http://purl.obolibrary.org/obo/CHEBI_81580
T212 27173-27176 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T213 27292-27300 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T214 27330-27353 Chemical denotes low density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39026
T215 27342-27353 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T216 27543-27546 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T217 27629-27632 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T218 27762-27784 Chemical denotes Nucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_16862
T219 27762-27772 Chemical denotes Nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T220 27773-27784 Chemical denotes diphosphate http://purl.obolibrary.org/obo/CHEBI_18361|http://purl.obolibrary.org/obo/CHEBI_33019
T222 27846-27870 Chemical denotes nucleoside triphosphates http://purl.obolibrary.org/obo/CHEBI_17326
T223 27846-27856 Chemical denotes nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T224 27895-27899 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T226 28057-28064 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T227 28335-28337 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T228 28459-28461 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T229 28701-28708 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T230 28736-28739 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T233 28740-28746 Chemical denotes ribose http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013
T235 28800-28803 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T238 28804-28810 Chemical denotes ribose http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013
T240 28854-28861 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T241 28903-28917 Chemical denotes Protein serine http://purl.obolibrary.org/obo/CHEBI_8572
T242 28903-28910 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T243 28911-28917 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T244 28918-28927 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T245 29032-29039 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T246 29070-29077 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T247 29264-29271 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T248 29331-29344 Chemical denotes Ribosomal RNA http://purl.obolibrary.org/obo/CHEBI_18111
T249 29345-29352 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T250 29423-29430 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T251 29473-29481 Chemical denotes tyrosine http://purl.obolibrary.org/obo/CHEBI_18186
T252 29523-29537 Chemical denotes Protein serine http://purl.obolibrary.org/obo/CHEBI_8572
T253 29523-29530 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T254 29531-29537 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T255 29538-29547 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T256 29569-29572 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T259 29573-29579 Chemical denotes ribose http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013
T261 29689-29696 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T262 29760-29767 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T263 29768-29774 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T264 29775-29784 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T265 29845-29853 Chemical denotes Cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T266 29859-29882 Chemical denotes endopeptidase inhibitor http://purl.obolibrary.org/obo/CHEBI_82973
T267 29873-29882 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T268 29914-29935 Chemical denotes divalent metal cation http://purl.obolibrary.org/obo/CHEBI_60240
T269 29923-29935 Chemical denotes metal cation http://purl.obolibrary.org/obo/CHEBI_25213
T270 29929-29935 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T271 30014-30021 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T272 30022-30028 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T273 30029-30038 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T274 30078-30092 Chemical denotes Protein serine http://purl.obolibrary.org/obo/CHEBI_8572
T275 30078-30085 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T276 30086-30092 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T277 30093-30102 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T278 30142-30149 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T279 30202-30212 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T280 30202-30207 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T281 30208-30212 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T282 30229-30244 Chemical denotes complex protein http://purl.obolibrary.org/obo/CHEBI_33837
T283 30237-30244 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T284 30351-30358 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T285 30417-30440 Chemical denotes Endopeptidase inhibitor http://purl.obolibrary.org/obo/CHEBI_82973
T286 30431-30440 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T287 30462-30468 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T288 30469-30478 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T289 30479-30486 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T290 30555-30558 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T291 30588-30595 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T292 30764-30771 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T293 30835-30842 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T294 30959-30977 Chemical denotes small nuclear RNAs http://purl.obolibrary.org/obo/CHEBI_74035
T295 30979-30984 Chemical denotes snRNA http://purl.obolibrary.org/obo/CHEBI_74035
T296 31106-31133 Chemical denotes very long chain fatty acids http://purl.obolibrary.org/obo/CHEBI_27283
T297 31122-31133 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T298 31128-31133 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T299 31134-31141 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T300 31260-31267 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T301 31288-31295 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T302 31329-31336 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T303 31390-31397 Chemical denotes Calcium http://purl.obolibrary.org/obo/CHEBI_22984
T304 31398-31401 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T305 31522-31529 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T306 31623-31630 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T307 31737-31744 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T308 31780-31787 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T309 31822-31829 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T310 31973-31980 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T311 32031-32038 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T312 32092-32099 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T313 32141-32144 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T314 32152-32159 Chemical denotes Trypsin http://purl.obolibrary.org/obo/CHEBI_9765
T315 32212-32218 Chemical denotes Serine http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_17822
T317 32247-32258 Chemical denotes UDP-glucose http://purl.obolibrary.org/obo/CHEBI_18066
T318 32247-32250 Chemical denotes UDP http://purl.obolibrary.org/obo/CHEBI_17659|http://purl.obolibrary.org/obo/CHEBI_58223
T320 32251-32258 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167
T322 32259-32271 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T323 32326-32338 Chemical denotes Glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T324 32368-32396 Chemical denotes Phosphatidylglycerophosphate http://purl.obolibrary.org/obo/CHEBI_17264|http://purl.obolibrary.org/obo/CHEBI_37393
T326 32440-32447 Chemical denotes Calcium http://purl.obolibrary.org/obo/CHEBI_22984
T327 32448-32451 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T328 32518-32521 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T329 32796-32798 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T330 32799-32801 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T331 32802-32804 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T332 33193-33201 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T333 33384-33386 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T334 33536-33544 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T335 33898-33905 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T336 33986-33993 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T337 34230-34232 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T338 34289-34291 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T339 34446-34448 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T340 34449-34451 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T341 34452-34454 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T342 35258-35260 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T343 35381-35389 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T344 36078-36080 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T345 36243-36251 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T346 36305-36307 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T347 36330-36332 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T348 36359-36361 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T349 36375-36377 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T350 36392-36400 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T351 36686-36688 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T352 36833-36835 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T353 36850-36858 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T354 37144-37146 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T355 37161-37169 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T356 37251-37259 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T357 37296-37307 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T358 37490-37498 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T359 37606-37614 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T360 37620-37628 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T361 37693-37695 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T362 37718-37720 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T363 37747-37749 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T364 37891-37899 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T365 37942-37950 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T366 38052-38060 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T367 38547-38555 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T368 38655-38657 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T369 38674-38682 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T370 38735-38743 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T371 38778-38786 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T372 38838-38846 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T373 38868-38875 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T374 38936-38944 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T375 39025-39033 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T376 39090-39098 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T377 39156-39164 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T378 39186-39198 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T379 39231-39239 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T380 39312-39322 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T381 39349-39354 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T382 39471-39484 Chemical denotes inorganic ion http://purl.obolibrary.org/obo/CHEBI_36914
T383 39481-39484 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T384 39574-39582 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T385 39725-39733 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T386 39848-39856 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T387 40046-40054 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T388 40084-40091 Chemical denotes Pathway http://purl.obolibrary.org/obo/CHEBI_34922
T389 40374-40382 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T390 40736-40738 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T391 40761-40769 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T392 40827-40829 Chemical denotes 5B http://purl.obolibrary.org/obo/CHEBI_27560
T393 41032-41040 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T394 41252-41259 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T395 41297-41304 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T396 41347-41352 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T397 41673-41676 Chemical denotes AGE http://purl.obolibrary.org/obo/CHEBI_84123
T398 41735-41741 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
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T401 41844-41861 Chemical denotes glycosaminoglycan http://purl.obolibrary.org/obo/CHEBI_18085
T402 41876-41888 Chemical denotes progesterone http://purl.obolibrary.org/obo/CHEBI_17026
T403 42218-42226 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T404 42344-42352 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T405 42536-42538 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
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T407 42647-42649 Chemical denotes CP http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461
T409 42688-42696 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T410 42784-42792 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T411 42865-42873 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T412 42944-42952 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T413 43306-43313 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T414 43314-43321 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T415 43380-43387 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T416 43479-43486 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T417 43487-43494 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T418 43656-43663 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T419 43835-43843 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T420 44110-44118 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T421 44130-44138 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T422 44383-44391 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T423 44631-44639 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T424 44687-44694 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T425 44855-44862 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T426 44863-44870 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T427 44927-44935 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T428 45118-45125 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T429 45195-45203 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T430 45526-45534 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T431 45708-45717 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
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T433 46039-46046 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
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T435 46133-46135 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T436 46136-46138 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T437 46240-46242 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T438 46253-46255 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T439 46735-46743 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T440 46782-46790 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T441 46864-46872 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T442 46937-46945 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T443 47131-47138 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T444 47593-47601 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T445 47602-47610 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T446 47680-47698 Chemical denotes triphosphate group http://purl.obolibrary.org/obo/CHEBI_32959|http://purl.obolibrary.org/obo/CHEBI_68550
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T449 47693-47698 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T49184 48445-48453 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T98776 48549-48559 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T60756 48561-48564 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T58240 48576-48584 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T26062 48646-48648 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T23684 48736-48744 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T58411 48814-48816 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T90327 48918-48925 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T89594 48940-48951 Chemical denotes calcium ion http://purl.obolibrary.org/obo/CHEBI_39124
T8948 48940-48947 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T6312 48948-48951 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T60218 48960-48967 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T35294 49010-49012 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T54697 49051-49065 Chemical denotes apolipoprotein http://purl.obolibrary.org/obo/CHEBI_39015
T42534 49074-49081 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T52776 49139-49146 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T67126 49179-49181 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T25753 49258-49266 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T7958 49341-49349 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T63936 49430-49432 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T35836 49628-49636 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T69265 49786-49794 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T94431 49973-49981 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T70471 50138-50146 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T26 50361-50369 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T65075 50990-50998 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T28 51115-51123 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T95720 51224-51232 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T77842 51319-51327 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T31 51334-51336 Chemical denotes MT http://purl.obolibrary.org/obo/CHEBI_73614
T32 51415-51423 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T46428 51489-51496 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T55690 51569-51572 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T35 51585-51592 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T36 51623-51632 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T28170 51791-51803 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T10122 51799-51803 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T59838 51934-51943 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
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T41 52177-52182 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T42 52357-52364 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T84303 52994-52997 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T2647 53018-53021 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T3272 53022-53031 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T35749 53045-53048 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T79198 53108-53117 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T25165 53206-53214 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T75260 53342-53350 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T20380 53369-53372 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T14676 53576-53579 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T50278 53870-53872 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T42745 54106-54109 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T54 54504-54511 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38201 54540-54543 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T41383 54586-54605 Chemical denotes double-stranded RNA http://purl.obolibrary.org/obo/CHEBI_67208
T79790 55259-55264 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T7173 55277-55284 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T17429 57442-57450 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T60 57630-57644 Chemical denotes macromolecules http://purl.obolibrary.org/obo/CHEBI_33839
T4787 57865-57868 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T60517 58054-58056 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T62319 58157-58160 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T20667 58696-58698 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T59893 58898-58907 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T49991 59816-59825 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T37870 59826-59833 Chemical denotes MK-2206 http://purl.obolibrary.org/obo/CHEBI_67271
T94018 59826-59828 Chemical denotes MK http://purl.obolibrary.org/obo/CHEBI_74706
T27802 60165-60171 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T71 60188-60198 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T59320 60300-60310 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T47204 60312-60325 Chemical denotes cycloheximide http://purl.obolibrary.org/obo/CHEBI_27641
T76342 60330-60337 Chemical denotes emetine http://purl.obolibrary.org/obo/CHEBI_4781
T73678 60413-60428 Chemical denotes pharmaceuticals http://purl.obolibrary.org/obo/CHEBI_52217
T90954 60702-60711 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T83300 60817-60822 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T10537 60853-60862 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T18811 60962-60969 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T55089 61082-61084 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T81472 61085-61087 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T38162 61088-61090 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T21097 61137-61145 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T1741 61167-61175 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 671-679 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T3 687-695 Phenotype denotes vomiting http://purl.obolibrary.org/obo/HP_0002013
T4 697-708 Phenotype denotes dehydration http://purl.obolibrary.org/obo/HP_0001944
T5 1871-1879 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T6 4235-4240 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T7 4930-4938 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T8 27484-27500 Phenotype denotes Myeloid leukemia http://purl.obolibrary.org/obo/HP_0012324
T9 29124-29130 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T10 40997-41003 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T11 41756-41762 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T12 41820-41842 Phenotype denotes small cell lung cancer http://purl.obolibrary.org/obo/HP_0030357
T13 51373-51379 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T14 52598-52603 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T15 55461-55467 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T16 58285-58291 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T17 58293-58316 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T18 58504-58520 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T13 1265-1273 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T14 1265-1273 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T15 1265-1273 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T16 1265-1273 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T17 2914-2929 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T18 2952-2971 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T19 2959-2971 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T20 3165-3181 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T21 3232-3244 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T22 4075-4098 http://purl.obolibrary.org/obo/GO_0019048 denotes virus-host interactions
T23 4426-4438 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T24 5953-5981 http://purl.obolibrary.org/obo/GO_0004601 denotes Horseradish peroxidase (HRP)
T25 6831-6837 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T26 8246-8255 http://purl.obolibrary.org/obo/GO_0007586 denotes Digestion
T27 8697-8702 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T28 9355-9364 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T29 9518-9523 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T30 10208-10217 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T31 13297-13306 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T32 15793-15808 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T33 16184-16193 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T34 21756-21762 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T35 22840-22846 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T36 22918-22933 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T37 23167-23182 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T38 23879-23889 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T39 25250-25275 http://purl.obolibrary.org/obo/GO_0051607 denotes Defense response to virus
T40 25258-25275 http://purl.obolibrary.org/obo/GO_0009615 denotes response to virus
T41 25462-25487 http://purl.obolibrary.org/obo/GO_0051607 denotes Defense response to virus
T42 25470-25487 http://purl.obolibrary.org/obo/GO_0009615 denotes response to virus
T43 25586-25625 http://purl.obolibrary.org/obo/GO_0050688 denotes Regulation of defense response to virus
T44 25600-25625 http://purl.obolibrary.org/obo/GO_0051607 denotes defense response to virus
T45 25600-25616 http://purl.obolibrary.org/obo/GO_0006952 denotes defense response
T46 25864-25902 http://purl.obolibrary.org/obo/GO_0071357 denotes cellular response to type I interferon
T47 25873-25902 http://purl.obolibrary.org/obo/GO_0034340 denotes response to type I interferon
T48 25993-26013 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T49 25993-26006 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T50 26066-26107 http://purl.obolibrary.org/obo/GO_0003700 denotes DNA-binding transcription factor activity
T51 26078-26098 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T52 26078-26091 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T53 26108-26120 http://purl.obolibrary.org/obo/GO_0044349 denotes DNA excision
T54 26202-26222 http://purl.obolibrary.org/obo/GO_0140303 denotes translocase activity
T55 26444-26455 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T56 26498-26509 http://purl.obolibrary.org/obo/GO_0016791 denotes Phosphatase
T57 26572-26597 http://purl.obolibrary.org/obo/GO_0030100 denotes Regulation of endocytosis
T58 26586-26597 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T59 26877-26903 http://purl.obolibrary.org/obo/GO_0004896 denotes cytokine receptor activity
T60 26886-26903 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T61 26954-26995 http://purl.obolibrary.org/obo/GO_0003700 denotes DNA-binding transcription factor activity
T62 26966-26986 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T63 26966-26979 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T64 27065-27090 http://purl.obolibrary.org/obo/GO_0005096 denotes GTPase activator activity
T65 27203-27227 http://purl.obolibrary.org/obo/GO_0042073 denotes Intraflagellar transport
T66 27203-27227 http://purl.obolibrary.org/obo/GO_0035735 denotes Intraflagellar transport
T67 27218-27227 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T68 27405-27419 http://purl.obolibrary.org/obo/GO_0005319 denotes Apolipoprotein
T69 27569-27589 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T70 27569-27582 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T71 27730-27761 http://purl.obolibrary.org/obo/GO_0042981 denotes Regulation of apoptotic process
T72 27744-27761 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptotic process
T73 27833-27842 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T74 28057-28080 http://purl.obolibrary.org/obo/GO_0004672 denotes Protein kinase activity
T75 28065-28080 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T76 28212-28230 http://purl.obolibrary.org/obo/GO_0031497 denotes Chromatin assembly
T77 28366-28377 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T78 28519-28543 http://purl.obolibrary.org/obo/GO_0042073 denotes Intraflagellar transport
T79 28519-28543 http://purl.obolibrary.org/obo/GO_0035735 denotes Intraflagellar transport
T80 28534-28543 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T81 28581-28633 http://purl.obolibrary.org/obo/GO_0050680 denotes Negative regulation of epithelial cell proliferation
T82 28590-28633 http://purl.obolibrary.org/obo/GO_0050678 denotes regulation of epithelial cell proliferation
