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PMC:7640975 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T47 5632-5640 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T1 43-53 Body_part denotes Intestinal http://purl.org/sig/ont/fma/fma7199
T2 54-70 Body_part denotes Epithelial Cells http://purl.org/sig/ont/fma/fma66768
T3 65-70 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T4 266-282 Body_part denotes small intestinal http://purl.org/sig/ont/fma/fma7200
T5 283-299 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T6 294-299 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T7 330-335 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T8 572-580 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T9 614-619 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T10 687-695 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T11 979-986 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T12 1359-1372 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T13 1374-1390 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T14 1465-1469 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T15 1568-1573 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T16 1764-1767 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T17 1768-1774 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T18 2601-2616 Body_part denotes small intestine http://purl.org/sig/ont/fma/fma7200
T19 2644-2651 Body_part denotes jejunum http://purl.org/sig/ont/fma/fma7207
T20 2656-2661 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T21 2715-2731 Body_part denotes small intestinal http://purl.org/sig/ont/fma/fma7200
T22 2732-2748 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T23 2743-2748 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T24 2879-2885 Body_part denotes villus http://purl.org/sig/ont/fma/fma82505
T25 2937-2953 Body_part denotes small intestinal http://purl.org/sig/ont/fma/fma7200
T26 2954-2965 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T27 3038-3042 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T28 3082-3089 Body_part denotes jejunum http://purl.org/sig/ont/fma/fma7207
T29 3178-3188 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T30 3197-3213 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T31 3208-3213 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 3293-3297 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T33 3325-3330 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T34 3440-3456 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T35 3451-3456 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T36 3662-3667 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T37 3922-3926 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T38 3966-3970 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T39 4008-4012 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T40 4151-4156 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T41 4256-4260 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T42 4426-4431 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 4468-4471 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T44 4725-4730 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T45 5091-5102 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T46 5106-5110 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T48 5802-5806 Body_part denotes foot http://purl.org/sig/ont/fma/fma9664
T49 5811-5816 Body_part denotes mouth http://purl.org/sig/ont/fma/fma49184
T50 6265-6270 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 6431-6436 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T52 6442-6452 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T53 6553-6563 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T54 6613-6619 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T55 6628-6633 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 6698-6704 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T57 6781-6786 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T58 6908-6913 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T59 7043-7048 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T60 7090-7097 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365
T61 7263-7268 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T62 7383-7391 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T63 7442-7449 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T64 7495-7500 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T65 7675-7691 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T66 7693-7696 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T67 7774-7777 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T68 7855-7860 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T69 8089-8093 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T70 8136-8141 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 8180-8185 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T72 8268-8273 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T73 8407-8412 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T74 8639-8644 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T75 8813-8818 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T76 8935-8940 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T77 9221-9226 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T78 9356-9360 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T79 9413-9418 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T80 9519-9524 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T81 9682-9685 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T82 9730-9735 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T83 9799-9804 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T84 9886-9893 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T85 10003-10008 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T86 10039-10044 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T87 10126-10130 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T88 10297-10301 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T89 10466-10470 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T90 10682-10690 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T91 10713-10720 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T92 10763-10770 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T93 10840-10848 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T94 11064-11071 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T95 11116-11124 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T96 11283-11290 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T97 11420-11427 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T98 11553-11560 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T99 11776-11783 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T100 13528-13537 Body_part denotes capillary http://purl.org/sig/ont/fma/fma63194
T101 14921-14929 Body_part denotes cysteine http://purl.org/sig/ont/fma/fma82751
T102 15027-15034 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T103 15370-15377 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T104 15496-15503 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T105 15646-15654 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T106 15696-15701 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T107 15712-15720 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T108 15976-15981 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 16000-16004 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T110 16431-16438 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T111 16625-16632 Body_part denotes Genomes http://purl.org/sig/ont/fma/fma84116
T112 17136-17143 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T113 17144-17151 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T114 17480-17484 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T115 17603-17606 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T116 17648-17653 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 17704-17707 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T118 17801-17804 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T119 18040-18045 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T120 18064-18068 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T121 18182-18187 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T122 18511-18516 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T123 18983-18988 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T124 19128-19133 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T125 19144-19148 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T126 19276-19283 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T127 19310-19315 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T128 19364-19372 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T129 19431-19436 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T130 19462-19469 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T131 19657-19661 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T132 19744-19748 Body_part denotes milk http://purl.org/sig/ont/fma/fma62100
T133 19848-19853 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T134 20060-20067 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T135 21249-21254 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T136 21343-21347 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T137 21504-21509 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T138 21535-21540 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T139 21650-21655 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T140 21674-21679 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T141 21832-21840 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T142 22163-22168 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T143 22294-22298 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T144 22418-22423 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T145 22451-22456 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T146 22483-22488 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T147 22713-22717 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T148 22772-22781 Body_part denotes cytoplasm http://purl.org/sig/ont/fma/fma66835
T149 22858-22862 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T150 22883-22887 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T151 23071-23076 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T152 23129-23134 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T153 23228-23233 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 23304-23311 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T155 23358-23363 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 23656-23673 Body_part denotes cellular membrane http://purl.org/sig/ont/fma/fma63841
T157 23677-23689 Body_part denotes cytoskeleton http://purl.org/sig/ont/fma/fma63834
T158 23921-23926 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T159 23972-23977 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T160 24016-24021 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T161 24089-24093 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T162 24225-24230 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T163 24349-24352 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T164 24372-24377 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T165 24418-24422 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T166 24533-24538 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T167 24759-24764 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T168 24863-24871 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T169 24920-24925 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T170 25040-25048 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T171 25106-25111 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T172 25261-25269 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T173 25308-25316 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T174 25371-25376 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T175 25414-25419 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 25452-25460 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T177 25489-25496 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T178 25504-25511 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T179 25522-25529 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T180 25566-25574 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T181 25659-25664 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T182 25855-25859 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T183 26028-26036 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T184 26168-26174 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T185 26245-26251 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T186 26305-26313 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T187 26385-26393 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T188 26460-26468 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T189 26509-26514 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T190 26546-26553 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T191 26681-26689 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T192 26708-26713 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T193 26861-26868 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T194 27018-27025 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T195 27045-27055 Body_part denotes methionine http://purl.org/sig/ont/fma/fma82759
T196 27074-27081 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T197 27167-27174 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T198 27327-27329 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T199 27385-27392 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T200 27464-27471 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T201 27563-27574 Body_part denotes Nucleoporin http://purl.org/sig/ont/fma/fma67688
T202 27726-27729 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T203 27768-27771 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T204 27788-27795 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T205 27858-27861 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T206 27883-27899 Body_part denotes Collagen type IV http://purl.org/sig/ont/fma/fma63906
T207 27883-27891 Body_part denotes Collagen http://purl.org/sig/ont/fma/fma63891
T208 27958-27987 Body_part denotes glomerular basement membranes http://purl.org/sig/ont/fma/fma74274
T209 28425-28439 Body_part denotes Interleukin 13 http://purl.org/sig/ont/fma/fma264824
T210 28425-28436 Body_part denotes Interleukin http://purl.org/sig/ont/fma/fma86578
T211 28537-28545 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T212 28614-28617 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T213 28656-28665 Body_part denotes Prolactin http://purl.org/sig/ont/fma/fma83358
T214 28833-28836 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T215 28922-28929 Body_part denotes Tubulin http://purl.org/sig/ont/fma/fma67116
T216 28952-28960 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T217 28979-28984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T218 28990-29013 Body_part denotes low density lipoprotein http://purl.org/sig/ont/fma/fma63170
T219 29203-29206 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T220 29289-29292 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T221 29560-29566 Body_part denotes finger http://purl.org/sig/ont/fma/fma9666
T222 29717-29724 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T223 29741-29744 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T224 29872-29881 Body_part denotes Chromatin http://purl.org/sig/ont/fma/fma67526
T225 29980-29983 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T226 30104-30107 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T227 30264-30279 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T228 30275-30279 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T229 30294-30301 Body_part denotes Myocyte http://purl.org/sig/ont/fma/fma67328
T230 30361-30368 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T231 30514-30521 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T232 30563-30570 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T233 30571-30577 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T234 30578-30587 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T235 30692-30699 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T236 30716-30737 Body_part denotes Transmembrane protein http://purl.org/sig/ont/fma/fma67858
T237 30791-30795 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T238 30851-30853 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T239 30924-30931 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T240 30974-30982 Body_part denotes Cadherin http://purl.org/sig/ont/fma/fma61790
T241 30991-31004 Body_part denotes Ribosomal RNA http://purl.org/sig/ont/fma/fma67118
T242 31001-31004 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T243 31005-31012 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T244 31077-31081 Body_part denotes rRNA http://purl.org/sig/ont/fma/fma67118
T245 31083-31090 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T246 31133-31141 Body_part denotes tyrosine http://purl.org/sig/ont/fma/fma82768
T247 31183-31190 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T248 31191-31197 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T249 31198-31207 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T250 31349-31356 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T251 31420-31427 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T252 31428-31434 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T253 31435-31444 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T254 31505-31513 Body_part denotes Cysteine http://purl.org/sig/ont/fma/fma82751
T255 31674-31681 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T256 31682-31688 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T257 31689-31698 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T258 31738-31745 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T259 31746-31752 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T260 31753-31762 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T261 31802-31809 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T262 31862-31872 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T263 31897-31904 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T264 32122-32128 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T265 32129-32138 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T266 32139-32146 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T267 32215-32218 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T268 32248-32255 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T269 32300-32303 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T270 32424-32431 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T271 32495-32502 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T272 32720-32738 Body_part denotes Actin cytoskeleton http://purl.org/sig/ont/fma/fma84684
T273 32720-32725 Body_part denotes Actin http://purl.org/sig/ont/fma/fma67843
T274 32782-32793 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T275 32794-32801 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T276 32948-32955 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T277 32989-32996 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T278 33007-33015 Body_part denotes Cadherin http://purl.org/sig/ont/fma/fma61790
T279 33162-33170 Body_part denotes ribosome http://purl.org/sig/ont/fma/fma66867
T280 33182-33189 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T281 33263-33271 Body_part denotes ribosome http://purl.org/sig/ont/fma/fma66867
T282 33283-33290 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T283 33397-33404 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T284 33440-33447 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T285 33482-33489 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T286 33691-33698 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T287 33752-33759 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T288 33801-33804 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T289 33872-33878 Body_part denotes Serine http://purl.org/sig/ont/fma/fma82764
T290 33911-33918 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T291 33919-33931 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T292 33986-33998 Body_part denotes Glycoprotein http://purl.org/sig/ont/fma/fma62925
T293 34631-34636 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T294 34723-34726 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T295 34750-34755 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T296 34822-34826 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T297 34853-34861 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T298 34928-34933 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T299 34982-34987 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T300 35196-35204 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T301 35216-35221 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T302 35496-35501 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T303 35558-35565 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T304 35594-35599 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T305 35607-35612 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T306 35646-35653 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T307 35682-35687 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T308 35695-35700 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T309 36212-36216 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T310 36265-36270 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T311 36301-36306 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T312 36396-36400 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T313 36432-36435 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T314 36593-36598 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T315 36619-36623 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T316 36793-36798 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T317 36832-36837 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T318 37041-37049 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T319 37061-37066 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T320 37097-37102 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T321 37192-37196 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T322 37213-37218 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T323 37367-37372 Body_part denotes Actin http://purl.org/sig/ont/fma/fma67843
T324 37665-37670 Body_part denotes actin http://purl.org/sig/ont/fma/fma67843
T325 37903-37911 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T326 38052-38060 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T327 38129-38142 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T328 38510-38518 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T329 38610-38617 Body_part denotes synapse http://purl.org/sig/ont/fma/fma67408
T330 38651-38660 Body_part denotes organelle http://purl.org/sig/ont/fma/fma63832
T331 38666-38675 Body_part denotes cell part http://purl.org/sig/ont/fma/fma61764
T332 38666-38670 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T333 38752-38761 Body_part denotes organelle http://purl.org/sig/ont/fma/fma63832
T334 38766-38775 Body_part denotes cell part http://purl.org/sig/ont/fma/fma61764
T335 38766-38770 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T336 38821-38829 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T337 39150-39158 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T338 39181-39186 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T339 39266-39274 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T340 39280-39288 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T341 39551-39559 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T342 39602-39610 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T343 39712-39720 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T344 40207-40215 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T345 40334-40342 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T346 40395-40403 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T347 40438-40446 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T348 40498-40506 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T349 40528-40535 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T350 40596-40604 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T351 40685-40693 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T352 40715-40718 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T353 40750-40758 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T354 40780-40789 Body_part denotes chromatin http://purl.org/sig/ont/fma/fma67526
T355 40816-40824 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T356 40846-40858 Body_part denotes carbohydrate http://purl.org/sig/ont/fma/fma82737
T357 40891-40899 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T358 40972-40982 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T359 41009-41014 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T360 41054-41063 Body_part denotes ribosomal http://purl.org/sig/ont/fma/fma66867
T361 41091-41095 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T362 41201-41213 Body_part denotes cytoskeleton http://purl.org/sig/ont/fma/fma63834
T363 41234-41242 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T364 41385-41393 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T365 41508-41516 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T366 41539-41544 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T367 41706-41714 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T368 42034-42042 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T369 42107-42120 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T370 42122-42138 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T371 42421-42429 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T372 42692-42700 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T373 42912-42919 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T374 42957-42964 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T375 43486-43490 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T376 43491-43495 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T377 43504-43521 Body_part denotes glycosaminoglycan http://purl.org/sig/ont/fma/fma63011
T378 43558-43564 Body_part denotes oocyte http://purl.org/sig/ont/fma/fma18644
T379 43878-43886 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T380 43909-43914 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T381 44004-44012 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T382 44348-44356 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T383 44444-44452 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T384 44525-44533 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T385 44604-44612 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T386 44966-44973 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T387 44974-44981 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T388 45040-45047 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T389 45139-45146 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T390 45147-45154 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T391 45316-45323 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T392 45495-45503 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T393 45711-45715 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T394 45770-45778 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T395 45790-45798 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T396 46043-46051 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T397 46180-46184 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T398 46291-46299 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T399 46347-46354 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T400 46412-46417 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T401 46515-46522 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T402 46523-46530 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T403 46587-46595 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T404 46618-46623 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T405 46778-46785 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T406 46855-46863 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T407 47057-47062 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T408 47186-47194 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T409 47699-47706 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T410 47724-47729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T411 47855-47860 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T412 47879-47883 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T413 47931-47936 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T414 48025-48036 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T415 48117-48122 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T416 48373-48378 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T417 48395-48403 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T418 48442-48450 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T419 48524-48532 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T420 48597-48605 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T421 48791-48798 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T422 49008-49013 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T423 49100-49104 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T424 49194-49199 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T425 49403-49407 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T426 49515-49520 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T427 49897-49901 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T428 50063-50067 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T429 50105-50113 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T430 50236-50244 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T431 50338-50351 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T432 50374-50378 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T433 50396-50404 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T434 50578-50585 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T435 50620-50627 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T436 50693-50700 Body_part denotes synapse http://purl.org/sig/ont/fma/fma67408
T437 50734-50741 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T438 50756-50760 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T439 50799-50806 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T440 50918-50926 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T441 51288-51296 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T442 51304-51310 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T443 51416-51429 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T444 51446-51454 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T445 51633-51641 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T446 51756-51765 Body_part denotes chromatin http://purl.org/sig/ont/fma/fma67526
T447 51798-51806 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T448 52021-52029 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T449 52650-52658 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T450 52775-52783 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T451 52835-52848 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T452 52884-52892 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T453 52927-52943 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T454 52979-52987 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T455 53075-53083 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T456 53149-53156 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T457 53245-53252 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T458 53396-53409 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T459 53529-53532 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T460 53751-53764 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T461 53820-53836 Body_part denotes type IV collagen http://purl.org/sig/ont/fma/fma63906
T462 53981-53997 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T463 54017-54024 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T464 54053-54071 Body_part denotes basement membranes http://purl.org/sig/ont/fma/fma63872
T465 54142-54159 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T466 54154-54159 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T467 54183-54191 Body_part denotes integrin http://purl.org/sig/ont/fma/fma67222
T468 54426-54435 Body_part denotes cytosolic http://purl.org/sig/ont/fma/fma66836
T469 54522-54525 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T470 54866-54874 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T471 54980-54985 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T472 55002-55010 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T473 55285-55290 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T474 55484-55489 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T475 55523-55528 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T476 55794-55799 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T477 56164-56171 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T478 56262-56265 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T479 56443-56448 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T480 56772-56776 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T481 56919-56924 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T482 56937-56944 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T483 57623-57628 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T484 57830-57835 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T485 57960-57965 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T486 57995-57999 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T487 58620-58624 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T488 58842-58847 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T489 58947-58951 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T490 59102-59110 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T491 59135-59139 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T492 59206-59218 Body_part denotes nuclear pore http://purl.org/sig/ont/fma/fma63148
T493 59323-59339 Body_part denotes nuclear envelope http://purl.org/sig/ont/fma/fma63888
T494 59502-59506 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T495 59525-59528 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T496 59699-59702 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T497 59817-59820 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T498 60245-60248 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T499 60259-60262 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T500 60341-60344 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T501 60538-60543 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T502 60609-60613 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T503 60763-60768 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T504 61260-61265 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T505 61680-61685 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T506 61848-61858 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T507 62153-62158 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T508 62285-62290 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T509 62622-62629 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T510 62665-62670 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T511 62797-62805 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T512 62827-62835 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T513 62879-62884 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T514 63051-63067 Body_part denotes digestive system http://purl.org/sig/ont/fma/fma7152
T515 63069-63082 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T516 63161-63165 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T517 63425-63430 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T518 63882-63890 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T519 63938-63943 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T520 64013-64021 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T521 64059-64064 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T522 64153-64161 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T523 64255-64263 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T524 64351-64359 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T525 64450-64458 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T526 64551-64559 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 266-282 Body_part denotes small intestinal http://purl.obolibrary.org/obo/UBERON_0002108
T2 1359-1372 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T3 1374-1390 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T4 2601-2616 Body_part denotes small intestine http://purl.obolibrary.org/obo/UBERON_0002108
T5 2607-2616 Body_part denotes intestine http://purl.obolibrary.org/obo/UBERON_0000160
T6 2644-2651 Body_part denotes jejunum http://purl.obolibrary.org/obo/UBERON_0002115
T7 2656-2661 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T8 2686-2692 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T9 2715-2731 Body_part denotes small intestinal http://purl.obolibrary.org/obo/UBERON_0002108
T10 2937-2953 Body_part denotes small intestinal http://purl.obolibrary.org/obo/UBERON_0002108
T11 3082-3089 Body_part denotes jejunum http://purl.obolibrary.org/obo/UBERON_0002115
T12 4008-4012 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T13 5802-5806 Body_part denotes foot http://purl.obolibrary.org/obo/UBERON_0002387
T14 5811-5816 Body_part denotes mouth http://purl.obolibrary.org/obo/UBERON_0000165
T15 6613-6619 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T16 6698-6704 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T17 7043-7048 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T18 8180-8185 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T19 8935-8940 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T20 13528-13537 Body_part denotes capillary http://purl.obolibrary.org/obo/UBERON_0001982
T21 19744-19748 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913
T22 24155-24160 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T23 24468-24473 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T24 27958-27987 Body_part denotes glomerular basement membranes http://purl.obolibrary.org/obo/UBERON_0005777
T25 29560-29566 Body_part denotes finger http://purl.obolibrary.org/obo/UBERON_0002389
T26 38129-38142 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T27 38666-38675 Body_part denotes cell part http://purl.obolibrary.org/obo/UBERON_0000470
T28 38766-38775 Body_part denotes cell part http://purl.obolibrary.org/obo/UBERON_0000470
T29 42107-42120 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T30 42122-42138 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T31 43491-43495 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T32 50338-50351 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T33 51311-51316 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T34 51416-51429 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T35 52835-52848 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T36 52927-52943 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T37 53396-53409 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T38 53751-53764 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T39 53981-53997 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T40 54124-54128 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T41 59214-59218 Body_part denotes pore http://purl.obolibrary.org/obo/UBERON_0008915
T42 63051-63067 Body_part denotes digestive system http://purl.obolibrary.org/obo/UBERON_0001007
T43 63069-63082 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 248-256 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T2 345-354 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T3 2013-2031 Disease denotes diarrheal diseases http://purl.obolibrary.org/obo/MONDO_0001673
T4 2062-2071 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 2331-2339 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T6 2424-2433 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 2853-2862 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 3531-3539 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T9 3574-3589 Disease denotes gastroenteritis http://purl.obolibrary.org/obo/MONDO_0002269
T10 3699-3708 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T11 4825-4841 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T12 5802-5824 Disease denotes foot-and-mouth disease http://purl.obolibrary.org/obo/MONDO_0005765
T13 5811-5824 Disease denotes mouth disease http://purl.obolibrary.org/obo/MONDO_0006858
T14 5879-5900 Disease denotes classical swine fever http://purl.obolibrary.org/obo/MONDO_0025087
T15 6292-6301 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T16 6463-6466 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T17 6590-6598 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T18 6713-6723 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T19 7912-7919 Disease denotes sterile http://purl.obolibrary.org/obo/MONDO_0005047
T20 8015-8018 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T21 8055-8064 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T22 8164-8171 Disease denotes sterile http://purl.obolibrary.org/obo/MONDO_0005047
T23 16207-16209 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T25 21483-21492 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 22046-22055 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T27 22144-22153 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T28 22584-22593 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T29 24046-24049 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T30 24578-24593 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T31 24584-24593 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T32 24786-24795 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T33 24827-24842 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T34 24833-24842 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 25575-25578 Disease denotes NS6 http://purl.obolibrary.org/obo/MONDO_0013186
T36 25583-25586 Disease denotes NS7 http://purl.obolibrary.org/obo/MONDO_0013379
T37 26536-26545 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T38 26596-26605 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T39 27989-27992 Disease denotes GBM http://purl.obolibrary.org/obo/MONDO_0018177
T40 29144-29160 Disease denotes Myeloid leukemia http://purl.obolibrary.org/obo/MONDO_0004643
T41 29152-29160 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059
T42 30784-30790 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T43 32487-32494 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T44 35361-35370 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T45 35756-35765 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T46 36282-36291 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T47 36353-36356 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T48 37078-37087 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T49 37149-37152 Disease denotes CHN http://purl.obolibrary.org/obo/MONDO_0011527
T50 38019-38021 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T52 38804-38806 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T54 39198-39207 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T55 39407-39409 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T57 41556-41565 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 42059-42084 Disease denotes viral infectious diseases http://purl.obolibrary.org/obo/MONDO_0005108
T59 42065-42075 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T60 42122-42150 Disease denotes digestive system and cancers http://purl.obolibrary.org/obo/MONDO_0002516
T61 42657-42663 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T62 43290-43299 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T63 43301-43331 Disease denotes human papillomavirus infection http://purl.obolibrary.org/obo/MONDO_0005161
T64 43322-43331 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T65 43416-43422 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T66 43424-43433 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T67 43437-43444 Disease denotes measles http://purl.obolibrary.org/obo/MONDO_0004619
T68 43480-43502 Disease denotes small cell lung cancer http://purl.obolibrary.org/obo/MONDO_0008433
T69 43491-43502 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T70 43496-43502 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T71 43753-43773 Disease denotes diseases, metabolism http://purl.obolibrary.org/obo/MONDO_0005066
T72 43926-43935 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T73 44196-44198 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T74 46097-46106 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T75 46391-46400 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T76 46635-46644 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T77 47262-47277 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T78 47268-47277 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T79 47528-47544 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T80 47735-47744 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T81 47986-47995 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T82 48071-48080 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T83 48281-48290 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T84 48578-48581 Disease denotes NS6 http://purl.obolibrary.org/obo/MONDO_0013186
