PMC:7605337 / 59234-59458 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T80","span":{"begin":37,"end":44},"obj":"Body_part"}],"attributes":[{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma82749"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T378","span":{"begin":204,"end":213},"obj":"Disease"}],"attributes":[{"id":"A378","pred":"mondo_id","subj":"T378","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T330","span":{"begin":154,"end":155},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T45232","span":{"begin":37,"end":44},"obj":"Chemical"}],"attributes":[{"id":"A64011","pred":"chebi_id","subj":"T45232","obj":"http://purl.obolibrary.org/obo/CHEBI_16449"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T15","span":{"begin":214,"end":223},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T16","span":{"begin":214,"end":223},"obj":"http://purl.obolibrary.org/obo/GO_0009405"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}

{"project":"LitCovid-sentences","denotations":[{"id":"T392","span":{"begin":0,"end":224},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1484","span":{"begin":181,"end":185},"obj":"Gene"},{"id":"1511","span":{"begin":37,"end":44},"obj":"Chemical"},{"id":"1513","span":{"begin":204,"end":213},"obj":"Disease"}],"attributes":[{"id":"A1484","pred":"tao:has_database_id","subj":"1484","obj":"Gene:59272"},{"id":"A1511","pred":"tao:has_database_id","subj":"1511","obj":"MESH:D000409"},{"id":"A1513","pred":"tao:has_database_id","subj":"1513","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"It is also alerting that some of the alanine substitutions at residues G446, G447, and Y489 substantially increased the binding affinity that may lead to a strong RBD attachment to ACE2 and influence the infection virulence."}