T83 28590-28600 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T84 28604-28633 http://purl.obolibrary.org/obo/GO_0050673 denotes epithelial cell proliferation
T85 28615-28633 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T86 28903-28943 http://purl.obolibrary.org/obo/GO_0004674 denotes Protein serine/threonine kinase activity
T87 28928-28943 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T88 28944-28952 http://purl.obolibrary.org/obo/GO_0051322 denotes Anaphase
T89 29022-29055 http://purl.obolibrary.org/obo/GO_0061630 denotes Ubiquitin protein ligase activity
T90 29022-29055 http://purl.obolibrary.org/obo/GO_0004842 denotes Ubiquitin protein ligase activity
T91 29417-29466 http://purl.obolibrary.org/obo/GO_0000179 denotes rRNA (adenine-N6,N6)-dimethyltransferase activity
T92 29523-29563 http://purl.obolibrary.org/obo/GO_0004674 denotes Protein serine/threonine kinase activity
T93 29548-29563 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T94 29652-29665 http://purl.obolibrary.org/obo/GO_0000209 denotes polyubiquitin
T95 29743-29749 http://purl.obolibrary.org/obo/GO_0016538 denotes Cyclin
T96 29760-29800 http://purl.obolibrary.org/obo/GO_0004674 denotes protein serine/threonine kinase activity
T97 29785-29800 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T98 29801-29809 http://purl.obolibrary.org/obo/GO_0004869 denotes Cystatin
T99 29845-29891 http://purl.obolibrary.org/obo/GO_0004869 denotes Cysteine-type endopeptidase inhibitor activity
T100 29859-29891 http://purl.obolibrary.org/obo/GO_0004866 denotes endopeptidase inhibitor activity
T101 29892-29898 http://purl.obolibrary.org/obo/GO_0016538 denotes Cyclin
T102 29929-29945 http://purl.obolibrary.org/obo/GO_0006812 denotes cation transport
T103 29936-29945 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T104 30078-30118 http://purl.obolibrary.org/obo/GO_0004674 denotes Protein serine/threonine kinase activity
T105 30103-30118 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T106 30192-30222 http://purl.obolibrary.org/obo/GO_0051957 denotes activity; amino acid transport
T107 30202-30222 http://purl.obolibrary.org/obo/GO_0006865 denotes amino acid transport
T108 30213-30222 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T109 30283-30306 http://purl.obolibrary.org/obo/GO_0010506 denotes Regulation of autophagy
T110 30297-30306 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T111 30297-30306 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T112 30308-30344 http://purl.obolibrary.org/obo/GO_0032008 denotes positive regulation of TOR signaling
T113 30317-30344 http://purl.obolibrary.org/obo/GO_0032006 denotes regulation of TOR signaling
T114 30317-30327 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T115 30331-30344 http://purl.obolibrary.org/obo/GO_0031929 denotes TOR signaling
T116 30335-30344 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T117 30417-30449 http://purl.obolibrary.org/obo/GO_0004866 denotes Endopeptidase inhibitor activity
T118 30534-30554 http://purl.obolibrary.org/obo/GO_0051347 denotes Transferase activity
T119 30721-30741 http://purl.obolibrary.org/obo/GO_0051347 denotes Transferase activity
T120 30996-31009 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T121 31060-31091 http://purl.obolibrary.org/obo/GO_0030036 denotes Actin cytoskeleton organization
T122 31066-31091 http://purl.obolibrary.org/obo/GO_0007010 denotes cytoskeleton organization
T123 31329-31346 http://purl.obolibrary.org/obo/GO_0015031 denotes Protein transport
T124 31337-31346 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T125 31463-31492 http://purl.obolibrary.org/obo/GO_0004784 denotes Superoxide dismutase activity
T126 31502-31521 http://purl.obolibrary.org/obo/GO_0042254 denotes ribosome biogenesis
T127 31603-31622 http://purl.obolibrary.org/obo/GO_0042254 denotes ribosome biogenesis
T128 31691-31701 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T129 31705-31762 http://purl.obolibrary.org/obo/GO_0043161 denotes proteasomal ubiquitin-dependent protein catabolic process
T130 31717-31762 http://purl.obolibrary.org/obo/GO_0006511 denotes ubiquitin-dependent protein catabolic process
T131 31737-31762 http://purl.obolibrary.org/obo/GO_0030163 denotes protein catabolic process
T132 31745-31762 http://purl.obolibrary.org/obo/GO_0009056 denotes catabolic process
T133 31926-31965 http://purl.obolibrary.org/obo/GO_0046921 denotes Alpha-(1→6)-fucosyltransferase activity
T134 31938-31965 http://purl.obolibrary.org/obo/GO_0008417 denotes fucosyltransferase activity
T135 32141-32151 http://purl.obolibrary.org/obo/GO_0006281 denotes DNA repair
T136 32212-32246 http://purl.obolibrary.org/obo/GO_0004252 denotes Serine-type endopeptidase activity
T137 32224-32246 http://purl.obolibrary.org/obo/GO_0004175 denotes endopeptidase activity
T138 32846-32859 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T139 36469-36490 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T140 36476-36490 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T141 36492-36512 http://purl.obolibrary.org/obo/GO_0022414 denotes reproductive process
T142 36514-36533 http://purl.obolibrary.org/obo/GO_0022610 denotes biological adhesion
T143 36535-36556 http://purl.obolibrary.org/obo/GO_0051704 denotes multiorganism process
T144 36558-36572 http://purl.obolibrary.org/obo/GO_0098754 denotes detoxification
T145 36574-36606 http://purl.obolibrary.org/obo/GO_0032501 denotes multicellular organismal process
T146 36608-36629 http://purl.obolibrary.org/obo/GO_0032502 denotes developmental process
T147 36631-36643 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T148 36725-36746 http://purl.obolibrary.org/obo/GO_0051704 denotes multiorganism process
T149 36748-36762 http://purl.obolibrary.org/obo/GO_0098754 denotes detoxification
T150 36768-36780 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T151 37260-37290 http://purl.obolibrary.org/obo/GO_0032411 denotes activity, transporter activity
T152 37260-37281 http://purl.obolibrary.org/obo/GO_0015291 denotes activity, transporter
T153 37296-37316 http://purl.obolibrary.org/obo/GO_0016209 denotes antioxidant activity
T154 38761-38774 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T155 38804-38823 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T156 38811-38823 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T157 38886-38916 http://purl.obolibrary.org/obo/GO_0043687 denotes posttranslational modification
T158 38960-38979 http://purl.obolibrary.org/obo/GO_0016192 denotes vesicular transport
T159 38970-38979 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T160 39012-39021 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T161 39055-39069 http://purl.obolibrary.org/obo/GO_0006396 denotes RNA processing
T162 39186-39208 http://purl.obolibrary.org/obo/GO_0008643 denotes carbohydrate transport
T163 39199-39208 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T164 39213-39223 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T165 39312-39332 http://purl.obolibrary.org/obo/GO_0006862 denotes nucleotide transport
T166 39323-39332 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T167 39337-39347 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T168 39349-39364 http://purl.obolibrary.org/obo/GO_0006869 denotes lipid transport
T169 39355-39364 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T170 39369-39379 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T171 39381-39392 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T172 39481-39494 http://purl.obolibrary.org/obo/GO_0006811 denotes ion transport
T173 39485-39494 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T174 39499-39509 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T175 40139-40157 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T176 40139-40148 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T177 40426-40445 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T178 40433-40445 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T179 40595-40605 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T180 40697-40715 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T181 40861-40879 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T182 40861-40870 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T183 40925-40942 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T184 40925-40934 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T185 40944-40948 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T186 40949-40962 http://purl.obolibrary.org/obo/GO_0043491 denotes AKT signaling
T187 40953-40962 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T188 40972-40983 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T189 41130-41148 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T190 41130-41139 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T191 41180-41184 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T192 41191-41209 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T193 41191-41200 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T194 41364-41376 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T195 41463-41481 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T196 41463-41472 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T197 41604-41621 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T198 41604-41613 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T199 41682-41699 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T200 41682-41691 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T201 41742-41752 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T202 41806-41818 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T203 41844-41874 http://purl.obolibrary.org/obo/GO_0006024 denotes glycosaminoglycan biosynthesis
T204 41862-41874 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T205 41898-41915 http://purl.obolibrary.org/obo/GO_0001556 denotes oocyte maturation
T206 41929-41946 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T207 41929-41938 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T208 41966-41984 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T209 41966-41975 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T210 42103-42113 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T211 42504-42514 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T212 42627-42645 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T213 42647-42649 http://purl.obolibrary.org/obo/GO_0009987 denotes CP
T214 43922-43937 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T215 44051-44061 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T216 44483-44487 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T217 44520-44530 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T218 44831-44843 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T219 45602-45617 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T220 45868-45884 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T221 47113-47126 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T222 47224-47232 http://purl.obolibrary.org/obo/GO_0051322 denotes anaphase
T223 47421-47432 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T224 47440-47461 http://purl.obolibrary.org/obo/GO_0051726 denotes cell cycle regulators
T225 47440-47450 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T226 47579-47592 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T227 47790-47813 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune responses
T228 48678-48699 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T229 48685-48699 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T230 48714-48735 http://purl.obolibrary.org/obo/GO_0051726 denotes cell cycle-regulating
T231 48714-48724 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T232 48850-48870 http://purl.obolibrary.org/obo/GO_0022414 denotes reproductive process
T233 49051-49065 http://purl.obolibrary.org/obo/GO_0005319 denotes apolipoprotein
T234 49096-49114 http://purl.obolibrary.org/obo/GO_1901987 denotes cell cycle control
T235 49096-49106 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T236 49350-49380 http://purl.obolibrary.org/obo/GO_0032411 denotes activity, transporter activity
T237 49350-49371 http://purl.obolibrary.org/obo/GO_0015291 denotes activity, transporter
T238 49756-49777 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T239 49763-49777 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T240 49898-49917 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T241 49905-49917 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T242 50240-50253 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T243 50601-50619 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T244 50601-50610 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T245 50855-50873 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T246 50855-50864 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T247 51061-51080 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T248 51068-51080 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T249 51137-51141 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T250 51353-51361 http://purl.obolibrary.org/obo/GO_0004869 denotes cystatin
T251 51424-51428 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T252 51526-51544 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T253 51526-51535 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T254 51633-51648 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T255 51687-51705 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T256 51687-51696 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T257 51886-51897 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T258 51997-52019 http://purl.obolibrary.org/obo/GO_0006413 denotes translation initiation
T259 51997-52008 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T260 52105-52123 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T261 52105-52114 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T262 52244-52262 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T263 52244-52253 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T264 52300-52319 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T265 52307-52319 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T266 52464-52478 http://purl.obolibrary.org/obo/GO_0035148 denotes tube formation
T267 52469-52478 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T268 52604-52616 http://purl.obolibrary.org/obo/GO_0001525 denotes angiogenesis
T269 52641-52659 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T270 52641-52650 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T271 52690-52694 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T272 52710-52719 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T273 52710-52719 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T274 52720-52738 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T275 52720-52729 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T276 52947-52965 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T277 52947-52956 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T278 53118-53131 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T279 53428-53444 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T280 53580-53598 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T281 53580-53589 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T282 53774-53791 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T283 53774-53783 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T284 54022-54037 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T285 54158-54173 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T286 54262-54287 http://purl.obolibrary.org/obo/GO_0004521 denotes endoribonuclease activity
T287 54419-54432 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T288 54453-54470 http://purl.obolibrary.org/obo/GO_0008233 denotes protease activity
T289 54659-54676 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T290 54659-54668 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T291 54698-54716 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T292 54698-54707 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T293 54718-54722 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T294 54819-54839 http://purl.obolibrary.org/obo/GO_0010506 denotes regulating autophagy
T295 54830-54839 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T296 54830-54839 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T297 54847-54851 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T298 54852-54865 http://purl.obolibrary.org/obo/GO_0043491 denotes AKT signaling
T299 54856-54865 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T300 55062-55080 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T301 55101-55110 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T302 55101-55110 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T303 55112-55122 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T304 55169-55186 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T305 55169-55178 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T306 55277-55294 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T307 55285-55294 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T308 55296-55319 http://purl.obolibrary.org/obo/GO_0010506 denotes regulation of autophagy
T309 55296-55306 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T310 55310-55319 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T311 55310-55319 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T312 55493-55497 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T313 55498-55511 http://purl.obolibrary.org/obo/GO_0043491 denotes AKT signaling
T314 55502-55511 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T315 55548-55577 http://purl.obolibrary.org/obo/GO_0010508 denotes positively regulate autophagy
T316 55559-55577 http://purl.obolibrary.org/obo/GO_0010506 denotes regulate autophagy
T317 55568-55577 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T318 55568-55577 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T319 55651-55660 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T320 55651-55660 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T321 55687-55691 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T322 55701-55718 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T323 55701-55710 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T324 55770-55801 http://purl.obolibrary.org/obo/GO_0010507 denotes negatively regulating autophagy
T325 55781-55801 http://purl.obolibrary.org/obo/GO_0010506 denotes regulating autophagy
T326 55792-55801 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T327 55792-55801 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T328 55852-55856 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T329 55870-55888 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T330 55870-55879 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T331 56046-56050 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T332 56060-56077 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T333 56060-56069 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T334 56149-56158 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T335 56149-56158 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T336 56279-56288 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T337 56279-56288 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T338 56412-56421 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T339 56412-56421 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T340 56475-56484 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T341 56475-56484 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T342 56488-56505 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T343 56488-56505 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T344 56574-56583 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T345 56574-56583 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T346 56613-56617 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T347 56627-56644 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T348 56627-56636 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T349 56738-56758 http://purl.obolibrary.org/obo/GO_0010506 denotes regulating autophagy
T350 56749-56758 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T351 56749-56758 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T352 56946-56950 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T353 56960-56970 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T354 56971-56989 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T355 56971-56980 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T356 57128-57146 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T357 57128-57137 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T358 57210-57228 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T359 57210-57219 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T360 57287-57297 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T361 57298-57315 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T362 57298-57307 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T363 57475-57485 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T364 57486-57503 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T365 57486-57495 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T366 57842-57860 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T367 57865-57875 http://purl.obolibrary.org/obo/GO_0006281 denotes DNA repair
T368 57896-57902 http://purl.obolibrary.org/obo/GO_0016538 denotes cyclin
T369 57925-57938 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T370 57988-58003 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T371 58157-58167 http://purl.obolibrary.org/obo/GO_0006281 denotes DNA repair
T372 58172-58181 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T373 58172-58181 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T374 58321-58338 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T375 58321-58338 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T376 58718-58737 http://purl.obolibrary.org/obo/GO_0019083 denotes viral transcription
T377 58724-58737 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T378 58784-58797 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T379 58949-58967 http://purl.obolibrary.org/obo/GO_0009299 denotes mRNA transcription
T380 58954-58967 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T381 59684-59702 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T382 59684-59693 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T383 59854-59871 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T384 59854-59863 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T385 60128-60139 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T386 60155-60163 http://purl.obolibrary.org/obo/GO_0045292 denotes splicing
T387 60172-60182 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T388 60188-60209 http://purl.obolibrary.org/obo/GO_0009117 denotes nucleotide metabolism
T389 60199-60209 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T390 60231-60246 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T391 60288-60299 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T392 60667-60685 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T393 60667-60676 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T394 60729-60754 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibit viral replication
T395 60737-60754 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T396 60737-60754 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T397 61363-61381 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T398 61363-61372 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T399 61424-61443 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T400 61431-61443 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T401 61476-61480 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T402 61486-61495 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T403 61486-61495 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T404 61501-61511 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T405 61512-61530 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T406 61512-61521 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T11 0-15 Sentence denotes 1 Introduction
T12 16-871 Sentence denotes Porcine deltacoronavirus (PDCoV) is enveloped and has a single-stranded, positive-sense RNA genome, which is classified in the genus Deltacoronavirus within the Coronaviridae family.1 Although PDCoV was initially identified in rectal swabs of pigs during a molecular epidemiological investigation conducted in Hong Kong, China in 2012,2 diarrheal diseases in pigs associated with PDCoV infection were first recorded in the U.S. in 2014.3 Since then, the virus has been detected in many other countries, including Canada, mainland China, South Korea, Thailand, Laos, Vietnam, Japan, Mexico, and so on.4,5 Clinically, PDCoV-infected pigs often present with diarrhea and/or vomiting, dehydration, and death of neonatal piglets.6 The outbreak of PDCoV infection in numerous countries has resulted in considerable economic losses to the global swine industry.7
T13 872-1644 Sentence denotes PDCoV has an obvious enteropathogenic characteristic in pigs.1,6 The small intestine of pigs, in particular the jejunum and ileum, are the primary target organs of PDCoV, and porcine small intestinal epithelial cells (IPEC) are the main sites of PDCoV replication in vivo.1,8,9 Histopathologic analyses showed that PDCoV infection not only causes villus atrophy and fall-off but also leads to necrosis of small intestinal enterocytes in infected pigs.1,6 Currently, an immortalized, nontumorigenic IPEC-J2 cell line, originally established using the jejunum of a newborn unsuckled piglet,10 has been shown to exhibit high similarities to porcine intestinal primary epithelial cells,11 and thus can better simulate the porcine physiological state than any other cell lines.
T14 1645-2059 Sentence denotes At present, IPEC-J2 cells have been successfully utilized as an ideal in vitro model system for investigating the interactions between epithelial cells and porcine enteric viruses, such as porcine rotavirus,12 porcine endemic diarrhea virus (PEDV),13 and transmissible gastroenteritis virus (TGEV).14 Recently, Jung and colleagues demonstrated that IPEC-J2 cells are quite susceptible to PDCoV infection in vitro.8
T15 2060-2336 Sentence denotes As a newly emerged swine enteropathogenic coronavirus, the pathogenic mechanisms of PDCoV are still poorly documented and warrant further exploration.1 It is well-known that when a virus invades a host cell, complex interactions between the host cell and the virus will occur.
T16 2337-3071 Sentence denotes On the one hand, the invading virus subverts some of the cellular biological functions in favor of the replication of the virus itself; on the other, the cells adopt various defense strategies to fight against the invading virus.15 The whole process of virus–cell interactions is usually accompanied by changes of genomics, transcriptomics, and proteomics.16 Recently, a systematic transcriptome analysis of PDCoV-infected PK-15 cells was conducted using high-throughput RNA sequencing, and 3762 differentially expressed genes were identified, most of which participate in the innate immunity and the corresponding signal transduction pathways.17 As of yet, however, no proteomic data are currently available for PDCoV-infected cells.
T17 3072-3988 Sentence denotes Proteomics is an effective tool for the comprehensive analysis of host cellular responses to viral infections, which is conducive to elucidating the underlying pathogenesis of the virus.18 The currently available proteomics techniques include two-dimensional gel electrophoresis,15 two-dimensional difference gel electrophoresis,19 stable isotope labeling by amino acids in cell culture,20,21 isobaric tags for relative and absolute quantitation (iTRAQ),22 and label-free proteomic techniques.23 Among all these mentioned techniques, iTRAQ coupled with liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis has shown several comparative advantages over its counterparts, for instance, high sensitivity, high throughput, high separating capacity, and high accuracy, and thus emerged as a robust quantitative proteomics technique for the comprehensive analysis of differentially expressed proteins (DEPs).
T18 3989-4439 Sentence denotes To date, this technique has been successfully applied to numerous studies involved in virus-host interactions, examples of which include TGEV,22 PEDV,24 foot-and-mouth disease virus (FMDV),25 porcine circovirus type 2 (PCV2), and classical swine fever virus (CSFV).26 These studies have given a good overview of the dynamic interactions between the virus and its host, and provide important clues for a better understanding of the viral pathogenesis.
T19 4440-4505 Sentence denotes For PDCoV, there has been no proteomic study on the virus so far.