T85 48583-48586 Disease denotes NS7 http://purl.obolibrary.org/obo/MONDO_0013379
T86 49216-49225 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T87 51090-51092 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T89 52589-52613 Disease denotes viral infectious disease http://purl.obolibrary.org/obo/MONDO_0005108
T90 52595-52613 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T91 53033-53039 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T92 53366-53391 Disease denotes viral infectious diseases http://purl.obolibrary.org/obo/MONDO_0005108
T93 53372-53382 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T94 53721-53746 Disease denotes viral infectious diseases http://purl.obolibrary.org/obo/MONDO_0005108
T95 53727-53737 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T96 53934-53958 Disease denotes viral infectious disease http://purl.obolibrary.org/obo/MONDO_0005108
T97 53940-53958 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T98 53981-54010 Disease denotes digestive system, and cancers http://purl.obolibrary.org/obo/MONDO_0002516
T99 54258-54263 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T100 55088-55104 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T101 55187-55196 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T102 55296-55305 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T103 56172-56175 Disease denotes NS6 http://purl.obolibrary.org/obo/MONDO_0013186
T104 57108-57116 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T105 57121-57127 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T106 57776-57785 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T107 57919-57928 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T108 58099-58108 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T109 59945-59951 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T110 59953-59976 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T111 60103-60112 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T112 60122-60128 Disease denotes dengue http://purl.obolibrary.org/obo/MONDO_0005502
T113 60164-60180 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T114 60278-60287 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T115 60780-60789 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T116 60983-61030 Disease denotes severe acute respiratory syndrome coronavirus-2 http://purl.obolibrary.org/obo/MONDO_0100096
T117 60983-61016 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T118 61032-61040 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 61067-61091 Disease denotes Coronavirus Disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T120 61093-61101 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 61280-61288 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T122 61291-61300 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T123 61404-61412 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 61415-61424 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T125 61585-61593 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T126 61701-61709 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T127 61712-61721 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T128 61891-61906 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T129 61897-61906 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T130 62029-62037 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 62132-62140 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T132 62260-62268 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 43-53 http://purl.obolibrary.org/obo/UBERON_0000160 denotes Intestinal
T2 43-53 http://www.ebi.ac.uk/efo/EFO_0000834 denotes Intestinal
T3 54-64 http://purl.obolibrary.org/obo/CL_0000066 denotes Epithelial
T4 65-70 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T5 130-132 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T6 133-135 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T7 136-138 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T8 266-282 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestinal
T9 283-293 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T10 294-299 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T11 330-335 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12 433-441 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeling
T13 501-503 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T14 504-506 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T15 507-509 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T16 614-619 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17 621-622 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T18 1250-1251 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 1331-1340 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T20 1359-1372 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T21 1374-1390 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T22 1374-1390 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T23 1392-1398 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T24 1465-1469 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T25 1476-1485 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T26 1568-1573 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T27 1726-1729 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T28 1730-1731 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 1931-1932 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 2130-2135 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T31 2136-2139 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T32 2456-2459 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T33 2538-2541 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T34 2601-2616 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestine
T35 2644-2651 http://purl.obolibrary.org/obo/UBERON_0002115 denotes jejunum
T36 2656-2661 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T37 2686-2692 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T38 2715-2731 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestinal
T39 2732-2742 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T40 2743-2748 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T41 2937-2953 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestinal
T42 3038-3047 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T43 3082-3089 http://purl.obolibrary.org/obo/UBERON_0002115 denotes jejunum
T44 3093-3094 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 3123-3126 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T46 3178-3188 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T47 3178-3188 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T48 3197-3207 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T49 3208-3213 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T50 3214-3216 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T51 3293-3303 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T52 3325-3330 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T53 3440-3450 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T54 3451-3456 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T55 3477-3484 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T56 3540-3545 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T57 3590-3595 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T58 3662-3667 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T59 3723-3724 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T60 3899-3900 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 3901-3906 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T62 3915-3916 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 3922-3926 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T64 3966-3970 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T65 3979-3984 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T66 4027-4032 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T67 4119-4124 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T68 4151-4156 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T69 4220-4225 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T70 4250-4255 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T71 4256-4260 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T72 4366-4367 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 4420-4431 http://purl.obolibrary.org/obo/CLO_0052500 denotes PK-15 cells
T74 4518-4523 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T75 4612-4618 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T76 4725-4730 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T77 4912-4917 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T78 4918-4920 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T79 5079-5087 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeling
T80 5106-5110 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T81 5186-5188 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T82 5193-5198 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T83 5333-5335 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T84 5336-5338 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T85 5339-5341 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T86 5352-5355 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T87 5530-5531 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 5673-5676 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T89 5735-5740 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T90 5791-5793 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T91 5811-5816 http://www.ebi.ac.uk/efo/EFO_0000825 denotes mouth
T92 5825-5830 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T93 5901-5906 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T94 5942-5943 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 5998-6003 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T96 6050-6051 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 6117-6120 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T98 6152-6157 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T99 6210-6212 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T100 6213-6215 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T101 6216-6218 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T102 6265-6270 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T103 6424-6429 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T104 6431-6436 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T105 6467-6469 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T106 6553-6563 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T107 6553-6563 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T108 6576-6577 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 6613-6619 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T110 6613-6619 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T111 6613-6619 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T112 6620-6633 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T113 6676-6677 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T114 6754-6759 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T115 6781-6786 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T116 6908-6913 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T117 7090-7097 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T118 7153-7155 http://purl.obolibrary.org/obo/CLO_0009141 denotes St
T119 7153-7155 http://purl.obolibrary.org/obo/CLO_0050980 denotes St
T120 7164-7166 http://purl.obolibrary.org/obo/CLO_0007815 denotes MO
T121 7263-7268 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T122 7295-7296 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 7482-7487 http://purl.obolibrary.org/obo/CLO_0007836 denotes Mouse
T124 7506-7511 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T125 7653-7657 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T126 7759-7763 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T127 7829-7834 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T128 7855-7860 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T129 8019-8021 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T130 8037-8038 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 8085-8093 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T132 8136-8141 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T133 8268-8273 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T134 8407-8412 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T135 8639-8644 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T136 8690-8691 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 8813-8818 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T138 8858-8860 http://purl.obolibrary.org/obo/CLO_0009877 denotes NY
T139 9036-9038 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T140 9054-9059 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T141 9195-9197 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T142 9221-9226 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T143 9352-9360 http://purl.obolibrary.org/obo/CLO_0008190 denotes per cell
T144 9368-9369 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T145 9370-9372 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T146 9413-9418 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T147 9519-9524 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T148 9667-9671 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T149 9730-9735 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T150 9799-9804 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T151 9927-9935 http://purl.obolibrary.org/obo/CLO_0007225 denotes Labeling
T152 10003-10008 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T153 10039-10044 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T154 10126-10130 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T155 10297-10301 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T156 10466-10470 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T157 10615-10619 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4 °C
T158 10750-10751 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 10988-10990 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T160 10991-10993 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T161 10994-10996 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T162 11035-11043 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeling
T163 11141-11142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 11192-11193 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T165 11380-11381 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 11573-11574 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 11655-11659 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4 °C
T168 11893-11901 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T169 11994-12002 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T170 12013-12020 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T171 12221-12228 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T172 12251-12254 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T173 12351-12358 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T174 12370-12373 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T175 12396-12399 http://purl.obolibrary.org/obo/CLO_0001053 denotes 121
T176 12409-12416 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T177 12648-12649 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T178 12686-12687 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T179 12836-12837 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T180 12872-12874 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T181 12875-12877 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T182 12878-12880 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T183 12890-12892 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T184 12893-12895 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T185 12896-12898 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T186 12915-12922 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T187 12923-12931 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T188 12955-12956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T189 13124-13131 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T190 13132-13140 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T191 13146-13147 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 13207-13215 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T193 13252-13253 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 13318-13319 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T195 13394-13395 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T196 13637-13638 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T197 13711-13713 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T198 13718-13720 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T199 13721-13723 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T200 13725-13726 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T201 13732-13734 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T202 13874-13875 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T203 13908-13910 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T204 14011-14013 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T205 14014-14016 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T206 14093-14100 http://purl.obolibrary.org/obo/CLO_0001040 denotes 1 × 105
T207 14121-14123 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T208 14152-14154 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T209 14232-14234 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T210 14262-14264 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T211 14265-14267 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T212 14893-14903 http://purl.obolibrary.org/obo/OBI_0000968 denotes instrument
T213 15248-15250 http://www.ebi.ac.uk/efo/EFO_0000265 denotes Da
T214 15315-15317 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T215 15358-15365 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T216 15444-15445 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 15484-15491 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T218 15527-15531 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T219 15696-15701 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T220 15726-15727 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T221 15759-15762 http://purl.obolibrary.org/obo/CLO_0001547 denotes a p
T222 15976-15981 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T223 16000-16004 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T224 16158-16176 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular component
T225 16178-16180 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T226 16346-16350 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T227 16367-16370 http://purl.obolibrary.org/obo/CLO_0001547 denotes a p
T228 16615-16620 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Genes
T229 16848-16849 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T230 16867-16875 http://purl.obolibrary.org/obo/CLO_0001040 denotes 1 × 10–5
T231 17033-17037 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T232 17648-17653 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T233 17814-17815 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T234 17958-17959 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T235 18049-18050 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 18064-18068 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T237 18188-18193 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T238 18629-18633 http://purl.obolibrary.org/obo/CLO_0001564 denotes a 20
T239 18629-18633 http://purl.obolibrary.org/obo/CLO_0050194 denotes a 20
T240 18850-18851 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T241 19144-19148 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T242 19431-19436 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T243 19576-19585 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T244 19622-19623 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T245 19657-19661 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T246 19696-19705 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T247 19728-19731 http://purl.obolibrary.org/obo/CLO_0050644 denotes w/v
T248 19762-19766 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4 °C
T249 19938-19947 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T250 20081-20090 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T251 20211-20212 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T252 20333-20335 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T253 20336-20338 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T254 20339-20341 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T255 20751-20753 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T256 20928-20932 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T257 21018-21019 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T258 21249-21254 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T259 21343-21347 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T260 21367-21369 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T261 21463-21464 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T262 21504-21509 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T263 21535-21540 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T264 21636-21641 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T265 21650-21655 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T266 21674-21679 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T267 22163-22168 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T268 22253-22257 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4, 8
T269 22271-22273 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T270 22294-22298 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T271 22418-22423 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T272 22451-22456 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T273 22483-22488 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T274 22677-22679 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T275 22713-22717 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T276 22858-22862 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T277 22883-22887 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T278 23055-23057 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T279 23055-23057 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T280 23063-23076 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T281 23077-23079 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T282 23094-23096 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T283 23129-23134 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T284 23228-23233 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T285 23260-23261 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T286 23358-23363 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T287 23455-23460 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T288 23475-23476 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T289 23528-23529 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T290 23665-23673 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T291 23744-23745 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T292 23765-23767 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T293 23921-23926 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T294 23972-23977 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T295 23980-23981 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T296 24016-24021 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T297 24050-24052 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T298 24089-24093 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T299 24117-24121 http://purl.obolibrary.org/obo/CLO_0001382 denotes 4, 8
T300 24135-24137 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T301 24171-24177 http://purl.obolibrary.org/obo/PR_000010213 denotes m. (B)
T302 24225-24230 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T303 24326-24333 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T304 24334-24338 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T305 24372-24377 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T306 24398-24399 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T307 24418-24422 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T308 24533-24538 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T309 24608-24613 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T310 24759-24764 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T311 24920-24925 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T312 24998-25000 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T313 25001-25003 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T314 25004-25006 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T315 25106-25111 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T316 25142-25144 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T317 25371-25376 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T318 25414-25419 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T319 25513-25521 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T320 25575-25578 http://purl.obolibrary.org/obo/OGG_3000004893 denotes NS6
T321 25583-25586 http://purl.obolibrary.org/obo/CLO_0008201 denotes NS7
T322 25607-25609 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T323 25607-25609 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T324 25659-25664 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T325 25855-25859 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T326 26121-26123 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T327 26239-26244 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T328 26354-26355 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T329 26509-26514 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T330 26616-26624 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T331 26708-26713 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T332 26758-26760 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T333 26930-26935 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T334 27142-27147 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T335 27280-27285 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T336 27472-27475 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T337 27514-27522 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T338 27545-27562 http://purl.obolibrary.org/obo/PR_000024990 denotes type I interferon
T339 27759-27767 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T340 27816-27817 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T341 27874-27882 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T342 27883-27891 http://purl.obolibrary.org/obo/CHEBI_3815 denotes Collagen
T343 27969-27987 http://purl.obolibrary.org/obo/UBERON_0005769 denotes basement membranes
T344 27989-27992 http://purl.obolibrary.org/obo/CLO_0003456 denotes GBM
T345 28006-28008 http://purl.obolibrary.org/obo/CLO_0050160 denotes T2
T346 28053-28055 http://purl.obolibrary.org/obo/CLO_0050160 denotes T2
T347 28056-28064 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T348 28349-28357 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T349 28506-28512 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T350 28524-28532 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T351 28555-28563 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T352 28564-28567 http://purl.obolibrary.org/obo/OGG_3000002353 denotes FOS
T353 28647-28655 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T354 28656-28665 http://purl.obolibrary.org/obo/PR_000013246 denotes Prolactin
T355 28732-28741 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T356 28742-28750 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T357 28755-28765 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T358 28854-28862 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T359 28979-28984 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T360 29310-29318 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T361 29574-29576 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T362 29732-29740 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T363 29804-29812 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T364 29863-29871 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T365 29908-29909 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T366 30006-30007 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T367 30092-30100 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T368 30264-30274 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T369 30275-30279 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T370 30294-30301 http://purl.obolibrary.org/obo/CL_0000187 denotes Myocyte
T371 30382-30390 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T372 30487-30495 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T373 30504-30513 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T374 30595-30603 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T375 30707-30715 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T376 30791-30795 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T377 30894-30902 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T378 30974-30982 http://purl.obolibrary.org/obo/PR_000001327 denotes Cadherin
T379 31118-31126 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T380 31215-31223 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T381 31452-31460 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T382 31543-31551 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T383 31770-31778 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T384 31852-31860 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T385 31995-32004 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T386 32059-32061 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T387 32101-32109 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T388 32206-32214 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T389 32393-32401 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T390 32739-32751 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T391 32845-32853 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T392 32939-32947 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T393 33007-33015 http://purl.obolibrary.org/obo/PR_000001327 denotes Cadherin
T394 33144-33152 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T395 33295-33297 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T396 33308-33309 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T397 33507-33515 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T398 33617-33625 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T399 33626-33632 http://purl.obolibrary.org/obo/SO_0000418 denotes Signal
T400 33633-33640 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T401 33716-33724 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T402 33898-33906 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T403 34019-34027 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T404 34136-34138 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T405 34292-34295 http://purl.obolibrary.org/obo/CLO_0051142 denotes Rho
T406 34456-34458 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T407 34459-34461 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T408 34462-34464 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T409 34631-34636 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T410 34750-34755 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T411 34805-34807 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T412 34928-34933 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T413 34982-34987 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T414 35044-35046 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T415 35216-35221 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T416 35294-35300 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T417 35496-35501 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T418 35607-35612 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T419 35695-35700 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T420 35733-35734 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T421 35806-35815 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T422 35890-35892 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T423 35890-35892 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T424 35949-35951 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T425 36106-36108 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T426 36109-36111 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T427 36112-36114 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T428 36150-36151 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T429 36265-36270 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T430 36301-36306 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T431 36357-36359 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T432 36396-36400 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T433 36619-36623 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T434 36710-36714 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T435 36729-36730 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T436 36832-36837 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T437 36918-36920 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T438 36958-36959 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T439 37061-37066 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T440 37097-37102 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T441 37153-37155 http://purl.obolibrary.org/obo/CLO_0003788 denotes HN
T442 37192-37196 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T443 37213-37218 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T444 37290-37295 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T445 37738-37740 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T446 37778-37779 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T447 37970-37988 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular component
T448 37990-37992 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T449 38129-38142 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T450 38493-38495 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T451 38581-38600 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T452 38641-38649 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T453 38666-38670 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T454 38742-38750 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T455 38766-38770 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T456 38920-38928 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T457 38942-38950 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T458 38968-38976 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T459 39181-39186 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T460 39210-39211 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T461 39358-39376 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular component
T462 39378-39380 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T463 39648-39649 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T464 39817-39818 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T465 40046-40050 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T466 40281-40283 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T467 40464-40470 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T468 41091-41095 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T469 41101-41109 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T470 41539-41544 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T471 41799-41808 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T472 41907-41909 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T473 42086-42092 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T474 42107-42120 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T475 42122-42138 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T476 42122-42138 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T477 42267-42272 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T478 42396-42398 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T479 42521-42530 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T480 42585-42594 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T481 42613-42622 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T482 42790-42799 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T483 42851-42860 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T484 43004-43006 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T485 43123-43132 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T486 43264-43273 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T487 43301-43306 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T488 43342-43351 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T489 43434-43435 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T490 43446-43448 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T491 43486-43490 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T492 43491-43495 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T493 43491-43495 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T494 43589-43598 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T495 43626-43635 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T496 43747-43752 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T497 43909-43914 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T498 43938-43939 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T499 44180-44185 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T500 44307-44309 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T501 44376-44377 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T502 44714-44715 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T503 44942-44946 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T504 45310-45311 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T505 45711-45715 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T506 45726-45745 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T507 46180-46184 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T508 46412-46417 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T509 46459-46460 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T510 46618-46623 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T511 46701-46702 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T512 46776-46777 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T513 47057-47062 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T514 47067-47074 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T515 47168-47173 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T516 47284-47285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T517 47414-47416 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T518 47610-47612 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T519 47642-47645 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T520 47646-47653 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T521 47724-47729 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T522 47790-47792 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T523 47793-47795 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T524 47796-47798 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T525 47855-47860 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T526 47879-47889 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T527 47900-47902 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T528 47900-47902 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T529 47904-47907 http://purl.obolibrary.org/obo/CLO_0050167 denotes LLC
T530 47908-47911 http://purl.obolibrary.org/obo/CLO_0050105 denotes PK1
T531 47913-47918 http://purl.obolibrary.org/obo/CLO_0050908 denotes PK-15
T532 47924-47930 http://purl.obolibrary.org/obo/CLO_0006963 denotes IPI-2I
T533 47931-47936 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T534 48117-48122 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T535 48312-48313 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T536 48373-48378 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T537 48554-48562 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T538 48578-48581 http://purl.obolibrary.org/obo/OGG_3000004893 denotes NS6
T539 48583-48586 http://purl.obolibrary.org/obo/CLO_0008201 denotes NS7
T540 48934-48936 http://purl.obolibrary.org/obo/CLO_0002861 denotes E3
T541 48997-49007 http://purl.obolibrary.org/obo/NCBITaxon_2759 denotes eukaryotic
T542 49008-49013 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T543 49100-49104 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T544 49194-49199 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T545 49335-49336 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T546 49479-49488 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T547 49515-49520 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T548 49549-49554 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T549 49897-49901 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T550 49942-49943 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T551 50053-50058 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T552 50063-50067 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T553 50088-50097 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T554 50088-50097 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T555 50098-50100 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T556 50202-50219 http://purl.obolibrary.org/obo/PR_000024990 denotes type I interferon
T557 50259-50262 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T558 50338-50351 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T559 50374-50378 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T560 50670-50672 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T561 50756-50760 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T562 50839-50841 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T563 51010-51018 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T564 51032-51040 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T565 51055-51063 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T566 51158-51159 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T567 51225-51226 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T568 51416-51429 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T569 51558-51564 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T570 52261-52270 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T571 52515-52524 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T572 52701-52704 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T573 52721-52727 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T574 52835-52848 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T575 52927-52943 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T576 52927-52943 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T577 52997-52999 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T578 53186-53195 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T579 53227-53228 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T580 53309-53311 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T581 53347-53356 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T582 53396-53409 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T583 53751-53764 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T584 53765-53774 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T585 53828-53836 http://purl.obolibrary.org/obo/CHEBI_3815 denotes collagen
T586 53904-53913 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T587 53960-53966 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T588 53981-53997 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T589 53981-53997 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T590 54053-54071 http://purl.obolibrary.org/obo/UBERON_0005769 denotes basement membranes
T591 54124-54128 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T592 54142-54159 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T593 54210-54211 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T594 54301-54310 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T595 54380-54389 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T596 54587-54595 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T597 54607-54616 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T598 54723-54731 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T599 54915-54918 http://purl.obolibrary.org/obo/CLO_0009915 denotes Mx1
T600 54980-54985 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T601 55240-55249 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T602 55264-55273 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T603 55285-55290 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T604 55346-55347 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T605 55434-55443 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T606 55456-55465 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T607 55484-55489 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T608 55503-55504 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T609 55523-55528 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T610 55530-55540 http://purl.obolibrary.org/obo/CLO_0008447 denotes PK-15, was
T611 55530-55540 http://purl.obolibrary.org/obo/CLO_0008448 denotes PK-15, was
T612 55530-55535 http://purl.obolibrary.org/obo/CLO_0050908 denotes PK-15
