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PMC:7601109 / 69434-70695 JSONTXT

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LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T146 1069-1074 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T589 39-45 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T590 447-451 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T591 555-561 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T592 799-808 Body_part denotes myoblasts http://purl.org/sig/ont/fma/fma70335
T593 827-835 Body_part denotes myocytes http://purl.org/sig/ont/fma/fma67328
T594 921-927 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T595 928-935 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T596 1069-1074 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T597 1229-1235 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T121 148-158 Disease denotes sarcopenia http://purl.obolibrary.org/obo/MONDO_0006516
T122 1018-1030 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1132 30-45 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T1133 30-45 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T1134 30-45 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle
T1135 175-176 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1136 298-299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1137 367-372 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1138 447-451 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1139 464-470 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T1140 546-561 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T1141 546-561 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T1142 546-561 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle
T1143 827-835 http://purl.obolibrary.org/obo/CL_0000187 denotes myocytes
T1144 921-927 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T1145 921-927 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T1146 921-927 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T1147 921-927 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T1148 1069-1074 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1149 1069-1074 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1150 1220-1235 http://purl.obolibrary.org/obo/UBERON_0001134 denotes skeletal muscle
T1151 1220-1235 http://purl.obolibrary.org/obo/UBERON_0014892 denotes skeletal muscle
T1152 1220-1235 http://www.ebi.ac.uk/efo/EFO_0000888 denotes skeletal muscle

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T70668 123-128 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T8453 709-720 Chemical denotes royal jelly http://purl.obolibrary.org/obo/CHEBI_78665
T63197 928-935 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34326 1162-1166 Chemical denotes AGEs http://purl.obolibrary.org/obo/CHEBI_84123

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T323 928-945 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T324 936-945 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T325 1018-1030 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T326 1184-1194 http://purl.obolibrary.org/obo/GO_0009056 denotes catabolism
T327 1220-1243 http://purl.obolibrary.org/obo/GO_0014732 denotes skeletal muscle atrophy
T328 1229-1243 http://purl.obolibrary.org/obo/GO_0014889 denotes muscle atrophy

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T70 979-995 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T71 1220-1243 Phenotype denotes skeletal muscle atrophy http://purl.obolibrary.org/obo/HP_0003202

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T417 0-159 Sentence denotes Age-related deteriorations in skeletal muscle are multifactorial in nature, which contributes to the high failure rates of drugs designed to target sarcopenia.
T418 160-344 Sentence denotes Thus, there is a strong need for new therapeutic agents that express multidimensional effects in order to provide physically frail elders a chance to restore their health and QoL [21].
T419 345-618 Sentence denotes Given the scarcity of human trials using bee products among physically frail and sarcopenic subjects, cell culture and animal studies may provide useful information about the effect of bee products on skeletal muscle and help identifying their probable mechanism of action.
T420 619-836 Sentence denotes Both in vivo and in vitro studies indicate that substances produced by honey bees such as royal jelly, bee pollen, and propolis can positively modulate basic cellular functions of myoblasts as well as mature myocytes.
T421 837-1261 Sentence denotes These products seem to be promising anti-sarcopenic agents because they can promote muscle protein synthesis [36,104], decrease mitochondrial oxidative stress [36,90,106], mitigate inflammation [38,90,101,108,115], improve muscular blood supply [102,110], enhance peripheral motor conduction [113], accelerate the removal of AGEs [38], counteract catabolism, and decrease markers of skeletal muscle atrophy [97,101,102,103].

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1590 0-3 Gene denotes Age Gene:81759
1591 367-372 Species denotes human Tax:9606
1592 690-700 Species denotes honey bees Tax:7460
1593 148-158 Disease denotes sarcopenia MESH:D055948
1594 1018-1030 Disease denotes inflammation MESH:D007249
1595 1220-1243 Disease denotes skeletal muscle atrophy MESH:D009133