T20 4506-4642 Sentence denotes In the present study, we coupled iTRAQ with LC-MS/MS to quantitatively analyze the DEPs of IPEC-J2 cells in response to PDCoV infection.
T21 4643-4731 Sentence denotes The identified DEPs were subsequently analyzed by comprehensive bioinformatics analyses.
T22 4733-4757 Sentence denotes 2 Materials and Methods
T23 4759-4792 Sentence denotes 2.1 Virus, Cells, and Antibodies
T24 4793-4841 Sentence denotes The PDCoV CHN-HN-1601 strain (GenBank access no.
T25 4842-4982 Sentence denotes MG832584) used in this study was isolated from the intestinal contents of a piglet with diarrhea using porcine kidney LLC-PK1 cells in 2017.
T26 4983-5112 Sentence denotes The eighth passage of PDCoV with a titer of 108.45 50% tissue culture infectious dose (TCID50)/mL was used for virus inoculation.
T27 5113-5243 Sentence denotes IPEC-J2 cells were generously provided by Prof. Yongchang Cao (School of Life Sciences, Sun Yat-Sen University, Guangzhou, China).
T28 5244-5602 Sentence denotes The cells were cultivated in Dulbecco’s Modified Eagle Medium/Ham’s F-12 (DMEM/F12) (Gibco, Carlsbad, CA, USA) containing 10% fetal bovine serum (FBS; Gibco, Carlsbad, CA, USA), 5 μg/mL insulin, 5 μg/mL transferrin, 5 ng/mL selenium (Sigma-Aldrich, St. Louis, MO, USA), 100 U/mL penicillin and 0.1 mg/mL streptomycin (Solarbio Life Sciences, Beijing, China).
T29 5603-5707 Sentence denotes Cells were cultured at 37 °C in a humidified CO2 incubator (Thermo Fisher Scientific, Waltham, MA, USA).
T30 5708-5821 Sentence denotes The monoclonal antibody (mAb), 1A3, raised against the PDCoV nucleocapsid protein was prepared in our laboratory.
T31 5822-5952 Sentence denotes Mouse anti-β-actin mAb, mouse anti-IFIT1 and rabbit anti-ANAPC7 polyclonal antibodies were bought from Abcam (Cambridge, MA, USA).
T32 5953-6071 Sentence denotes Horseradish peroxidase (HRP)-conjugated goat antimouse/rabbit immunoglobulin G (IgG) were obtained from Sigma-Aldrich.
T33 6072-6162 Sentence denotes Alexa Fluor 488-conjugated goat antimouse IgG was the product of Thermo Fisher Scientific.
T34 6164-6186 Sentence denotes 2.2 Virus Inoculation
T35 6187-6434 Sentence denotes IPEC-J2 cells approaching ∼80% confluence were washed twice with sterile phosphate buffered saline (PBS; 0.01 M, pH 7.4), and then mock infected or infected with PDCoV CHN-HN-1601 strain at a multiplicity of infection (MOI) of 0.1 TCID50 per cell.
T36 6435-6603 Sentence denotes After adsorption for 1.5 h at 37 °C, the cells were rinsed once with sterile PBS and serum-free DMEM/F12 medium containing 5 μg/mL of trypsin (Sigma-Aldrich) was added.
T37 6604-6717 Sentence denotes The cells were further cultured at 37 °C for the specified time points until different assays had been performed.
T38 6718-6911 Sentence denotes Viral propagation in IPEC-J2 cells was evaluated by observing cytopathic effect (CPE), determination of one-step growth curve and immunofluorescence assay (IFA) using the mAb 1A3 against PDCoV.
T39 6913-6930 Sentence denotes 2.3 TCID50 Assay
T40 6931-7065 Sentence denotes The kinetics of PDCoV multiplication in IPEC-J2 cells was determined by measuring the TCID50 using a microtitration infectivity assay.
T41 7066-7207 Sentence denotes Briefly, 100 μL/well of 10-fold serial dilutions of PDCoV were inoculated onto IPEC-J2 cells grown in 96-well microplates (Corning, NY, USA).
T42 7208-7355 Sentence denotes After adsorption at 37 °C for 1.5 h, the inocula were removed, and serum-free DMEM/F12 medium containing 5 μg/mL of trypsin was added to the wells.
T43 7356-7537 Sentence denotes After an additional 48-h cultivation, virus titers were measured by observing the presence of visible CPEs in the corresponding wells, and calculated using the Reed–Muench method.27
T44 7539-7547 Sentence denotes 2.4 IFA
T45 7548-7701 Sentence denotes When IPEC-J2 cells grown in 96-well microplates reached ∼80% confluence, they were mock infected or infected with PDCoV at an MOI of 0.1 TCID50 per cell.
T46 7702-7830 Sentence denotes After a 48-h cultivation at 37 °C with 5% CO2, the cells were fixed with prechilled 100% ethanol for 15 min at room temperature.
T47 7831-7929 Sentence denotes After washing with PBS, the cells were probed with the mAb 1A3 (1:5000 dilution) at 37 °C for 1 h.
T48 7930-8107 Sentence denotes Following another washing step, 1000-fold-diluted Alexa Fluor 488-conjugated goat antimouse IgG (Thermo Fisher Scientific) was added to the cells and incubated at 37 °C for 1 h.
T49 8108-8219 Sentence denotes After washing thrice with PBS, cells were observed with an Eclipse Ci-S microscope (Nikon Corp., Tokyo, Japan).
T50 8221-8275 Sentence denotes 2.5 Protein Extraction, Digestion, and iTRAQ Labeling
T51 8276-8480 Sentence denotes At 24 h postinfection (hpi), both PDCoV- and mock-infected IPEC-J2 cells grown in T25 flasks (∼5 × 106 cells/flask) were rinsed twice with prechilled PBS, and then harvested with disposable cell scrapers.
T52 8481-8591 Sentence denotes Three flasks of each group (PDCoV or mock) were harvested and used as three independent biological replicates.
T53 8592-8801 Sentence denotes After centrifugation at 300g for 10 min, the cell pellets from each flask were lysed with 800 μL of RIPA lysis buffer (Beyotime, Shanghai, China) containing 1% SDS, 8 M urea and protease inhibitors (Beyotime).
T54 8802-8907 Sentence denotes The cell lysates were further sonicated on ice for 5 min with 10 s bursts and 10 s pauses between cycles.
T55 8908-9031 Sentence denotes After centrifugation for 20 min at 12 000g and 4 °C, the supernatant was collected and used as the total cellular proteins.
T56 9032-9160 Sentence denotes The concentration of protein samples was determined using a Pierce BCA protein assay kit (Thermo Scientific, Rockford, IL, USA).
T57 9161-9342 Sentence denotes The total cellular proteins from each biological replicate were equally divided into three aliquots, which were used as three independent technical replicates for the LC-MS/MS runs.
T58 9343-9531 Sentence denotes For tryptic digestion and iTRAQ labeling, an aliquot of each protein sample containing ∼100 μg of total cellular proteins was adjusted to a 100-μL final volume using the RIPA lysis buffer.
T59 9532-9681 Sentence denotes A final concentration of 10 mM of tris (2-carboxyethyl) phosphine (TCEP) was added to each protein sample, which was then incubated at 37 °C for 1 h.
T60 9682-9842 Sentence denotes Afterward, iodoacetamide was added at a final concentration of 40 mM, and the protein solution was incubated for 40 min at room temperature shielded from light.
T61 9843-9963 Sentence denotes Subsequently, prechilled acetone was added to the protein solution in a ratio of 6:1 and precipitated at −20 °C for 4 h.
T62 9964-10101 Sentence denotes After centrifugation (10 000g, 4 °C) for 20 min, the precipitate was dissolved with 100 μL of 100 mM triethylammonium bicarbonate (TEAB).
T63 10102-10189 Sentence denotes The processed protein samples were digested with 2 μg/μL of trypsin overnight at 37 °C.
T64 10190-10320 Sentence denotes Following tryptic digestion, the generated peptides were dried by vacuum centrifugation, and redissolved with 20 μL of 0.5 M TEAB.
T65 10321-10463 Sentence denotes The prepared peptides were then labeled with an iTRAQ reagents-8 plex kit (AB Sciex, Foster City, CA, USA) as per the manufacturer’s protocol.
T66 10464-10740 Sentence denotes Briefly, the three independent biological replicates of mock-infected cellular samples were each labeled with iTRAQ-113, iTRAQ-114, and iTRAQ-115; the three independent biological replicates of PDCoV-infected samples were each labeled with iTRAQ-116, iTRAQ-119, and iTRAQ-121.
T67 10741-11016 Sentence denotes All the labeled samples of each group were mixed with an equal amount, and then fractionated using an ACQUITY ultra performance liquid chromatography (UPLC) system (Waters Corp., Milford, MA, USA) combined with an ACQUITY UPLC BEH C18 column (300 Å, 1.7 μm, 2.1 mm × 150 mm).
T68 11017-11079 Sentence denotes Finally, a total of 10 fractions of each group were collected.
T69 11080-11205 Sentence denotes After merging two fractions of each group into one, the pooled 10 fractions were dried by using a rotary vacuum concentrator.
T70 11207-11229 Sentence denotes 2.6 LC-MS/MS Analysis
T71 11230-11437 Sentence denotes LC-MS/MS analyses of the labeled peptides were carried out using a Q-Exactive mass spectrometer (Thermo Fisher Scientific, San Jose, CA, USA) combined with an EASY-nLC 1200 system (Thermo Fisher Scientific).
T72 11438-11798 Sentence denotes After loading 2 μg of the labeled peptides onto a C18 reversed phase HPLC column (Thermo Fisher Scientific), peptides were chromatographed for 120 min at a flow rate of 300 nL/min over gradients from 2–80% (mobile phase A comprising 0.1% (v/v) formic acid and 2% (v/v) acetonitrile; mobile phase B comprising 0.1% (v/v) formic acid and 80% (v/v) acetonitrile).
T73 11799-11940 Sentence denotes The following ion source parameters, including spray voltage 1.8 kV, capillary temperature 275 °C and declustering potential 100 V, were set.
T74 11941-12064 Sentence denotes The mass spectrometer was run using a data-dependent Top-20 acquisition mode, switching automatically between MS and MS/MS.
T75 12065-12251 Sentence denotes A full MS scan ranging from 350 to 1300 m/z was conducted at 70 000 resolution with an automatic gain control (AGC) target value of 3 × 106 ions and a maximum ion transfer (IT) of 20 ms.
T76 12252-12565 Sentence denotes The precursor ions were fragmented by means of high-energy collisional dissociation (HCD), and all MS/MS spectra were scanned using the following parameters: resolution 17 500; AGC 1 × 105 ions; maximum IT 50 ms; dynamic exclusion duration 18 s; normalized collision energy 30%; and intensity threshold 1.6 × 105.
T77 12567-12588 Sentence denotes 2.7 MS Data Analysis
T78 12589-12720 Sentence denotes The original MS/MS raw data were analyzed using the Proteome Discoverer Software 2.1 (Thermo Fisher Scientific, San Jose, CA, USA).
T79 12721-12890 Sentence denotes The data were searched against the database of UniProt Sus scrofa (February 26, 2017, containing 26 103 sequences, http://www.uniprot.org/proteomes/UP000008227, version:
T80 12891-13108 Sentence denotes Uniprot-proteome-UP000008227-Sus scrofa (Pig)-26103s-20170226.fasta) and porcine deltacoronavirus Uniprot database (February 26, 2017, containing 442 sequences, http://www.uniprot.org/porcinedeltacoronavirus, version:
T81 13109-13173 Sentence denotes Uniprot-Porcine deltacoronavirus [1586324]-442s-20170226.fasta).
T82 13174-13621 Sentence denotes The parameters for database searching were set as follows: instrument, TripleTOF 5600; cysteine alkylation, iodoacetamide; digestion, trypsin; dynamic modification, oxidation (M), acetylation (protein N-terminus), and iTRAQ8plex (Y); static modification, iTRAQ8plex (K), iTRAQ8plex (N-terminus), and carbamidomethyl (C); maximum missed cleavages, 2; precursor mass tolerance, 10 ppm; fragment mass tolerance, 0.05 Da; validation based on, q-value.
T83 13622-13860 Sentence denotes To guarantee the accuracy of the MS data analysis, the cutoff value for the peptide and protein confidences was set to >95% and >1.20, respectively, coupled with a false discovery rate (FDR) of ≤1% for peptide and protein identifications.
T84 13861-14226 Sentence denotes The t test function in the R language software was applied to calculate the p-value of the expression difference of cellular proteins between mock- and PDCoV-infected IPEC-J2 cells, and only proteins with a fold change >1.20 or <0.83 and a p-value < 0.05, which have being widely used as the criteria for judging DEPs,28,29 were considered differentially expressed.
T85 14228-14256 Sentence denotes 2.8 Bioinformatics Analysis
T86 14257-14551 Sentence denotes The data for the identified DEPs of PDCoV-infected IPEC-J2 cells were submitted to Gene Ontology (GO) Terms (http://geneontology.org/) for GO analysis, by which the DEPs were assigned into three branches of ontology—biological process (BP), cellular component (CC), and molecular function (MF).
T87 14552-14766 Sentence denotes GO enrichment analysis for the DEPs was done using the Goatools software (https://github.com/tanghaibao/GOatools) with Fisher’s exact test, and those with a p-value < 0.05 were thought to be significantly enriched.
T88 14767-14928 Sentence denotes The protein database of clusters of Orthologous Groups (COG; http://www.ncbi.nlm.nih.gov/COG/) was also used to assign possible functions to the identified DEPs.
T89 14929-15235 Sentence denotes The Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) pathway analyses were performed to reveal the potential functions of the DEPs, which were annotated using the BlastP program of the Diamond software against the KEGG database with a cutoff E-value ≤ 1 × 10–5 and identity ≥0.98.
T90 15236-15706 Sentence denotes The pathway enrichment statistics were performed using the KOBAS software (http://kobas.cbi.pku.edu.cn/home.do/) with the Fisher’s exact test, and those with p-values < 0.05 were regarded as statistically significant.30,31 Furthermore, the protein–protein interaction networks were created using the online STRING database (http://string-db.org/) and visualized by Cytoscape (https://cytoscape.org/), which was widely used for analyzing the relationships between DEPs.32
T91 15708-15746 Sentence denotes 2.9 Quantitative Real-Time PCR (qPCR)
T92 15747-15927 Sentence denotes To verify the DEPs identified by iTRAQ at the transcriptional level, the mRNA of two representative DEPs, the downregulated ANAPC7 and the upregulated IFIT1, were detected by qPCR.
T93 15928-16079 Sentence denotes Total cellular RNA of both PDCoV- and mock-infected IPEC-J2 cells was extracted using the TaKaRa MiniBEST universal RNA extraction kit (Dalian, China).
T94 16080-16260 Sentence denotes The first strand cDNA was synthesized using 2 μg of cellular RNA and with a RevertAid First Strand cDNA Synthesis Kit (Thermo Scientific) following the manufacturer’s instructions.
T95 16261-16409 Sentence denotes The qPCR assays were conducted using a TaKaRa SYBR Premix Ex Taq kit on an ABI 7500 real-time PCR machine along with β-actin as a housekeeping gene.
T96 16410-16614 Sentence denotes The primers used for the qPCR assay were designed based on the NCBI reference sequences for ANAPC7, IFIT1 and β-actin genes under GenBank accession numbers NM_016238, HQ679904 and NM_001101, respectively.
T97 16615-16690 Sentence denotes The information for the designed primers was as following: ANAPC7 (Forward:
T98 16691-16727 Sentence denotes 5′-CTTTGCTGAGGAACGCACTG-3′, Reverse:
T99 16728-16772 Sentence denotes 5′-TCCATGTCGTCCACATCCTC-3′); IFIT1 (Forward:
T100 16773-16814 Sentence denotes 5′-GAAGATTTAACCCAACAAGAACATA-3′, Reverse:
T101 16815-16866 Sentence denotes 5′-CTTTCGATACGTAAGGTAATACAGC-3′); β-actin (Forward:
T102 16867-16903 Sentence denotes 5′-TCCCTGGAGAAGAGCTACGA-3′, Reverse:
T103 16904-16932 Sentence denotes 5′-AGCACTGTGTTGGCGTACAG-3′).
T104 16933-17142 Sentence denotes The qPCR assays were carried out in a 20-μL reaction volume comprised 10 μL of TaKaRa SYBR Premix Ex Taq, 0.4 μL of each forward and reverse primer (10 μM), 7.2 μL of nuclease-free water, and 2 μL of template.
T105 17143-17379 Sentence denotes The qPCR amplifications were carried out using a thermal profile with an initial step at 95 °C for 2 min, followed by 40 cycles of 95 °C for 10 s, 60 °C for 10 s (for ANAPC7 and β-actin) or 55 °C for 10 s (for IFIT1) and 72 °C for 40 s.
T106 17380-17491 Sentence denotes Fold-change values were calculated in term of the 2–ΔΔCt method and normalized to the β-actin reference gene.33
T107 17493-17520 Sentence denotes 2.10 Western Blot Analysis
T108 17521-17679 Sentence denotes To further validate the identified DEPs, Western blot was performed to detect ANAPC7 and IFIT1 protein expression levels using β-actin as an internal control.
T109 17680-17787 Sentence denotes Briefly, total cellular proteins were extracted from both mock- and PDCoV-infected IPEC-J2 cells at 24 hpi.
T110 17788-18031 Sentence denotes The resulting protein samples were separated on 12% SDS-PAGE gels and transferred onto 0.22 μm poly(vinylidene fluoride) (PVDF) membranes (Millipore, Bedford, MA, USA) using a semidry electrophoretic transfer cell (Bio-Rad, Hercules, CA, USA).
T111 18032-18239 Sentence denotes The membranes were blocked with 5% (w/v) nonfat dry milk overnight at 4 °C and then probed with either anti-ANAPC7 (1:1000), anti-IFIT1 (1:1000), or anti-β-actin (1:5000) primary antibodies at 37 °C for 1 h.
T112 18240-18388 Sentence denotes After thorough washing with PBST, the membranes were incubated with the corresponding HRP-conjugated secondary antibodies (1:8000) for 1 h at 37 °C.