T613 55614-55617 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T614 55786-55799 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T615 55879-55880 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T616 55939-55947 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T617 56044-56050 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T618 56066-56075 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T619 56122-56130 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T620 56172-56175 http://purl.obolibrary.org/obo/OGG_3000004893 denotes NS6
T621 56319-56328 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T622 56358-56367 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T623 56407-56416 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T624 56443-56448 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T625 56516-56525 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T626 56587-56588 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T627 56676-56685 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activated
T628 56772-56776 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T629 56829-56838 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T630 56994-57006 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T631 57041-57044 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T632 57162-57171 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T633 57338-57339 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T634 57361-57370 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T635 57530-57539 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T636 57623-57628 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T637 57683-57693 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T638 57720-57729 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T639 57799-57808 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T640 57830-57835 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T641 57875-57876 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T642 57952-57965 http://purl.obolibrary.org/obo/CLO_0052497 denotes LLC-PK1 cells
T643 57966-57968 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T644 57983-57984 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T645 57995-58004 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T646 58287-58296 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T647 58611-58624 http://purl.obolibrary.org/obo/CLO_0053408 denotes AKT2 and cell
T648 58631-58640 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T649 58788-58797 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T650 58842-58847 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T651 58870-58879 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T652 58934-58939 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T653 58947-58951 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T654 58958-58967 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T655 59135-59139 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T656 59146-59155 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T657 59421-59431 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T658 59437-59440 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T659 59502-59506 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T660 59617-59618 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T661 59664-59674 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T662 60018-60021 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T663 60086-60093 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T664 60113-60114 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T665 60115-60120 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T666 60129-60134 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T667 60136-60141 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T668 60158-60163 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T669 60181-60186 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T670 60288-60289 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T671 60290-60295 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T672 60473-60478 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T673 60502-60507 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T674 60538-60543 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T675 60673-60678 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T676 60763-60768 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T677 61116-61119 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T678 61126-61127 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T679 61255-61259 http://purl.obolibrary.org/obo/CLO_0009989 denotes Huh7
T680 61260-61265 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T681 61344-61353 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T682 61514-61523 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T683 61673-61679 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T684 61673-61679 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T685 61673-61679 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T686 61673-61679 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T687 61680-61685 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T688 61937-61943 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T689 62146-62152 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T690 62146-62152 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T691 62146-62152 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T692 62146-62152 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T693 62153-62158 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T694 62285-62290 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T695 62327-62336 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T696 62665-62670 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T697 62677-62678 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T698 62742-62744 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T699 62745-62747 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T700 62748-62750 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T701 62752-62753 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T702 62879-62884 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T703 62942-62943 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T704 63023-63032 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T705 63051-63067 http://purl.obolibrary.org/obo/UBERON_0001007 denotes digestive system
T706 63051-63067 http://www.ebi.ac.uk/efo/EFO_0000793 denotes digestive system
T707 63069-63082 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T708 63084-63090 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T709 63161-63165 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T710 63172-63181 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T711 63425-63430 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T712 63600-63602 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T713 63685-63687 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T714 63688-63690 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T715 63691-63693 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T716 63735-63737 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T717 63735-63737 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T718 63778-63787 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T719 63862-63864 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T720 63866-63867 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T721 63938-63943 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T722 63964-63966 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T723 63967-63969 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T724 64003-64005 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T725 64003-64005 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T726 64059-64064 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T727 64290-64292 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T728 65123-65125 http://purl.obolibrary.org/obo/CL_0000453 denotes LC
T729 65126-65128 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T730 65129-65131 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T731 65607-65611 http://purl.obolibrary.org/obo/CLO_0002199 denotes CARS
T732 65612-65614 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 130-132 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T2 133-135 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T3 136-138 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T4 501-503 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T5 504-506 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T6 507-509 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T7 572-580 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T8 687-695 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T9 960-970 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T10 979-986 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T11 4420-4422 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T12 5091-5102 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T13 5091-5096 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T14 5097-5102 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T15 5193-5198 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T16 5333-5335 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T17 5336-5338 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T18 5339-5341 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T19 5632-5640 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T20 6210-6212 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T21 6213-6215 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T22 6216-6218 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T23 7090-7097 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T24 7128-7136 Chemical denotes selenium http://purl.obolibrary.org/obo/CHEBI_27568
T25 7183-7193 Chemical denotes penicillin http://purl.obolibrary.org/obo/CHEBI_17334|http://purl.obolibrary.org/obo/CHEBI_51356
T27 7208-7220 Chemical denotes streptomycin http://purl.obolibrary.org/obo/CHEBI_17076|http://purl.obolibrary.org/obo/CHEBI_58007
T29 7308-7311 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T30 7358-7360 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T33 7442-7449 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34 7603-7605 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T37 7732-7747 Chemical denotes Alexa Fluor 488 http://purl.obolibrary.org/obo/CHEBI_52661
T38 7738-7743 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T39 7920-7929 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T43 8858-8860 Chemical denotes NY http://purl.obolibrary.org/obo/CHEBI_73427
T44 9404-9407 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T45 9451-9458 Chemical denotes ethanol http://purl.obolibrary.org/obo/CHEBI_16236
T46 9640-9655 Chemical denotes Alexa Fluor 488 http://purl.obolibrary.org/obo/CHEBI_52661
T47 9646-9651 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T48 9886-9893 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T49 10162-10167 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T50 10363-10369 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T51 10412-10415 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T52 10421-10425 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T53 10430-10449 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T55 10439-10449 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T56 10682-10690 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T57 10713-10720 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58 10763-10770 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T59 10811-10813 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T61 10840-10848 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T62 10988-10990 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T63 10991-10993 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T64 10994-10996 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T65 11064-11071 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T66 11116-11124 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T67 11184-11190 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T68 11226-11230 Chemical denotes tris http://purl.obolibrary.org/obo/CHEBI_9754
T69 11232-11246 Chemical denotes 2-carboxyethyl http://purl.obolibrary.org/obo/CHEBI_50329
T70 11248-11257 Chemical denotes phosphine http://purl.obolibrary.org/obo/CHEBI_30278|http://purl.obolibrary.org/obo/CHEBI_35883
T72 11259-11263 Chemical denotes TCEP http://purl.obolibrary.org/obo/CHEBI_63213
T73 11283-11290 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T74 11420-11427 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T75 11428-11436 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T76 11528-11535 Chemical denotes acetone http://purl.obolibrary.org/obo/CHEBI_15347
T77 11553-11560 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T78 11561-11569 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T79 11776-11783 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T80 11893-11901 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T81 11994-12002 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T82 12035-12043 Chemical denotes reagents http://purl.obolibrary.org/obo/CHEBI_33893
T83 12433-12438 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T84 12589-12591 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T87 12718-12723 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T88 12776-12781 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T89 12872-12874 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T90 12875-12877 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T91 12878-12880 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T92 12890-12892 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T93 12893-12895 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T94 12896-12898 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T95 12923-12931 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T96 13132-13140 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T97 13207-13215 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T98 13342-13353 Chemical denotes formic acid http://purl.obolibrary.org/obo/CHEBI_30751
T99 13349-13353 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T100 13367-13379 Chemical denotes acetonitrile http://purl.obolibrary.org/obo/CHEBI_38472
T101 13418-13429 Chemical denotes formic acid http://purl.obolibrary.org/obo/CHEBI_30751
T102 13425-13429 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T103 13444-13456 Chemical denotes acetonitrile http://purl.obolibrary.org/obo/CHEBI_38472
T104 13473-13476 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T105 13711-13713 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T106 13718-13720 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T107 13721-13723 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T108 13732-13734 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T109 13865-13869 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T110 13884-13887 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T111 13926-13930 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T112 14011-14013 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T113 14014-14016 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T114 14101-14105 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T115 14232-14234 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T116 14262-14264 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T117 14265-14267 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T118 14921-14929 Chemical denotes cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T119 15027-15034 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T120 15315-15317 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T121 15358-15365 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T122 15370-15377 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T123 15484-15491 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T124 15496-15503 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T125 15646-15654 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T126 15712-15720 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T127 16153-16155 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T128 16178-16180 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T129 16207-16209 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T130 16431-16438 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T131 17136-17143 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T132 17144-17151 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T133 18774-18779 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T134 19276-19283 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T135 19364-19372 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T136 19462-19469 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T137 19500-19503 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T138 19543-19568 Chemical denotes poly(vinylidene fluoride) http://purl.obolibrary.org/obo/CHEBI_53250
T139 19548-19558 Chemical denotes vinylidene http://purl.obolibrary.org/obo/CHEBI_29854
T140 19559-19567 Chemical denotes fluoride http://purl.obolibrary.org/obo/CHEBI_17051
T141 19607-19609 Chemical denotes MA http://purl.obolibrary.org/obo/CHEBI_474859|http://purl.obolibrary.org/obo/CHEBI_73610|http://purl.obolibrary.org/obo/CHEBI_90325
T144 20060-20067 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T145 20333-20335 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T146 20336-20338 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T147 20339-20341 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T148 20751-20753 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T149 20876-20878 Chemical denotes SD http://purl.obolibrary.org/obo/CHEBI_74807
T150 20981-20983 Chemical denotes La http://purl.obolibrary.org/obo/CHEBI_33336
T151 21383-21389 Chemical denotes formal http://purl.obolibrary.org/obo/CHEBI_48341
T152 21832-21840 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T153 23055-23057 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T154 23304-23311 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T155 24310-24325 Chemical denotes Alexa Fluor 488 http://purl.obolibrary.org/obo/CHEBI_52661
T156 24316-24321 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T157 24423-24429 Chemical denotes nuclei http://purl.obolibrary.org/obo/CHEBI_33252
T158 24455-24459 Chemical denotes DAPI http://purl.obolibrary.org/obo/CHEBI_51231
T159 24680-24682 Chemical denotes SD http://purl.obolibrary.org/obo/CHEBI_74807
T160 24863-24871 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T161 24998-25000 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T162 25001-25003 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T163 25004-25006 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T164 25040-25048 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T165 25261-25269 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T166 25308-25316 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T167 25452-25460 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T168 25489-25496 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T169 25504-25511 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T170 25522-25529 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T171 25566-25574 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T172 25607-25609 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T173 26028-26036 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T174 26305-26313 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T175 26385-26393 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T176 26546-26553 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T177 26616-26624 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T178 26681-26689 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T179 26819-26824 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T180 26825-26829 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T181 26861-26868 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T182 27018-27025 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T183 27034-27055 Chemical denotes S-adenosyl methionine http://purl.obolibrary.org/obo/CHEBI_15414
T184 27036-27044 Chemical denotes adenosyl http://purl.obolibrary.org/obo/CHEBI_33505
T185 27045-27055 Chemical denotes methionine http://purl.obolibrary.org/obo/CHEBI_16811|http://purl.obolibrary.org/obo/CHEBI_64558
T187 27074-27081 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T188 27167-27174 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T189 27385-27392 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T190 27452-27455 Chemical denotes GTP http://purl.obolibrary.org/obo/CHEBI_15996|http://purl.obolibrary.org/obo/CHEBI_37565
T192 27464-27471 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T193 27552-27562 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T194 27630-27644 Chemical denotes macromolecules http://purl.obolibrary.org/obo/CHEBI_33839
T195 27683-27687 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T196 27726-27729 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T197 27768-27771 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T198 27788-27795 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T199 27858-27861 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T200 27883-27891 Chemical denotes Collagen http://purl.obolibrary.org/obo/CHEBI_3815
T201 27897-27899 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T202 27900-27905 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T203 28006-28008 Chemical denotes T2 http://purl.obolibrary.org/obo/CHEBI_29298|http://purl.obolibrary.org/obo/CHEBI_75710
T205 28053-28055 Chemical denotes T2 http://purl.obolibrary.org/obo/CHEBI_29298|http://purl.obolibrary.org/obo/CHEBI_75710
T207 28333-28339 Chemical denotes amyrin http://purl.obolibrary.org/obo/CHEBI_10352
T208 28409-28416 Chemical denotes Calcium http://purl.obolibrary.org/obo/CHEBI_22984
T209 28457-28462 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T210 28614-28617 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T211 28656-28665 Chemical denotes Prolactin http://purl.obolibrary.org/obo/CHEBI_81580
T212 28833-28836 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T213 28952-28960 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T214 28990-29013 Chemical denotes low density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39026
T215 29002-29013 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T216 29203-29206 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T217 29289-29292 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T218 29422-29444 Chemical denotes Nucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_16862
T219 29422-29432 Chemical denotes Nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T220 29433-29444 Chemical denotes diphosphate http://purl.obolibrary.org/obo/CHEBI_18361|http://purl.obolibrary.org/obo/CHEBI_33019
T222 29506-29530 Chemical denotes nucleoside triphosphates http://purl.obolibrary.org/obo/CHEBI_17326
T223 29506-29516 Chemical denotes nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T224 29555-29559 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T226 29717-29724 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T227 29995-29997 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T228 30119-30121 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T229 30361-30368 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T230 30396-30399 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T233 30400-30406 Chemical denotes ribose http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013
T235 30460-30463 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T238 30464-30470 Chemical denotes ribose http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013
T240 30514-30521 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T241 30563-30577 Chemical denotes Protein serine http://purl.obolibrary.org/obo/CHEBI_8572
T242 30563-30570 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T243 30571-30577 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T244 30578-30587 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T245 30692-30699 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T246 30730-30737 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T247 30924-30931 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T248 30991-31004 Chemical denotes Ribosomal RNA http://purl.obolibrary.org/obo/CHEBI_18111
T249 31005-31012 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T250 31083-31090 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T251 31133-31141 Chemical denotes tyrosine http://purl.obolibrary.org/obo/CHEBI_18186
T252 31183-31197 Chemical denotes Protein serine http://purl.obolibrary.org/obo/CHEBI_8572
T253 31183-31190 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T254 31191-31197 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T255 31198-31207 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T256 31229-31232 Chemical denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T259 31233-31239 Chemical denotes ribose http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013
T261 31349-31356 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T262 31420-31427 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T263 31428-31434 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T264 31435-31444 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T265 31505-31513 Chemical denotes Cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T266 31519-31542 Chemical denotes endopeptidase inhibitor http://purl.obolibrary.org/obo/CHEBI_82973
T267 31533-31542 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T268 31574-31595 Chemical denotes divalent metal cation http://purl.obolibrary.org/obo/CHEBI_60240
T269 31583-31595 Chemical denotes metal cation http://purl.obolibrary.org/obo/CHEBI_25213
T270 31589-31595 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T271 31674-31681 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T272 31682-31688 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T273 31689-31698 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T274 31738-31752 Chemical denotes Protein serine http://purl.obolibrary.org/obo/CHEBI_8572
T275 31738-31745 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T276 31746-31752 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T277 31753-31762 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T278 31802-31809 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T279 31862-31872 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T280 31862-31867 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T281 31868-31872 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T282 31889-31904 Chemical denotes complex protein http://purl.obolibrary.org/obo/CHEBI_33837
T283 31897-31904 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T284 32011-32018 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T285 32077-32100 Chemical denotes Endopeptidase inhibitor http://purl.obolibrary.org/obo/CHEBI_82973
T286 32091-32100 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T287 32122-32128 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T288 32129-32138 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T289 32139-32146 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T290 32215-32218 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T291 32248-32255 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T292 32424-32431 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T293 32495-32502 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T294 32619-32637 Chemical denotes small nuclear RNAs http://purl.obolibrary.org/obo/CHEBI_74035
T295 32639-32644 Chemical denotes snRNA http://purl.obolibrary.org/obo/CHEBI_74035
T296 32766-32793 Chemical denotes very long chain fatty acids http://purl.obolibrary.org/obo/CHEBI_27283
T297 32782-32793 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T298 32788-32793 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T299 32794-32801 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T300 32920-32927 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T301 32948-32955 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T302 32989-32996 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T303 33050-33057 Chemical denotes Calcium http://purl.obolibrary.org/obo/CHEBI_22984
T304 33058-33061 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T305 33182-33189 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T306 33283-33290 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T307 33397-33404 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T308 33440-33447 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T309 33482-33489 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T310 33633-33640 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T311 33691-33698 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T312 33752-33759 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T313 33801-33804 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T314 33812-33819 Chemical denotes Trypsin http://purl.obolibrary.org/obo/CHEBI_9765
T315 33872-33878 Chemical denotes Serine http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_17822
T317 33907-33918 Chemical denotes UDP-glucose http://purl.obolibrary.org/obo/CHEBI_18066
T318 33907-33910 Chemical denotes UDP http://purl.obolibrary.org/obo/CHEBI_17659|http://purl.obolibrary.org/obo/CHEBI_58223
T320 33911-33918 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167
T322 33919-33931 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T323 33986-33998 Chemical denotes Glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T324 34028-34056 Chemical denotes Phosphatidylglycerophosphate http://purl.obolibrary.org/obo/CHEBI_17264|http://purl.obolibrary.org/obo/CHEBI_37393
T326 34100-34107 Chemical denotes Calcium http://purl.obolibrary.org/obo/CHEBI_22984
T327 34108-34111 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T328 34178-34181 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T329 34456-34458 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T330 34459-34461 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T331 34462-34464 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T332 34853-34861 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T333 35044-35046 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T334 35196-35204 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T335 35558-35565 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T336 35646-35653 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T337 35890-35892 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T338 35949-35951 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T339 36106-36108 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T340 36109-36111 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T341 36112-36114 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T342 36918-36920 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T343 37041-37049 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T344 37738-37740 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T345 37903-37911 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T346 37965-37967 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T347 37990-37992 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T348 38019-38021 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T349 38035-38037 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T350 38052-38060 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T351 38346-38348 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T352 38493-38495 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T353 38510-38518 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T354 38804-38806 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T355 38821-38829 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T356 38911-38919 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T357 38956-38967 Chemical denotes antioxidant http://purl.obolibrary.org/obo/CHEBI_22586
T358 39150-39158 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T359 39266-39274 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T360 39280-39288 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T361 39353-39355 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T362 39378-39380 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T363 39407-39409 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T364 39551-39559 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T365 39602-39610 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T366 39712-39720 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T367 40207-40215 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T368 40315-40317 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T369 40334-40342 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T370 40395-40403 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T371 40438-40446 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T372 40498-40506 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T373 40528-40535 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T374 40596-40604 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T375 40685-40693 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T376 40750-40758 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T377 40816-40824 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T378 40846-40858 Chemical denotes carbohydrate http://purl.obolibrary.org/obo/CHEBI_16646
T379 40891-40899 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T380 40972-40982 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T381 41009-41014 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T382 41131-41144 Chemical denotes inorganic ion http://purl.obolibrary.org/obo/CHEBI_36914
T383 41141-41144 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T384 41234-41242 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T385 41385-41393 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T386 41508-41516 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T387 41706-41714 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T388 41744-41751 Chemical denotes Pathway http://purl.obolibrary.org/obo/CHEBI_34922
T389 42034-42042 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T390 42396-42398 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T391 42421-42429 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T392 42487-42489 Chemical denotes 5B http://purl.obolibrary.org/obo/CHEBI_27560
T393 42692-42700 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T394 42912-42919 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T395 42957-42964 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T396 43007-43012 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T397 43333-43336 Chemical denotes AGE http://purl.obolibrary.org/obo/CHEBI_84123
T398 43395-43401 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T400 43449-43454 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T401 43504-43521 Chemical denotes glycosaminoglycan http://purl.obolibrary.org/obo/CHEBI_18085
T402 43536-43548 Chemical denotes progesterone http://purl.obolibrary.org/obo/CHEBI_17026
T403 43878-43886 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T404 44004-44012 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T405 44196-44198 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T406 44233-44236 Chemical denotes GIP http://purl.obolibrary.org/obo/CHEBI_80165
T407 44307-44309 Chemical denotes CP http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461
T409 44348-44356 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T410 44444-44452 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T411 44525-44533 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T412 44604-44612 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T413 44966-44973 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T414 44974-44981 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T415 45040-45047 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T416 45139-45146 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T417 45147-45154 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T418 45316-45323 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T419 45495-45503 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T420 45770-45778 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T421 45790-45798 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T422 46043-46051 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T423 46291-46299 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T424 46347-46354 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T425 46515-46522 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T426 46523-46530 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T427 46587-46595 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T428 46778-46785 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T429 46855-46863 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T430 47186-47194 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T431 47368-47377 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T432 47414-47416 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T433 47699-47706 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T434 47790-47792 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T435 47793-47795 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T436 47796-47798 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T437 47900-47902 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T438 47913-47915 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T439 48395-48403 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T440 48442-48450 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T441 48524-48532 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T442 48597-48605 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T443 48791-48798 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T444 49253-49261 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T445 49262-49270 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T446 49340-49358 Chemical denotes triphosphate group http://purl.obolibrary.org/obo/CHEBI_32959|http://purl.obolibrary.org/obo/CHEBI_68550
T448 49340-49352 Chemical denotes triphosphate http://purl.obolibrary.org/obo/CHEBI_18036
T449 49353-49358 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T49184 50105-50113 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T98776 50209-50219 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T60756 50221-50224 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T58240 50236-50244 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T26062 50306-50308 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T23684 50396-50404 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T58411 50474-50476 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T90327 50578-50585 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T89594 50600-50611 Chemical denotes calcium ion http://purl.obolibrary.org/obo/CHEBI_39124
T8948 50600-50607 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T6312 50608-50611 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T60218 50620-50627 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T35294 50670-50672 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T54697 50711-50725 Chemical denotes apolipoprotein http://purl.obolibrary.org/obo/CHEBI_39015
T42534 50734-50741 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T52776 50799-50806 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T67126 50839-50841 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T25753 50918-50926 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T7958 51001-51009 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T63936 51090-51092 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T35836 51288-51296 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T69265 51446-51454 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T94431 51633-51641 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T70471 51798-51806 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T26 52021-52029 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T65075 52650-52658 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T28 52775-52783 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T95720 52884-52892 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T77842 52979-52987 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T31 52994-52996 Chemical denotes MT http://purl.obolibrary.org/obo/CHEBI_73614
T32 53075-53083 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T46428 53149-53156 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T55690 53229-53232 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T35 53245-53252 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T36 53283-53292 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T28170 53451-53463 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T10122 53459-53463 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T59838 53594-53603 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T40 53825-53827 Chemical denotes IV http://purl.obolibrary.org/obo/CHEBI_74327
T41 53837-53842 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T42 54017-54024 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T84303 54654-54657 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T2647 54678-54681 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T3272 54682-54691 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T35749 54705-54708 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T79198 54768-54777 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T25165 54866-54874 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T75260 55002-55010 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T20380 55029-55032 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T14676 55236-55239 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T50278 55530-55532 Chemical denotes PK http://purl.obolibrary.org/obo/CHEBI_74792
T42745 55766-55769 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T54 56164-56171 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38201 56200-56203 Chemical denotes IFN http://purl.obolibrary.org/obo/CHEBI_52999
T41383 56246-56265 Chemical denotes double-stranded RNA http://purl.obolibrary.org/obo/CHEBI_67208
T79790 56919-56924 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T7173 56937-56944 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T17429 59102-59110 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T60 59290-59304 Chemical denotes macromolecules http://purl.obolibrary.org/obo/CHEBI_33839
T4787 59525-59528 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T60517 59714-59716 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T62319 59817-59820 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T20667 60356-60358 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T59893 60558-60567 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T49991 61476-61485 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T37870 61486-61493 Chemical denotes MK-2206 http://purl.obolibrary.org/obo/CHEBI_67271
T94018 61486-61488 Chemical denotes MK http://purl.obolibrary.org/obo/CHEBI_74706
T27802 61825-61831 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T71 61848-61858 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T59320 61960-61970 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T47204 61972-61985 Chemical denotes cycloheximide http://purl.obolibrary.org/obo/CHEBI_27641
T76342 61990-61997 Chemical denotes emetine http://purl.obolibrary.org/obo/CHEBI_4781
T73678 62073-62088 Chemical denotes pharmaceuticals http://purl.obolibrary.org/obo/CHEBI_52217
T90954 62362-62371 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T83300 62477-62482 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T10537 62513-62522 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T18811 62622-62629 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T55089 62742-62744 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T81472 62745-62747 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T38162 62748-62750 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T21097 62797-62805 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T1741 62827-62835 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T85 63685-63687 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T86 63688-63690 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T21623 63691-63693 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T11161 63735-63737 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T87398 63882-63890 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T91659 63964-63966 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T24070 63967-63969 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T62528 64003-64005 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T19691 64013-64021 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T5727 64091-64093 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T91121 64153-64161 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T71159 64188-64190 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T34813 64255-64263 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T8298 64290-64292 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T1072 64351-64359 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T55282 64450-64458 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T87000 64551-64559 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T34522 64844-64846 Chemical denotes Ge http://purl.obolibrary.org/obo/CHEBI_30441
T34404 64852-64855 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T41324 65123-65125 Chemical denotes LC http://purl.obolibrary.org/obo/CHEBI_73582
