PMC:7605337 / 34483-35126
Annnotations
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T225 | 80-89 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T226 | 633-642 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T223 | 95-96 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T224 | 201-204 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T225 | 205-206 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T226 | 308-309 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T227 | 463-464 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T228 | 560-563 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T229 | 564-565 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T218 | 0-112 | Sentence | denotes | Most natural mutants exhibited similar binding affinities compared to wild-type nCOV-2019 with a few exceptions. |
T219 | 113-284 | Sentence | denotes | Mutation T478I which is one of the most frequent mutations based on the GISAID database has a binding affinity which is about 6 kcal/mol higher than that of the wild-type. |
T220 | 285-369 | Sentence | denotes | S494P and A475V showed a slightly lower binding affinity than the wild-type complex. |
T221 | 370-443 | Sentence | denotes | Other natural mutants showed binding affinities similar to wild-type RBD. |
T222 | 444-643 | Sentence | denotes | N439K demonstrated a high electrostatic energy which is compensated by large polar solvation energy and this mutant has a total binding energy of −48.27 ± 3.07 kcal/mol which is similar to nCOV-2019. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
752 | 80-84 | Species | denotes | nCOV | Tax:2697049 |
753 | 633-637 | Species | denotes | nCOV | Tax:2697049 |