T113 18389-18615 Sentence denotes The target protein blots on the membranes were developed with an enhanced chemiluminescence detection kit (Thermo Fisher Scientific), and images were taken using a ProteinSimple FluorChem E image system (Santa Clara, CA, USA).
T114 18617-18640 Sentence denotes 2.11 Data Availability
T115 18641-18899 Sentence denotes The proteomics data obtained by LC-MS/MS in this study were deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) by means of the Proteomics Identifications (PRIDE) partner repository with the data set identifier PXD019975.
T116 18901-18927 Sentence denotes 2.12 Statistical Analysis
T117 18928-19127 Sentence denotes The methods used for the statistical analysis of proteomic data and the corresponding threshold criteria were described in detail in the corresponding sections of MS data and bioinformatics analyses.
T118 19128-19340 Sentence denotes The data from three independent qPCR runs were expressed as means ± standard deviation (SD), and were statistically analyzed by Student’s t test using the GraphPad Prism software (Version 5.0; La Jolla, CA, USA).
T119 19341-19419 Sentence denotes Differences with a value of p < 0.05 were regarded as statistically different.
T120 19421-19431 Sentence denotes 3 Results
T121 19433-19493 Sentence denotes 3.1 Determination of the Optimal Inoculation Dose for PDCoV
T122 19494-19741 Sentence denotes To obtain the optimal inoculation dose that could produce DEPs to the greatest extent, IPEC-J2 cells were inoculated with PDCoV at low, medium, and high MOIs (i.e., 0.01, 0.1, and 1 TCID50/cell, respectively) for 36 h before the formal experiment.
T123 19742-19922 Sentence denotes By observing the CPE, we found that the high MOI resulted in a rapid synchronous infection of all the cells, causing majority of the cells detached and disintegrated within 12 hpi.
T124 19923-19996 Sentence denotes This is not conducive to the interaction between the virus and the cells.
T125 19997-20181 Sentence denotes By contrast, the cells inoculated with the low MOI only displayed minimal CPEs at the same time points, which might induce limited changes in the expression levels of diverse proteins.
T126 20182-20300 Sentence denotes Therefore, the medium MOI of 0.1 was selected as the optimal dose for PDCoV inoculation in all subsequent experiments.
T127 20302-20395 Sentence denotes 3.2 Selection of the Best Sampling Time for the Proteomic Analysis Following PDCoV Infection
T128 20396-20618 Sentence denotes In order to determine the optimal time point for the proteomic analysis following PDCoV infection, IPEC-J2 cells were inoculated with PDCoV at an MOI of 0.1 and microscopically observed for CPE at 4, 8, 12, 24, and 36 hpi.
T129 20619-20764 Sentence denotes Meanwhile, the cell supernatants at the same time points were collected and used to measure the proliferation dynamics of PDCoV in IPEC-J2 cells.
T130 20765-20945 Sentence denotes Compared to mock-infected cells, PDCoV-inoculated IPEC-J2 cells began to exhibit slight CPE at 8 hpi, and the CPE gradually became increasingly evident as the infection progressed.
T131 20946-21263 Sentence denotes Obvious CPEs were observed at 12 hpi and became more evident at 24 and 36 hpi, which were characterized by cell rounding, enlarging, and granular degeneration of the cytoplasm that occurred either singly or in different-sized clusters, usually forming cell masses, followed by cell shrinkage and increased detachment.
T132 21264-21529 Sentence denotes These CPEs were in agreement with those reported by Jung et al.,8 and resembled those observed in PDCoV-infected swine testicular (ST) and LLC-PK1 cells.34 However, from 36 hpi onward, the majority of the cells became detached and floated in the medium (Figure 1A).
T133 21530-21742 Sentence denotes The proliferation of PDCoV in IPEC-J2 cells was verified by IFA using a mAb raised against the PDCoV nucleocapsid protein, and the results demonstrated that almost all cells became infected at 24 hpi (Figure 1B).
T134 21743-21913 Sentence denotes The one-step growth curve further revealed that the virus titer reached a plateau of ∼107.5 TCID50/mL at 24 hpi, followed by a gradual and continuous decline (Figure 1C).
T135 21914-22267 Sentence denotes In general, the time point at which viral proliferation stays high but no obvious cellular membrane or cytoskeleton rearrangement occurs is the optimal sampling time for a proteomic analysis.22 On the basis of the above experimental results, we therefore chose 24 hpi as the optimal time point for the proteomic analysis of PDCoV-infected IPEC-J2 cells.
T136 22268-22494 Sentence denotes Figure 1 Proliferation of PDCoV in IPEC-J2 cells. (A) Morphological changes in IPEC-J2 cells infected with the PDCoV CHN-HN-1601 strain at an MOI of 0.1 TCID50/cell or mocked infected for 4, 8, 12, 24, and 36 h, respectively.
T137 22495-22757 Sentence denotes Scale bars, 10 μm. (B) Confirmation of PDCoV proliferation in IPEC-J2 cells by immunofluorescence assays using the mAb 1A3 specific for PDCoV (α-N) and an Alexa Fluor 488-labeled goat antimouse IgG, and mock-infected cells at 24 h was used as a negative control.
T138 22758-22807 Sentence denotes Cell nuclei were counterstained with DAPI (blue).
T139 22808-22934 Sentence denotes Scale bars, 10 μm. (C) One-step growth curve of PDCoV in IPEC-J2 cells at the indicated time points following viral infection.
T140 22935-23058 Sentence denotes The titer of virus was presented as TCID50/mL, and the data were recorded as means ± SD from three independent experiments.
T141 23060-23135 Sentence denotes 3.3 Identification of DEPs of IPEC-J2 Cells in Response to PDCoV Infection
T142 23136-23357 Sentence denotes To identify the DEPs following viral infection, the total cellular proteins extracted from PDCoV- and mock-infected IPEC-J2 cells were processed for quantitative proteomics research using iTRAQ-coupled LC-MS/MS technique.
T143 23358-23486 Sentence denotes In all, 5502 cellular proteins were identified in both PDCoV- and mock-infected IPEC-J2 cells at 24 hpi (Supplementary File S1).
T144 23487-23770 Sentence denotes On the basis of the widely used criteria for judging DEPs (fold changes >1.2 or <0.83 and with p < 0.05),28,29 23 proteins were significantly upregulated and 55 proteins were markedly downregulated in PDCoV-infected IPEC-J2 cells in comparison with the mock-infected cells (Table 1).
T145 23771-24072 Sentence denotes Meanwhile, six viral proteins, including the nucleocapsid protein, spike protein, membrane protein, 3C-like proteinase Nsp5, accessory proteins NS6 and NS7 (Supplementary File S2), were also identified in PDCoV-infected IPEC-J2 cells by searching against the porcine deltacoronavirus Uniprot database.
T146 24073-24299 Sentence denotes In order to ensure the reliability of the obtained proteomic data, three biological replicates of PDCoV- or mock-infected cell samples were collected and three technical replicates were performed during the proteomic analysis.
T147 24300-24465 Sentence denotes The difference was plotted against the percentage of the identified proteins, which suggested that the proteomic data had high credibility (Supplementary Figure S1).
T148 24466-24682 Sentence denotes Notably, due to the fact that the current genome database of pigs is inadequately annotated in comparison to the human genome database, we found six uncharacterized or unassigned proteins among the 78 DEPs (Table 1).
T149 24683-24765 Sentence denotes Therefore, a functional analysis of these proteins warrants further investigation.
T150 24766-24885 Sentence denotes Table 1 Differentially Expressed Proteins Identified by iTRAQ Analysis of IPEC-J2 Cells in Response to PDCoV Infection
T151 24886-25008 Sentence denotes protein name Uniprot accession no. log2 ratios (infection/control) peptides sequence coverage (%) p-values functions
T152 25009-25053 Sentence denotes Upregulated proteins in PDCoV-infected cells
T153 25054-25178 Sentence denotes ISG15 ubiqutin-like modifier I3LU39 1.24 18 30.1 3.62 × 10–06 RIG-1/MDA5 mediated induction of IFN-alpha/beta pathways
T154 25179-25275 Sentence denotes Interferon-stimulated protein 60 F1SCY2 1.09 5 14.6 3.51 × 10–05 Defense response to virus
T155 25276-25365 Sentence denotes 2′-5′ oligoadenylates synthetase 1, OAS1 F1RJN6 0.81 2 3.1 0.0001 Antiviral protein
T156 25366-25487 Sentence denotes Radical S-adenosyl methionine domain-containing protein 2 F1S9L2 0.70 6 13.8 1.60 × 10–05 Defense response to virus
T157 25488-25625 Sentence denotes Interferon induced protein with tetratricopeptide repeats 1, IFIT1 K7GN56 0.70 5 9.6 0.0002 Regulation of defense response to virus
T158 25626-25708 Sentence denotes Family with sequence similarity 8 member A1 F1RUH9 0.69 1 2.2 0.0103 unknown
T159 25709-25772 Sentence denotes uncharacterized protein I3LH89 0.658 1 4.7 0.0074 unknown
T160 25773-25902 Sentence denotes Interferon-induced GTP-binding protein Mx1 K7GKN2 0.58 2 2.0 0.0013 GTPase activity; cellular response to type I interferon
T161 25903-25984 Sentence denotes Nucleoporin 37 (NUP37) F1SRJ4 0.57 1 5.2 0.0016 Transporting macromolecules
T162 25985-26107 Sentence denotes Nuclear transcription factor Y submit beta (NFYB) F1SG36 0.55 2 6.3 0.0013 DNA-binding transcription factor activity
T163 26108-26222 Sentence denotes DNA excision repair protein ERCC-6-like isoform a (ERCC6L) I3LFY4 0.45 1 0.8 0.0496 DNA translocase activity
T164 26223-26333 Sentence denotes Collagen type IV alpha 1 chain F1RLM1 0.45 1 0.6 0.0153 Component of glomerular basement membranes (GBM)
T165 26334-26404 Sentence denotes Ribouclease T2 F1SBX8 0.35 2 4.4 0.0004 Ribinuclease T2 activity
T166 26405-26455 Sentence denotes MRPL32 I3LTC4 0.34 1 11.7 0.0472 translation
T167 26456-26517 Sentence denotes Phostensin Q767M0 0.32 3 6.8 0.0047 Phosphatase binding
T168 26518-26597 Sentence denotes Bridging integrator 1 F1RXZ6 0.32 7 22.7 0.0012 Regulation of endocytosis
T169 26598-26697 Sentence denotes Terpene cyclase/mutase family member I3L7C2 0.29 10 16.7 0.0012 Beta-amyrin synthase activity
T170 26698-26764 Sentence denotes Secretagogin (SCGN) Q06A97 0.28 2 9.4 0.0214 Calcium binding
T171 26765-26903 Sentence denotes Interleukin 13 receptor subunit alpha 2 K7GSC6 0.28 2 14.6 0.0370 Obsolete signal transducer activity and cytokine receptor activity
T172 26904-26995 Sentence denotes FOS-like 1 (FOSL1) F1RU26 0.28 1 6.2 0.0214 DNA-binding transcription factor activity
T173 26996-27090 Sentence denotes Prolactin regulatory element binding F1SED4 0.27 9 10.1 0.0229 GTPase activator activity
T174 27091-27202 Sentence denotes CDK-activating kinase assembly factor MAT1 (MNAT1) F6Q8T7 0.27 1 6.4 0.0076 DNA-dependent ATPase activity
T175 27203-27277 Sentence denotes Intraflagellar transport 81 F1RNN4 0.26 1 3.7 0.0033 Tubulin binding
T176 27278-27324 Sentence denotes Downregulated proteins in PDCoV-infected cells
T177 27325-27427 Sentence denotes Very low density lipoprotein receptor (VLDLR) E7CXS1 –0.27 21 22.8 0.0001 Apolipoprotein binding
T178 27428-27483 Sentence denotes uncharacterized I3LFU8 –0.27 3 5.6 0.0218 unknown
T179 27484-27554 Sentence denotes Myeloid leukemia factor 2 F1SLT1 –0.28 6 15.8 0.0488 DNA-binding
T180 27555-27658 Sentence denotes Helicase-like transcription factor (HLTF) I3LM88 –0.28 1 1.9 0.0254 DNA-dependent ATPase activity
T181 27659-27761 Sentence denotes Ras association domain family member 6 F1RUL8 –0.29 2 5.5 0.0011 Regulation of apoptotic process
T182 27762-27870 Sentence denotes Nucleoside diphosphate kinase 7 (NME7) F1RPV8 –0.29 3 8.0 0.0279 Synthesis of nucleoside triphosphates
T183 27871-28002 Sentence denotes Bromodomain adjacent to zinc finger domain 2A (BAZ2A) F1SLA2 –0.29 1 1.2 0.0189 Component of the nucleolar remodeling complex
T184 28003-28080 Sentence denotes BMP2 inducible kinase I3LT15 –0.29 1 2.8 0.0319 Protein kinase activity
T185 28081-28152 Sentence denotes RNA helicase (DDX55) F1RFL5 –0.29 1 1.5 0.0274 Catalytic activity
T186 28153-28211 Sentence denotes TMEM55B F1S8H7 –0.29 1 3.9 0.0445 Catalytic activity
T187 28212-28319 Sentence denotes Chromatin assembly factor 1 subunit A (CHAF1A) F1S7L7 –0.29 4 5.3 0.0252 Chromo shadow domain binding
T188 28320-28461 Sentence denotes RNA polymerase II subunit A C-terminal domain phosphatase (CTDP1) F1RWS7 –0.29 2 5.5 0.0123 Promoting the activity of RNA polymerase II
T189 28462-28518 Sentence denotes uncharacterized I3LIB8 –0.30 2 14.7 0.0373 unknown
T190 28519-28633 Sentence denotes Intraflagellar transport 172 I3LPC6 –0.30 1 0.69 0.0383 Negative regulation of epithelial cell proliferation
T191 28634-28730 Sentence denotes Myocyte enhancer factor 2D (MEF2D) F1RP31 –0.30 1 1.9 0.0418 Protein dimerization activity
T192 28731-28835 Sentence denotes Poly(ADP-ribose) glycohydrolase F1SDW4 –0.31 1 1.3 0.0355 Poly(ADP-ribose) glycohydrolase activity
T193 28836-28943 Sentence denotes Mitogen-activated protein kinase 4 F1STG5 –0.31 4 4.9 0.0233 Protein serine/threonine kinase activity
T194 28944-29055 Sentence denotes Anaphase promoting complex subunit 7 (ANAPC7) I3L7Q8 –0.31 4 7.9 0.0218 Ubiquitin protein ligase activity
T195 29056-29152 Sentence denotes Transmembrane protein 45A F1SKZ6 –0.31 1 3.6 0.0191 Modulates cancer cell chemosensitivity
T196 29153-29242 Sentence denotes Katanin p60 ATPase-containing subunit A1 I3LVP8 –0.32 2 32.1 0.0181 ATPase activity
T197 29243-29330 Sentence denotes Ubiquitin associated protein 2 (UBAP2) F1SEA5 –0.32 1 1.7 0.0237 Cadherin binding
T198 29331-29466 Sentence denotes Ribosomal RNA adenine dimethylase domain containing 1 F1RHJ0 –0.32 1 2.3 0.0391 rRNA (adenine-N6,N6)-dimethyltransferase activity
T199 29467-29563 Sentence denotes Lemur tyrosine kinase 2 F1RFL2 –0.32 1 1.0 0.0104 Protein serine/threonine kinase activity
T200 29564-29704 Sentence denotes Poly(ADP-ribose) polymerase family member 10 F1RSK9 –0.32 1 1.8 0.0182 K63-linked polyubiquitin modification-dependent protein binding
T201 29705-29800 Sentence denotes CDK9 C9E1C9 –0.32 4 11.0 0.0183 Cyclin-dependent protein serine/threonine kinase activity
T202 29801-29891 Sentence denotes Cystatin C Q0Z8R0 –0.33 2 17.1 0.0282 Cysteine-type endopeptidase inhibitor activity
T203 29892-30013 Sentence denotes Cyclin and CBS domain divalent metal cation transport mediator 2 F1S849 –0.33 1 1.1 0.0173 Adenylnucleotide binding
T204 30014-30118 Sentence denotes Protein-serine/threonine kinase F1S069 –0.34 4 8.2 0.0247 Protein serine/threonine kinase activity
T205 30119-30222 Sentence denotes Aamy domain-containing protein F1S5K2 –0.34 1 2.5 0.0390 Catalytic activity; amino acid transport
T206 30223-30344 Sentence denotes GATOR complex protein WDR24 I3LF05 –0.34 1 1.4 0.0368 Regulation of autophagy; positive regulation of TOR signaling
T207 30345-30449 Sentence denotes CD109 antigen isoform 1 preproprotein K7GKY0 –0.35 18 12.9 0.0105 Endopeptidase inhibitor activity
T208 30450-30554 Sentence denotes Nonspecific serine/threonine protein kinase (AKT2) G9BWQ2 –0.35 7 12.0 0.0310 Transferase activity
T209 30555-30651 Sentence denotes DNA polymerase delta interacting protein 3 (POLDIP3) F1SJQ4 –0.35 3 3.8 0.0287 RNA binding
T210 30652-30741 Sentence denotes Exostosin-like glycosyltransferase 2 F1S568 –0.35 1 3.3 0.0215 Transferase activity
T211 30742-30873 Sentence denotes 4F5 domain-containing protein I3LS25 –0.36 9 42.4 0.0015 Positive regulator of amyloid protein aggregation and proteotoxicity
T212 30874-31009 Sentence denotes Integrator complex subunit 4 (INTS4) F1STY6 –0.37 3 2.4 0.0429 Involved in the small nuclear RNAs (snRNA) U1 and U2 transcription
T213 31010-31091 Sentence denotes Smoothelin-like 2 F1RGN8 –0.37 1 2.7 0.0119 Actin cytoskeleton organization
T214 31092-31193 Sentence denotes Elongation of very long chain fatty acids protein I3L7S8 –0.39 1 21.6 0.0444 Catalytic activity
T215 31194-31249 Sentence denotes uncharacterized I3LBD1 –0.40 1 7.4 0.0085 unknown
T216 31250-31346 Sentence denotes Secretory carrier-associated membrane protein F1SJ46 –0.41 7 13.1 0.0144 Protein transport
T217 31347-31409 Sentence denotes Cadherin 6 F1SP42 –0.42 3 3.7 0.0122 Calcium ion binding
T218 31410-31492 Sentence denotes Superoxide dismutase I3LUD1 –0.43 2 4.9 0.0139 Superoxide dismutase activity
T219 31493-31622 Sentence denotes Probable ribosome biogenesis protein C16orf42 homologue (SMARCA2) F1RFZ6 –0.44 1 4.4 0.0470 Involved in ribosome biogenesis
T220 31623-31762 Sentence denotes Protein zyg-11 homologue B F1S6I1 –0.45 1 3.4 0.0030 Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
T221 31763-31855 Sentence denotes BCL2 interacting protein 3 I3LDJ9 –0.45 2 6.6 0.0009 Protein homodimerization activity
T222 31856-31965 Sentence denotes Alpha-(1,6)-fucosyltransferase (FUT8) F1SA54 –0.47 1 3.3 0.0492 Alpha-(1→6)-fucosyltransferase activity
T223 31966-32064 Sentence denotes Signal peptide peptidase-like 2B F1S8G9 –0.52 2 1.9 0.0190 Protein homodimerization activity
T224 32065-32151 Sentence denotes INTS3 and NABP interacting protein (INTS4) F1SNA6 –0.54 5 12.5 0.0006 DNA repair
T225 32152-32246 Sentence denotes Trypsin domain containing 1 F1SUE6 –0.55 1 1.8 0.0215 Serine-type endopeptidase activity
T226 32247-32367 Sentence denotes UDP-glucose glycoprotein glucosyltransferase 2 F1RP50 –0.62 2 2.3 0.0320 Glycoprotein glucosyltransferase activity
T227 32368-32459 Sentence denotes Phosphatidylglycerophosphate synthase 1 I3LN95 –0.62 1 2.7 0.0440 Calcium ion binding
T228 32460-32529 Sentence denotes Metallothionein-2A P79379 –0.63 9 32.8 0.0017 Metal ion binding
T229 32530-32585 Sentence denotes uncharacterized I3LNY1 –0.66 1 6.5 0.0246 unknown
T230 32586-32650 Sentence denotes Formin-like 1 I3LH80 –0.83 1 1.8 0.0191 Rho GTPase binding
T231 32651-32707 Sentence denotes uncharacterized K7GL96 –1.13 1 10.9 0.0412 unknown
T232 32709-32770 Sentence denotes 3.4 Validation of the DEPs by qPCR and Western Blot Analyses
T233 32771-32949 Sentence denotes To validate the obtained LC-MS/MS data, qPCR was performed to evaluate the transcription levels of two randomly selected DEPs, the downregulated ANAPC7 and the upregulated IFIT1.