T76761 65126-65128 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T97320 65129-65131 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 248-256 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T2 2331-2339 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T3 2347-2355 Phenotype denotes vomiting http://purl.obolibrary.org/obo/HP_0002013
T4 2357-2368 Phenotype denotes dehydration http://purl.obolibrary.org/obo/HP_0001944
T5 3531-3539 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T6 5895-5900 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T7 6590-6598 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T8 29144-29160 Phenotype denotes Myeloid leukemia http://purl.obolibrary.org/obo/HP_0012324
T9 30784-30790 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T10 42657-42663 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T11 43416-43422 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T12 43480-43502 Phenotype denotes small cell lung cancer http://purl.obolibrary.org/obo/HP_0030357
T13 53033-53039 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T14 54258-54263 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T15 57121-57127 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T16 59945-59951 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T17 59953-59976 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T18 60164-60180 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 898-906 http://purl.obolibrary.org/obo/GO_0051322 denotes anaphase
T2 1331-1349 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T3 1331-1340 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T4 1392-1411 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T5 1399-1411 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T6 1440-1444 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T7 1450-1459 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T8 1450-1459 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T9 1465-1475 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T10 1476-1494 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T11 1476-1485 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T12 1645-1657 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T13 2925-2933 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T14 2925-2933 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T15 2925-2933 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T16 2925-2933 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T17 4574-4589 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T18 4612-4631 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T19 4619-4631 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T20 4825-4841 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T21 4892-4904 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T22 5735-5758 http://purl.obolibrary.org/obo/GO_0019048 denotes virus-host interactions
T23 6086-6098 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T24 7613-7641 http://purl.obolibrary.org/obo/GO_0004601 denotes Horseradish peroxidase (HRP)
T25 8491-8497 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T26 9906-9915 http://purl.obolibrary.org/obo/GO_0007586 denotes Digestion
T27 10357-10362 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T28 11015-11024 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T29 11178-11183 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T30 11868-11877 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T31 14957-14966 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion
T32 17453-17468 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T33 17844-17853 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T34 23416-23422 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T35 24500-24506 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T36 24578-24593 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T37 24827-24842 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T38 25539-25549 http://purl.obolibrary.org/obo/GO_0004175 denotes proteinase
T39 26910-26935 http://purl.obolibrary.org/obo/GO_0051607 denotes Defense response to virus
T40 26918-26935 http://purl.obolibrary.org/obo/GO_0009615 denotes response to virus
T41 27122-27147 http://purl.obolibrary.org/obo/GO_0051607 denotes Defense response to virus
T42 27130-27147 http://purl.obolibrary.org/obo/GO_0009615 denotes response to virus
T43 27246-27285 http://purl.obolibrary.org/obo/GO_0050688 denotes Regulation of defense response to virus
T44 27260-27285 http://purl.obolibrary.org/obo/GO_0051607 denotes defense response to virus
T45 27260-27276 http://purl.obolibrary.org/obo/GO_0006952 denotes defense response
T46 27524-27562 http://purl.obolibrary.org/obo/GO_0071357 denotes cellular response to type I interferon
T47 27533-27562 http://purl.obolibrary.org/obo/GO_0034340 denotes response to type I interferon
T48 27653-27673 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T49 27653-27666 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T50 27726-27767 http://purl.obolibrary.org/obo/GO_0003700 denotes DNA-binding transcription factor activity
T51 27738-27758 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T52 27738-27751 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T53 27768-27780 http://purl.obolibrary.org/obo/GO_0044349 denotes DNA excision
T54 27862-27882 http://purl.obolibrary.org/obo/GO_0140303 denotes translocase activity
T55 28104-28115 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T56 28158-28169 http://purl.obolibrary.org/obo/GO_0016791 denotes Phosphatase
T57 28232-28257 http://purl.obolibrary.org/obo/GO_0030100 denotes Regulation of endocytosis
T58 28246-28257 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T59 28537-28563 http://purl.obolibrary.org/obo/GO_0004896 denotes cytokine receptor activity
T60 28546-28563 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T61 28614-28655 http://purl.obolibrary.org/obo/GO_0003700 denotes DNA-binding transcription factor activity
T62 28626-28646 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T63 28626-28639 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T64 28725-28750 http://purl.obolibrary.org/obo/GO_0005096 denotes GTPase activator activity
T65 28863-28887 http://purl.obolibrary.org/obo/GO_0042073 denotes Intraflagellar transport
T66 28863-28887 http://purl.obolibrary.org/obo/GO_0035735 denotes Intraflagellar transport
T67 28878-28887 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T68 29065-29079 http://purl.obolibrary.org/obo/GO_0005319 denotes Apolipoprotein
T69 29229-29249 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factor
T70 29229-29242 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T71 29390-29421 http://purl.obolibrary.org/obo/GO_0042981 denotes Regulation of apoptotic process
T72 29404-29421 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptotic process
T73 29493-29502 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T74 29717-29740 http://purl.obolibrary.org/obo/GO_0004672 denotes Protein kinase activity
T75 29725-29740 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T76 29872-29890 http://purl.obolibrary.org/obo/GO_0031497 denotes Chromatin assembly
T77 30026-30037 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T78 30179-30203 http://purl.obolibrary.org/obo/GO_0042073 denotes Intraflagellar transport
T79 30179-30203 http://purl.obolibrary.org/obo/GO_0035735 denotes Intraflagellar transport
T80 30194-30203 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T81 30241-30293 http://purl.obolibrary.org/obo/GO_0050680 denotes Negative regulation of epithelial cell proliferation
T82 30250-30293 http://purl.obolibrary.org/obo/GO_0050678 denotes regulation of epithelial cell proliferation
T83 30250-30260 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T84 30264-30293 http://purl.obolibrary.org/obo/GO_0050673 denotes epithelial cell proliferation
T85 30275-30293 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T86 30563-30603 http://purl.obolibrary.org/obo/GO_0004674 denotes Protein serine/threonine kinase activity
T87 30588-30603 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T88 30604-30612 http://purl.obolibrary.org/obo/GO_0051322 denotes Anaphase
T89 30682-30715 http://purl.obolibrary.org/obo/GO_0061630 denotes Ubiquitin protein ligase activity
T90 30682-30715 http://purl.obolibrary.org/obo/GO_0004842 denotes Ubiquitin protein ligase activity
T91 31077-31126 http://purl.obolibrary.org/obo/GO_0000179 denotes rRNA (adenine-N6,N6)-dimethyltransferase activity
T92 31183-31223 http://purl.obolibrary.org/obo/GO_0004674 denotes Protein serine/threonine kinase activity
T93 31208-31223 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T94 31312-31325 http://purl.obolibrary.org/obo/GO_0000209 denotes polyubiquitin
T95 31403-31409 http://purl.obolibrary.org/obo/GO_0016538 denotes Cyclin
T96 31420-31460 http://purl.obolibrary.org/obo/GO_0004674 denotes protein serine/threonine kinase activity
T97 31445-31460 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T98 31461-31469 http://purl.obolibrary.org/obo/GO_0004869 denotes Cystatin
T99 31505-31551 http://purl.obolibrary.org/obo/GO_0004869 denotes Cysteine-type endopeptidase inhibitor activity
T100 31519-31551 http://purl.obolibrary.org/obo/GO_0004866 denotes endopeptidase inhibitor activity
T101 31552-31558 http://purl.obolibrary.org/obo/GO_0016538 denotes Cyclin
T102 31589-31605 http://purl.obolibrary.org/obo/GO_0006812 denotes cation transport
T103 31596-31605 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T104 31738-31778 http://purl.obolibrary.org/obo/GO_0004674 denotes Protein serine/threonine kinase activity
T105 31763-31778 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity
T106 31852-31882 http://purl.obolibrary.org/obo/GO_0051957 denotes activity; amino acid transport
T107 31862-31882 http://purl.obolibrary.org/obo/GO_0006865 denotes amino acid transport
T108 31873-31882 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T109 31943-31966 http://purl.obolibrary.org/obo/GO_0010506 denotes Regulation of autophagy
T110 31957-31966 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T111 31957-31966 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T112 31968-32004 http://purl.obolibrary.org/obo/GO_0032008 denotes positive regulation of TOR signaling
T113 31977-32004 http://purl.obolibrary.org/obo/GO_0032006 denotes regulation of TOR signaling
T114 31977-31987 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T115 31991-32004 http://purl.obolibrary.org/obo/GO_0031929 denotes TOR signaling
T116 31995-32004 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T117 32077-32109 http://purl.obolibrary.org/obo/GO_0004866 denotes Endopeptidase inhibitor activity
T118 32194-32214 http://purl.obolibrary.org/obo/GO_0051347 denotes Transferase activity
T119 32381-32401 http://purl.obolibrary.org/obo/GO_0051347 denotes Transferase activity
T120 32656-32669 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T121 32720-32751 http://purl.obolibrary.org/obo/GO_0030036 denotes Actin cytoskeleton organization
T122 32726-32751 http://purl.obolibrary.org/obo/GO_0007010 denotes cytoskeleton organization
T123 32989-33006 http://purl.obolibrary.org/obo/GO_0015031 denotes Protein transport
T124 32997-33006 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T125 33123-33152 http://purl.obolibrary.org/obo/GO_0004784 denotes Superoxide dismutase activity
T126 33162-33181 http://purl.obolibrary.org/obo/GO_0042254 denotes ribosome biogenesis
T127 33263-33282 http://purl.obolibrary.org/obo/GO_0042254 denotes ribosome biogenesis
T128 33351-33361 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T129 33365-33422 http://purl.obolibrary.org/obo/GO_0043161 denotes proteasomal ubiquitin-dependent protein catabolic process
T130 33377-33422 http://purl.obolibrary.org/obo/GO_0006511 denotes ubiquitin-dependent protein catabolic process
T131 33397-33422 http://purl.obolibrary.org/obo/GO_0030163 denotes protein catabolic process
T132 33405-33422 http://purl.obolibrary.org/obo/GO_0009056 denotes catabolic process
T133 33586-33625 http://purl.obolibrary.org/obo/GO_0046921 denotes Alpha-(1→6)-fucosyltransferase activity
T134 33598-33625 http://purl.obolibrary.org/obo/GO_0008417 denotes fucosyltransferase activity
T135 33801-33811 http://purl.obolibrary.org/obo/GO_0006281 denotes DNA repair
T136 33872-33906 http://purl.obolibrary.org/obo/GO_0004252 denotes Serine-type endopeptidase activity
T137 33884-33906 http://purl.obolibrary.org/obo/GO_0004175 denotes endopeptidase activity
T138 34506-34519 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T139 38129-38150 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T140 38136-38150 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T141 38152-38172 http://purl.obolibrary.org/obo/GO_0022414 denotes reproductive process
T142 38174-38193 http://purl.obolibrary.org/obo/GO_0022610 denotes biological adhesion
T143 38195-38216 http://purl.obolibrary.org/obo/GO_0051704 denotes multiorganism process
T144 38218-38232 http://purl.obolibrary.org/obo/GO_0098754 denotes detoxification
T145 38234-38266 http://purl.obolibrary.org/obo/GO_0032501 denotes multicellular organismal process
T146 38268-38289 http://purl.obolibrary.org/obo/GO_0032502 denotes developmental process
T147 38291-38303 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T148 38385-38406 http://purl.obolibrary.org/obo/GO_0051704 denotes multiorganism process
T149 38408-38422 http://purl.obolibrary.org/obo/GO_0098754 denotes detoxification
T150 38428-38440 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T151 38920-38950 http://purl.obolibrary.org/obo/GO_0032411 denotes activity, transporter activity
T152 38920-38941 http://purl.obolibrary.org/obo/GO_0015291 denotes activity, transporter
T153 38956-38976 http://purl.obolibrary.org/obo/GO_0016209 denotes antioxidant activity
T154 40421-40434 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T155 40464-40483 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T156 40471-40483 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T157 40546-40576 http://purl.obolibrary.org/obo/GO_0043687 denotes posttranslational modification
T158 40620-40639 http://purl.obolibrary.org/obo/GO_0016192 denotes vesicular transport
T159 40630-40639 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T160 40672-40681 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T161 40715-40729 http://purl.obolibrary.org/obo/GO_0006396 denotes RNA processing
T162 40846-40868 http://purl.obolibrary.org/obo/GO_0008643 denotes carbohydrate transport
T163 40859-40868 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T164 40873-40883 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T165 40972-40992 http://purl.obolibrary.org/obo/GO_0006862 denotes nucleotide transport
T166 40983-40992 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T167 40997-41007 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T168 41009-41024 http://purl.obolibrary.org/obo/GO_0006869 denotes lipid transport
T169 41015-41024 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T170 41029-41039 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T171 41041-41052 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T172 41141-41154 http://purl.obolibrary.org/obo/GO_0006811 denotes ion transport
T173 41145-41154 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T174 41159-41169 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T175 41799-41817 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T176 41799-41808 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T177 42086-42105 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T178 42093-42105 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T179 42255-42265 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T180 42357-42375 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T181 42521-42539 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T182 42521-42530 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T183 42585-42602 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T184 42585-42594 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T185 42604-42608 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T186 42609-42622 http://purl.obolibrary.org/obo/GO_0043491 denotes AKT signaling
T187 42613-42622 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T188 42632-42643 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T189 42790-42808 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T190 42790-42799 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T191 42840-42844 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T192 42851-42869 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T193 42851-42860 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T194 43024-43036 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T195 43123-43141 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T196 43123-43132 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T197 43264-43281 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T198 43264-43273 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T199 43342-43359 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T200 43342-43351 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T201 43402-43412 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T202 43466-43478 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T203 43504-43534 http://purl.obolibrary.org/obo/GO_0006024 denotes glycosaminoglycan biosynthesis
T204 43522-43534 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T205 43558-43575 http://purl.obolibrary.org/obo/GO_0001556 denotes oocyte maturation
T206 43589-43606 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T207 43589-43598 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T208 43626-43644 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T209 43626-43635 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T210 43763-43773 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T211 44164-44174 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T212 44287-44305 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T213 44307-44309 http://purl.obolibrary.org/obo/GO_0009987 denotes CP
T214 45582-45597 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T215 45711-45721 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T216 46143-46147 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T217 46180-46190 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T218 46491-46503 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T219 47262-47277 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T220 47528-47544 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T221 48773-48786 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T222 48884-48892 http://purl.obolibrary.org/obo/GO_0051322 denotes anaphase
T223 49081-49092 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T224 49100-49121 http://purl.obolibrary.org/obo/GO_0051726 denotes cell cycle regulators
T225 49100-49110 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T226 49239-49252 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T227 49450-49473 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune responses
T228 50338-50359 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T229 50345-50359 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T230 50374-50395 http://purl.obolibrary.org/obo/GO_0051726 denotes cell cycle-regulating
T231 50374-50384 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T232 50510-50530 http://purl.obolibrary.org/obo/GO_0022414 denotes reproductive process
T233 50711-50725 http://purl.obolibrary.org/obo/GO_0005319 denotes apolipoprotein
T234 50756-50774 http://purl.obolibrary.org/obo/GO_1901987 denotes cell cycle control
T235 50756-50766 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T236 51010-51040 http://purl.obolibrary.org/obo/GO_0032411 denotes activity, transporter activity
T237 51010-51031 http://purl.obolibrary.org/obo/GO_0015291 denotes activity, transporter
T238 51416-51437 http://purl.obolibrary.org/obo/GO_0002376 denotes immune system process
T239 51423-51437 http://purl.obolibrary.org/obo/GO_0003008 denotes system process
T240 51558-51577 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T241 51565-51577 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T242 51900-51913 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T243 52261-52279 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T244 52261-52270 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T245 52515-52533 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T246 52515-52524 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T247 52721-52740 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T248 52728-52740 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T249 52797-52801 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T250 53013-53021 http://purl.obolibrary.org/obo/GO_0004869 denotes cystatin
T251 53084-53088 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T252 53186-53204 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T253 53186-53195 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T254 53293-53308 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T255 53347-53365 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T256 53347-53356 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T257 53546-53557 http://purl.obolibrary.org/obo/GO_0032259 denotes methylation
T258 53657-53679 http://purl.obolibrary.org/obo/GO_0006413 denotes translation initiation
T259 53657-53668 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T260 53765-53783 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T261 53765-53774 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T262 53904-53922 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T263 53904-53913 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T264 53960-53979 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T265 53967-53979 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T266 54124-54138 http://purl.obolibrary.org/obo/GO_0035148 denotes tube formation
T267 54129-54138 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T268 54264-54276 http://purl.obolibrary.org/obo/GO_0001525 denotes angiogenesis
T269 54301-54319 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T270 54301-54310 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T271 54350-54354 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T272 54370-54379 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T273 54370-54379 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T274 54380-54398 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T275 54380-54389 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T276 54607-54625 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T277 54607-54616 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T278 54778-54791 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T279 55088-55104 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T280 55240-55258 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T281 55240-55249 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T282 55434-55451 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T283 55434-55443 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T284 55682-55697 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T285 55818-55833 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T286 55922-55947 http://purl.obolibrary.org/obo/GO_0004521 denotes endoribonuclease activity
T287 56079-56092 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T288 56113-56130 http://purl.obolibrary.org/obo/GO_0008233 denotes protease activity
T289 56319-56336 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T290 56319-56328 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T291 56358-56376 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T292 56358-56367 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T293 56378-56382 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T294 56479-56499 http://purl.obolibrary.org/obo/GO_0010506 denotes regulating autophagy
T295 56490-56499 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T296 56490-56499 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T297 56507-56511 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T298 56512-56525 http://purl.obolibrary.org/obo/GO_0043491 denotes AKT signaling
T299 56516-56525 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T300 56722-56740 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T301 56761-56770 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T302 56761-56770 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T303 56772-56782 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T304 56829-56846 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T305 56829-56838 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T306 56937-56954 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T307 56945-56954 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T308 56956-56979 http://purl.obolibrary.org/obo/GO_0010506 denotes regulation of autophagy
T309 56956-56966 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T310 56970-56979 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T311 56970-56979 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T312 57153-57157 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T313 57158-57171 http://purl.obolibrary.org/obo/GO_0043491 denotes AKT signaling
T314 57162-57171 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T315 57208-57237 http://purl.obolibrary.org/obo/GO_0010508 denotes positively regulate autophagy
T316 57219-57237 http://purl.obolibrary.org/obo/GO_0010506 denotes regulate autophagy
T317 57228-57237 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T318 57228-57237 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T319 57311-57320 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T320 57311-57320 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T321 57347-57351 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T322 57361-57378 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T323 57361-57370 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T324 57430-57461 http://purl.obolibrary.org/obo/GO_0010507 denotes negatively regulating autophagy
T325 57441-57461 http://purl.obolibrary.org/obo/GO_0010506 denotes regulating autophagy
T326 57452-57461 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T327 57452-57461 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T328 57512-57516 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T329 57530-57548 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T330 57530-57539 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T331 57706-57710 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T332 57720-57737 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T333 57720-57729 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T334 57809-57818 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T335 57809-57818 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T336 57939-57948 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T337 57939-57948 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T338 58072-58081 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T339 58072-58081 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T340 58135-58144 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T341 58135-58144 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T342 58148-58165 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T343 58148-58165 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T344 58234-58243 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T345 58234-58243 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T346 58273-58277 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T347 58287-58304 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T348 58287-58296 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T349 58398-58418 http://purl.obolibrary.org/obo/GO_0010506 denotes regulating autophagy
T350 58409-58418 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T351 58409-58418 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T352 58606-58610 http://purl.obolibrary.org/obo/GO_0004740 denotes PDK1
T353 58620-58630 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T354 58631-58649 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T355 58631-58640 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T356 58788-58806 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T357 58788-58797 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T358 58870-58888 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T359 58870-58879 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T360 58947-58957 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T361 58958-58975 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T362 58958-58967 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T363 59135-59145 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T364 59146-59163 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T365 59146-59155 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T366 59502-59520 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T367 59525-59535 http://purl.obolibrary.org/obo/GO_0006281 denotes DNA repair
T368 59556-59562 http://purl.obolibrary.org/obo/GO_0016538 denotes cyclin
T369 59585-59598 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T370 59648-59663 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T371 59817-59827 http://purl.obolibrary.org/obo/GO_0006281 denotes DNA repair
T372 59832-59841 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T373 59832-59841 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T374 59981-59998 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T375 59981-59998 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T376 60378-60397 http://purl.obolibrary.org/obo/GO_0019083 denotes viral transcription
T377 60384-60397 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T378 60444-60457 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T379 60609-60627 http://purl.obolibrary.org/obo/GO_0009299 denotes mRNA transcription
T380 60614-60627 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T381 61344-61362 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T382 61344-61353 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T383 61514-61531 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T384 61514-61523 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T385 61788-61799 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T386 61815-61823 http://purl.obolibrary.org/obo/GO_0045292 denotes splicing
T387 61832-61842 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T388 61848-61869 http://purl.obolibrary.org/obo/GO_0009117 denotes nucleotide metabolism
T389 61859-61869 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T390 61891-61906 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T391 61948-61959 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T392 62327-62345 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T393 62327-62336 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T394 62389-62414 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibit viral replication
T395 62397-62414 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T396 62397-62414 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T397 63023-63041 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T398 63023-63032 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T399 63084-63103 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T400 63091-63103 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T401 63136-63140 http://purl.obolibrary.org/obo/GO_0016303 denotes PI3K
T402 63146-63155 http://purl.obolibrary.org/obo/GO_0016236 denotes autophagy
T403 63146-63155 http://purl.obolibrary.org/obo/GO_0006914 denotes autophagy
T404 63161-63171 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T405 63172-63190 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathways
T406 63172-63181 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-138 Sentence denotes Quantitative Proteomic Analysis of Porcine Intestinal Epithelial Cells Infected with Porcine Deltacoronavirus Using iTRAQ-Coupled LC-MS/MS
T2 140-148 Sentence denotes Abstract
T3 149-257 Sentence denotes Porcine deltacoronavirus (PDCoV) is an emergent enteropathogenic coronavirus associated with swine diarrhea.
T4 258-363 Sentence denotes Porcine small intestinal epithelial cells (IPEC) are the primary target cells of PDCoV infection in vivo.
T5 364-620 Sentence denotes Here, isobaric tags for relative and absolute quantification (iTRAQ) labeling coupled to liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to quantitatively identify differentially expressed proteins (DEPs) in PDCoV-infected IPEC-J2 cells.
T6 621-735 Sentence denotes A total of 78 DEPs, including 23 upregulated and 55 downregulated proteins, were identified at 24 h postinfection.
T7 736-805 Sentence denotes The data are available via ProteomeXchange with identifier PXD019975.
T8 806-1161 Sentence denotes To ensure reliability of the proteomics data, two randomly selected DEPs, the downregulated anaphase-promoting complex subunit 7 (ANAPC7) and upregulated interferon-induced protein with tetratricopeptide repeats 1 (IFIT1), were verified by real-time PCR and Western blot, and the results of which indicate that the proteomics data were reliable and valid.
T9 1162-1495 Sentence denotes Bioinformatics analyses, including GO, COG, KEGG, and STRING, further demonstrated that a majority of the DEPs are involved in numerous crucial biological processes and signaling pathways, such as immune system, digestive system, signal transduction, RIG-I-like receptor, mTOR, PI3K-AKT, autophagy, and cell cycle signaling pathways.
T10 1496-1658 Sentence denotes Altogether, this is the first study on proteomes of PDCoV-infected host cells, which shall provide valuable clues for further investigation of PDCoV pathogenesis.
T11 1660-1675 Sentence denotes 1 Introduction
T12 1676-2531 Sentence denotes Porcine deltacoronavirus (PDCoV) is enveloped and has a single-stranded, positive-sense RNA genome, which is classified in the genus Deltacoronavirus within the Coronaviridae family.1 Although PDCoV was initially identified in rectal swabs of pigs during a molecular epidemiological investigation conducted in Hong Kong, China in 2012,2 diarrheal diseases in pigs associated with PDCoV infection were first recorded in the U.S. in 2014.3 Since then, the virus has been detected in many other countries, including Canada, mainland China, South Korea, Thailand, Laos, Vietnam, Japan, Mexico, and so on.4,5 Clinically, PDCoV-infected pigs often present with diarrhea and/or vomiting, dehydration, and death of neonatal piglets.6 The outbreak of PDCoV infection in numerous countries has resulted in considerable economic losses to the global swine industry.7
T13 2532-3304 Sentence denotes PDCoV has an obvious enteropathogenic characteristic in pigs.1,6 The small intestine of pigs, in particular the jejunum and ileum, are the primary target organs of PDCoV, and porcine small intestinal epithelial cells (IPEC) are the main sites of PDCoV replication in vivo.1,8,9 Histopathologic analyses showed that PDCoV infection not only causes villus atrophy and fall-off but also leads to necrosis of small intestinal enterocytes in infected pigs.1,6 Currently, an immortalized, nontumorigenic IPEC-J2 cell line, originally established using the jejunum of a newborn unsuckled piglet,10 has been shown to exhibit high similarities to porcine intestinal primary epithelial cells,11 and thus can better simulate the porcine physiological state than any other cell lines.
T14 3305-3719 Sentence denotes At present, IPEC-J2 cells have been successfully utilized as an ideal in vitro model system for investigating the interactions between epithelial cells and porcine enteric viruses, such as porcine rotavirus,12 porcine endemic diarrhea virus (PEDV),13 and transmissible gastroenteritis virus (TGEV).14 Recently, Jung and colleagues demonstrated that IPEC-J2 cells are quite susceptible to PDCoV infection in vitro.8
T15 3720-3996 Sentence denotes As a newly emerged swine enteropathogenic coronavirus, the pathogenic mechanisms of PDCoV are still poorly documented and warrant further exploration.1 It is well-known that when a virus invades a host cell, complex interactions between the host cell and the virus will occur.
T16 3997-4731 Sentence denotes On the one hand, the invading virus subverts some of the cellular biological functions in favor of the replication of the virus itself; on the other, the cells adopt various defense strategies to fight against the invading virus.15 The whole process of virus–cell interactions is usually accompanied by changes of genomics, transcriptomics, and proteomics.16 Recently, a systematic transcriptome analysis of PDCoV-infected PK-15 cells was conducted using high-throughput RNA sequencing, and 3762 differentially expressed genes were identified, most of which participate in the innate immunity and the corresponding signal transduction pathways.17 As of yet, however, no proteomic data are currently available for PDCoV-infected cells.
T17 4732-5648 Sentence denotes Proteomics is an effective tool for the comprehensive analysis of host cellular responses to viral infections, which is conducive to elucidating the underlying pathogenesis of the virus.18 The currently available proteomics techniques include two-dimensional gel electrophoresis,15 two-dimensional difference gel electrophoresis,19 stable isotope labeling by amino acids in cell culture,20,21 isobaric tags for relative and absolute quantitation (iTRAQ),22 and label-free proteomic techniques.23 Among all these mentioned techniques, iTRAQ coupled with liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis has shown several comparative advantages over its counterparts, for instance, high sensitivity, high throughput, high separating capacity, and high accuracy, and thus emerged as a robust quantitative proteomics technique for the comprehensive analysis of differentially expressed proteins (DEPs).
T18 5649-6099 Sentence denotes To date, this technique has been successfully applied to numerous studies involved in virus-host interactions, examples of which include TGEV,22 PEDV,24 foot-and-mouth disease virus (FMDV),25 porcine circovirus type 2 (PCV2), and classical swine fever virus (CSFV).26 These studies have given a good overview of the dynamic interactions between the virus and its host, and provide important clues for a better understanding of the viral pathogenesis.
T19 6100-6165 Sentence denotes For PDCoV, there has been no proteomic study on the virus so far.
T20 6166-6302 Sentence denotes In the present study, we coupled iTRAQ with LC-MS/MS to quantitatively analyze the DEPs of IPEC-J2 cells in response to PDCoV infection.
T21 6303-6391 Sentence denotes The identified DEPs were subsequently analyzed by comprehensive bioinformatics analyses.
T22 6393-6417 Sentence denotes 2 Materials and Methods
T23 6419-6452 Sentence denotes 2.1 Virus, Cells, and Antibodies
T24 6453-6501 Sentence denotes The PDCoV CHN-HN-1601 strain (GenBank access no.
T25 6502-6642 Sentence denotes MG832584) used in this study was isolated from the intestinal contents of a piglet with diarrhea using porcine kidney LLC-PK1 cells in 2017.
T26 6643-6772 Sentence denotes The eighth passage of PDCoV with a titer of 108.45 50% tissue culture infectious dose (TCID50)/mL was used for virus inoculation.
T27 6773-6903 Sentence denotes IPEC-J2 cells were generously provided by Prof. Yongchang Cao (School of Life Sciences, Sun Yat-Sen University, Guangzhou, China).
T28 6904-7262 Sentence denotes The cells were cultivated in Dulbecco’s Modified Eagle Medium/Ham’s F-12 (DMEM/F12) (Gibco, Carlsbad, CA, USA) containing 10% fetal bovine serum (FBS; Gibco, Carlsbad, CA, USA), 5 μg/mL insulin, 5 μg/mL transferrin, 5 ng/mL selenium (Sigma-Aldrich, St. Louis, MO, USA), 100 U/mL penicillin and 0.1 mg/mL streptomycin (Solarbio Life Sciences, Beijing, China).
T29 7263-7367 Sentence denotes Cells were cultured at 37 °C in a humidified CO2 incubator (Thermo Fisher Scientific, Waltham, MA, USA).
T30 7368-7481 Sentence denotes The monoclonal antibody (mAb), 1A3, raised against the PDCoV nucleocapsid protein was prepared in our laboratory.
T31 7482-7612 Sentence denotes Mouse anti-β-actin mAb, mouse anti-IFIT1 and rabbit anti-ANAPC7 polyclonal antibodies were bought from Abcam (Cambridge, MA, USA).
T32 7613-7731 Sentence denotes Horseradish peroxidase (HRP)-conjugated goat antimouse/rabbit immunoglobulin G (IgG) were obtained from Sigma-Aldrich.
T33 7732-7822 Sentence denotes Alexa Fluor 488-conjugated goat antimouse IgG was the product of Thermo Fisher Scientific.
T34 7824-7846 Sentence denotes 2.2 Virus Inoculation
T35 7847-8094 Sentence denotes IPEC-J2 cells approaching ∼80% confluence were washed twice with sterile phosphate buffered saline (PBS; 0.01 M, pH 7.4), and then mock infected or infected with PDCoV CHN-HN-1601 strain at a multiplicity of infection (MOI) of 0.1 TCID50 per cell.
T36 8095-8263 Sentence denotes After adsorption for 1.5 h at 37 °C, the cells were rinsed once with sterile PBS and serum-free DMEM/F12 medium containing 5 μg/mL of trypsin (Sigma-Aldrich) was added.
T37 8264-8377 Sentence denotes The cells were further cultured at 37 °C for the specified time points until different assays had been performed.
T38 8378-8571 Sentence denotes Viral propagation in IPEC-J2 cells was evaluated by observing cytopathic effect (CPE), determination of one-step growth curve and immunofluorescence assay (IFA) using the mAb 1A3 against PDCoV.
T39 8573-8590 Sentence denotes 2.3 TCID50 Assay
T40 8591-8725 Sentence denotes The kinetics of PDCoV multiplication in IPEC-J2 cells was determined by measuring the TCID50 using a microtitration infectivity assay.
T41 8726-8867 Sentence denotes Briefly, 100 μL/well of 10-fold serial dilutions of PDCoV were inoculated onto IPEC-J2 cells grown in 96-well microplates (Corning, NY, USA).
T42 8868-9015 Sentence denotes After adsorption at 37 °C for 1.5 h, the inocula were removed, and serum-free DMEM/F12 medium containing 5 μg/mL of trypsin was added to the wells.
T43 9016-9197 Sentence denotes After an additional 48-h cultivation, virus titers were measured by observing the presence of visible CPEs in the corresponding wells, and calculated using the Reed–Muench method.27
T44 9199-9207 Sentence denotes 2.4 IFA
T45 9208-9361 Sentence denotes When IPEC-J2 cells grown in 96-well microplates reached ∼80% confluence, they were mock infected or infected with PDCoV at an MOI of 0.1 TCID50 per cell.
T46 9362-9490 Sentence denotes After a 48-h cultivation at 37 °C with 5% CO2, the cells were fixed with prechilled 100% ethanol for 15 min at room temperature.
T47 9491-9589 Sentence denotes After washing with PBS, the cells were probed with the mAb 1A3 (1:5000 dilution) at 37 °C for 1 h.
T48 9590-9767 Sentence denotes Following another washing step, 1000-fold-diluted Alexa Fluor 488-conjugated goat antimouse IgG (Thermo Fisher Scientific) was added to the cells and incubated at 37 °C for 1 h.
T49 9768-9879 Sentence denotes After washing thrice with PBS, cells were observed with an Eclipse Ci-S microscope (Nikon Corp., Tokyo, Japan).
T50 9881-9935 Sentence denotes 2.5 Protein Extraction, Digestion, and iTRAQ Labeling
T51 9936-10140 Sentence denotes At 24 h postinfection (hpi), both PDCoV- and mock-infected IPEC-J2 cells grown in T25 flasks (∼5 × 106 cells/flask) were rinsed twice with prechilled PBS, and then harvested with disposable cell scrapers.
T52 10141-10251 Sentence denotes Three flasks of each group (PDCoV or mock) were harvested and used as three independent biological replicates.
T53 10252-10461 Sentence denotes After centrifugation at 300g for 10 min, the cell pellets from each flask were lysed with 800 μL of RIPA lysis buffer (Beyotime, Shanghai, China) containing 1% SDS, 8 M urea and protease inhibitors (Beyotime).
T54 10462-10567 Sentence denotes The cell lysates were further sonicated on ice for 5 min with 10 s bursts and 10 s pauses between cycles.
T55 10568-10691 Sentence denotes After centrifugation for 20 min at 12 000g and 4 °C, the supernatant was collected and used as the total cellular proteins.
T56 10692-10820 Sentence denotes The concentration of protein samples was determined using a Pierce BCA protein assay kit (Thermo Scientific, Rockford, IL, USA).
T57 10821-11002 Sentence denotes The total cellular proteins from each biological replicate were equally divided into three aliquots, which were used as three independent technical replicates for the LC-MS/MS runs.
T58 11003-11191 Sentence denotes For tryptic digestion and iTRAQ labeling, an aliquot of each protein sample containing ∼100 μg of total cellular proteins was adjusted to a 100-μL final volume using the RIPA lysis buffer.
T59 11192-11341 Sentence denotes A final concentration of 10 mM of tris (2-carboxyethyl) phosphine (TCEP) was added to each protein sample, which was then incubated at 37 °C for 1 h.
T60 11342-11502 Sentence denotes Afterward, iodoacetamide was added at a final concentration of 40 mM, and the protein solution was incubated for 40 min at room temperature shielded from light.
T61 11503-11623 Sentence denotes Subsequently, prechilled acetone was added to the protein solution in a ratio of 6:1 and precipitated at −20 °C for 4 h.
T62 11624-11761 Sentence denotes After centrifugation (10 000g, 4 °C) for 20 min, the precipitate was dissolved with 100 μL of 100 mM triethylammonium bicarbonate (TEAB).
T63 11762-11849 Sentence denotes The processed protein samples were digested with 2 μg/μL of trypsin overnight at 37 °C.
T64 11850-11980 Sentence denotes Following tryptic digestion, the generated peptides were dried by vacuum centrifugation, and redissolved with 20 μL of 0.5 M TEAB.
T65 11981-12123 Sentence denotes The prepared peptides were then labeled with an iTRAQ reagents-8 plex kit (AB Sciex, Foster City, CA, USA) as per the manufacturer’s protocol.