T234 32950-33036 Sentence denotes To this end, IPEC-J2 cells were mock-infected or infected with PDCoV at an MOI of 0.1.
T235 33037-33125 Sentence denotes At 24 hpi, total cellular RNA was extracted from the cells and subjected to qPCR assays.
T236 33126-33339 Sentence denotes As shown in Figure 2A, the level of mRNA encoding ANAPC7 and IFIT1 proteins was significantly downregulated and upregulated in PDCoV-infected cells, respectively, as compared to the mock-infected cells (p < 0.05).
T237 33340-33446 Sentence denotes The qPCR results were in agreement with the MS data which were acquired by the iTRAQ approach (Figure 2B).
T238 33447-33666 Sentence denotes For further confirmation of the proteomic data, the expression level of ANAPC7 and IFIT1 proteins in IPEC-J2 cells, which were infected exactly as the aforementioned conditions, was also tested by Western blot analysis.
T239 33667-33772 Sentence denotes To track the progression of PDCoV infection, the mAb 1A3 that specifically recognizes PDCoV was utilized.
T240 33773-34106 Sentence denotes As shown in Figure 2C, compared with the mock-infected IPEC-J2 cells, PDCoV significantly decreased the expression of ANAPC7 protein and its relative ratio to β-actin in the cells, whereas the expression of IFIT1 protein and its relative ratio to β-actin in the cells were significantly increased as a consequence of PDCoV infection.
T241 34107-34233 Sentence denotes The original images of the entire PVDF membranes containing the target Western blots were included in Supplementary Figure S2.
T242 34234-34309 Sentence denotes The Western blot results were also consistent with the MS data (Figure 2D).
T243 34310-34417 Sentence denotes Taken together, these experimental results reveal that our quantitative proteomics data are quite reliable.
T244 34418-34632 Sentence denotes Figure 2 Validation of the LC-MS/MS results by Western blot analysis. (A) Quantitative real-time PCR (qPCR) analysis of the relative mRNA expression level of ANAPC7 and IFIT1 in IPEC-J2 cells upon PDCoV infection.
T245 34633-34765 Sentence denotes IPEC-J2 cells were mock infected or infected with the PDCoV CHN-HN-1601 strain at an MOI of 0.1 TCID50/cell and collected at 24 hpi.
T246 34766-34861 Sentence denotes Total RNA was extracted and reverse-transcribed into cDNA for the subsequent analysis via qPCR.
T247 34862-34964 Sentence denotes Fold-change values were calculated based on the 2–ΔΔCt method, using β-actin as the housekeeping gene.
T248 34965-35216 Sentence denotes Error bars indicate the standard error of three independent experiments (Student’s t test; *p < 0.05). (B) The relative ratio of ANAPC7 and IFIT1 mRNAs normalized to β-actin between PDCoV- and mock-infected cells was calculated based on the qPCR data.
T249 35217-35428 Sentence denotes The iTRAQ ratio (PDCoV/Mock) obtained by MS analysis was simultaneously shown as a comparison. (C) Western blot (WB) analysis of the expression of ANAPC7 and IFIT1 proteins in IPEC-J2 cells upon PDCoV infection.
T250 35429-35537 Sentence denotes IPEC-J2 cells were mock infected or infected with the PDCoV CHN-HN-1601 strain at an MOI of 0.1 TCID50/cell.
T251 35538-35757 Sentence denotes At 24 hpi, the cells were harvested and processed for WB analysis using rabbit anti-ANAPC7, mouse anti-IFIT1 polyclonal antibodies and the mAb 1A3 specific for PDCoV. β-Actin was included as an internal loading control.
T252 35758-36036 Sentence denotes The images shown are representatives of three independent experiments. (D) The optical intensity ratio between the corresponding bands (PDCoV-infected band/Mock band) was measured by densitometric scanning and normalized to the intensity of the β-actin bands in each experiment.
T253 36037-36131 Sentence denotes The iTRAQ ratio (PDCoV/Mock) obtained by MS analysis was simultaneously shown as a comparison.
T254 36133-36174 Sentence denotes 3.5 GO Functional Annotation of the DEPs
T255 36175-36363 Sentence denotes To characterize the DEPs, GO analysis was conducted to annotate the proteins based on three major categories: biological process (BP), cellular component (CC), and molecular function (MF).
T256 36364-37419 Sentence denotes Within the BP category, the proteins were predicted to be involved in 13 biological processes, including immune system process, reproductive process, biological adhesion, multiorganism process, detoxification, multicellular organismal process, developmental process, localization, and so on (Figure 3A; Supplementary File S3), among which those associated with multiorganism process, detoxification, and localization were significantly enriched (Figure 3B); within the CC category, the proteins were predicted to be primarily distributed within 9 different cellular components, such as synapse, extracellular region, membrane, organelle, and cell part (Figure 3A), with the significantly enriched being located in the membrane, organelle and cell part (Figure 3B); and within the MF category, the proteins were predicted to be linked with 8 molecular functions, for instance, structural molecule activity, transporter activity, and antioxidant activity (Figure 3A), but no GO term was identified as significantly enriched within this category (Figure 3B).
T257 37420-37615 Sentence denotes Figure 3 GO functional annotation of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection. (A) GO annotations for the upregulated and downregulated proteins.
T258 37616-37751 Sentence denotes The proteins were annotated into three major categories: biological process (BP), cellular component (CC), and molecular function (MF).
T259 37752-37820 Sentence denotes The abscissa text indicates the name and classification of GO terms.
T260 37821-38061 Sentence denotes The pink and blue columns represent the upregulated and downregulated proteins, respectively, with the number of altered proteins being marked on top of each column. (B) GO enrichment analysis for the upregulated and downregulated proteins.
T261 38062-38136 Sentence denotes The name and classification of each GO term are indicated in the abscissa.
T262 38137-38228 Sentence denotes Each column denotes a GO term, and the height of the column represents the enrichment rate.
T263 38229-38403 Sentence denotes The color implies the significance of the enrichment (p-value), and the darker the color, the more significant the enrichment of the GO term (Fisher’s exact test; *p < 0.05).
T264 38405-38449 Sentence denotes 3.6 COG Function Classification of the DEPs
T265 38450-38556 Sentence denotes To further characterize the DEPs, COG function classification was also applied to categorize the proteins.
T266 38557-38659 Sentence denotes As shown in Figure 4, the DEPs could be further classified into 18 categories (Supplementary File S4).
T267 38660-39224 Sentence denotes Among them, 9 proteins were related to general function prediction only; 8 proteins were involved in transcription; 6 proteins were relevant to signal transduction mechanisms; 5 proteins were associated with protein turnover, posttranslational modification, and chaperones; 4 proteins were linked to vesicular transport, intracellular trafficking, and secretion; 4 proteins were correlated with RNA processing and modification; 3 proteins were correlated with chromatin structure and dynamics; 3 proteins were associated with carbohydrate transport and metabolism.
T268 39225-39554 Sentence denotes Seven proteins were respectively related to one of the following biological functions: nucleotide transport and metabolism; lipid transport and metabolism; translation, ribosomal structure, and biogenesis; cell wall/membrane/envelope biogenesis; inorganic ion transport and metabolism; extracellular structures; and cytoskeleton.
T269 39555-39643 Sentence denotes Notably, another 7 proteins related to unknown function were also identified (Figure 4).
T270 39644-39774 Sentence denotes Therefore, further investigation concentrating on the function of these cellular proteins is certainly worth trying in the future.
T271 39775-39906 Sentence denotes Figure 4 COG function classification of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection.
T272 39907-40072 Sentence denotes The capital letters in abscissa denote the COG categories as marked on the right of the histogram and the ordinate indicates the number of proteins in each category.
T273 40074-40112 Sentence denotes 3.7 KEGG Pathway Analysis of the DEPs
T274 40113-40491 Sentence denotes To explore the underlying signaling pathways existing among the identified DEPs, KEGG pathway analyses were done to draw pathway maps.35 As shown in Figure 5A, the 78 identified DEPs were involved in 26 pathways, among which the top 5 involving more than three proteins were related to viral infectious diseases, signal transduction, immune system, digestive system and cancers.
T275 40492-40740 Sentence denotes All the DEPs could be further classified into 6 KEGG pathway categories, including organismal systems, metabolism, human diseases, genetic information processing, environmental information processing, and cellular processes (Supplementary File S5).
T276 40741-40856 Sentence denotes For the upregulated proteins, the top 20 relevant pathways were illustrated in Figure 5B and Supplementary File S6.
T277 40857-41009 Sentence denotes The signaling pathways of interest included the RIG-I-like receptor signaling pathway, PI3K-AKT signaling pathway, endocytosis, pathways in cancer, etc.
T278 41010-41125 Sentence denotes For the downregulated proteins, the top 20 relevant pathways were displayed in Figure 5C and Supplementary File S7.
T279 41126-41220 Sentence denotes The signaling pathways of interest included the mTOR, MAPK, FoxO signaling pathways and so on.
T280 41221-41377 Sentence denotes Interestingly, one upregulated protein (Secretagogin) and one downregulated protein (AKT2) were simultaneously involved in Fc gamma R-mediated phagocytosis.
T281 41378-41530 Sentence denotes To further explore the possible involvement of the identified DEPs in the underlying signaling pathways, KEGG pathway enrichment analysis was performed.
T282 41531-41959 Sentence denotes Our data demonstrated that the DEPs were primarily involved in the HIF-1 signaling pathway, HTLV-I infection, human papillomavirus infection, AGE-RAGE signaling pathway in diabetic complications, central carbon metabolism in cancer, influenza A, measles, Fc gamma R-mediated phagocytosis, small cell lung cancer, glycosaminoglycan biosynthesis, progesterone-mediated oocyte maturation, and relaxin signaling pathway (Figure 5D).
T283 41960-42150 Sentence denotes These signaling pathways were mainly distributed in four distinct functional categories: environmental information processing, human diseases, metabolism, and organismal systems (Figure 5D).
T284 42151-42353 Sentence denotes Figure 5 KEGG pathway analysis of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection. (A) KEGG pathway classification of the 78 differentially expressed proteins.
T285 42354-42651 Sentence denotes The ordinate text indicates the name of biological functions which were classified into 6 KEGG pathway categories, including organismal systems (OS), metabolism (M), human diseases (HD), genetic information processing (GIP), environmental information processing (EIP), and cellular processes (CP).
T286 42652-42953 Sentence denotes The abscissa displays the number of proteins in each category. (B) The top 20 significant pathways of the significantly upregulated proteins. (C) The top 20 significant pathways of the significantly downregulated proteins. (D) KEGG pathway enrichment analysis of the differentially expressed proteins.
T287 42954-43030 Sentence denotes The abscissa text displays the name and classification of the KEGG pathways.
T288 43031-43122 Sentence denotes Each column represents a pathway, and the height of the column implies the enrichment rate.
T289 43123-43299 Sentence denotes The color manifests the significance of the enrichment (p-value), and the darker the color, the more significant the enrichment of the pathway (Fisher’s exact test; *p < 0.05).
T290 43301-43354 Sentence denotes 3.8 Protein–Protein Interaction Networks of the DEPs
T291 43355-43516 Sentence denotes To explore the potential protein network connections between the identified DEPs, the web-tool STRING was applied to depict protein–protein interaction networks.
T292 43517-43737 Sentence denotes As shown in Figure 6, the DEPs were mapped to three major functional interaction networks, among which two were tightly connected by a hub protein, ENSSSCG00000000860 (namely NUP37), while the third exists independently.
T293 43738-44086 Sentence denotes For the two tightly connected networks, they were comprised of two groups of strongly interacted proteins, including SCGN-ISG15-OAS1-IFIT1-IFIT3-ANAPC7-NME7, which are associated with innate immunity, and POLDIP3-NUP37-ERCC6L-DDX55-SMARCA2-NFRB-BAZ2A-HLTF-CHAF1A-CDK9-MNAT1-CTDP1-INTS4, which are associated with cell cycle and cellular components.
T294 44087-44229 Sentence denotes Of note, at least five proteins act as hub proteins in these two networks tightly connected, including IFIT1, IFIT3, NUP37, SMARCA2, and CDK9.
T295 44230-44343 Sentence denotes Interestingly, MNAT1 interacted highly with CTDP1 and CDK9, and INTS4 was also well connected to CDK9 (Figure 6).
T296 44344-44544 Sentence denotes For the third network, there were five proteins with strong interaction in response to PDCoV infection, including MEF2D, VLDLR, LOC780439, PDK1, and AKT2, which are related to cell death and survival.
T297 44545-44844 Sentence denotes Taken together, these findings further indicate that various functional types of host proteins, various biological functions, and complicated protein networks were affected during PDCoV infection of IPEC-J2 cells, which should provide valuable clues for a better understanding of PDCoV pathogenesis.
T298 44845-44985 Sentence denotes Figure 6 Protein–protein interaction networks of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection.
T299 44986-45097 Sentence denotes The networks were built using the STRING database with a minimum interaction score of 0.4 at medium confidence.
T300 45098-45266 Sentence denotes Each node denotes a protein in the graph; each line is indicative of the interaction between two proteins, and the thicker the line, the closer the mutual relationship.
T301 45267-45351 Sentence denotes The width of the edges represents the predicted strength of functional associations.
T302 45353-45366 Sentence denotes 4 Discussion
T303 45367-46094 Sentence denotes The interactions between host cells and viruses are highly complex, which usually involves numerous alterations in the expression of diverse genes, mRNAs, and proteins.36,37 Deciphering the laws behind these changes over the course of viral infection plays a vital role in elucidating the pathogenic mechanisms and in developing efficacious antiviral strategies.37 Over the past decade, MS-based proteomic techniques have contributed significantly to uncovering more factors and mechanisms related to viral infections and the corresponding host cellular pathophysiological processes.18 However, no research to date has focused on differential proteomic analysis of global protein profiles in host cells upon infection by PDCoV.
T304 46095-46201 Sentence denotes In this study, iTRAQ combined with LC-MS/MS was used to identify the DEPs in PDCoV-infected IPEC-J2 cells.
T305 46202-46639 Sentence denotes Although various cell lines including ST, LLC-PK1, PK-15, and IPI-2I cells have been shown to be highly permissive to PDCoV infection,17,34,38 considering porcine enterocytes are the natural targets for PDCoV infection in vivo,8,9 we chose to use IPEC-J2 cells for the proteomic analysis with the goal of obtaining experimental data that could better reflect the physiological state of pigs and the true state of PDCoV infection in vivo.
T306 46640-46824 Sentence denotes Ultimately, a total of 78 DEPs were identified in PDCoV-infected IPEC-J2 cells, among which 23 proteins were significantly upregulated and 55 proteins were significantly downregulated.
T307 46825-46946 Sentence denotes Moreover, we also identified six viral proteins including the spike, membrane, nucleocapsid, NS6, NS7, and Nsp5 proteins.
T308 46947-47171 Sentence denotes To ensure the reliability of the DEPs identified in the present study, we used qPCR and Western blot to validate two randomly selected DEPs, ANAPC7 and IFIT1, at the transcription and protein expression levels, respectively.
T309 47172-47566 Sentence denotes In brief, ANAPC7 is an important constituent of the anaphase promoting complex/cyclosome, which is an E3 ubiquitin ligase that regulates the temporal progression of eukaryotic cells by mediating ubiquitination and subsequent 26S proteasome-mediated degradation of key cell cycle regulators.39 The downregulation of ANAPC7 is indicative of dysfunction of IPEC-J2 cells caused by PDCoV infection.