T66 12124-12400 Sentence denotes Briefly, the three independent biological replicates of mock-infected cellular samples were each labeled with iTRAQ-113, iTRAQ-114, and iTRAQ-115; the three independent biological replicates of PDCoV-infected samples were each labeled with iTRAQ-116, iTRAQ-119, and iTRAQ-121.
T67 12401-12676 Sentence denotes All the labeled samples of each group were mixed with an equal amount, and then fractionated using an ACQUITY ultra performance liquid chromatography (UPLC) system (Waters Corp., Milford, MA, USA) combined with an ACQUITY UPLC BEH C18 column (300 Å, 1.7 μm, 2.1 mm × 150 mm).
T68 12677-12739 Sentence denotes Finally, a total of 10 fractions of each group were collected.
T69 12740-12865 Sentence denotes After merging two fractions of each group into one, the pooled 10 fractions were dried by using a rotary vacuum concentrator.
T70 12867-12889 Sentence denotes 2.6 LC-MS/MS Analysis
T71 12890-13097 Sentence denotes LC-MS/MS analyses of the labeled peptides were carried out using a Q-Exactive mass spectrometer (Thermo Fisher Scientific, San Jose, CA, USA) combined with an EASY-nLC 1200 system (Thermo Fisher Scientific).
T72 13098-13458 Sentence denotes After loading 2 μg of the labeled peptides onto a C18 reversed phase HPLC column (Thermo Fisher Scientific), peptides were chromatographed for 120 min at a flow rate of 300 nL/min over gradients from 2–80% (mobile phase A comprising 0.1% (v/v) formic acid and 2% (v/v) acetonitrile; mobile phase B comprising 0.1% (v/v) formic acid and 80% (v/v) acetonitrile).
T73 13459-13600 Sentence denotes The following ion source parameters, including spray voltage 1.8 kV, capillary temperature 275 °C and declustering potential 100 V, were set.
T74 13601-13724 Sentence denotes The mass spectrometer was run using a data-dependent Top-20 acquisition mode, switching automatically between MS and MS/MS.
T75 13725-13911 Sentence denotes A full MS scan ranging from 350 to 1300 m/z was conducted at 70 000 resolution with an automatic gain control (AGC) target value of 3 × 106 ions and a maximum ion transfer (IT) of 20 ms.
T76 13912-14225 Sentence denotes The precursor ions were fragmented by means of high-energy collisional dissociation (HCD), and all MS/MS spectra were scanned using the following parameters: resolution 17 500; AGC 1 × 105 ions; maximum IT 50 ms; dynamic exclusion duration 18 s; normalized collision energy 30%; and intensity threshold 1.6 × 105.
T77 14227-14248 Sentence denotes 2.7 MS Data Analysis
T78 14249-14380 Sentence denotes The original MS/MS raw data were analyzed using the Proteome Discoverer Software 2.1 (Thermo Fisher Scientific, San Jose, CA, USA).
T79 14381-14550 Sentence denotes The data were searched against the database of UniProt Sus scrofa (February 26, 2017, containing 26 103 sequences, http://www.uniprot.org/proteomes/UP000008227, version:
T80 14551-14768 Sentence denotes Uniprot-proteome-UP000008227-Sus scrofa (Pig)-26103s-20170226.fasta) and porcine deltacoronavirus Uniprot database (February 26, 2017, containing 442 sequences, http://www.uniprot.org/porcinedeltacoronavirus, version:
T81 14769-14833 Sentence denotes Uniprot-Porcine deltacoronavirus [1586324]-442s-20170226.fasta).
T82 14834-15281 Sentence denotes The parameters for database searching were set as follows: instrument, TripleTOF 5600; cysteine alkylation, iodoacetamide; digestion, trypsin; dynamic modification, oxidation (M), acetylation (protein N-terminus), and iTRAQ8plex (Y); static modification, iTRAQ8plex (K), iTRAQ8plex (N-terminus), and carbamidomethyl (C); maximum missed cleavages, 2; precursor mass tolerance, 10 ppm; fragment mass tolerance, 0.05 Da; validation based on, q-value.
T83 15282-15520 Sentence denotes To guarantee the accuracy of the MS data analysis, the cutoff value for the peptide and protein confidences was set to >95% and >1.20, respectively, coupled with a false discovery rate (FDR) of ≤1% for peptide and protein identifications.
T84 15521-15886 Sentence denotes The t test function in the R language software was applied to calculate the p-value of the expression difference of cellular proteins between mock- and PDCoV-infected IPEC-J2 cells, and only proteins with a fold change >1.20 or <0.83 and a p-value < 0.05, which have being widely used as the criteria for judging DEPs,28,29 were considered differentially expressed.
T85 15888-15916 Sentence denotes 2.8 Bioinformatics Analysis
T86 15917-16211 Sentence denotes The data for the identified DEPs of PDCoV-infected IPEC-J2 cells were submitted to Gene Ontology (GO) Terms (http://geneontology.org/) for GO analysis, by which the DEPs were assigned into three branches of ontology—biological process (BP), cellular component (CC), and molecular function (MF).
T87 16212-16426 Sentence denotes GO enrichment analysis for the DEPs was done using the Goatools software (https://github.com/tanghaibao/GOatools) with Fisher’s exact test, and those with a p-value < 0.05 were thought to be significantly enriched.
T88 16427-16588 Sentence denotes The protein database of clusters of Orthologous Groups (COG; http://www.ncbi.nlm.nih.gov/COG/) was also used to assign possible functions to the identified DEPs.
T89 16589-16895 Sentence denotes The Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) pathway analyses were performed to reveal the potential functions of the DEPs, which were annotated using the BlastP program of the Diamond software against the KEGG database with a cutoff E-value ≤ 1 × 10–5 and identity ≥0.98.
T90 16896-17366 Sentence denotes The pathway enrichment statistics were performed using the KOBAS software (http://kobas.cbi.pku.edu.cn/home.do/) with the Fisher’s exact test, and those with p-values < 0.05 were regarded as statistically significant.30,31 Furthermore, the protein–protein interaction networks were created using the online STRING database (http://string-db.org/) and visualized by Cytoscape (https://cytoscape.org/), which was widely used for analyzing the relationships between DEPs.32
T91 17368-17406 Sentence denotes 2.9 Quantitative Real-Time PCR (qPCR)
T92 17407-17587 Sentence denotes To verify the DEPs identified by iTRAQ at the transcriptional level, the mRNA of two representative DEPs, the downregulated ANAPC7 and the upregulated IFIT1, were detected by qPCR.
T93 17588-17739 Sentence denotes Total cellular RNA of both PDCoV- and mock-infected IPEC-J2 cells was extracted using the TaKaRa MiniBEST universal RNA extraction kit (Dalian, China).
T94 17740-17920 Sentence denotes The first strand cDNA was synthesized using 2 μg of cellular RNA and with a RevertAid First Strand cDNA Synthesis Kit (Thermo Scientific) following the manufacturer’s instructions.
T95 17921-18069 Sentence denotes The qPCR assays were conducted using a TaKaRa SYBR Premix Ex Taq kit on an ABI 7500 real-time PCR machine along with β-actin as a housekeeping gene.
T96 18070-18274 Sentence denotes The primers used for the qPCR assay were designed based on the NCBI reference sequences for ANAPC7, IFIT1 and β-actin genes under GenBank accession numbers NM_016238, HQ679904 and NM_001101, respectively.
T97 18275-18350 Sentence denotes The information for the designed primers was as following: ANAPC7 (Forward:
T98 18351-18387 Sentence denotes 5′-CTTTGCTGAGGAACGCACTG-3′, Reverse:
T99 18388-18432 Sentence denotes 5′-TCCATGTCGTCCACATCCTC-3′); IFIT1 (Forward:
T100 18433-18474 Sentence denotes 5′-GAAGATTTAACCCAACAAGAACATA-3′, Reverse:
T101 18475-18526 Sentence denotes 5′-CTTTCGATACGTAAGGTAATACAGC-3′); β-actin (Forward:
T102 18527-18563 Sentence denotes 5′-TCCCTGGAGAAGAGCTACGA-3′, Reverse:
T103 18564-18592 Sentence denotes 5′-AGCACTGTGTTGGCGTACAG-3′).
T104 18593-18802 Sentence denotes The qPCR assays were carried out in a 20-μL reaction volume comprised 10 μL of TaKaRa SYBR Premix Ex Taq, 0.4 μL of each forward and reverse primer (10 μM), 7.2 μL of nuclease-free water, and 2 μL of template.
T105 18803-19039 Sentence denotes The qPCR amplifications were carried out using a thermal profile with an initial step at 95 °C for 2 min, followed by 40 cycles of 95 °C for 10 s, 60 °C for 10 s (for ANAPC7 and β-actin) or 55 °C for 10 s (for IFIT1) and 72 °C for 40 s.
T106 19040-19151 Sentence denotes Fold-change values were calculated in term of the 2–ΔΔCt method and normalized to the β-actin reference gene.33
T107 19153-19180 Sentence denotes 2.10 Western Blot Analysis
T108 19181-19339 Sentence denotes To further validate the identified DEPs, Western blot was performed to detect ANAPC7 and IFIT1 protein expression levels using β-actin as an internal control.
T109 19340-19447 Sentence denotes Briefly, total cellular proteins were extracted from both mock- and PDCoV-infected IPEC-J2 cells at 24 hpi.
T110 19448-19691 Sentence denotes The resulting protein samples were separated on 12% SDS-PAGE gels and transferred onto 0.22 μm poly(vinylidene fluoride) (PVDF) membranes (Millipore, Bedford, MA, USA) using a semidry electrophoretic transfer cell (Bio-Rad, Hercules, CA, USA).
T111 19692-19899 Sentence denotes The membranes were blocked with 5% (w/v) nonfat dry milk overnight at 4 °C and then probed with either anti-ANAPC7 (1:1000), anti-IFIT1 (1:1000), or anti-β-actin (1:5000) primary antibodies at 37 °C for 1 h.
T112 19900-20048 Sentence denotes After thorough washing with PBST, the membranes were incubated with the corresponding HRP-conjugated secondary antibodies (1:8000) for 1 h at 37 °C.
T113 20049-20275 Sentence denotes The target protein blots on the membranes were developed with an enhanced chemiluminescence detection kit (Thermo Fisher Scientific), and images were taken using a ProteinSimple FluorChem E image system (Santa Clara, CA, USA).
T114 20277-20300 Sentence denotes 2.11 Data Availability
T115 20301-20559 Sentence denotes The proteomics data obtained by LC-MS/MS in this study were deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) by means of the Proteomics Identifications (PRIDE) partner repository with the data set identifier PXD019975.
T116 20561-20587 Sentence denotes 2.12 Statistical Analysis
T117 20588-20787 Sentence denotes The methods used for the statistical analysis of proteomic data and the corresponding threshold criteria were described in detail in the corresponding sections of MS data and bioinformatics analyses.
T118 20788-21000 Sentence denotes The data from three independent qPCR runs were expressed as means ± standard deviation (SD), and were statistically analyzed by Student’s t test using the GraphPad Prism software (Version 5.0; La Jolla, CA, USA).
T119 21001-21079 Sentence denotes Differences with a value of p < 0.05 were regarded as statistically different.
T120 21081-21091 Sentence denotes 3 Results
T121 21093-21153 Sentence denotes 3.1 Determination of the Optimal Inoculation Dose for PDCoV
T122 21154-21401 Sentence denotes To obtain the optimal inoculation dose that could produce DEPs to the greatest extent, IPEC-J2 cells were inoculated with PDCoV at low, medium, and high MOIs (i.e., 0.01, 0.1, and 1 TCID50/cell, respectively) for 36 h before the formal experiment.
T123 21402-21582 Sentence denotes By observing the CPE, we found that the high MOI resulted in a rapid synchronous infection of all the cells, causing majority of the cells detached and disintegrated within 12 hpi.
T124 21583-21656 Sentence denotes This is not conducive to the interaction between the virus and the cells.
T125 21657-21841 Sentence denotes By contrast, the cells inoculated with the low MOI only displayed minimal CPEs at the same time points, which might induce limited changes in the expression levels of diverse proteins.
T126 21842-21960 Sentence denotes Therefore, the medium MOI of 0.1 was selected as the optimal dose for PDCoV inoculation in all subsequent experiments.
T127 21962-22055 Sentence denotes 3.2 Selection of the Best Sampling Time for the Proteomic Analysis Following PDCoV Infection
T128 22056-22278 Sentence denotes In order to determine the optimal time point for the proteomic analysis following PDCoV infection, IPEC-J2 cells were inoculated with PDCoV at an MOI of 0.1 and microscopically observed for CPE at 4, 8, 12, 24, and 36 hpi.
T129 22279-22424 Sentence denotes Meanwhile, the cell supernatants at the same time points were collected and used to measure the proliferation dynamics of PDCoV in IPEC-J2 cells.
T130 22425-22605 Sentence denotes Compared to mock-infected cells, PDCoV-inoculated IPEC-J2 cells began to exhibit slight CPE at 8 hpi, and the CPE gradually became increasingly evident as the infection progressed.
T131 22606-22923 Sentence denotes Obvious CPEs were observed at 12 hpi and became more evident at 24 and 36 hpi, which were characterized by cell rounding, enlarging, and granular degeneration of the cytoplasm that occurred either singly or in different-sized clusters, usually forming cell masses, followed by cell shrinkage and increased detachment.
T132 22924-23189 Sentence denotes These CPEs were in agreement with those reported by Jung et al.,8 and resembled those observed in PDCoV-infected swine testicular (ST) and LLC-PK1 cells.34 However, from 36 hpi onward, the majority of the cells became detached and floated in the medium (Figure 1A).
T133 23190-23402 Sentence denotes The proliferation of PDCoV in IPEC-J2 cells was verified by IFA using a mAb raised against the PDCoV nucleocapsid protein, and the results demonstrated that almost all cells became infected at 24 hpi (Figure 1B).
T134 23403-23573 Sentence denotes The one-step growth curve further revealed that the virus titer reached a plateau of ∼107.5 TCID50/mL at 24 hpi, followed by a gradual and continuous decline (Figure 1C).
T135 23574-23927 Sentence denotes In general, the time point at which viral proliferation stays high but no obvious cellular membrane or cytoskeleton rearrangement occurs is the optimal sampling time for a proteomic analysis.22 On the basis of the above experimental results, we therefore chose 24 hpi as the optimal time point for the proteomic analysis of PDCoV-infected IPEC-J2 cells.
T136 23928-24154 Sentence denotes Figure 1 Proliferation of PDCoV in IPEC-J2 cells. (A) Morphological changes in IPEC-J2 cells infected with the PDCoV CHN-HN-1601 strain at an MOI of 0.1 TCID50/cell or mocked infected for 4, 8, 12, 24, and 36 h, respectively.
T137 24155-24417 Sentence denotes Scale bars, 10 μm. (B) Confirmation of PDCoV proliferation in IPEC-J2 cells by immunofluorescence assays using the mAb 1A3 specific for PDCoV (α-N) and an Alexa Fluor 488-labeled goat antimouse IgG, and mock-infected cells at 24 h was used as a negative control.
T138 24418-24467 Sentence denotes Cell nuclei were counterstained with DAPI (blue).
T139 24468-24594 Sentence denotes Scale bars, 10 μm. (C) One-step growth curve of PDCoV in IPEC-J2 cells at the indicated time points following viral infection.
T140 24595-24718 Sentence denotes The titer of virus was presented as TCID50/mL, and the data were recorded as means ± SD from three independent experiments.
T141 24720-24795 Sentence denotes 3.3 Identification of DEPs of IPEC-J2 Cells in Response to PDCoV Infection
T142 24796-25017 Sentence denotes To identify the DEPs following viral infection, the total cellular proteins extracted from PDCoV- and mock-infected IPEC-J2 cells were processed for quantitative proteomics research using iTRAQ-coupled LC-MS/MS technique.
T143 25018-25146 Sentence denotes In all, 5502 cellular proteins were identified in both PDCoV- and mock-infected IPEC-J2 cells at 24 hpi (Supplementary File S1).
T144 25147-25430 Sentence denotes On the basis of the widely used criteria for judging DEPs (fold changes >1.2 or <0.83 and with p < 0.05),28,29 23 proteins were significantly upregulated and 55 proteins were markedly downregulated in PDCoV-infected IPEC-J2 cells in comparison with the mock-infected cells (Table 1).
T145 25431-25732 Sentence denotes Meanwhile, six viral proteins, including the nucleocapsid protein, spike protein, membrane protein, 3C-like proteinase Nsp5, accessory proteins NS6 and NS7 (Supplementary File S2), were also identified in PDCoV-infected IPEC-J2 cells by searching against the porcine deltacoronavirus Uniprot database.
T146 25733-25959 Sentence denotes In order to ensure the reliability of the obtained proteomic data, three biological replicates of PDCoV- or mock-infected cell samples were collected and three technical replicates were performed during the proteomic analysis.
T147 25960-26125 Sentence denotes The difference was plotted against the percentage of the identified proteins, which suggested that the proteomic data had high credibility (Supplementary Figure S1).
T148 26126-26342 Sentence denotes Notably, due to the fact that the current genome database of pigs is inadequately annotated in comparison to the human genome database, we found six uncharacterized or unassigned proteins among the 78 DEPs (Table 1).
T149 26343-26425 Sentence denotes Therefore, a functional analysis of these proteins warrants further investigation.
T150 26426-26545 Sentence denotes Table 1 Differentially Expressed Proteins Identified by iTRAQ Analysis of IPEC-J2 Cells in Response to PDCoV Infection
T151 26546-26668 Sentence denotes protein name Uniprot accession no. log2 ratios (infection/control) peptides sequence coverage (%) p-values functions
T152 26669-26713 Sentence denotes Upregulated proteins in PDCoV-infected cells
T153 26714-26838 Sentence denotes ISG15 ubiqutin-like modifier I3LU39 1.24 18 30.1 3.62 × 10–06 RIG-1/MDA5 mediated induction of IFN-alpha/beta pathways
T154 26839-26935 Sentence denotes Interferon-stimulated protein 60 F1SCY2 1.09 5 14.6 3.51 × 10–05 Defense response to virus
T155 26936-27025 Sentence denotes 2′-5′ oligoadenylates synthetase 1, OAS1 F1RJN6 0.81 2 3.1 0.0001 Antiviral protein
T156 27026-27147 Sentence denotes Radical S-adenosyl methionine domain-containing protein 2 F1S9L2 0.70 6 13.8 1.60 × 10–05 Defense response to virus
T157 27148-27285 Sentence denotes Interferon induced protein with tetratricopeptide repeats 1, IFIT1 K7GN56 0.70 5 9.6 0.0002 Regulation of defense response to virus
T158 27286-27368 Sentence denotes Family with sequence similarity 8 member A1 F1RUH9 0.69 1 2.2 0.0103 unknown
T159 27369-27432 Sentence denotes uncharacterized protein I3LH89 0.658 1 4.7 0.0074 unknown
T160 27433-27562 Sentence denotes Interferon-induced GTP-binding protein Mx1 K7GKN2 0.58 2 2.0 0.0013 GTPase activity; cellular response to type I interferon
T161 27563-27644 Sentence denotes Nucleoporin 37 (NUP37) F1SRJ4 0.57 1 5.2 0.0016 Transporting macromolecules
T162 27645-27767 Sentence denotes Nuclear transcription factor Y submit beta (NFYB) F1SG36 0.55 2 6.3 0.0013 DNA-binding transcription factor activity
T163 27768-27882 Sentence denotes DNA excision repair protein ERCC-6-like isoform a (ERCC6L) I3LFY4 0.45 1 0.8 0.0496 DNA translocase activity
T164 27883-27993 Sentence denotes Collagen type IV alpha 1 chain F1RLM1 0.45 1 0.6 0.0153 Component of glomerular basement membranes (GBM)
T165 27994-28064 Sentence denotes Ribouclease T2 F1SBX8 0.35 2 4.4 0.0004 Ribinuclease T2 activity
T166 28065-28115 Sentence denotes MRPL32 I3LTC4 0.34 1 11.7 0.0472 translation
T167 28116-28177 Sentence denotes Phostensin Q767M0 0.32 3 6.8 0.0047 Phosphatase binding
T168 28178-28257 Sentence denotes Bridging integrator 1 F1RXZ6 0.32 7 22.7 0.0012 Regulation of endocytosis
T169 28258-28357 Sentence denotes Terpene cyclase/mutase family member I3L7C2 0.29 10 16.7 0.0012 Beta-amyrin synthase activity
T170 28358-28424 Sentence denotes Secretagogin (SCGN) Q06A97 0.28 2 9.4 0.0214 Calcium binding
T171 28425-28563 Sentence denotes Interleukin 13 receptor subunit alpha 2 K7GSC6 0.28 2 14.6 0.0370 Obsolete signal transducer activity and cytokine receptor activity
T172 28564-28655 Sentence denotes FOS-like 1 (FOSL1) F1RU26 0.28 1 6.2 0.0214 DNA-binding transcription factor activity
T173 28656-28750 Sentence denotes Prolactin regulatory element binding F1SED4 0.27 9 10.1 0.0229 GTPase activator activity
T174 28751-28862 Sentence denotes CDK-activating kinase assembly factor MAT1 (MNAT1) F6Q8T7 0.27 1 6.4 0.0076 DNA-dependent ATPase activity
T175 28863-28937 Sentence denotes Intraflagellar transport 81 F1RNN4 0.26 1 3.7 0.0033 Tubulin binding
T176 28938-28984 Sentence denotes Downregulated proteins in PDCoV-infected cells
T177 28985-29087 Sentence denotes Very low density lipoprotein receptor (VLDLR) E7CXS1 –0.27 21 22.8 0.0001 Apolipoprotein binding
T178 29088-29143 Sentence denotes uncharacterized I3LFU8 –0.27 3 5.6 0.0218 unknown
T179 29144-29214 Sentence denotes Myeloid leukemia factor 2 F1SLT1 –0.28 6 15.8 0.0488 DNA-binding
T180 29215-29318 Sentence denotes Helicase-like transcription factor (HLTF) I3LM88 –0.28 1 1.9 0.0254 DNA-dependent ATPase activity
T181 29319-29421 Sentence denotes Ras association domain family member 6 F1RUL8 –0.29 2 5.5 0.0011 Regulation of apoptotic process
T182 29422-29530 Sentence denotes Nucleoside diphosphate kinase 7 (NME7) F1RPV8 –0.29 3 8.0 0.0279 Synthesis of nucleoside triphosphates
T183 29531-29662 Sentence denotes Bromodomain adjacent to zinc finger domain 2A (BAZ2A) F1SLA2 –0.29 1 1.2 0.0189 Component of the nucleolar remodeling complex
T184 29663-29740 Sentence denotes BMP2 inducible kinase I3LT15 –0.29 1 2.8 0.0319 Protein kinase activity
T185 29741-29812 Sentence denotes RNA helicase (DDX55) F1RFL5 –0.29 1 1.5 0.0274 Catalytic activity
T186 29813-29871 Sentence denotes TMEM55B F1S8H7 –0.29 1 3.9 0.0445 Catalytic activity
T187 29872-29979 Sentence denotes Chromatin assembly factor 1 subunit A (CHAF1A) F1S7L7 –0.29 4 5.3 0.0252 Chromo shadow domain binding
T188 29980-30121 Sentence denotes RNA polymerase II subunit A C-terminal domain phosphatase (CTDP1) F1RWS7 –0.29 2 5.5 0.0123 Promoting the activity of RNA polymerase II
T189 30122-30178 Sentence denotes uncharacterized I3LIB8 –0.30 2 14.7 0.0373 unknown
T190 30179-30293 Sentence denotes Intraflagellar transport 172 I3LPC6 –0.30 1 0.69 0.0383 Negative regulation of epithelial cell proliferation
T191 30294-30390 Sentence denotes Myocyte enhancer factor 2D (MEF2D) F1RP31 –0.30 1 1.9 0.0418 Protein dimerization activity
T192 30391-30495 Sentence denotes Poly(ADP-ribose) glycohydrolase F1SDW4 –0.31 1 1.3 0.0355 Poly(ADP-ribose) glycohydrolase activity
T193 30496-30603 Sentence denotes Mitogen-activated protein kinase 4 F1STG5 –0.31 4 4.9 0.0233 Protein serine/threonine kinase activity
T194 30604-30715 Sentence denotes Anaphase promoting complex subunit 7 (ANAPC7) I3L7Q8 –0.31 4 7.9 0.0218 Ubiquitin protein ligase activity
T195 30716-30812 Sentence denotes Transmembrane protein 45A F1SKZ6 –0.31 1 3.6 0.0191 Modulates cancer cell chemosensitivity
T196 30813-30902 Sentence denotes Katanin p60 ATPase-containing subunit A1 I3LVP8 –0.32 2 32.1 0.0181 ATPase activity
T197 30903-30990 Sentence denotes Ubiquitin associated protein 2 (UBAP2) F1SEA5 –0.32 1 1.7 0.0237 Cadherin binding
T198 30991-31126 Sentence denotes Ribosomal RNA adenine dimethylase domain containing 1 F1RHJ0 –0.32 1 2.3 0.0391 rRNA (adenine-N6,N6)-dimethyltransferase activity
T199 31127-31223 Sentence denotes Lemur tyrosine kinase 2 F1RFL2 –0.32 1 1.0 0.0104 Protein serine/threonine kinase activity
T200 31224-31364 Sentence denotes Poly(ADP-ribose) polymerase family member 10 F1RSK9 –0.32 1 1.8 0.0182 K63-linked polyubiquitin modification-dependent protein binding
T201 31365-31460 Sentence denotes CDK9 C9E1C9 –0.32 4 11.0 0.0183 Cyclin-dependent protein serine/threonine kinase activity
T202 31461-31551 Sentence denotes Cystatin C Q0Z8R0 –0.33 2 17.1 0.0282 Cysteine-type endopeptidase inhibitor activity
T203 31552-31673 Sentence denotes Cyclin and CBS domain divalent metal cation transport mediator 2 F1S849 –0.33 1 1.1 0.0173 Adenylnucleotide binding
T204 31674-31778 Sentence denotes Protein-serine/threonine kinase F1S069 –0.34 4 8.2 0.0247 Protein serine/threonine kinase activity
T205 31779-31882 Sentence denotes Aamy domain-containing protein F1S5K2 –0.34 1 2.5 0.0390 Catalytic activity; amino acid transport
T206 31883-32004 Sentence denotes GATOR complex protein WDR24 I3LF05 –0.34 1 1.4 0.0368 Regulation of autophagy; positive regulation of TOR signaling
T207 32005-32109 Sentence denotes CD109 antigen isoform 1 preproprotein K7GKY0 –0.35 18 12.9 0.0105 Endopeptidase inhibitor activity
T208 32110-32214 Sentence denotes Nonspecific serine/threonine protein kinase (AKT2) G9BWQ2 –0.35 7 12.0 0.0310 Transferase activity
T209 32215-32311 Sentence denotes DNA polymerase delta interacting protein 3 (POLDIP3) F1SJQ4 –0.35 3 3.8 0.0287 RNA binding
T210 32312-32401 Sentence denotes Exostosin-like glycosyltransferase 2 F1S568 –0.35 1 3.3 0.0215 Transferase activity
T211 32402-32533 Sentence denotes 4F5 domain-containing protein I3LS25 –0.36 9 42.4 0.0015 Positive regulator of amyloid protein aggregation and proteotoxicity
T212 32534-32669 Sentence denotes Integrator complex subunit 4 (INTS4) F1STY6 –0.37 3 2.4 0.0429 Involved in the small nuclear RNAs (snRNA) U1 and U2 transcription
T213 32670-32751 Sentence denotes Smoothelin-like 2 F1RGN8 –0.37 1 2.7 0.0119 Actin cytoskeleton organization
T214 32752-32853 Sentence denotes Elongation of very long chain fatty acids protein I3L7S8 –0.39 1 21.6 0.0444 Catalytic activity
T215 32854-32909 Sentence denotes uncharacterized I3LBD1 –0.40 1 7.4 0.0085 unknown
T216 32910-33006 Sentence denotes Secretory carrier-associated membrane protein F1SJ46 –0.41 7 13.1 0.0144 Protein transport
T217 33007-33069 Sentence denotes Cadherin 6 F1SP42 –0.42 3 3.7 0.0122 Calcium ion binding
T218 33070-33152 Sentence denotes Superoxide dismutase I3LUD1 –0.43 2 4.9 0.0139 Superoxide dismutase activity
T219 33153-33282 Sentence denotes Probable ribosome biogenesis protein C16orf42 homologue (SMARCA2) F1RFZ6 –0.44 1 4.4 0.0470 Involved in ribosome biogenesis
T220 33283-33422 Sentence denotes Protein zyg-11 homologue B F1S6I1 –0.45 1 3.4 0.0030 Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
T221 33423-33515 Sentence denotes BCL2 interacting protein 3 I3LDJ9 –0.45 2 6.6 0.0009 Protein homodimerization activity
T222 33516-33625 Sentence denotes Alpha-(1,6)-fucosyltransferase (FUT8) F1SA54 –0.47 1 3.3 0.0492 Alpha-(1→6)-fucosyltransferase activity
T223 33626-33724 Sentence denotes Signal peptide peptidase-like 2B F1S8G9 –0.52 2 1.9 0.0190 Protein homodimerization activity
T224 33725-33811 Sentence denotes INTS3 and NABP interacting protein (INTS4) F1SNA6 –0.54 5 12.5 0.0006 DNA repair
T225 33812-33906 Sentence denotes Trypsin domain containing 1 F1SUE6 –0.55 1 1.8 0.0215 Serine-type endopeptidase activity
T226 33907-34027 Sentence denotes UDP-glucose glycoprotein glucosyltransferase 2 F1RP50 –0.62 2 2.3 0.0320 Glycoprotein glucosyltransferase activity
T227 34028-34119 Sentence denotes Phosphatidylglycerophosphate synthase 1 I3LN95 –0.62 1 2.7 0.0440 Calcium ion binding
T228 34120-34189 Sentence denotes Metallothionein-2A P79379 –0.63 9 32.8 0.0017 Metal ion binding
T229 34190-34245 Sentence denotes uncharacterized I3LNY1 –0.66 1 6.5 0.0246 unknown
T230 34246-34310 Sentence denotes Formin-like 1 I3LH80 –0.83 1 1.8 0.0191 Rho GTPase binding
T231 34311-34367 Sentence denotes uncharacterized K7GL96 –1.13 1 10.9 0.0412 unknown
T232 34369-34430 Sentence denotes 3.4 Validation of the DEPs by qPCR and Western Blot Analyses
T233 34431-34609 Sentence denotes To validate the obtained LC-MS/MS data, qPCR was performed to evaluate the transcription levels of two randomly selected DEPs, the downregulated ANAPC7 and the upregulated IFIT1.
T234 34610-34696 Sentence denotes To this end, IPEC-J2 cells were mock-infected or infected with PDCoV at an MOI of 0.1.
T235 34697-34785 Sentence denotes At 24 hpi, total cellular RNA was extracted from the cells and subjected to qPCR assays.
T236 34786-34999 Sentence denotes As shown in Figure 2A, the level of mRNA encoding ANAPC7 and IFIT1 proteins was significantly downregulated and upregulated in PDCoV-infected cells, respectively, as compared to the mock-infected cells (p < 0.05).
T237 35000-35106 Sentence denotes The qPCR results were in agreement with the MS data which were acquired by the iTRAQ approach (Figure 2B).
T238 35107-35326 Sentence denotes For further confirmation of the proteomic data, the expression level of ANAPC7 and IFIT1 proteins in IPEC-J2 cells, which were infected exactly as the aforementioned conditions, was also tested by Western blot analysis.
T239 35327-35432 Sentence denotes To track the progression of PDCoV infection, the mAb 1A3 that specifically recognizes PDCoV was utilized.
T240 35433-35766 Sentence denotes As shown in Figure 2C, compared with the mock-infected IPEC-J2 cells, PDCoV significantly decreased the expression of ANAPC7 protein and its relative ratio to β-actin in the cells, whereas the expression of IFIT1 protein and its relative ratio to β-actin in the cells were significantly increased as a consequence of PDCoV infection.
T241 35767-35893 Sentence denotes The original images of the entire PVDF membranes containing the target Western blots were included in Supplementary Figure S2.
T242 35894-35969 Sentence denotes The Western blot results were also consistent with the MS data (Figure 2D).
T243 35970-36077 Sentence denotes Taken together, these experimental results reveal that our quantitative proteomics data are quite reliable.
T244 36078-36292 Sentence denotes Figure 2 Validation of the LC-MS/MS results by Western blot analysis. (A) Quantitative real-time PCR (qPCR) analysis of the relative mRNA expression level of ANAPC7 and IFIT1 in IPEC-J2 cells upon PDCoV infection.
T245 36293-36425 Sentence denotes IPEC-J2 cells were mock infected or infected with the PDCoV CHN-HN-1601 strain at an MOI of 0.1 TCID50/cell and collected at 24 hpi.
T246 36426-36521 Sentence denotes Total RNA was extracted and reverse-transcribed into cDNA for the subsequent analysis via qPCR.
T247 36522-36624 Sentence denotes Fold-change values were calculated based on the 2–ΔΔCt method, using β-actin as the housekeeping gene.
T248 36625-36876 Sentence denotes Error bars indicate the standard error of three independent experiments (Student’s t test; *p < 0.05). (B) The relative ratio of ANAPC7 and IFIT1 mRNAs normalized to β-actin between PDCoV- and mock-infected cells was calculated based on the qPCR data.
T249 36877-37088 Sentence denotes The iTRAQ ratio (PDCoV/Mock) obtained by MS analysis was simultaneously shown as a comparison. (C) Western blot (WB) analysis of the expression of ANAPC7 and IFIT1 proteins in IPEC-J2 cells upon PDCoV infection.
T250 37089-37197 Sentence denotes IPEC-J2 cells were mock infected or infected with the PDCoV CHN-HN-1601 strain at an MOI of 0.1 TCID50/cell.
T251 37198-37417 Sentence denotes At 24 hpi, the cells were harvested and processed for WB analysis using rabbit anti-ANAPC7, mouse anti-IFIT1 polyclonal antibodies and the mAb 1A3 specific for PDCoV. β-Actin was included as an internal loading control.
T252 37418-37696 Sentence denotes The images shown are representatives of three independent experiments. (D) The optical intensity ratio between the corresponding bands (PDCoV-infected band/Mock band) was measured by densitometric scanning and normalized to the intensity of the β-actin bands in each experiment.
T253 37697-37791 Sentence denotes The iTRAQ ratio (PDCoV/Mock) obtained by MS analysis was simultaneously shown as a comparison.
T254 37793-37834 Sentence denotes 3.5 GO Functional Annotation of the DEPs
T255 37835-38023 Sentence denotes To characterize the DEPs, GO analysis was conducted to annotate the proteins based on three major categories: biological process (BP), cellular component (CC), and molecular function (MF).
T256 38024-39079 Sentence denotes Within the BP category, the proteins were predicted to be involved in 13 biological processes, including immune system process, reproductive process, biological adhesion, multiorganism process, detoxification, multicellular organismal process, developmental process, localization, and so on (Figure 3A; Supplementary File S3), among which those associated with multiorganism process, detoxification, and localization were significantly enriched (Figure 3B); within the CC category, the proteins were predicted to be primarily distributed within 9 different cellular components, such as synapse, extracellular region, membrane, organelle, and cell part (Figure 3A), with the significantly enriched being located in the membrane, organelle and cell part (Figure 3B); and within the MF category, the proteins were predicted to be linked with 8 molecular functions, for instance, structural molecule activity, transporter activity, and antioxidant activity (Figure 3A), but no GO term was identified as significantly enriched within this category (Figure 3B).
T257 39080-39275 Sentence denotes Figure 3 GO functional annotation of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection. (A) GO annotations for the upregulated and downregulated proteins.
T258 39276-39411 Sentence denotes The proteins were annotated into three major categories: biological process (BP), cellular component (CC), and molecular function (MF).
T259 39412-39480 Sentence denotes The abscissa text indicates the name and classification of GO terms.
T260 39481-39721 Sentence denotes The pink and blue columns represent the upregulated and downregulated proteins, respectively, with the number of altered proteins being marked on top of each column. (B) GO enrichment analysis for the upregulated and downregulated proteins.
T261 39722-39796 Sentence denotes The name and classification of each GO term are indicated in the abscissa.
T262 39797-39888 Sentence denotes Each column denotes a GO term, and the height of the column represents the enrichment rate.
T263 39889-40063 Sentence denotes The color implies the significance of the enrichment (p-value), and the darker the color, the more significant the enrichment of the GO term (Fisher’s exact test; *p < 0.05).
T264 40065-40109 Sentence denotes 3.6 COG Function Classification of the DEPs
T265 40110-40216 Sentence denotes To further characterize the DEPs, COG function classification was also applied to categorize the proteins.
T266 40217-40319 Sentence denotes As shown in Figure 4, the DEPs could be further classified into 18 categories (Supplementary File S4).
T267 40320-40884 Sentence denotes Among them, 9 proteins were related to general function prediction only; 8 proteins were involved in transcription; 6 proteins were relevant to signal transduction mechanisms; 5 proteins were associated with protein turnover, posttranslational modification, and chaperones; 4 proteins were linked to vesicular transport, intracellular trafficking, and secretion; 4 proteins were correlated with RNA processing and modification; 3 proteins were correlated with chromatin structure and dynamics; 3 proteins were associated with carbohydrate transport and metabolism.
T268 40885-41214 Sentence denotes Seven proteins were respectively related to one of the following biological functions: nucleotide transport and metabolism; lipid transport and metabolism; translation, ribosomal structure, and biogenesis; cell wall/membrane/envelope biogenesis; inorganic ion transport and metabolism; extracellular structures; and cytoskeleton.
T269 41215-41303 Sentence denotes Notably, another 7 proteins related to unknown function were also identified (Figure 4).
T270 41304-41434 Sentence denotes Therefore, further investigation concentrating on the function of these cellular proteins is certainly worth trying in the future.
T271 41435-41566 Sentence denotes Figure 4 COG function classification of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection.
T272 41567-41732 Sentence denotes The capital letters in abscissa denote the COG categories as marked on the right of the histogram and the ordinate indicates the number of proteins in each category.
T273 41734-41772 Sentence denotes 3.7 KEGG Pathway Analysis of the DEPs
T274 41773-42151 Sentence denotes To explore the underlying signaling pathways existing among the identified DEPs, KEGG pathway analyses were done to draw pathway maps.35 As shown in Figure 5A, the 78 identified DEPs were involved in 26 pathways, among which the top 5 involving more than three proteins were related to viral infectious diseases, signal transduction, immune system, digestive system and cancers.
T275 42152-42400 Sentence denotes All the DEPs could be further classified into 6 KEGG pathway categories, including organismal systems, metabolism, human diseases, genetic information processing, environmental information processing, and cellular processes (Supplementary File S5).
T276 42401-42516 Sentence denotes For the upregulated proteins, the top 20 relevant pathways were illustrated in Figure 5B and Supplementary File S6.
T277 42517-42669 Sentence denotes The signaling pathways of interest included the RIG-I-like receptor signaling pathway, PI3K-AKT signaling pathway, endocytosis, pathways in cancer, etc.
T278 42670-42785 Sentence denotes For the downregulated proteins, the top 20 relevant pathways were displayed in Figure 5C and Supplementary File S7.
T279 42786-42880 Sentence denotes The signaling pathways of interest included the mTOR, MAPK, FoxO signaling pathways and so on.
T280 42881-43037 Sentence denotes Interestingly, one upregulated protein (Secretagogin) and one downregulated protein (AKT2) were simultaneously involved in Fc gamma R-mediated phagocytosis.
T281 43038-43190 Sentence denotes To further explore the possible involvement of the identified DEPs in the underlying signaling pathways, KEGG pathway enrichment analysis was performed.
T282 43191-43619 Sentence denotes Our data demonstrated that the DEPs were primarily involved in the HIF-1 signaling pathway, HTLV-I infection, human papillomavirus infection, AGE-RAGE signaling pathway in diabetic complications, central carbon metabolism in cancer, influenza A, measles, Fc gamma R-mediated phagocytosis, small cell lung cancer, glycosaminoglycan biosynthesis, progesterone-mediated oocyte maturation, and relaxin signaling pathway (Figure 5D).
T283 43620-43810 Sentence denotes These signaling pathways were mainly distributed in four distinct functional categories: environmental information processing, human diseases, metabolism, and organismal systems (Figure 5D).
T284 43811-44013 Sentence denotes Figure 5 KEGG pathway analysis of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection. (A) KEGG pathway classification of the 78 differentially expressed proteins.
T285 44014-44311 Sentence denotes The ordinate text indicates the name of biological functions which were classified into 6 KEGG pathway categories, including organismal systems (OS), metabolism (M), human diseases (HD), genetic information processing (GIP), environmental information processing (EIP), and cellular processes (CP).
T286 44312-44613 Sentence denotes The abscissa displays the number of proteins in each category. (B) The top 20 significant pathways of the significantly upregulated proteins. (C) The top 20 significant pathways of the significantly downregulated proteins. (D) KEGG pathway enrichment analysis of the differentially expressed proteins.
T287 44614-44690 Sentence denotes The abscissa text displays the name and classification of the KEGG pathways.
T288 44691-44782 Sentence denotes Each column represents a pathway, and the height of the column implies the enrichment rate.
T289 44783-44959 Sentence denotes The color manifests the significance of the enrichment (p-value), and the darker the color, the more significant the enrichment of the pathway (Fisher’s exact test; *p < 0.05).
T290 44961-45014 Sentence denotes 3.8 Protein–Protein Interaction Networks of the DEPs
T291 45015-45176 Sentence denotes To explore the potential protein network connections between the identified DEPs, the web-tool STRING was applied to depict protein–protein interaction networks.
T292 45177-45397 Sentence denotes As shown in Figure 6, the DEPs were mapped to three major functional interaction networks, among which two were tightly connected by a hub protein, ENSSSCG00000000860 (namely NUP37), while the third exists independently.
T293 45398-45746 Sentence denotes For the two tightly connected networks, they were comprised of two groups of strongly interacted proteins, including SCGN-ISG15-OAS1-IFIT1-IFIT3-ANAPC7-NME7, which are associated with innate immunity, and POLDIP3-NUP37-ERCC6L-DDX55-SMARCA2-NFRB-BAZ2A-HLTF-CHAF1A-CDK9-MNAT1-CTDP1-INTS4, which are associated with cell cycle and cellular components.
T294 45747-45889 Sentence denotes Of note, at least five proteins act as hub proteins in these two networks tightly connected, including IFIT1, IFIT3, NUP37, SMARCA2, and CDK9.
T295 45890-46003 Sentence denotes Interestingly, MNAT1 interacted highly with CTDP1 and CDK9, and INTS4 was also well connected to CDK9 (Figure 6).
T296 46004-46204 Sentence denotes For the third network, there were five proteins with strong interaction in response to PDCoV infection, including MEF2D, VLDLR, LOC780439, PDK1, and AKT2, which are related to cell death and survival.
T297 46205-46504 Sentence denotes Taken together, these findings further indicate that various functional types of host proteins, various biological functions, and complicated protein networks were affected during PDCoV infection of IPEC-J2 cells, which should provide valuable clues for a better understanding of PDCoV pathogenesis.
T298 46505-46645 Sentence denotes Figure 6 Protein–protein interaction networks of the 78 differentially expressed proteins identified in IPEC-J2 cells upon PDCoV infection.
T299 46646-46757 Sentence denotes The networks were built using the STRING database with a minimum interaction score of 0.4 at medium confidence.
T300 46758-46926 Sentence denotes Each node denotes a protein in the graph; each line is indicative of the interaction between two proteins, and the thicker the line, the closer the mutual relationship.
T301 46927-47011 Sentence denotes The width of the edges represents the predicted strength of functional associations.
T302 47013-47026 Sentence denotes 4 Discussion
T303 47027-47754 Sentence denotes The interactions between host cells and viruses are highly complex, which usually involves numerous alterations in the expression of diverse genes, mRNAs, and proteins.36,37 Deciphering the laws behind these changes over the course of viral infection plays a vital role in elucidating the pathogenic mechanisms and in developing efficacious antiviral strategies.37 Over the past decade, MS-based proteomic techniques have contributed significantly to uncovering more factors and mechanisms related to viral infections and the corresponding host cellular pathophysiological processes.18 However, no research to date has focused on differential proteomic analysis of global protein profiles in host cells upon infection by PDCoV.
T304 47755-47861 Sentence denotes In this study, iTRAQ combined with LC-MS/MS was used to identify the DEPs in PDCoV-infected IPEC-J2 cells.
T305 47862-48299 Sentence denotes Although various cell lines including ST, LLC-PK1, PK-15, and IPI-2I cells have been shown to be highly permissive to PDCoV infection,17,34,38 considering porcine enterocytes are the natural targets for PDCoV infection in vivo,8,9 we chose to use IPEC-J2 cells for the proteomic analysis with the goal of obtaining experimental data that could better reflect the physiological state of pigs and the true state of PDCoV infection in vivo.
T306 48300-48484 Sentence denotes Ultimately, a total of 78 DEPs were identified in PDCoV-infected IPEC-J2 cells, among which 23 proteins were significantly upregulated and 55 proteins were significantly downregulated.
T307 48485-48606 Sentence denotes Moreover, we also identified six viral proteins including the spike, membrane, nucleocapsid, NS6, NS7, and Nsp5 proteins.
T308 48607-48831 Sentence denotes To ensure the reliability of the DEPs identified in the present study, we used qPCR and Western blot to validate two randomly selected DEPs, ANAPC7 and IFIT1, at the transcription and protein expression levels, respectively.
T309 48832-49226 Sentence denotes In brief, ANAPC7 is an important constituent of the anaphase promoting complex/cyclosome, which is an E3 ubiquitin ligase that regulates the temporal progression of eukaryotic cells by mediating ubiquitination and subsequent 26S proteasome-mediated degradation of key cell cycle regulators.39 The downregulation of ANAPC7 is indicative of dysfunction of IPEC-J2 cells caused by PDCoV infection.
T310 49227-49555 Sentence denotes IFIT1 is an innate immune effector molecule that can directly recognize viral single-stranded RNAs carrying a 5′-triphosphate group, thereby inhibiting the expression of viral mRNA.40 The upregulation of IFIT1 reveals that innate immune responses were activated in PDCoV-infected IPEC-J2 cells to combat with the invading virus.
T311 49556-49727 Sentence denotes Through the validation of these two DEPs, we found that the obtained proteomics data were reliable and valid, and thus suitable for the subsequent bioinformatics analysis.
T312 49728-49840 Sentence denotes First, we made an attempt to assign possible functions to the 78 identified DEPs using GO functional annotation.
T313 49841-50196 Sentence denotes This tool is an internationally standardized system for gene function classification, which provides a dynamic, updated, controlled vocabularies or ontologies and can well interpret the characteristics of target genes and gene products in various organisms.41 The proteins of our interest involving in different biological functions are listed as follows.
T314 50197-50360 Sentence denotes Five type I interferon (IFN)-inducible proteins, ISG15, OAS1, Mx1, IFIT1, and IFIT3, were clustered into the BP category associated with the immune system process.
T315 50361-50531 Sentence denotes Another five cell cycle-regulating proteins, ERCC6L, NME7, NFYB, FOSL1, and CTDP1, were also classified into the BP category but associated with the reproductive process.
T316 50532-50898 Sentence denotes The nucleolar remodeling complex-constituting protein BAZ2A and the calcium ion binding protein secretagogin were clustered into the same CC category related to synapse.42,43 The apolipoprotein binding protein VLDLR and the cell cycle control and progression-related protein CDK9 were also divided into the CC category but associated with the macromolecular complex.
T317 50899-51102 Sentence denotes In addition, three proteins, FOSL1, NUP37, and DDX55, were annotated to be associated with structural molecule activity, transporter activity and catalytic activity, respectively, within the MF category.
T318 51103-51398 Sentence denotes For further functional annotation of the DEPs, we took a step further by performing COG function classification, which is a widely used tool for analyzing the function and evolution of proteins at the genome scale.44,45 We discovered that most of the DEPs were assigned new biological functions.
T319 51399-51914 Sentence denotes For example, the immune system process-related proteins ISG15, OAS1, IFIT1, and IFIT3 categorized by GO functional annotation, were assigned to be involved in signal transduction mechanisms within the COG function classification; the proteins DDX55, SMARCA2, and ERCC6L belonging to three different GO categories were categorized into the same COG category—chromatin structure and dynamics; and the proteins NFYB, FOSL1, and CTDP1 belonging to the same GO category were still in the same COG category—transcription.
T320 51915-52076 Sentence denotes The aforementioned findings suggested that there exist slight discrepancies in the classification of some proteins between the GO and COG functional annotations.
T321 52077-52210 Sentence denotes This phenomenon is not unanticipated because the two functional annotation tools are based on different classification criteria.41,44
T322 52211-52534 Sentence denotes Next, we made an effort to identify the potential signaling pathways that might exist among the DEPs using KEGG pathway analysis, an extensively used method for the integration and interpretation of high-throughput proteomic and genomic data.35,46,47 We found that the DEPs were related to multitudinous signaling pathways.
T323 52535-53113 Sentence denotes The top five pathways containing ≥4 DEPs included the viral infectious disease pathway, which is involved in eight proteins AKT2, IFIT1, RSAD2, NFYB, ANAPC7, COL4A1, Mx1, and ISG15; the signal transduction pathway, which is involved in six proteins AKT2, BNIP3, PDK1, WDR24, TMEM55B, and COL4A1; the immune system pathway, which is involved in four proteins ISG15, IFIT1, OAS1 and IFIT3; the digestive system pathway, which is involved in four proteins AKT2, MT-2A, COL4A1, and cystatin C; and the cancer pathway, which is involved in four proteins PDK1, AKT2, COL4A1, and CDK9.
T324 53114-53205 Sentence denotes Once again, we found that the same protein can participate in different signaling pathways.
T325 53206-53410 Sentence denotes For instance, ISG15, a IFN-α-inducible protein that is paramount to the host antiviral innate immunity,48 was simultaneously involved in two signaling pathways—viral infectious diseases and immune system.
T326 53411-53784 Sentence denotes IFIT1 (also named p56/ISG56), an innate nucleic acid immune-sensing receptor that can recognize single-stranded viral RNA lacking 2′-O-methylation at the 5′-terminus and thus confers antiviral defense function by disrupting the machinery of host translation initiation,49,50 was also simultaneously related to viral infectious diseases and immune system signaling pathways.
T327 53785-54011 Sentence denotes By contrast, COL4A1, also known as type IV collagen alpha 1 chain, was simultaneously involved in four of the top five signaling pathways, including viral infectious disease, signal transduction, digestive system, and cancers.
T328 54012-54282 Sentence denotes This protein is an integral component of basement membranes, which can inhibit the migration, proliferation and tube formation by endothelial cells via binding to α-1/β-1 integrin, and thus becomes a potential therapeutic candidate for targeting tumor angiogenesis.51,52
T329 54283-54399 Sentence denotes Other interesting signaling pathways included RIG-I-like receptor, PI3K-AKT, mTOR, and autophagy signaling pathways.
T330 54400-54986 Sentence denotes As an important family of cytosolic pattern recognition receptors, RIG-I is responsible for sensing of the invading viral RNA by recognizing its pathogen-associated molecular patterns to activate downstream signaling cascades, and thereby produce type I IFN.53,54 The generated IFN molecules then bind to IFN receptors and activate numerous ISGs, which exert critical antiviral innate immune functions either directly or indirectly.55 In our study, five upregulated proteins encoded by ISGs, including ISG15, OAS1, Mx1, IFIT1, and IFIT3, were identified in PDCoV-infected IPEC-J2 cells.
T331 54987-55197 Sentence denotes Although these proteins related to type I IFN induction have been reported to participate in diverse viral infections,22,56 most of them were identified for the first time to be associated with PDCoV infection.
T332 55198-55315 Sentence denotes These data suggest that the canonical IFN signaling pathways were activated in IPEC-J2 cells upon infection by PDCoV.
T333 55316-55698 Sentence denotes This was further confirmed by a recent transcriptome-level study which also demonstrated that the RIG-I-like receptor signaling pathway was activated in PDCoV-infected cells, even though a different type of cells, PK-15, was used.17 Nevertheless, there is increasing evidence suggesting that PDCoV has evolved multiple escape strategies to interfere with the host’s innate immunity.