T310 47567-47895 Sentence denotes IFIT1 is an innate immune effector molecule that can directly recognize viral single-stranded RNAs carrying a 5′-triphosphate group, thereby inhibiting the expression of viral mRNA.40 The upregulation of IFIT1 reveals that innate immune responses were activated in PDCoV-infected IPEC-J2 cells to combat with the invading virus.
T311 47896-48067 Sentence denotes Through the validation of these two DEPs, we found that the obtained proteomics data were reliable and valid, and thus suitable for the subsequent bioinformatics analysis.
T312 48068-48180 Sentence denotes First, we made an attempt to assign possible functions to the 78 identified DEPs using GO functional annotation.
T313 48181-48536 Sentence denotes This tool is an internationally standardized system for gene function classification, which provides a dynamic, updated, controlled vocabularies or ontologies and can well interpret the characteristics of target genes and gene products in various organisms.41 The proteins of our interest involving in different biological functions are listed as follows.
T314 48537-48700 Sentence denotes Five type I interferon (IFN)-inducible proteins, ISG15, OAS1, Mx1, IFIT1, and IFIT3, were clustered into the BP category associated with the immune system process.
T315 48701-48871 Sentence denotes Another five cell cycle-regulating proteins, ERCC6L, NME7, NFYB, FOSL1, and CTDP1, were also classified into the BP category but associated with the reproductive process.
T316 48872-49238 Sentence denotes The nucleolar remodeling complex-constituting protein BAZ2A and the calcium ion binding protein secretagogin were clustered into the same CC category related to synapse.42,43 The apolipoprotein binding protein VLDLR and the cell cycle control and progression-related protein CDK9 were also divided into the CC category but associated with the macromolecular complex.
T317 49239-49442 Sentence denotes In addition, three proteins, FOSL1, NUP37, and DDX55, were annotated to be associated with structural molecule activity, transporter activity and catalytic activity, respectively, within the MF category.
T318 49443-49738 Sentence denotes For further functional annotation of the DEPs, we took a step further by performing COG function classification, which is a widely used tool for analyzing the function and evolution of proteins at the genome scale.44,45 We discovered that most of the DEPs were assigned new biological functions.
T319 49739-50254 Sentence denotes For example, the immune system process-related proteins ISG15, OAS1, IFIT1, and IFIT3 categorized by GO functional annotation, were assigned to be involved in signal transduction mechanisms within the COG function classification; the proteins DDX55, SMARCA2, and ERCC6L belonging to three different GO categories were categorized into the same COG category—chromatin structure and dynamics; and the proteins NFYB, FOSL1, and CTDP1 belonging to the same GO category were still in the same COG category—transcription.
T320 50255-50416 Sentence denotes The aforementioned findings suggested that there exist slight discrepancies in the classification of some proteins between the GO and COG functional annotations.
T321 50417-50550 Sentence denotes This phenomenon is not unanticipated because the two functional annotation tools are based on different classification criteria.41,44
T322 50551-50874 Sentence denotes Next, we made an effort to identify the potential signaling pathways that might exist among the DEPs using KEGG pathway analysis, an extensively used method for the integration and interpretation of high-throughput proteomic and genomic data.35,46,47 We found that the DEPs were related to multitudinous signaling pathways.
T323 50875-51453 Sentence denotes The top five pathways containing ≥4 DEPs included the viral infectious disease pathway, which is involved in eight proteins AKT2, IFIT1, RSAD2, NFYB, ANAPC7, COL4A1, Mx1, and ISG15; the signal transduction pathway, which is involved in six proteins AKT2, BNIP3, PDK1, WDR24, TMEM55B, and COL4A1; the immune system pathway, which is involved in four proteins ISG15, IFIT1, OAS1 and IFIT3; the digestive system pathway, which is involved in four proteins AKT2, MT-2A, COL4A1, and cystatin C; and the cancer pathway, which is involved in four proteins PDK1, AKT2, COL4A1, and CDK9.
T324 51454-51545 Sentence denotes Once again, we found that the same protein can participate in different signaling pathways.
T325 51546-51750 Sentence denotes For instance, ISG15, a IFN-α-inducible protein that is paramount to the host antiviral innate immunity,48 was simultaneously involved in two signaling pathways—viral infectious diseases and immune system.
T326 51751-52124 Sentence denotes IFIT1 (also named p56/ISG56), an innate nucleic acid immune-sensing receptor that can recognize single-stranded viral RNA lacking 2′-O-methylation at the 5′-terminus and thus confers antiviral defense function by disrupting the machinery of host translation initiation,49,50 was also simultaneously related to viral infectious diseases and immune system signaling pathways.
T327 52125-52351 Sentence denotes By contrast, COL4A1, also known as type IV collagen alpha 1 chain, was simultaneously involved in four of the top five signaling pathways, including viral infectious disease, signal transduction, digestive system, and cancers.
T328 52352-52622 Sentence denotes This protein is an integral component of basement membranes, which can inhibit the migration, proliferation and tube formation by endothelial cells via binding to α-1/β-1 integrin, and thus becomes a potential therapeutic candidate for targeting tumor angiogenesis.51,52
T329 52623-52739 Sentence denotes Other interesting signaling pathways included RIG-I-like receptor, PI3K-AKT, mTOR, and autophagy signaling pathways.
T330 52740-53326 Sentence denotes As an important family of cytosolic pattern recognition receptors, RIG-I is responsible for sensing of the invading viral RNA by recognizing its pathogen-associated molecular patterns to activate downstream signaling cascades, and thereby produce type I IFN.53,54 The generated IFN molecules then bind to IFN receptors and activate numerous ISGs, which exert critical antiviral innate immune functions either directly or indirectly.55 In our study, five upregulated proteins encoded by ISGs, including ISG15, OAS1, Mx1, IFIT1, and IFIT3, were identified in PDCoV-infected IPEC-J2 cells.
T331 53327-53537 Sentence denotes Although these proteins related to type I IFN induction have been reported to participate in diverse viral infections,22,56 most of them were identified for the first time to be associated with PDCoV infection.
T332 53538-53655 Sentence denotes These data suggest that the canonical IFN signaling pathways were activated in IPEC-J2 cells upon infection by PDCoV.
T333 53656-54038 Sentence denotes This was further confirmed by a recent transcriptome-level study which also demonstrated that the RIG-I-like receptor signaling pathway was activated in PDCoV-infected cells, even though a different type of cells, PK-15, was used.17 Nevertheless, there is increasing evidence suggesting that PDCoV has evolved multiple escape strategies to interfere with the host’s innate immunity.
T334 54039-54632 Sentence denotes For example, the nsp15 of PDCoV was found to be able to antagonize IFN-β production in LLC-PK1 cells by disrupting the phosphorylation and nuclear translocation of nuclear factor-κB p65 subunit, which is independent of its endoribonuclease activity.57 The Nsp5 of PDCoV was demonstrated to suppress the production of type I IFNs by cleaving the signal transducer and activator of transcription 2, depending on its protease activity.58 Moreover, the PDCoV accessory protein NS6 was shown to antagonize IFN-β production by disrupting the binding of double-stranded RNA to RIG-I/MDA5 receptors.59
T335 54633-56078 Sentence denotes Except for the RIG-I-like signaling pathway, two multifunctional signaling pathways, PI3K-AKT and mTOR, were also activated in PDCoV-infected IPEC-J2 cells, both of which participate in regulating autophagy.60 The PI3K-AKT signaling pathway could be triggered by numerous factors and regulates a variety of fundamental cellular functions, for instance, proliferation and survival.61 Activated AKT subsequently modulates numerous cellular processes, including cellular autophagy, cell cycle progression and cellular survival.62 The mTOR signaling pathway is involved in regulating diverse basic biological processes, including lipid biogenesis, protein synthesis, regulation of autophagy, cytoskeletal organization and so on,63,64 whose dysfunction has been associated with the pathophysiology of many diseases like diabetes and cancer.65 Although the mTOR and PI3K-AKT signaling pathways are able to negatively and positively regulate autophagy, respectively, in an independent manner,60,66−68 they usually coregulate autophagy via merging into a single PI3K-AKT-mTOR signaling pathway, which serves as one of the classical pathways for negatively regulating autophagy.69,70 From the KEGG analysis, we noticed that the PI3K-AKT and mTOR signaling pathways were respectively upregulated and downregulated in PDCoV-infected IPEC-J2 cells, which are the two important indicators of autophagic activation through the PI3K-AKT-mTOR signaling pathway.
T336 56079-56176 Sentence denotes Accordingly, we speculate that PDCoV infection successfully activated autophagy in IPEC-J2 cells.
T337 56177-56345 Sentence denotes Our speculation was in agreement with a recent research which revealed that PDCoV infection triggered autophagy in LLC-PK1 cells,71 despite using a different cell line.
T338 56346-56584 Sentence denotes Undoubtedly, further studies are definitely needed to confirm the autophagy induced by PDCoV infection, to analyze the impact of autophagy on viral replication and to explore the underlying molecular mechanisms of PDCoV-induced autophagy.
T339 56585-56759 Sentence denotes It should be noted that the PI3K-AKT-mTOR signaling pathway also plays an important role in many physiological and pathological conditions,69 except for regulating autophagy.
T340 56760-56990 Sentence denotes Finally, we sought to uncover the hidden interaction networks among the DEPs using STRING analysis, and discovered three major functional networks consisting of the RIG-I-like receptor, PDK1-AKT2 and cell cycle signaling pathways.
T341 56991-57188 Sentence denotes These findings are in accordance with the results of KEGG pathway analysis, thus further consolidating the credibility of these putative signaling pathways involved in PDCoV-infected IPEC-J2 cells.
T342 57189-57316 Sentence denotes Given the former two signaling pathways have already been discussed earlier, we next focus on the cell cycle signaling pathway.
T343 57317-57504 Sentence denotes As can be seen from the network diagram (Figure 6), three small networks with NUP37, SMARCA2, and CDK9 as the respective hub proteins together constitute the cell cycle signaling pathway.
T344 57505-58859 Sentence denotes NUP37 is an important constituent of the nuclear pore Nup107–160 subcomplex, which controls the bidirectional trafficking of macromolecules that traverse the nuclear envelope.72 SMARCA2 is an important member of the SWI/SNF family with helicase and ATPase activities, and has been shown to regulate numerous biological processes such as cell proliferation and DNA repair.73 CDK9 paired with cyclin T1 forms the positive transcription elongation factor b (p-TEFb) complex and induces transcriptional activation by hyperphosphorylating RNA polymerase II, and thereby regulating numerous vital cellular functions including proliferation, differentiation, DNA repair and apoptosis.74,75 However, growing studies suggest that CDK9 is also related to many pathologic processes, such as cancer, cardiovascular diseases and viral replication.74 Currently, CDK9 has been demonstrated to be involved in the replication of multiple viruses, such as influenza A virus, dengue virus, human adenovirus, and human immunodeficiency virus.75 For example, CDK9 was found to interact with the viral RNA-dependent RNA polymerases of influenza A virus and facilitate its association with cellular RNA polymerase II, thereby promoting viral transcription.76 CDK9 was also shown to be critical for the transcription of viral early genes and the replication of human adenovirus.
T345 58860-59221 Sentence denotes Treatment of host cells with the CDK9 inhibitor, FIT-039, which functions by suppressing mRNA transcription, can efficiently inhibits the replication of human adenovirus.77 In the present study, CDK9 was significantly downregulated in IPEC-J2 cells upon PDCoV infection; however, the biological functions hidden behind this change warrant further investigation.
T346 59222-59507 Sentence denotes Of note, it is of great significance to compare our proteomics data with those of the newly emergent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2),78,79 which caused the Coronavirus Disease 2019 (COVID-19) Pandemic and has posed a serious global public health emergency.
T347 59508-59936 Sentence denotes Recently, Appelberg et al. conducted an integrative proteo-transcriptomics analysis of Huh7 cells responding to SARS-CoV-2 infection, and identified ErbB, HIF-1, mTOR, and TNF signaling pathways that were significantly regulated during SARS-CoV-2 infection in vitro.78 They further demonstrated that the Akt inhibitor MK-2206, targeting the mTOR signaling pathway, was able to significantly reduce the replication of SARS-CoV-2.
T348 59937-60499 Sentence denotes Moreover, another recent study investigated the translatome and proteome of Caco-2 cells in response to SARS-CoV-2 infection in vitro, and discovered that several cellular pathways linked to translation, proteostasis, splicing, carbon metabolism, and nucleotide metabolism were reshaped during viral infection.79 On this basis, the authors tested two translation inhibitors, cycloheximide and emetine, for their ability to suppress SARS-CoV-2 replication, and found that both pharmaceuticals significantly decreased the replication of SARS-CoV-2 in Caco-2 cells.
T349 60500-60874 Sentence denotes Undoubtedly, by comparing the similarities and differences of cellular proteomes between PDCoV- and SARS-CoV-2-infected host cells, it is possible to find some common signaling pathways and key adaptor molecules that function to inhibit viral replication, and thus provide valuable clues for screening of therapeutic drugs for PDCoV and designing novel antiviral strategies.
T350 60876-60890 Sentence denotes 5 Conclusions
T351 60891-61091 Sentence denotes The present study provides the first systematic analysis of the global protein profiles of PDCoV-infected IPEC-J2 cells using a quantitative proteomics approach in which iTRAQ was coupled to LC-MS/MS.
T352 61092-61235 Sentence denotes A total of 78 DEPs, including 23 upregulated proteins and 55 downregulated proteins, were identified in PDCoV-infected IPEC-J2 cells at 24 hpi.
T353 61236-61531 Sentence denotes Bioinformatics analyses further revealed that a majority of the DEPs were involved in various crucial biological processes and signaling pathways, such as digestive system, immune system, signal transduction, and RIG-I-like receptor, mTOR, PI3K-AKT, autophagy, and cell cycle signaling pathways.