T334 55699-56292 Sentence denotes For example, the nsp15 of PDCoV was found to be able to antagonize IFN-β production in LLC-PK1 cells by disrupting the phosphorylation and nuclear translocation of nuclear factor-κB p65 subunit, which is independent of its endoribonuclease activity.57 The Nsp5 of PDCoV was demonstrated to suppress the production of type I IFNs by cleaving the signal transducer and activator of transcription 2, depending on its protease activity.58 Moreover, the PDCoV accessory protein NS6 was shown to antagonize IFN-β production by disrupting the binding of double-stranded RNA to RIG-I/MDA5 receptors.59
T335 56293-57738 Sentence denotes Except for the RIG-I-like signaling pathway, two multifunctional signaling pathways, PI3K-AKT and mTOR, were also activated in PDCoV-infected IPEC-J2 cells, both of which participate in regulating autophagy.60 The PI3K-AKT signaling pathway could be triggered by numerous factors and regulates a variety of fundamental cellular functions, for instance, proliferation and survival.61 Activated AKT subsequently modulates numerous cellular processes, including cellular autophagy, cell cycle progression and cellular survival.62 The mTOR signaling pathway is involved in regulating diverse basic biological processes, including lipid biogenesis, protein synthesis, regulation of autophagy, cytoskeletal organization and so on,63,64 whose dysfunction has been associated with the pathophysiology of many diseases like diabetes and cancer.65 Although the mTOR and PI3K-AKT signaling pathways are able to negatively and positively regulate autophagy, respectively, in an independent manner,60,66−68 they usually coregulate autophagy via merging into a single PI3K-AKT-mTOR signaling pathway, which serves as one of the classical pathways for negatively regulating autophagy.69,70 From the KEGG analysis, we noticed that the PI3K-AKT and mTOR signaling pathways were respectively upregulated and downregulated in PDCoV-infected IPEC-J2 cells, which are the two important indicators of autophagic activation through the PI3K-AKT-mTOR signaling pathway.
T336 57739-57836 Sentence denotes Accordingly, we speculate that PDCoV infection successfully activated autophagy in IPEC-J2 cells.
T337 57837-58005 Sentence denotes Our speculation was in agreement with a recent research which revealed that PDCoV infection triggered autophagy in LLC-PK1 cells,71 despite using a different cell line.
T338 58006-58244 Sentence denotes Undoubtedly, further studies are definitely needed to confirm the autophagy induced by PDCoV infection, to analyze the impact of autophagy on viral replication and to explore the underlying molecular mechanisms of PDCoV-induced autophagy.
T339 58245-58419 Sentence denotes It should be noted that the PI3K-AKT-mTOR signaling pathway also plays an important role in many physiological and pathological conditions,69 except for regulating autophagy.
T340 58420-58650 Sentence denotes Finally, we sought to uncover the hidden interaction networks among the DEPs using STRING analysis, and discovered three major functional networks consisting of the RIG-I-like receptor, PDK1-AKT2 and cell cycle signaling pathways.
T341 58651-58848 Sentence denotes These findings are in accordance with the results of KEGG pathway analysis, thus further consolidating the credibility of these putative signaling pathways involved in PDCoV-infected IPEC-J2 cells.
T342 58849-58976 Sentence denotes Given the former two signaling pathways have already been discussed earlier, we next focus on the cell cycle signaling pathway.
T343 58977-59164 Sentence denotes As can be seen from the network diagram (Figure 6), three small networks with NUP37, SMARCA2, and CDK9 as the respective hub proteins together constitute the cell cycle signaling pathway.
T344 59165-60519 Sentence denotes NUP37 is an important constituent of the nuclear pore Nup107–160 subcomplex, which controls the bidirectional trafficking of macromolecules that traverse the nuclear envelope.72 SMARCA2 is an important member of the SWI/SNF family with helicase and ATPase activities, and has been shown to regulate numerous biological processes such as cell proliferation and DNA repair.73 CDK9 paired with cyclin T1 forms the positive transcription elongation factor b (p-TEFb) complex and induces transcriptional activation by hyperphosphorylating RNA polymerase II, and thereby regulating numerous vital cellular functions including proliferation, differentiation, DNA repair and apoptosis.74,75 However, growing studies suggest that CDK9 is also related to many pathologic processes, such as cancer, cardiovascular diseases and viral replication.74 Currently, CDK9 has been demonstrated to be involved in the replication of multiple viruses, such as influenza A virus, dengue virus, human adenovirus, and human immunodeficiency virus.75 For example, CDK9 was found to interact with the viral RNA-dependent RNA polymerases of influenza A virus and facilitate its association with cellular RNA polymerase II, thereby promoting viral transcription.76 CDK9 was also shown to be critical for the transcription of viral early genes and the replication of human adenovirus.
T345 60520-60881 Sentence denotes Treatment of host cells with the CDK9 inhibitor, FIT-039, which functions by suppressing mRNA transcription, can efficiently inhibits the replication of human adenovirus.77 In the present study, CDK9 was significantly downregulated in IPEC-J2 cells upon PDCoV infection; however, the biological functions hidden behind this change warrant further investigation.
T346 60882-61167 Sentence denotes Of note, it is of great significance to compare our proteomics data with those of the newly emergent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2),78,79 which caused the Coronavirus Disease 2019 (COVID-19) Pandemic and has posed a serious global public health emergency.
T347 61168-61596 Sentence denotes Recently, Appelberg et al. conducted an integrative proteo-transcriptomics analysis of Huh7 cells responding to SARS-CoV-2 infection, and identified ErbB, HIF-1, mTOR, and TNF signaling pathways that were significantly regulated during SARS-CoV-2 infection in vitro.78 They further demonstrated that the Akt inhibitor MK-2206, targeting the mTOR signaling pathway, was able to significantly reduce the replication of SARS-CoV-2.
T348 61597-62159 Sentence denotes Moreover, another recent study investigated the translatome and proteome of Caco-2 cells in response to SARS-CoV-2 infection in vitro, and discovered that several cellular pathways linked to translation, proteostasis, splicing, carbon metabolism, and nucleotide metabolism were reshaped during viral infection.79 On this basis, the authors tested two translation inhibitors, cycloheximide and emetine, for their ability to suppress SARS-CoV-2 replication, and found that both pharmaceuticals significantly decreased the replication of SARS-CoV-2 in Caco-2 cells.
T349 62160-62534 Sentence denotes Undoubtedly, by comparing the similarities and differences of cellular proteomes between PDCoV- and SARS-CoV-2-infected host cells, it is possible to find some common signaling pathways and key adaptor molecules that function to inhibit viral replication, and thus provide valuable clues for screening of therapeutic drugs for PDCoV and designing novel antiviral strategies.
T350 62536-62550 Sentence denotes 5 Conclusions
T351 62551-62751 Sentence denotes The present study provides the first systematic analysis of the global protein profiles of PDCoV-infected IPEC-J2 cells using a quantitative proteomics approach in which iTRAQ was coupled to LC-MS/MS.
T352 62752-62895 Sentence denotes A total of 78 DEPs, including 23 upregulated proteins and 55 downregulated proteins, were identified in PDCoV-infected IPEC-J2 cells at 24 hpi.
T353 62896-63191 Sentence denotes Bioinformatics analyses further revealed that a majority of the DEPs were involved in various crucial biological processes and signaling pathways, such as digestive system, immune system, signal transduction, and RIG-I-like receptor, mTOR, PI3K-AKT, autophagy, and cell cycle signaling pathways.
T354 63192-63431 Sentence denotes Although further investigations are required to elucidate the functions of the DEPs of interest, our current data provide valuable clues for the in-depth investigation of pathogenic mechanisms of PDCoV and defense mechanisms of host cells.
T355 63433-63465 Sentence denotes Supporting Information Available
T356 63466-63603 Sentence denotes The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00592.Supplementary Figure S1:
T357 63604-63738 Sentence denotes Repeatability analysis of different biological replicates used for iTRAQ-coupled LC–MS/MS proteomic analysis; Supplementary Figure S2:
T358 63739-63842 Sentence denotes The original images of the entire PVDF membranes containing the target Western blots of Figure 2C (PDF)
T359 63843-63865 Sentence denotes Supplementary File S1:
T360 63866-63983 Sentence denotes A total of 5502 proteins identified in PDCoV- and mock-infected IPEC-J2 cells using iTRAQ-coupled LC-MS method (XLSX)
T361 63984-64006 Sentence denotes Supplementary File S2:
T362 64007-64071 Sentence denotes Viral proteins identified in PDCoV-infected IPEC-J2 cells (XLSX)
T363 64072-64168 Sentence denotes Supplementary File S3: GO function annotation of the 78 differentially expressed proteins (XLSX)
T364 64169-64270 Sentence denotes Supplementary File S4: COG function classification of the 78 differentially expressed proteins (XLSX)
T365 64271-64366 Sentence denotes Supplementary File S5: KEGG pathway analysis of the 78 differentially expressed proteins (XLSX)
T366 64367-64389 Sentence denotes Supplementary File S6:
T367 64390-64465 Sentence denotes The top 20 KEGG pathway of the 23 significantly upregulated proteins (XLSX)
T368 64466-64488 Sentence denotes Supplementary File S7:
T369 64489-64566 Sentence denotes The top 20 KEGG pathway of the 55 significantly downregulated proteins (XLSX)
T370 64568-64590 Sentence denotes Supplementary Material
T371 64591-64611 Sentence denotes pr0c00592_si_001.pdf
T372 64612-64633 Sentence denotes pr0c00592_si_004.xlsx
T373 64634-64655 Sentence denotes pr0c00592_si_005.xlsx
T374 64656-64677 Sentence denotes pr0c00592_si_006.xlsx
T375 64678-64699 Sentence denotes pr0c00592_si_007.xlsx
T376 64700-64721 Sentence denotes pr0c00592_si_008.xlsx
T377 64722-64743 Sentence denotes pr0c00592_si_009.xlsx
T378 64744-64765 Sentence denotes pr0c00592_si_010.xlsx
T379 64767-64787 Sentence denotes Author Contributions
T380 64788-65029 Sentence denotes Xinrong Zhou performed the experiments; Lei Zhou, Xinna Ge, Xin Guo, Jun Han, and Yongning Zhang analyzed the experimental data; Xinrong Zhou and Yongning Zhang wrote the paper; and Hanchun Yang designed the experiments and edited the paper.
T381 65031-65083 Sentence denotes The authors declare no competing financial interest.
T382 65085-65090 Sentence denotes Notes
T383 65091-65349 Sentence denotes The proteomics data obtained by LC-MS/MS in this study were deposited to the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) by means of the Proteomics Identifications (PRIDE) partner repository with the data set identifier PXD019975.
T384 65351-65366 Sentence denotes Acknowledgments
T385 65367-65701 Sentence denotes This work was funded by the National Key Research and Development Program (2018YFD0500103; http://program.most.gov.cn/) of the Ministry of Science and Technology of the People’s Republic of China, and the China Agriculture Research System (CARS-35) from the Ministry of Agriculture and Rural Affairs of the People’s Republic of China.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 85-109 Species denotes Porcine Deltacoronavirus Tax:1586324
4 35-42 Species denotes Porcine Tax:28344
5 71-79 Disease denotes Infected MESH:D007239
21 898-934 Gene denotes anaphase-promoting complex subunit 7 Gene:51434
22 936-942 Gene denotes ANAPC7 Gene:51434
23 960-1019 Gene denotes interferon-induced protein with tetratricopeptide repeats 1 Gene:3434
24 1021-1026 Gene denotes IFIT1 Gene:3434
25 1434-1438 Gene denotes mTOR Gene:2475
26 1445-1448 Gene denotes AKT Gene:207
27 149-173 Species denotes Porcine deltacoronavirus Tax:1586324
28 214-225 Species denotes coronavirus Tax:11118
29 242-247 Species denotes swine Tax:9823
30 258-265 Species denotes Porcine Tax:28344
31 248-256 Disease denotes diarrhea MESH:D003967
32 345-354 Disease denotes infection MESH:D007239
33 591-605 Disease denotes PDCoV-infected MESH:D007239
34 1548-1562 Disease denotes PDCoV-infected MESH:D007239
35 606-613 CellLine denotes IPEC-J2 CVCL:2246
50 1676-1700 Species denotes Porcine deltacoronavirus Tax:1586324
51 1837-1850 Species denotes Coronaviridae Tax:11118
52 1919-1923 Species denotes pigs Tax:9823
53 2035-2039 Species denotes pigs Tax:9823
54 2307-2311 Species denotes pigs Tax:9823
55 2515-2520 Species denotes swine Tax:9823
56 2013-2031 Disease denotes diarrheal diseases MESH:D004403
57 2056-2071 Disease denotes PDCoV infection MESH:D007239
58 2292-2306 Disease denotes PDCoV-infected MESH:D007239
59 2331-2339 Disease denotes diarrhea MESH:D003967
60 2347-2355 Disease denotes vomiting MESH:D014839
61 2357-2368 Disease denotes dehydration MESH:D003681
62 2374-2379 Disease denotes death MESH:D003643
63 2418-2433 Disease denotes PDCoV infection MESH:D007239
85 2588-2592 Species denotes pigs Tax:9823
86 2620-2624 Species denotes pigs Tax:9823
87 2978-2982 Species denotes pigs Tax:9823
88 3494-3511 Species denotes porcine rotavirus Tax:10913
89 3547-3551 Species denotes PEDV Tax:28295
90 3560-3595 Species denotes transmissible gastroenteritis virus Tax:11149
91 3597-3601 Species denotes TGEV Tax:11149
92 2707-2714 Species denotes porcine Tax:28344
93 3170-3177 Species denotes porcine Tax:28344
94 3250-3257 Species denotes porcine Tax:28344
95 3461-3468 Species denotes porcine Tax:28344
96 3515-3522 Species denotes porcine Tax:28344
97 2847-2862 Disease denotes PDCoV infection MESH:D007239
98 2886-2893 Disease denotes atrophy MESH:D001284
99 2925-2933 Disease denotes necrosis MESH:D009336
100 2969-2977 Disease denotes infected MESH:D007239
101 3531-3539 Disease denotes diarrhea MESH:D003967
102 3699-3708 Disease denotes infection MESH:D007239
103 3030-3037 CellLine denotes IPEC-J2 CVCL:2246
104 3317-3324 CellLine denotes IPEC-J2 CVCL:2246
105 3654-3661 CellLine denotes IPEC-J2 CVCL:2246
110 3739-3744 Species denotes swine Tax:9823
111 3762-3773 Species denotes coronavirus Tax:11118
112 4405-4425 Disease denotes PDCoV-infected PK-15 MESH:C564858
113 4710-4724 Disease denotes PDCoV-infected MESH:D007239
125 5786-5790 Species denotes TGEV Tax:11149
126 5794-5798 Species denotes PEDV Tax:28295
127 5802-5830 Species denotes foot-and-mouth disease virus Tax:12110
128 5832-5836 Species denotes FMDV Tax:12110
129 5841-5866 Species denotes porcine circovirus type 2 Tax:85708
130 5868-5872 Species denotes PCV2 Tax:85708
131 5879-5906 Species denotes classical swine fever virus Tax:11096
132 5908-5912 Species denotes CSFV Tax:11096
133 4825-4841 Disease denotes viral infections MESH:D001102
134 6292-6301 Disease denotes infection MESH:D007239
135 6257-6264 CellLine denotes IPEC-J2 CVCL:2246
149 7517-7522 Gene denotes IFIT1 Gene:15957
150 7539-7545 Gene denotes ANAPC7 Gene:56317
151 7613-7624 Species denotes Horseradish Tax:3704
152 7036-7042 Species denotes bovine Tax:9913
153 7482-7487 Species denotes Mouse Tax:10090
154 7506-7511 Species denotes mouse Tax:10090
155 7493-7500 Gene denotes β-actin Gene:728378
156 7308-7311 Chemical denotes CO2 MESH:D002245
157 7732-7747 Chemical denotes Alexa Fluor 488
158 6457-6474 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
159 6590-6598 Disease denotes diarrhea MESH:D003967
160 7087-7097 Disease denotes mL insulin MESH:D007333
161 6773-6780 CellLine denotes IPEC-J2 CVCL:2246
173 7920-7945 Chemical denotes phosphate buffered saline
174 7947-7950 Chemical denotes PBS
175 8172-8175 Chemical denotes PBS
176 8191-8195 Chemical denotes DMEM
177 8196-8206 Chemical denotes F12 medium
178 7983-7991 Disease denotes infected MESH:D007239
179 7995-8003 Disease denotes infected MESH:D007239
180 8009-8026 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
181 8055-8064 Disease denotes infection MESH:D007239
182 7847-7854 CellLine denotes IPEC-J2 CVCL:2246
183 8399-8406 CellLine denotes IPEC-J2 CVCL:2246
188 8946-8950 Chemical denotes DMEM
189 8951-8961 Chemical denotes F12 medium
190 8631-8638 CellLine denotes IPEC-J2 CVCL:2246
191 8805-8812 CellLine denotes IPEC-J2 CVCL:2246
200 9404-9407 Chemical denotes CO2 MESH:D002245
201 9451-9458 Chemical denotes ethanol MESH:D000431
202 9510-9513 Chemical denotes PBS
203 9640-9655 Chemical denotes Alexa Fluor 488
204 9794-9797 Chemical denotes PBS
205 9296-9304 Disease denotes infected MESH:D007239
206 9308-9316 Disease denotes infected MESH:D007239
207 9213-9220 CellLine denotes IPEC-J2 CVCL:2246
215 10777-10780 Gene denotes kit Gene:3815
216 10086-10089 Chemical denotes PBS
217 10352-10369 Chemical denotes RIPA lysis buffer
218 10412-10415 Chemical denotes SDS MESH:D012967
219 10421-10425 Chemical denotes urea MESH:D014508
220 9986-9994 Disease denotes infected MESH:D007239
221 9995-10002 CellLine denotes IPEC-J2 CVCL:2246
233 12051-12054 Gene denotes kit Gene:3815
234 11173-11190 Chemical denotes RIPA lysis buffer
235 11226-11257 Chemical denotes tris (2-carboxyethyl) phosphine MESH:C080938
236 11259-11263 Chemical denotes TCEP MESH:C080938
237 11353-11366 Chemical denotes iodoacetamide MESH:D007460
238 11528-11535 Chemical denotes acetone MESH:D000096
239 11725-11753 Chemical denotes triethylammonium bicarbonate MESH:C041737
240 11755-11759 Chemical denotes TEAB MESH:C041737
241 11975-11979 Chemical denotes TEAB MESH:C041737
242 12185-12193 Disease denotes infected MESH:D007239
243 12318-12332 Disease denotes PDCoV-infected MESH:D007239
249 13207-13215 Chemical denotes peptides MESH:D010455
250 13342-13353 Chemical denotes formic acid MESH:C030544
251 13367-13379 Chemical denotes acetonitrile MESH:C032159
252 13418-13429 Chemical denotes formic acid MESH:C030544
253 13444-13456 Chemical denotes acetonitrile MESH:C032159
262 14436-14446 Species denotes Sus scrofa Tax:9823
263 14580-14590 Species denotes Sus scrofa Tax:9823
264 14592-14595 Species denotes Pig Tax:9823
265 14624-14648 Species denotes porcine deltacoronavirus Tax:1586324
266 14777-14801 Species denotes Porcine deltacoronavirus Tax:1586324
267 15151-15162 Species denotes C); maximum Tax:13423
268 15673-15687 Disease denotes PDCoV-infected MESH:D007239
269 15688-15695 CellLine denotes IPEC-J2 CVCL:2246
272 15953-15967 Disease denotes PDCoV-infected MESH:D007239
273 15968-15975 CellLine denotes IPEC-J2 CVCL:2246
293 17531-17537 Gene denotes ANAPC7 Gene:51434
294 17558-17563 Gene denotes IFIT1 Gene:3434
295 18038-18045 Gene denotes β-actin Gene:728378
296 18162-18168 Gene denotes ANAPC7 Gene:51434
297 18170-18175 Gene denotes IFIT1 Gene:3434
298 18180-18187 Gene denotes β-actin Gene:728378
299 18334-18340 Gene denotes ANAPC7 Gene:51434
300 18417-18422 Gene denotes IFIT1 Gene:3434
301 18509-18516 Gene denotes β-actin Gene:728378
302 18970-18976 Gene denotes ANAPC7 Gene:51434
303 18981-18988 Gene denotes β-actin Gene:728378
304 19013-19018 Gene denotes IFIT1 Gene:3434
305 17854-17857 Gene denotes Kit Gene:396810
306 17986-17989 Gene denotes kit Gene:396810
307 17719-17722 Gene denotes kit Gene:396810
308 19126-19133 Gene denotes β-actin Gene:728378
309 18774-18779 Chemical denotes water MESH:D014867
310 17631-17639 Disease denotes infected MESH:D007239
311 17640-17647 CellLine denotes IPEC-J2 CVCL:2246
326 19259-19265 Gene denotes ANAPC7 Gene:51434
327 19270-19275 Gene denotes IFIT1 Gene:3434
328 19308-19315 Gene denotes β-actin Gene:728378
329 19667-19670 Gene denotes Rad Gene:6236
330 19800-19806 Gene denotes ANAPC7 Gene:51434
331 19822-19827 Gene denotes IFIT1 Gene:3434
332 20151-20154 Gene denotes kit Gene:3815
333 19846-19853 Gene denotes β-actin Gene:728378
334 19500-19503 Chemical denotes SDS MESH:D012967
335 19543-19568 Chemical denotes poly(vinylidene fluoride) MESH:C024865
336 19570-19574 Chemical denotes PVDF MESH:C024865
337 19408-19422 Disease denotes PDCoV-infected MESH:D007239
338 19740-19748 Disease denotes dry milk MESH:D016269
339 19423-19430 CellLine denotes IPEC-J2 CVCL:2246
342 21471-21492 Disease denotes synchronous infection MESH:D009378
343 21241-21248 CellLine denotes IPEC-J2 CVCL:2246
345 22046-22055 Disease denotes Infection MESH:D007239
358 23037-23042 Species denotes swine Tax:9823
359 22144-22153 Disease denotes infection MESH:D007239
360 22442-22450 Disease denotes infected MESH:D007239
361 22584-22593 Disease denotes infection MESH:D007239
362 23022-23036 Disease denotes PDCoV-infected MESH:D007239
363 23371-23379 Disease denotes infected MESH:D007239
364 23898-23912 Disease denotes PDCoV-infected MESH:D007239
365 22155-22162 CellLine denotes IPEC-J2 CVCL:2246
366 22410-22417 CellLine denotes IPEC-J2 CVCL:2246
367 22475-22482 CellLine denotes IPEC-J2 CVCL:2246
368 23220-23227 CellLine denotes IPEC-J2 CVCL:2246
369 23913-23920 CellLine denotes IPEC-J2 CVCL:2246
382 24298-24301 Chemical denotes α-N
383 24310-24325 Chemical denotes Alexa Fluor 488
384 24455-24459 Chemical denotes DAPI MESH:C007293
385 24022-24030 Disease denotes infected MESH:D007239
386 24040-24057 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
387 24104-24112 Disease denotes infected MESH:D007239
388 24363-24371 Disease denotes infected MESH:D007239
389 24578-24593 Disease denotes viral infection MESH:D001102
390 23964-23971 CellLine denotes IPEC-J2 CVCL:2246
391 24008-24015 CellLine denotes IPEC-J2 CVCL:2246
392 24217-24224 CellLine denotes IPEC-J2 CVCL:2246
393 24525-24532 CellLine denotes IPEC-J2 CVCL:2246
396 24786-24795 Disease denotes Infection MESH:D007239
397 24751-24758 CellLine denotes IPEC-J2 CVCL:2246
415 25550-25554 Gene denotes Nsp5 Gene:92521
416 25583-25586 Gene denotes NS7 Gene:673
417 25575-25578 Gene denotes NS6 Gene:4893
418 25690-25714 Species denotes porcine deltacoronavirus Tax:1586324
419 26187-26191 Species denotes pigs Tax:9823
420 26239-26244 Species denotes human Tax:9606