T354 61532-61771 Sentence denotes Although further investigations are required to elucidate the functions of the DEPs of interest, our current data provide valuable clues for the in-depth investigation of pathogenic mechanisms of PDCoV and defense mechanisms of host cells.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
50 16-40 Species denotes Porcine deltacoronavirus Tax:1586324
51 177-190 Species denotes Coronaviridae Tax:11118
52 259-263 Species denotes pigs Tax:9823
53 375-379 Species denotes pigs Tax:9823
54 647-651 Species denotes pigs Tax:9823
55 855-860 Species denotes swine Tax:9823
56 353-371 Disease denotes diarrheal diseases MESH:D004403
57 396-411 Disease denotes PDCoV infection MESH:D007239
58 632-646 Disease denotes PDCoV-infected MESH:D007239
59 671-679 Disease denotes diarrhea MESH:D003967
60 687-695 Disease denotes vomiting MESH:D014839
61 697-708 Disease denotes dehydration MESH:D003681
62 714-719 Disease denotes death MESH:D003643
63 758-773 Disease denotes PDCoV infection MESH:D007239
85 928-932 Species denotes pigs Tax:9823
86 960-964 Species denotes pigs Tax:9823
87 1318-1322 Species denotes pigs Tax:9823
88 1834-1851 Species denotes porcine rotavirus Tax:10913
89 1887-1891 Species denotes PEDV Tax:28295
90 1900-1935 Species denotes transmissible gastroenteritis virus Tax:11149
91 1937-1941 Species denotes TGEV Tax:11149
92 1047-1054 Species denotes porcine Tax:28344
93 1510-1517 Species denotes porcine Tax:28344
94 1590-1597 Species denotes porcine Tax:28344
95 1801-1808 Species denotes porcine Tax:28344
96 1855-1862 Species denotes porcine Tax:28344
97 1187-1202 Disease denotes PDCoV infection MESH:D007239
98 1226-1233 Disease denotes atrophy MESH:D001284
99 1265-1273 Disease denotes necrosis MESH:D009336
100 1309-1317 Disease denotes infected MESH:D007239
101 1871-1879 Disease denotes diarrhea MESH:D003967
102 2039-2048 Disease denotes infection MESH:D007239
103 1370-1377 CellLine denotes IPEC-J2 CVCL:2246
104 1657-1664 CellLine denotes IPEC-J2 CVCL:2246
105 1994-2001 CellLine denotes IPEC-J2 CVCL:2246
110 2079-2084 Species denotes swine Tax:9823
111 2102-2113 Species denotes coronavirus Tax:11118
112 2745-2765 Disease denotes PDCoV-infected PK-15 MESH:C564858
113 3050-3064 Disease denotes PDCoV-infected MESH:D007239
125 4126-4130 Species denotes TGEV Tax:11149
126 4134-4138 Species denotes PEDV Tax:28295
127 4142-4170 Species denotes foot-and-mouth disease virus Tax:12110
128 4172-4176 Species denotes FMDV Tax:12110
129 4181-4206 Species denotes porcine circovirus type 2 Tax:85708
130 4208-4212 Species denotes PCV2 Tax:85708
131 4219-4246 Species denotes classical swine fever virus Tax:11096
132 4248-4252 Species denotes CSFV Tax:11096
133 3165-3181 Disease denotes viral infections MESH:D001102
134 4632-4641 Disease denotes infection MESH:D007239
135 4597-4604 CellLine denotes IPEC-J2 CVCL:2246
149 5857-5862 Gene denotes IFIT1 Gene:15957
150 5879-5885 Gene denotes ANAPC7 Gene:56317
151 5953-5964 Species denotes Horseradish Tax:3704
152 5376-5382 Species denotes bovine Tax:9913
153 5822-5827 Species denotes Mouse Tax:10090
154 5846-5851 Species denotes mouse Tax:10090
155 5833-5840 Gene denotes β-actin Gene:728378
156 5648-5651 Chemical denotes CO2 MESH:D002245
157 6072-6087 Chemical denotes Alexa Fluor 488
158 4797-4814 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
159 4930-4938 Disease denotes diarrhea MESH:D003967
160 5427-5437 Disease denotes mL insulin MESH:D007333
161 5113-5120 CellLine denotes IPEC-J2 CVCL:2246
173 6260-6285 Chemical denotes phosphate buffered saline
174 6287-6290 Chemical denotes PBS
175 6512-6515 Chemical denotes PBS
176 6531-6535 Chemical denotes DMEM
177 6536-6546 Chemical denotes F12 medium
178 6323-6331 Disease denotes infected MESH:D007239
179 6335-6343 Disease denotes infected MESH:D007239
180 6349-6366 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
181 6395-6404 Disease denotes infection MESH:D007239
182 6187-6194 CellLine denotes IPEC-J2 CVCL:2246
183 6739-6746 CellLine denotes IPEC-J2 CVCL:2246
188 7286-7290 Chemical denotes DMEM
189 7291-7301 Chemical denotes F12 medium
190 6971-6978 CellLine denotes IPEC-J2 CVCL:2246
191 7145-7152 CellLine denotes IPEC-J2 CVCL:2246
200 7744-7747 Chemical denotes CO2 MESH:D002245
201 7791-7798 Chemical denotes ethanol MESH:D000431
202 7850-7853 Chemical denotes PBS
203 7980-7995 Chemical denotes Alexa Fluor 488
204 8134-8137 Chemical denotes PBS
205 7636-7644 Disease denotes infected MESH:D007239
206 7648-7656 Disease denotes infected MESH:D007239
207 7553-7560 CellLine denotes IPEC-J2 CVCL:2246
215 9117-9120 Gene denotes kit Gene:3815
216 8426-8429 Chemical denotes PBS
217 8692-8709 Chemical denotes RIPA lysis buffer
218 8752-8755 Chemical denotes SDS MESH:D012967
219 8761-8765 Chemical denotes urea MESH:D014508
220 8326-8334 Disease denotes infected MESH:D007239
221 8335-8342 CellLine denotes IPEC-J2 CVCL:2246
233 10391-10394 Gene denotes kit Gene:3815
234 9513-9530 Chemical denotes RIPA lysis buffer
235 9566-9597 Chemical denotes tris (2-carboxyethyl) phosphine MESH:C080938
236 9599-9603 Chemical denotes TCEP MESH:C080938
237 9693-9706 Chemical denotes iodoacetamide MESH:D007460
238 9868-9875 Chemical denotes acetone MESH:D000096
239 10065-10093 Chemical denotes triethylammonium bicarbonate MESH:C041737
240 10095-10099 Chemical denotes TEAB MESH:C041737
241 10315-10319 Chemical denotes TEAB MESH:C041737
242 10525-10533 Disease denotes infected MESH:D007239
243 10658-10672 Disease denotes PDCoV-infected MESH:D007239
249 11547-11555 Chemical denotes peptides MESH:D010455
250 11682-11693 Chemical denotes formic acid MESH:C030544
251 11707-11719 Chemical denotes acetonitrile MESH:C032159
252 11758-11769 Chemical denotes formic acid MESH:C030544
253 11784-11796 Chemical denotes acetonitrile MESH:C032159
262 12776-12786 Species denotes Sus scrofa Tax:9823
263 12920-12930 Species denotes Sus scrofa Tax:9823
264 12932-12935 Species denotes Pig Tax:9823
265 12964-12988 Species denotes porcine deltacoronavirus Tax:1586324
266 13117-13141 Species denotes Porcine deltacoronavirus Tax:1586324
267 13491-13502 Species denotes C); maximum Tax:13423
268 14013-14027 Disease denotes PDCoV-infected MESH:D007239
269 14028-14035 CellLine denotes IPEC-J2 CVCL:2246
272 14293-14307 Disease denotes PDCoV-infected MESH:D007239
273 14308-14315 CellLine denotes IPEC-J2 CVCL:2246
293 15871-15877 Gene denotes ANAPC7 Gene:51434
294 15898-15903 Gene denotes IFIT1 Gene:3434
295 16378-16385 Gene denotes β-actin Gene:728378
296 16502-16508 Gene denotes ANAPC7 Gene:51434
297 16510-16515 Gene denotes IFIT1 Gene:3434
298 16520-16527 Gene denotes β-actin Gene:728378
299 16674-16680 Gene denotes ANAPC7 Gene:51434
300 16757-16762 Gene denotes IFIT1 Gene:3434
301 16849-16856 Gene denotes β-actin Gene:728378
302 17310-17316 Gene denotes ANAPC7 Gene:51434
303 17321-17328 Gene denotes β-actin Gene:728378
304 17353-17358 Gene denotes IFIT1 Gene:3434
305 16194-16197 Gene denotes Kit Gene:396810
306 16326-16329 Gene denotes kit Gene:396810
307 16059-16062 Gene denotes kit Gene:396810
308 17466-17473 Gene denotes β-actin Gene:728378
309 17114-17119 Chemical denotes water MESH:D014867
310 15971-15979 Disease denotes infected MESH:D007239
311 15980-15987 CellLine denotes IPEC-J2 CVCL:2246
326 17599-17605 Gene denotes ANAPC7 Gene:51434
327 17610-17615 Gene denotes IFIT1 Gene:3434
328 17648-17655 Gene denotes β-actin Gene:728378
329 18007-18010 Gene denotes Rad Gene:6236
330 18140-18146 Gene denotes ANAPC7 Gene:51434
331 18162-18167 Gene denotes IFIT1 Gene:3434
332 18491-18494 Gene denotes kit Gene:3815
333 18186-18193 Gene denotes β-actin Gene:728378
334 17840-17843 Chemical denotes SDS MESH:D012967
335 17883-17908 Chemical denotes poly(vinylidene fluoride) MESH:C024865
336 17910-17914 Chemical denotes PVDF MESH:C024865
337 17748-17762 Disease denotes PDCoV-infected MESH:D007239
338 18080-18088 Disease denotes dry milk MESH:D016269
339 17763-17770 CellLine denotes IPEC-J2 CVCL:2246
342 19811-19832 Disease denotes synchronous infection MESH:D009378
343 19581-19588 CellLine denotes IPEC-J2 CVCL:2246
345 20386-20395 Disease denotes Infection MESH:D007239
358 21377-21382 Species denotes swine Tax:9823
359 20484-20493 Disease denotes infection MESH:D007239
360 20782-20790 Disease denotes infected MESH:D007239
361 20924-20933 Disease denotes infection MESH:D007239
362 21362-21376 Disease denotes PDCoV-infected MESH:D007239
363 21711-21719 Disease denotes infected MESH:D007239
364 22238-22252 Disease denotes PDCoV-infected MESH:D007239
365 20495-20502 CellLine denotes IPEC-J2 CVCL:2246
366 20750-20757 CellLine denotes IPEC-J2 CVCL:2246
367 20815-20822 CellLine denotes IPEC-J2 CVCL:2246
368 21560-21567 CellLine denotes IPEC-J2 CVCL:2246
369 22253-22260 CellLine denotes IPEC-J2 CVCL:2246
382 22638-22641 Chemical denotes α-N
383 22650-22665 Chemical denotes Alexa Fluor 488
384 22795-22799 Chemical denotes DAPI MESH:C007293
385 22362-22370 Disease denotes infected MESH:D007239
386 22380-22397 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
387 22444-22452 Disease denotes infected MESH:D007239
388 22703-22711 Disease denotes infected MESH:D007239
389 22918-22933 Disease denotes viral infection MESH:D001102
390 22304-22311 CellLine denotes IPEC-J2 CVCL:2246
391 22348-22355 CellLine denotes IPEC-J2 CVCL:2246
392 22557-22564 CellLine denotes IPEC-J2 CVCL:2246
393 22865-22872 CellLine denotes IPEC-J2 CVCL:2246
396 23126-23135 Disease denotes Infection MESH:D007239
397 23091-23098 CellLine denotes IPEC-J2 CVCL:2246
415 23890-23894 Gene denotes Nsp5 Gene:92521
416 23923-23926 Gene denotes NS7 Gene:673
417 23915-23918 Gene denotes NS6 Gene:4893
418 24030-24054 Species denotes porcine deltacoronavirus Tax:1586324
419 24527-24531 Species denotes pigs Tax:9823
420 24579-24584 Species denotes human Tax:9606
421 23167-23182 Disease denotes viral infection MESH:D001102
422 23243-23251 Disease denotes infected MESH:D007239
423 23429-23437 Disease denotes infected MESH:D007239
424 23688-23702 Disease denotes PDCoV-infected MESH:D007239
425 23745-23753 Disease denotes infected MESH:D007239
426 23976-23990 Disease denotes PDCoV-infected MESH:D007239
427 24186-24194 Disease denotes infected MESH:D007239
428 23252-23259 CellLine denotes IPEC-J2 CVCL:2246
429 23438-23445 CellLine denotes IPEC-J2 CVCL:2246
430 23703-23710 CellLine denotes IPEC-J2 CVCL:2246
431 23991-23998 CellLine denotes IPEC-J2 CVCL:2246
512 25054-25059 Gene denotes ISG15 Gene:9636
513 25122-25127 Gene denotes RIG-1 Gene:5920
514 25128-25132 Gene denotes MDA5 Gene:64135
515 25155-25169 Gene denotes IFN-alpha/beta Gene:3440
516 25366-25423 Gene denotes Radical S-adenosyl methionine domain-containing protein 2 Gene:91543
517 25488-25547 Gene denotes Interferon induced protein with tetratricopeptide repeats 1 Gene:3434
518 25549-25554 Gene denotes IFIT1 Gene:3434
519 25812-25815 Gene denotes Mx1 Gene:4599
520 25919-25924 Gene denotes NUP37 Gene:79023
521 26029-26033 Gene denotes NFYB Gene:4801
522 26159-26165 Gene denotes ERCC6L Gene:54821
523 26223-26247 Gene denotes Collagen type IV alpha 1 Gene:1282
524 26405-26411 Gene denotes MRPL32 Gene:64983
525 26456-26466 Gene denotes Phostensin Gene:170954
526 26518-26539 Gene denotes Bridging integrator 1 Gene:274
527 26698-26710 Gene denotes Secretagogin Gene:10590
528 26712-26716 Gene denotes SCGN Gene:10590
529 26765-26804 Gene denotes Interleukin 13 receptor subunit alpha 2 Gene:3598
530 26916-26921 Gene denotes FOSL1 Gene:8061
531 26996-27005 Gene denotes Prolactin Gene:5617
532 27091-27133 Gene denotes CDK-activating kinase assembly factor MAT1 Gene:4331
533 27135-27140 Gene denotes MNAT1 Gene:4331
534 27325-27362 Gene denotes Very low density lipoprotein receptor Gene:7436
535 27364-27369 Gene denotes VLDLR Gene:7436
536 27555-27589 Gene denotes Helicase-like transcription factor Gene:6596
537 27591-27595 Gene denotes HLTF Gene:6596
538 27762-27793 Gene denotes Nucleoside diphosphate kinase 7 Gene:29922
539 27795-27799 Gene denotes NME7 Gene:29922
540 27918-27923 Gene denotes BAZ2A Gene:11176
541 28095-28100 Gene denotes DDX55 Gene:57696
542 28153-28160 Gene denotes TMEM55B Gene:90809
543 28212-28249 Gene denotes Chromatin assembly factor 1 subunit A Gene:10036
544 28251-28257 Gene denotes CHAF1A Gene:10036
545 28320-28377 Gene denotes RNA polymerase II subunit A C-terminal domain phosphatase Gene:9150
546 28379-28384 Gene denotes CTDP1 Gene:9150
547 28634-28660 Gene denotes Myocyte enhancer factor 2D Gene:4209
548 28944-28980 Gene denotes Anaphase promoting complex subunit 7 Gene:51434
549 28982-28988 Gene denotes ANAPC7 Gene:51434
550 29243-29273 Gene denotes Ubiquitin associated protein 2 Gene:55833
551 29275-29280 Gene denotes UBAP2 Gene:55833
552 29705-29709 Gene denotes CDK9 Gene:1025
553 30245-30250 Gene denotes WDR24 Gene:84219
554 30331-30334 Gene denotes TOR Gene:6097
555 30345-30350 Gene denotes CD109 Gene:135228
556 30495-30499 Gene denotes AKT2 Gene:208
557 30555-30597 Gene denotes DNA polymerase delta interacting protein 3 Gene:84271
558 30599-30606 Gene denotes POLDIP3 Gene:84271
559 30652-30688 Gene denotes Exostosin-like glycosyltransferase 2 Gene:2135
560 30874-30902 Gene denotes Integrator complex subunit 4 Gene:92105
561 30904-30909 Gene denotes INTS4 Gene:92105
562 31347-31357 Gene denotes Cadherin 6 Gene:1004
563 31530-31538 Gene denotes C16orf42 Gene:115939
564 31550-31557 Gene denotes SMARCA2 Gene:6595
565 31631-31637 Gene denotes zyg-11 Gene:440590
566 31763-31767 Gene denotes BCL2 Gene:596
567 31856-31886 Gene denotes Alpha-(1,6)-fucosyltransferase Gene:2530
568 31888-31892 Gene denotes FUT8 Gene:2530
569 31926-31956 Gene denotes Alpha-(1→6)-fucosyltransferase Gene:2530
570 31966-31998 Gene denotes Signal peptide peptidase-like 2B Gene:56928
571 32065-32070 Gene denotes INTS3 Gene:65123
572 32101-32106 Gene denotes INTS4 Gene:92105
573 32460-32478 Gene denotes Metallothionein-2A Gene:4502
574 29801-29811 Gene denotes Cystatin C Gene:1471
575 28662-28667 Gene denotes MEF2D Gene:4209
576 28085-28093 Gene denotes helicase Gene:164045
577 28911-28917 Chemical denotes serine MESH:D012694
578 29531-29537 Chemical denotes serine MESH:D012694
579 29768-29774 Chemical denotes serine MESH:D012694
580 30022-30028 Chemical denotes serine MESH:D012694
581 30086-30092 Chemical denotes serine MESH:D012694
582 30462-30468 Chemical denotes serine MESH:D012694
583 32212-32218 Chemical denotes Serine MESH:D012694
584 32251-32258 Chemical denotes glucose MESH:D005947
585 24936-24945 Disease denotes infection MESH:D007239
586 25033-25047 Disease denotes PDCoV-infected MESH:D007239
587 27304-27318 Disease denotes PDCoV-infected MESH:D007239
588 27484-27500 Disease denotes Myeloid leukemia MESH:D007951
589 29124-29130 Disease denotes cancer MESH:D009369
590 30859-30873 Disease denotes proteotoxicity
591 29711-29717 CellLine denotes C9E1C9 CVCL:F711
594 24876-24885 Disease denotes Infection MESH:D007239
595 24841-24848 CellLine denotes IPEC-J2 CVCL:2246
618 32916-32922 Gene denotes ANAPC7 Gene:51434
619 32943-32948 Gene denotes IFIT1 Gene:3434
620 33176-33182 Gene denotes ANAPC7 Gene:51434
621 33187-33192 Gene denotes IFIT1 Gene:3434
622 33519-33525 Gene denotes ANAPC7 Gene:100155743
623 33530-33535 Gene denotes IFIT1 Gene:100153038
624 33891-33897 Gene denotes ANAPC7 Gene:51434
625 33932-33939 Gene denotes β-actin Gene:728378
626 33980-33985 Gene denotes IFIT1 Gene:3434
627 34020-34027 Gene denotes β-actin Gene:728378
628 34141-34145 Chemical denotes PVDF MESH:C024865
629 32987-32995 Disease denotes infected MESH:D007239
630 32999-33007 Disease denotes infected MESH:D007239
631 33253-33267 Disease denotes PDCoV-infected MESH:D007239
632 33313-33321 Disease denotes infected MESH:D007239
633 33574-33582 Disease denotes infected MESH:D007239
634 33695-33710 Disease denotes PDCoV infection MESH:D007239
635 33819-33827 Disease denotes infected MESH:D007239
636 34090-34105 Disease denotes PDCoV infection MESH:D007239
637 32963-32970 CellLine denotes IPEC-J2 CVCL:2246
638 33548-33561 CellLine denotes IPEC-J2 cells CVCL:2246
639 33828-33835 CellLine denotes IPEC-J2 CVCL:2246
667 34577-34583 Gene denotes ANAPC7 Gene:100155743
668 34588-34593 Gene denotes IFIT1 Gene:100153038
669 34931-34938 Gene denotes β-actin Gene:728378
670 35094-35100 Gene denotes ANAPC7 Gene:51434
671 35105-35110 Gene denotes IFIT1 Gene:3434
672 35131-35138 Gene denotes β-actin Gene:728378
673 35364-35370 Gene denotes ANAPC7 Gene:100155743
674 35375-35380 Gene denotes IFIT1 Gene:100153038
675 35622-35628 Gene denotes ANAPC7 Gene:56317
676 35641-35646 Gene denotes IFIT1 Gene:15957
677 35705-35712 Gene denotes β-Actin Gene:728378
678 36003-36010 Gene denotes β-actin Gene:728378
679 35630-35635 Species denotes mouse Tax:10090
680 34622-34631 Disease denotes infection MESH:D007239
681 34657-34665 Disease denotes infected MESH:D007239
682 34669-34677 Disease denotes infected MESH:D007239
683 34687-34704 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
684 35163-35171 Disease denotes infected MESH:D007239
685 35418-35427 Disease denotes infection MESH:D007239
686 35453-35461 Disease denotes infected MESH:D007239
687 35465-35473 Disease denotes infected MESH:D007239
688 35483-35500 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
689 35894-35913 Disease denotes PDCoV-infected band MESH:D058745
690 34597-34604 CellLine denotes IPEC-J2 CVCL:2246
691 34633-34640 CellLine denotes IPEC-J2 CVCL:2246
692 35393-35400 CellLine denotes IPEC-J2 CVCL:2246
693 35429-35436 CellLine denotes IPEC-J2 CVCL:2246
696 37538-37547 Disease denotes infection MESH:D007239
697 37513-37520 CellLine denotes IPEC-J2 CVCL:2246
700 39186-39198 Chemical denotes carbohydrate MESH:D002241
701 39349-39354 Chemical denotes lipid MESH:D008055
704 39896-39905 Disease denotes infection MESH:D007239
705 39871-39878 CellLine denotes IPEC-J2 CVCL:2246
727 40949-40952 Gene denotes AKT Gene:207
728 41174-41178 Gene denotes mTOR Gene:2475
729 41261-41273 Gene denotes Secretagogin Gene:10590
730 41306-41310 Gene denotes AKT2 Gene:208
731 41598-41603 Gene denotes HIF-1 Gene:3091
732 41673-41676 Gene denotes AGE Gene:5973
733 40607-40612 Species denotes human Tax:9606
734 42087-42092 Species denotes human Tax:9606
735 41764-41773 Species denotes influenza Tax:11320
736 41347-41354 Chemical denotes gamma R
737 41735-41741 Chemical denotes carbon MESH:D002244
738 41844-41861 Chemical denotes glycosaminoglycan MESH:D006025
739 41876-41888 Chemical denotes progesterone MESH:D011374
740 40405-40424 Disease denotes infectious diseases MESH:D003141
741 40483-40490 Disease denotes cancers MESH:D009369
742 40997-41003 Disease denotes cancer MESH:D009369
743 41623-41639 Disease denotes HTLV-I infection MESH:D015490
744 41647-41671 Disease denotes papillomavirus infection MESH:D030361
745 41703-41725 Disease denotes diabetic complications MESH:D048909
746 41756-41762 Disease denotes cancer MESH:D009369
747 41820-41842 Disease denotes small cell lung cancer MESH:D055752
752 42520-42525 Species denotes human Tax:9606
753 42266-42275 Disease denotes infection MESH:D007239
754 42536-42538 Disease denotes HD MESH:D006816
755 42241-42248 CellLine denotes IPEC-J2 CVCL:2246
794 43692-43697 Gene denotes NUP37 Gene:79023
795 43855-43859 Gene denotes SCGN Gene:10590
796 43860-43865 Gene denotes ISG15 Gene:9636
797 43866-43870 Gene denotes OAS1 Gene:4938
798 43871-43876 Gene denotes IFIT1 Gene:3434
799 43877-43882 Gene denotes IFIT3 Gene:3437
800 43883-43889 Gene denotes ANAPC7 Gene:51434
801 43890-43894 Gene denotes NME7 Gene:29922
802 43943-43950 Gene denotes POLDIP3 Gene:84271
803 43951-43956 Gene denotes NUP37 Gene:79023
804 43957-43963 Gene denotes ERCC6L Gene:54821
805 43964-43969 Gene denotes DDX55 Gene:57696
806 43970-43977 Gene denotes SMARCA2 Gene:6595
807 43983-43988 Gene denotes BAZ2A Gene:11176
808 43989-43993 Gene denotes HLTF Gene:6596
809 43994-44000 Gene denotes CHAF1A Gene:10036
810 44001-44005 Gene denotes CDK9 Gene:1025
811 44006-44011 Gene denotes MNAT1 Gene:4331
812 44012-44017 Gene denotes CTDP1 Gene:9150
813 44018-44023 Gene denotes INTS4 Gene:92105
814 44190-44195 Gene denotes IFIT1 Gene:3434
815 44197-44202 Gene denotes IFIT3 Gene:3437
816 44204-44209 Gene denotes NUP37 Gene:79023
817 44211-44218 Gene denotes SMARCA2 Gene:6595
818 44224-44228 Gene denotes CDK9 Gene:1025
819 44245-44250 Gene denotes MNAT1 Gene:4331
820 44274-44279 Gene denotes CTDP1 Gene:9150
821 44284-44288 Gene denotes CDK9 Gene:1025
822 44294-44299 Gene denotes INTS4 Gene:92105
823 44327-44331 Gene denotes CDK9 Gene:1025
824 44458-44463 Gene denotes MEF2D Gene:4209
825 44465-44470 Gene denotes VLDLR Gene:7436
826 44483-44487 Gene denotes PDK1 Gene:5163
827 44493-44497 Gene denotes AKT2 Gene:208
828 44437-44446 Disease denotes infection MESH:D007239
829 44525-44530 Disease denotes death MESH:D003643
830 44725-44740 Disease denotes PDCoV infection MESH:D007239
831 44744-44751 CellLine denotes IPEC-J2 CVCL:2246
834 44975-44984 Disease denotes infection MESH:D007239
835 44950-44957 CellLine denotes IPEC-J2 CVCL:2246
852 46918-46921 Gene denotes NS6 Gene:4893
853 46923-46926 Gene denotes NS7 Gene:673
854 46932-46936 Gene denotes Nsp5 Gene:92521
855 46588-46592 Species denotes pigs Tax:9823
856 46357-46364 Species denotes porcine Tax:28344
857 45602-45617 Disease denotes viral infection MESH:D001102
858 45868-45884 Disease denotes viral infections MESH:D001102
859 46075-46084 Disease denotes infection MESH:D007239
860 46172-46186 Disease denotes PDCoV-infected MESH:D007239
861 46326-46335 Disease denotes infection MESH:D007239
862 46405-46420 Disease denotes PDCoV infection MESH:D007239
863 46615-46630 Disease denotes PDCoV infection MESH:D007239
864 46690-46704 Disease denotes PDCoV-infected MESH:D007239
865 46187-46194 CellLine denotes IPEC-J2 CVCL:2246
866 46449-46456 CellLine denotes IPEC-J2 CVCL:2246
867 46705-46712 CellLine denotes IPEC-J2 CVCL:2246
880 47088-47094 Gene denotes ANAPC7 Gene:51434
881 47099-47104 Gene denotes IFIT1 Gene:3434
882 47182-47188 Gene denotes ANAPC7 Gene:51434
883 47487-47493 Gene denotes ANAPC7 Gene:100155743
884 47567-47572 Gene denotes IFIT1 Gene:3434
885 47771-47776 Gene denotes IFIT1 Gene:3434
886 47677-47692 Chemical denotes 5′-triphosphate
887 47511-47522 Disease denotes dysfunction MESH:D009461
888 47550-47565 Disease denotes PDCoV infection MESH:D007239
889 47832-47846 Disease denotes PDCoV-infected MESH:D007239
890 47526-47533 CellLine denotes IPEC-J2 CVCL:2246
891 47847-47854 CellLine denotes IPEC-J2 CVCL:2246
920 48586-48591 Gene denotes ISG15 Gene:9636
921 48593-48597 Gene denotes OAS1 Gene:4938
922 48599-48602 Gene denotes Mx1 Gene:4599
923 48604-48609 Gene denotes IFIT1 Gene:3434
924 48615-48620 Gene denotes IFIT3 Gene:3437
925 48746-48752 Gene denotes ERCC6L Gene:54821
926 48754-48758 Gene denotes NME7 Gene:29922
927 48760-48764 Gene denotes NFYB Gene:4801
928 48766-48771 Gene denotes FOSL1 Gene:8061
929 48777-48782 Gene denotes CTDP1 Gene:9150
930 48926-48931 Gene denotes BAZ2A Gene:11176
931 48968-48980 Gene denotes secretagogin Gene:10590
932 49082-49087 Gene denotes VLDLR Gene:7436
933 49147-49151 Gene denotes CDK9 Gene:1025
934 49268-49273 Gene denotes FOSL1 Gene:8061
935 49275-49280 Gene denotes NUP37 Gene:79023
936 49286-49291 Gene denotes DDX55 Gene:57696
937 49795-49800 Gene denotes ISG15 Gene:9636
938 49802-49806 Gene denotes OAS1 Gene:4938
939 49808-49813 Gene denotes IFIT1 Gene:3434
940 49819-49824 Gene denotes IFIT3 Gene:3437
941 49982-49987 Gene denotes DDX55 Gene:57696
942 49989-49996 Gene denotes SMARCA2 Gene:6595
943 50002-50008 Gene denotes ERCC6L Gene:54821
944 50147-50151 Gene denotes NFYB Gene:4801
945 50153-50158 Gene denotes FOSL1 Gene:8061
946 50164-50169 Gene denotes CTDP1 Gene:9150
947 48940-48947 Chemical denotes calcium MESH:D002118
989 50999-51003 Gene denotes AKT2 Gene:208
990 51005-51010 Gene denotes IFIT1 Gene:3434
991 51012-51017 Gene denotes RSAD2 Gene:91543
992 51019-51023 Gene denotes NFYB Gene:4801
993 51025-51031 Gene denotes ANAPC7 Gene:51434
994 51033-51039 Gene denotes COL4A1 Gene:1282
995 51041-51044 Gene denotes Mx1 Gene:4599
996 51050-51055 Gene denotes ISG15 Gene:9636
997 51124-51128 Gene denotes AKT2 Gene:208
998 51130-51135 Gene denotes BNIP3 Gene:664
999 51137-51141 Gene denotes PDK1 Gene:5163
1000 51143-51148 Gene denotes WDR24 Gene:84219
1001 51150-51157 Gene denotes TMEM55B Gene:90809
1002 51163-51169 Gene denotes COL4A1 Gene:1282
1003 51233-51238 Gene denotes ISG15 Gene:9636
1004 51240-51245 Gene denotes IFIT1 Gene:3434
1005 51247-51251 Gene denotes OAS1 Gene:4938
1006 51256-51261 Gene denotes IFIT3 Gene:3437
1007 51328-51332 Gene denotes AKT2 Gene:208
1008 51334-51339 Gene denotes MT-2A Gene:4502
1009 51341-51347 Gene denotes COL4A1 Gene:1282
1010 51353-51363 Gene denotes cystatin C Gene:1471
1011 51424-51428 Gene denotes PDK1 Gene:5163
1012 51430-51434 Gene denotes AKT2 Gene:208
1013 51436-51442 Gene denotes COL4A1 Gene:1282
1014 51448-51452 Gene denotes CDK9 Gene:1025
1015 51560-51565 Gene denotes ISG15 Gene:9636
1016 51569-51574 Gene denotes IFN-α Gene:3439
1017 51751-51756 Gene denotes IFIT1 Gene:3434
1018 51769-51772 Gene denotes p56 Gene:3434
1019 51773-51778 Gene denotes ISG56 Gene:3434
1020 52138-52144 Gene denotes COL4A1 Gene:1282
1021 52515-52519 Gene denotes α-1/ Gene:597
1022 52519-52531 Gene denotes β-1 integrin Gene:3688
1023 50929-50953 Disease denotes viral infectious disease MESH:D001102
1024 51373-51379 Disease denotes cancer MESH:D009369
1025 51712-51731 Disease denotes infectious diseases MESH:D003141
1026 52067-52086 Disease denotes infectious diseases MESH:D003141
1027 52280-52298 Disease denotes infectious disease MESH:D003141
1028 52343-52350 Disease denotes cancers MESH:D009369
1029 52598-52603 Disease denotes tumor MESH:D009369
1052 52695-52698 Gene denotes AKT Gene:207
1053 52700-52704 Gene denotes mTOR Gene:2475
1054 52807-52812 Gene denotes RIG-I Gene:23586
1055 53242-53247 Gene denotes ISG15 Gene:9636
1056 53249-53253 Gene denotes OAS1 Gene:4938
1057 53255-53258 Gene denotes Mx1 Gene:4599
1058 53260-53265 Gene denotes IFIT1 Gene:3434
1059 53271-53276 Gene denotes IFIT3 Gene:3437
1060 54106-54111 Gene denotes IFN-β Gene:3439
1061 54295-54299 Gene denotes Nsp5 Gene:92521
1062 54384-54434 Gene denotes signal transducer and activator of transcription 2 Gene:6773
1063 54512-54515 Gene denotes NS6 Gene:4893
1064 54540-54545 Gene denotes IFN-β Gene:3439
1065 54609-54614 Gene denotes RIG-I Gene:23586
1066 54615-54619 Gene denotes MDA5 Gene:64135
1067 53297-53311 Disease denotes PDCoV-infected MESH:D007239
1068 53428-53444 Disease denotes viral infections MESH:D001102
1069 53521-53536 Disease denotes PDCoV infection MESH:D007239
1070 53636-53645 Disease denotes infection MESH:D007239
1071 53809-53823 Disease denotes PDCoV-infected MESH:D007239
1072 53312-53319 CellLine denotes IPEC-J2 CVCL:2246
1073 53617-53624 CellLine denotes IPEC-J2 CVCL:2246
1103 54648-54653 Gene denotes RIG-I Gene:23586
1104 54723-54726 Gene denotes AKT Gene:207
1105 54731-54735 Gene denotes mTOR Gene:2475
1106 54852-54855 Gene denotes AKT Gene:100126861
1107 55026-55029 Gene denotes AKT Gene:100126861
1108 55164-55168 Gene denotes mTOR Gene:100127359
1109 55484-55488 Gene denotes mTOR Gene:2475
1110 55498-55501 Gene denotes AKT Gene:207
1111 55692-55695 Gene denotes AKT Gene:207
1112 55696-55700 Gene denotes mTOR Gene:2475
1113 55857-55860 Gene denotes AKT Gene:207
1114 55865-55869 Gene denotes mTOR Gene:2475
1115 56051-56054 Gene denotes AKT Gene:100126861
1116 56055-56059 Gene denotes mTOR Gene:100127359
1117 56618-56621 Gene denotes AKT Gene:207
1118 56622-56626 Gene denotes mTOR Gene:2475
1119 55747-55756 Species denotes classical Tax:11096
1120 55259-55264 Chemical denotes lipid MESH:D008055
1121 54760-54774 Disease denotes PDCoV-infected MESH:D007239
1122 55369-55380 Disease denotes dysfunction MESH:D009461
1123 55448-55456 Disease denotes diabetes MESH:D003920
1124 55461-55467 Disease denotes cancer MESH:D009369
1125 55940-55954 Disease denotes PDCoV-infected MESH:D007239
1126 56116-56125 Disease denotes infection MESH:D007239
1127 56259-56268 Disease denotes infection MESH:D007239
1128 56439-56448 Disease denotes infection MESH:D007239
1129 54775-54782 CellLine denotes IPEC-J2 CVCL:2246
1130 55955-55962 CellLine denotes IPEC-J2 CVCL:2246
1131 56162-56169 CellLine denotes IPEC-J2 CVCL:2246
1163 56946-56950 Gene denotes PDK1 Gene:5163
1164 56951-56955 Gene denotes AKT2 Gene:208
1165 57395-57400 Gene denotes NUP37 Gene:79023
1166 57402-57409 Gene denotes SMARCA2 Gene:6595
1167 57415-57419 Gene denotes CDK9 Gene:100307051
1168 57505-57510 Gene denotes NUP37 Gene:79023
1169 57559-57565 Gene denotes Nup107 Gene:57122
1170 57683-57690 Gene denotes SMARCA2 Gene:6595
1171 57879-57883 Gene denotes CDK9 Gene:100307051
1172 57896-57905 Gene denotes cyclin T1 Gene:904
1173 58226-58230 Gene denotes CDK9 Gene:100307051
1174 58353-58357 Gene denotes CDK9 Gene:1025
1175 58543-58547 Gene denotes CDK9 Gene:1025
1176 58741-58745 Gene denotes CDK9 Gene:1025
1177 58893-58897 Gene denotes CDK9 Gene:1025
1178 59055-59059 Gene denotes CDK9 Gene:100307051
1179 57741-57749 Gene denotes helicase Gene:164045
1180 58443-58460 Species denotes influenza A virus Tax:11320
1181 58462-58474 Species denotes dengue virus Tax:12637
1182 58476-58492 Species denotes human adenovirus Tax:1907210
1183 58498-58526 Species denotes human immunodeficiency virus Tax:12721
1184 58618-58635 Species denotes influenza A virus Tax:11320
1185 58842-58858 Species denotes human adenovirus Tax:1907210
1186 59013-59029 Species denotes human adenovirus Tax:1907210
1187 58909-58916 Chemical denotes FIT-039 MESH:C000595272
1188 57159-57173 Disease denotes PDCoV-infected MESH:D007239
1189 58285-58291 Disease denotes cancer MESH:D009369
1190 58293-58316 Disease denotes cardiovascular diseases MESH:D002318
1191 59120-59129 Disease denotes infection MESH:D007239
1192 57174-57181 CellLine denotes IPEC-J2 CVCL:2246
1193 59095-59102 CellLine denotes IPEC-J2 CVCL:2246
1219 59657-59661 Gene denotes ErbB Gene:1956
1220 59663-59668 Gene denotes HIF-1 Gene:3091
1221 59670-59674 Gene denotes mTOR Gene:2475
1222 59680-59683 Gene denotes TNF Gene:7124
1223 59812-59815 Gene denotes Akt Gene:207
1224 59849-59853 Gene denotes mTOR Gene:2475
1225 59323-59370 Species denotes severe acute respiratory syndrome coronavirus-2 Tax:2697049
1226 59372-59382 Species denotes SARS-CoV-2 Tax:2697049
1227 59925-59935 Species denotes SARS-CoV-2 Tax:2697049
1228 60369-60379 Species denotes SARS-CoV-2 Tax:2697049
1229 60472-60482 Species denotes SARS-CoV-2 Tax:2697049
1230 59826-59833 Chemical denotes MK-2206 MESH:C548887
1231 60165-60171 Chemical denotes carbon MESH:D002244
1232 60312-60325 Chemical denotes cycloheximide MESH:D003513
1233 60330-60337 Chemical denotes emetine MESH:D004640
1234 59407-59431 Disease denotes Coronavirus Disease 2019 MESH:C000657245
1235 59433-59441 Disease denotes COVID-19 MESH:C000657245
1236 59620-59640 Disease denotes SARS-CoV-2 infection MESH:C000657245
1237 59744-59764 Disease denotes SARS-CoV-2 infection MESH:C000657245
1238 60041-60061 Disease denotes SARS-CoV-2 infection MESH:C000657245
1239 60231-60246 Disease denotes viral infection MESH:D001102
1240 60600-60619 Disease denotes SARS-CoV-2-infected MESH:C000657245
1241 59595-59599 CellLine denotes Huh7 CVCL:0336
1242 60013-60019 CellLine denotes Caco-2 CVCL:0025
1243 60486-60492 CellLine denotes Caco-2 CVCL:0025
1250 61470-61474 Gene denotes mTOR Gene:2475
1251 61481-61484 Gene denotes AKT Gene:207
1252 60982-60996 Disease denotes PDCoV-infected MESH:D007239
1253 61196-61210 Disease denotes PDCoV-infected MESH:D007239
1254 60997-61004 CellLine denotes IPEC-J2 CVCL:2246
1255 61211-61218 CellLine denotes IPEC-J2 CVCL:2246