421 24827-24842 Disease denotes viral infection MESH:D001102
422 24903-24911 Disease denotes infected MESH:D007239
423 25089-25097 Disease denotes infected MESH:D007239
424 25348-25362 Disease denotes PDCoV-infected MESH:D007239
425 25405-25413 Disease denotes infected MESH:D007239
426 25636-25650 Disease denotes PDCoV-infected MESH:D007239
427 25846-25854 Disease denotes infected MESH:D007239
428 24912-24919 CellLine denotes IPEC-J2 CVCL:2246
429 25098-25105 CellLine denotes IPEC-J2 CVCL:2246
430 25363-25370 CellLine denotes IPEC-J2 CVCL:2246
431 25651-25658 CellLine denotes IPEC-J2 CVCL:2246
512 26714-26719 Gene denotes ISG15 Gene:9636
513 26782-26787 Gene denotes RIG-1 Gene:5920
514 26788-26792 Gene denotes MDA5 Gene:64135
515 26815-26829 Gene denotes IFN-alpha/beta Gene:3440
516 27026-27083 Gene denotes Radical S-adenosyl methionine domain-containing protein 2 Gene:91543
517 27148-27207 Gene denotes Interferon induced protein with tetratricopeptide repeats 1 Gene:3434
518 27209-27214 Gene denotes IFIT1 Gene:3434
519 27472-27475 Gene denotes Mx1 Gene:4599
520 27579-27584 Gene denotes NUP37 Gene:79023
521 27689-27693 Gene denotes NFYB Gene:4801
522 27819-27825 Gene denotes ERCC6L Gene:54821
523 27883-27907 Gene denotes Collagen type IV alpha 1 Gene:1282
524 28065-28071 Gene denotes MRPL32 Gene:64983
525 28116-28126 Gene denotes Phostensin Gene:170954
526 28178-28199 Gene denotes Bridging integrator 1 Gene:274
527 28358-28370 Gene denotes Secretagogin Gene:10590
528 28372-28376 Gene denotes SCGN Gene:10590
529 28425-28464 Gene denotes Interleukin 13 receptor subunit alpha 2 Gene:3598
530 28576-28581 Gene denotes FOSL1 Gene:8061
531 28656-28665 Gene denotes Prolactin Gene:5617
532 28751-28793 Gene denotes CDK-activating kinase assembly factor MAT1 Gene:4331
533 28795-28800 Gene denotes MNAT1 Gene:4331
534 28985-29022 Gene denotes Very low density lipoprotein receptor Gene:7436
535 29024-29029 Gene denotes VLDLR Gene:7436
536 29215-29249 Gene denotes Helicase-like transcription factor Gene:6596
537 29251-29255 Gene denotes HLTF Gene:6596
538 29422-29453 Gene denotes Nucleoside diphosphate kinase 7 Gene:29922
539 29455-29459 Gene denotes NME7 Gene:29922
540 29578-29583 Gene denotes BAZ2A Gene:11176
541 29755-29760 Gene denotes DDX55 Gene:57696
542 29813-29820 Gene denotes TMEM55B Gene:90809
543 29872-29909 Gene denotes Chromatin assembly factor 1 subunit A Gene:10036
544 29911-29917 Gene denotes CHAF1A Gene:10036
545 29980-30037 Gene denotes RNA polymerase II subunit A C-terminal domain phosphatase Gene:9150
546 30039-30044 Gene denotes CTDP1 Gene:9150
547 30294-30320 Gene denotes Myocyte enhancer factor 2D Gene:4209
548 30604-30640 Gene denotes Anaphase promoting complex subunit 7 Gene:51434
549 30642-30648 Gene denotes ANAPC7 Gene:51434
550 30903-30933 Gene denotes Ubiquitin associated protein 2 Gene:55833
551 30935-30940 Gene denotes UBAP2 Gene:55833
552 31365-31369 Gene denotes CDK9 Gene:1025
553 31905-31910 Gene denotes WDR24 Gene:84219
554 31991-31994 Gene denotes TOR Gene:6097
555 32005-32010 Gene denotes CD109 Gene:135228
556 32155-32159 Gene denotes AKT2 Gene:208
557 32215-32257 Gene denotes DNA polymerase delta interacting protein 3 Gene:84271
558 32259-32266 Gene denotes POLDIP3 Gene:84271
559 32312-32348 Gene denotes Exostosin-like glycosyltransferase 2 Gene:2135
560 32534-32562 Gene denotes Integrator complex subunit 4 Gene:92105
561 32564-32569 Gene denotes INTS4 Gene:92105
562 33007-33017 Gene denotes Cadherin 6 Gene:1004
563 33190-33198 Gene denotes C16orf42 Gene:115939
564 33210-33217 Gene denotes SMARCA2 Gene:6595
565 33291-33297 Gene denotes zyg-11 Gene:440590
566 33423-33427 Gene denotes BCL2 Gene:596
567 33516-33546 Gene denotes Alpha-(1,6)-fucosyltransferase Gene:2530
568 33548-33552 Gene denotes FUT8 Gene:2530
569 33586-33616 Gene denotes Alpha-(1→6)-fucosyltransferase Gene:2530
570 33626-33658 Gene denotes Signal peptide peptidase-like 2B Gene:56928
571 33725-33730 Gene denotes INTS3 Gene:65123
572 33761-33766 Gene denotes INTS4 Gene:92105
573 34120-34138 Gene denotes Metallothionein-2A Gene:4502
574 31461-31471 Gene denotes Cystatin C Gene:1471
575 30322-30327 Gene denotes MEF2D Gene:4209
576 29745-29753 Gene denotes helicase Gene:164045
577 30571-30577 Chemical denotes serine MESH:D012694
578 31191-31197 Chemical denotes serine MESH:D012694
579 31428-31434 Chemical denotes serine MESH:D012694
580 31682-31688 Chemical denotes serine MESH:D012694
581 31746-31752 Chemical denotes serine MESH:D012694
582 32122-32128 Chemical denotes serine MESH:D012694
583 33872-33878 Chemical denotes Serine MESH:D012694
584 33911-33918 Chemical denotes glucose MESH:D005947
585 26596-26605 Disease denotes infection MESH:D007239
586 26693-26707 Disease denotes PDCoV-infected MESH:D007239
587 28964-28978 Disease denotes PDCoV-infected MESH:D007239
588 29144-29160 Disease denotes Myeloid leukemia MESH:D007951
589 30784-30790 Disease denotes cancer MESH:D009369
590 32519-32533 Disease denotes proteotoxicity
591 31371-31377 CellLine denotes C9E1C9 CVCL:F711
594 26536-26545 Disease denotes Infection MESH:D007239
595 26501-26508 CellLine denotes IPEC-J2 CVCL:2246
618 34576-34582 Gene denotes ANAPC7 Gene:51434
619 34603-34608 Gene denotes IFIT1 Gene:3434
620 34836-34842 Gene denotes ANAPC7 Gene:51434
621 34847-34852 Gene denotes IFIT1 Gene:3434
622 35179-35185 Gene denotes ANAPC7 Gene:100155743
623 35190-35195 Gene denotes IFIT1 Gene:100153038
624 35551-35557 Gene denotes ANAPC7 Gene:51434
625 35592-35599 Gene denotes β-actin Gene:728378
626 35640-35645 Gene denotes IFIT1 Gene:3434
627 35680-35687 Gene denotes β-actin Gene:728378
628 35801-35805 Chemical denotes PVDF MESH:C024865
629 34647-34655 Disease denotes infected MESH:D007239
630 34659-34667 Disease denotes infected MESH:D007239
631 34913-34927 Disease denotes PDCoV-infected MESH:D007239
632 34973-34981 Disease denotes infected MESH:D007239
633 35234-35242 Disease denotes infected MESH:D007239
634 35355-35370 Disease denotes PDCoV infection MESH:D007239
635 35479-35487 Disease denotes infected MESH:D007239
636 35750-35765 Disease denotes PDCoV infection MESH:D007239
637 34623-34630 CellLine denotes IPEC-J2 CVCL:2246
638 35208-35221 CellLine denotes IPEC-J2 cells CVCL:2246
639 35488-35495 CellLine denotes IPEC-J2 CVCL:2246
667 36237-36243 Gene denotes ANAPC7 Gene:100155743
668 36248-36253 Gene denotes IFIT1 Gene:100153038
669 36591-36598 Gene denotes β-actin Gene:728378
670 36754-36760 Gene denotes ANAPC7 Gene:51434
671 36765-36770 Gene denotes IFIT1 Gene:3434
672 36791-36798 Gene denotes β-actin Gene:728378
673 37024-37030 Gene denotes ANAPC7 Gene:100155743
674 37035-37040 Gene denotes IFIT1 Gene:100153038
675 37282-37288 Gene denotes ANAPC7 Gene:56317
676 37301-37306 Gene denotes IFIT1 Gene:15957
677 37365-37372 Gene denotes β-Actin Gene:728378
678 37663-37670 Gene denotes β-actin Gene:728378
679 37290-37295 Species denotes mouse Tax:10090
680 36282-36291 Disease denotes infection MESH:D007239
681 36317-36325 Disease denotes infected MESH:D007239
682 36329-36337 Disease denotes infected MESH:D007239
683 36347-36364 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
684 36823-36831 Disease denotes infected MESH:D007239
685 37078-37087 Disease denotes infection MESH:D007239
686 37113-37121 Disease denotes infected MESH:D007239
687 37125-37133 Disease denotes infected MESH:D007239
688 37143-37160 Disease denotes PDCoV CHN-HN-1601 MESH:C535301
689 37554-37573 Disease denotes PDCoV-infected band MESH:D058745
690 36257-36264 CellLine denotes IPEC-J2 CVCL:2246
691 36293-36300 CellLine denotes IPEC-J2 CVCL:2246
692 37053-37060 CellLine denotes IPEC-J2 CVCL:2246
693 37089-37096 CellLine denotes IPEC-J2 CVCL:2246
696 39198-39207 Disease denotes infection MESH:D007239
697 39173-39180 CellLine denotes IPEC-J2 CVCL:2246
700 40846-40858 Chemical denotes carbohydrate MESH:D002241
701 41009-41014 Chemical denotes lipid MESH:D008055
704 41556-41565 Disease denotes infection MESH:D007239
705 41531-41538 CellLine denotes IPEC-J2 CVCL:2246
727 42609-42612 Gene denotes AKT Gene:207
728 42834-42838 Gene denotes mTOR Gene:2475
729 42921-42933 Gene denotes Secretagogin Gene:10590
730 42966-42970 Gene denotes AKT2 Gene:208
731 43258-43263 Gene denotes HIF-1 Gene:3091
732 43333-43336 Gene denotes AGE Gene:5973
733 42267-42272 Species denotes human Tax:9606
734 43747-43752 Species denotes human Tax:9606
735 43424-43433 Species denotes influenza Tax:11320
736 43007-43014 Chemical denotes gamma R
737 43395-43401 Chemical denotes carbon MESH:D002244
738 43504-43521 Chemical denotes glycosaminoglycan MESH:D006025
739 43536-43548 Chemical denotes progesterone MESH:D011374
740 42065-42084 Disease denotes infectious diseases MESH:D003141
741 42143-42150 Disease denotes cancers MESH:D009369
742 42657-42663 Disease denotes cancer MESH:D009369
743 43283-43299 Disease denotes HTLV-I infection MESH:D015490
744 43307-43331 Disease denotes papillomavirus infection MESH:D030361
745 43363-43385 Disease denotes diabetic complications MESH:D048909
746 43416-43422 Disease denotes cancer MESH:D009369
747 43480-43502 Disease denotes small cell lung cancer MESH:D055752
752 44180-44185 Species denotes human Tax:9606
753 43926-43935 Disease denotes infection MESH:D007239
754 44196-44198 Disease denotes HD MESH:D006816
755 43901-43908 CellLine denotes IPEC-J2 CVCL:2246
794 45352-45357 Gene denotes NUP37 Gene:79023
795 45515-45519 Gene denotes SCGN Gene:10590
796 45520-45525 Gene denotes ISG15 Gene:9636
797 45526-45530 Gene denotes OAS1 Gene:4938
798 45531-45536 Gene denotes IFIT1 Gene:3434
799 45537-45542 Gene denotes IFIT3 Gene:3437
800 45543-45549 Gene denotes ANAPC7 Gene:51434
801 45550-45554 Gene denotes NME7 Gene:29922
802 45603-45610 Gene denotes POLDIP3 Gene:84271
803 45611-45616 Gene denotes NUP37 Gene:79023
804 45617-45623 Gene denotes ERCC6L Gene:54821
805 45624-45629 Gene denotes DDX55 Gene:57696
806 45630-45637 Gene denotes SMARCA2 Gene:6595
807 45643-45648 Gene denotes BAZ2A Gene:11176
808 45649-45653 Gene denotes HLTF Gene:6596
809 45654-45660 Gene denotes CHAF1A Gene:10036
810 45661-45665 Gene denotes CDK9 Gene:1025
811 45666-45671 Gene denotes MNAT1 Gene:4331
812 45672-45677 Gene denotes CTDP1 Gene:9150
813 45678-45683 Gene denotes INTS4 Gene:92105
814 45850-45855 Gene denotes IFIT1 Gene:3434
815 45857-45862 Gene denotes IFIT3 Gene:3437
816 45864-45869 Gene denotes NUP37 Gene:79023
817 45871-45878 Gene denotes SMARCA2 Gene:6595
818 45884-45888 Gene denotes CDK9 Gene:1025
819 45905-45910 Gene denotes MNAT1 Gene:4331
820 45934-45939 Gene denotes CTDP1 Gene:9150
821 45944-45948 Gene denotes CDK9 Gene:1025
822 45954-45959 Gene denotes INTS4 Gene:92105
823 45987-45991 Gene denotes CDK9 Gene:1025
824 46118-46123 Gene denotes MEF2D Gene:4209
825 46125-46130 Gene denotes VLDLR Gene:7436
826 46143-46147 Gene denotes PDK1 Gene:5163
827 46153-46157 Gene denotes AKT2 Gene:208
828 46097-46106 Disease denotes infection MESH:D007239
829 46185-46190 Disease denotes death MESH:D003643
830 46385-46400 Disease denotes PDCoV infection MESH:D007239
831 46404-46411 CellLine denotes IPEC-J2 CVCL:2246
834 46635-46644 Disease denotes infection MESH:D007239
835 46610-46617 CellLine denotes IPEC-J2 CVCL:2246
852 48578-48581 Gene denotes NS6 Gene:4893
853 48583-48586 Gene denotes NS7 Gene:673
854 48592-48596 Gene denotes Nsp5 Gene:92521
855 48248-48252 Species denotes pigs Tax:9823
856 48017-48024 Species denotes porcine Tax:28344
857 47262-47277 Disease denotes viral infection MESH:D001102
858 47528-47544 Disease denotes viral infections MESH:D001102
859 47735-47744 Disease denotes infection MESH:D007239
860 47832-47846 Disease denotes PDCoV-infected MESH:D007239
861 47986-47995 Disease denotes infection MESH:D007239
862 48065-48080 Disease denotes PDCoV infection MESH:D007239
863 48275-48290 Disease denotes PDCoV infection MESH:D007239
864 48350-48364 Disease denotes PDCoV-infected MESH:D007239
865 47847-47854 CellLine denotes IPEC-J2 CVCL:2246
866 48109-48116 CellLine denotes IPEC-J2 CVCL:2246
867 48365-48372 CellLine denotes IPEC-J2 CVCL:2246
880 48748-48754 Gene denotes ANAPC7 Gene:51434
881 48759-48764 Gene denotes IFIT1 Gene:3434
882 48842-48848 Gene denotes ANAPC7 Gene:51434
883 49147-49153 Gene denotes ANAPC7 Gene:100155743
884 49227-49232 Gene denotes IFIT1 Gene:3434
885 49431-49436 Gene denotes IFIT1 Gene:3434
886 49337-49352 Chemical denotes 5′-triphosphate
887 49171-49182 Disease denotes dysfunction MESH:D009461
888 49210-49225 Disease denotes PDCoV infection MESH:D007239
889 49492-49506 Disease denotes PDCoV-infected MESH:D007239
890 49186-49193 CellLine denotes IPEC-J2 CVCL:2246
891 49507-49514 CellLine denotes IPEC-J2 CVCL:2246
920 50246-50251 Gene denotes ISG15 Gene:9636
921 50253-50257 Gene denotes OAS1 Gene:4938
922 50259-50262 Gene denotes Mx1 Gene:4599
923 50264-50269 Gene denotes IFIT1 Gene:3434
924 50275-50280 Gene denotes IFIT3 Gene:3437
925 50406-50412 Gene denotes ERCC6L Gene:54821
926 50414-50418 Gene denotes NME7 Gene:29922
927 50420-50424 Gene denotes NFYB Gene:4801
928 50426-50431 Gene denotes FOSL1 Gene:8061
929 50437-50442 Gene denotes CTDP1 Gene:9150
930 50586-50591 Gene denotes BAZ2A Gene:11176
931 50628-50640 Gene denotes secretagogin Gene:10590
932 50742-50747 Gene denotes VLDLR Gene:7436
933 50807-50811 Gene denotes CDK9 Gene:1025
934 50928-50933 Gene denotes FOSL1 Gene:8061
935 50935-50940 Gene denotes NUP37 Gene:79023
936 50946-50951 Gene denotes DDX55 Gene:57696
937 51455-51460 Gene denotes ISG15 Gene:9636
938 51462-51466 Gene denotes OAS1 Gene:4938
939 51468-51473 Gene denotes IFIT1 Gene:3434
940 51479-51484 Gene denotes IFIT3 Gene:3437
941 51642-51647 Gene denotes DDX55 Gene:57696
942 51649-51656 Gene denotes SMARCA2 Gene:6595
943 51662-51668 Gene denotes ERCC6L Gene:54821
944 51807-51811 Gene denotes NFYB Gene:4801
945 51813-51818 Gene denotes FOSL1 Gene:8061
946 51824-51829 Gene denotes CTDP1 Gene:9150
947 50600-50607 Chemical denotes calcium MESH:D002118
989 52659-52663 Gene denotes AKT2 Gene:208
990 52665-52670 Gene denotes IFIT1 Gene:3434
991 52672-52677 Gene denotes RSAD2 Gene:91543
992 52679-52683 Gene denotes NFYB Gene:4801
993 52685-52691 Gene denotes ANAPC7 Gene:51434
994 52693-52699 Gene denotes COL4A1 Gene:1282
995 52701-52704 Gene denotes Mx1 Gene:4599
996 52710-52715 Gene denotes ISG15 Gene:9636
997 52784-52788 Gene denotes AKT2 Gene:208
998 52790-52795 Gene denotes BNIP3 Gene:664
999 52797-52801 Gene denotes PDK1 Gene:5163
1000 52803-52808 Gene denotes WDR24 Gene:84219
1001 52810-52817 Gene denotes TMEM55B Gene:90809
1002 52823-52829 Gene denotes COL4A1 Gene:1282
1003 52893-52898 Gene denotes ISG15 Gene:9636
1004 52900-52905 Gene denotes IFIT1 Gene:3434
1005 52907-52911 Gene denotes OAS1 Gene:4938
1006 52916-52921 Gene denotes IFIT3 Gene:3437
1007 52988-52992 Gene denotes AKT2 Gene:208
1008 52994-52999 Gene denotes MT-2A Gene:4502
1009 53001-53007 Gene denotes COL4A1 Gene:1282
1010 53013-53023 Gene denotes cystatin C Gene:1471
1011 53084-53088 Gene denotes PDK1 Gene:5163
1012 53090-53094 Gene denotes AKT2 Gene:208
1013 53096-53102 Gene denotes COL4A1 Gene:1282
1014 53108-53112 Gene denotes CDK9 Gene:1025
1015 53220-53225 Gene denotes ISG15 Gene:9636
1016 53229-53234 Gene denotes IFN-α Gene:3439
1017 53411-53416 Gene denotes IFIT1 Gene:3434
1018 53429-53432 Gene denotes p56 Gene:3434
1019 53433-53438 Gene denotes ISG56 Gene:3434
1020 53798-53804 Gene denotes COL4A1 Gene:1282
1021 54175-54179 Gene denotes α-1/ Gene:597
1022 54179-54191 Gene denotes β-1 integrin Gene:3688
1023 52589-52613 Disease denotes viral infectious disease MESH:D001102
1024 53033-53039 Disease denotes cancer MESH:D009369
1025 53372-53391 Disease denotes infectious diseases MESH:D003141
1026 53727-53746 Disease denotes infectious diseases MESH:D003141
1027 53940-53958 Disease denotes infectious disease MESH:D003141
1028 54003-54010 Disease denotes cancers MESH:D009369
1029 54258-54263 Disease denotes tumor MESH:D009369
1052 54355-54358 Gene denotes AKT Gene:207
1053 54360-54364 Gene denotes mTOR Gene:2475
1054 54467-54472 Gene denotes RIG-I Gene:23586
1055 54902-54907 Gene denotes ISG15 Gene:9636
1056 54909-54913 Gene denotes OAS1 Gene:4938
1057 54915-54918 Gene denotes Mx1 Gene:4599
1058 54920-54925 Gene denotes IFIT1 Gene:3434
1059 54931-54936 Gene denotes IFIT3 Gene:3437
1060 55766-55771 Gene denotes IFN-β Gene:3439
1061 55955-55959 Gene denotes Nsp5 Gene:92521
1062 56044-56094 Gene denotes signal transducer and activator of transcription 2 Gene:6773
1063 56172-56175 Gene denotes NS6 Gene:4893
1064 56200-56205 Gene denotes IFN-β Gene:3439
1065 56269-56274 Gene denotes RIG-I Gene:23586
1066 56275-56279 Gene denotes MDA5 Gene:64135
1067 54957-54971 Disease denotes PDCoV-infected MESH:D007239
1068 55088-55104 Disease denotes viral infections MESH:D001102
1069 55181-55196 Disease denotes PDCoV infection MESH:D007239
1070 55296-55305 Disease denotes infection MESH:D007239
1071 55469-55483 Disease denotes PDCoV-infected MESH:D007239
1072 54972-54979 CellLine denotes IPEC-J2 CVCL:2246
1073 55277-55284 CellLine denotes IPEC-J2 CVCL:2246
1103 56308-56313 Gene denotes RIG-I Gene:23586
1104 56383-56386 Gene denotes AKT Gene:207
1105 56391-56395 Gene denotes mTOR Gene:2475
1106 56512-56515 Gene denotes AKT Gene:100126861
1107 56686-56689 Gene denotes AKT Gene:100126861
1108 56824-56828 Gene denotes mTOR Gene:100127359
1109 57144-57148 Gene denotes mTOR Gene:2475
1110 57158-57161 Gene denotes AKT Gene:207
1111 57352-57355 Gene denotes AKT Gene:207
1112 57356-57360 Gene denotes mTOR Gene:2475
1113 57517-57520 Gene denotes AKT Gene:207
1114 57525-57529 Gene denotes mTOR Gene:2475
1115 57711-57714 Gene denotes AKT Gene:100126861
1116 57715-57719 Gene denotes mTOR Gene:100127359
1117 58278-58281 Gene denotes AKT Gene:207
1118 58282-58286 Gene denotes mTOR Gene:2475
1119 57407-57416 Species denotes classical Tax:11096
1120 56919-56924 Chemical denotes lipid MESH:D008055
1121 56420-56434 Disease denotes PDCoV-infected MESH:D007239
1122 57029-57040 Disease denotes dysfunction MESH:D009461
1123 57108-57116 Disease denotes diabetes MESH:D003920
1124 57121-57127 Disease denotes cancer MESH:D009369
1125 57600-57614 Disease denotes PDCoV-infected MESH:D007239
1126 57776-57785 Disease denotes infection MESH:D007239
1127 57919-57928 Disease denotes infection MESH:D007239
1128 58099-58108 Disease denotes infection MESH:D007239
1129 56435-56442 CellLine denotes IPEC-J2 CVCL:2246
1130 57615-57622 CellLine denotes IPEC-J2 CVCL:2246
1131 57822-57829 CellLine denotes IPEC-J2 CVCL:2246
1163 58606-58610 Gene denotes PDK1 Gene:5163
1164 58611-58615 Gene denotes AKT2 Gene:208
1165 59055-59060 Gene denotes NUP37 Gene:79023
1166 59062-59069 Gene denotes SMARCA2 Gene:6595
1167 59075-59079 Gene denotes CDK9 Gene:100307051
1168 59165-59170 Gene denotes NUP37 Gene:79023
1169 59219-59225 Gene denotes Nup107 Gene:57122
1170 59343-59350 Gene denotes SMARCA2 Gene:6595
1171 59539-59543 Gene denotes CDK9 Gene:100307051
1172 59556-59565 Gene denotes cyclin T1 Gene:904
1173 59886-59890 Gene denotes CDK9 Gene:100307051
1174 60013-60017 Gene denotes CDK9 Gene:1025
1175 60203-60207 Gene denotes CDK9 Gene:1025
1176 60401-60405 Gene denotes CDK9 Gene:1025
1177 60553-60557 Gene denotes CDK9 Gene:1025
1178 60715-60719 Gene denotes CDK9 Gene:100307051
1179 59401-59409 Gene denotes helicase Gene:164045
1180 60103-60120 Species denotes influenza A virus Tax:11320
1181 60122-60134 Species denotes dengue virus Tax:12637
1182 60136-60152 Species denotes human adenovirus Tax:1907210
1183 60158-60186 Species denotes human immunodeficiency virus Tax:12721
1184 60278-60295 Species denotes influenza A virus Tax:11320
1185 60502-60518 Species denotes human adenovirus Tax:1907210
1186 60673-60689 Species denotes human adenovirus Tax:1907210
1187 60569-60576 Chemical denotes FIT-039 MESH:C000595272
1188 58819-58833 Disease denotes PDCoV-infected MESH:D007239
1189 59945-59951 Disease denotes cancer MESH:D009369
1190 59953-59976 Disease denotes cardiovascular diseases MESH:D002318
1191 60780-60789 Disease denotes infection MESH:D007239
1192 58834-58841 CellLine denotes IPEC-J2 CVCL:2246
1193 60755-60762 CellLine denotes IPEC-J2 CVCL:2246
1219 61317-61321 Gene denotes ErbB Gene:1956
1220 61323-61328 Gene denotes HIF-1 Gene:3091
1221 61330-61334 Gene denotes mTOR Gene:2475
1222 61340-61343 Gene denotes TNF Gene:7124
1223 61472-61475 Gene denotes Akt Gene:207
1224 61509-61513 Gene denotes mTOR Gene:2475
1225 60983-61030 Species denotes severe acute respiratory syndrome coronavirus-2 Tax:2697049
1226 61032-61042 Species denotes SARS-CoV-2 Tax:2697049
1227 61585-61595 Species denotes SARS-CoV-2 Tax:2697049
1228 62029-62039 Species denotes SARS-CoV-2 Tax:2697049
1229 62132-62142 Species denotes SARS-CoV-2 Tax:2697049
1230 61486-61493 Chemical denotes MK-2206 MESH:C548887
1231 61825-61831 Chemical denotes carbon MESH:D002244
1232 61972-61985 Chemical denotes cycloheximide MESH:D003513
1233 61990-61997 Chemical denotes emetine MESH:D004640
1234 61067-61091 Disease denotes Coronavirus Disease 2019 MESH:C000657245
1235 61093-61101 Disease denotes COVID-19 MESH:C000657245
1236 61280-61300 Disease denotes SARS-CoV-2 infection MESH:C000657245
1237 61404-61424 Disease denotes SARS-CoV-2 infection MESH:C000657245
1238 61701-61721 Disease denotes SARS-CoV-2 infection MESH:C000657245
1239 61891-61906 Disease denotes viral infection MESH:D001102
1240 62260-62279 Disease denotes SARS-CoV-2-infected MESH:C000657245
1241 61255-61259 CellLine denotes Huh7 CVCL:0336
1242 61673-61679 CellLine denotes Caco-2 CVCL:0025
1243 62146-62152 CellLine denotes Caco-2 CVCL:0025
1250 63130-63134 Gene denotes mTOR Gene:2475
1251 63141-63144 Gene denotes AKT Gene:207
1252 62642-62656 Disease denotes PDCoV-infected MESH:D007239
1253 62856-62870 Disease denotes PDCoV-infected MESH:D007239
1254 62657-62664 CellLine denotes IPEC-J2 CVCL:2246
1255 62871-62878 CellLine denotes IPEC-J2 CVCL:2246
1257 63773-63777 Chemical denotes PVDF MESH:C024865
1260 63921-63929 Disease denotes infected MESH:D007239
1261 63930-63937 CellLine denotes IPEC-J2 CVCL:2246
1264 64036-64050 Disease denotes PDCoV-infected MESH:D007239
1265 64051-64064 CellLine denotes IPEC-J2 cells CVCL:2246
1268 64848-64851 Gene denotes Xin Gene:165904
1269 64828-64831 Gene denotes Lei Gene:1992