PMC:7601109 / 65133-65485
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T543 | 42-46 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T544 | 108-115 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1045 | 42-46 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T1046 | 73-83 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T1047 | 98-107 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
| T1048 | 258-259 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T17126 | 108-115 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T313 | 42-59 | http://purl.obolibrary.org/obo/GO_0007050 | denotes | cell-cycle arrest |
| T314 | 124-128 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | MAPK |
| T315 | 279-302 | http://purl.obolibrary.org/obo/GO_1903009 | denotes | proteasomal degradation |
| T316 | 291-302 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T68 | 173-180 | Phenotype | denotes | hypoxia | http://purl.obolibrary.org/obo/HP_0012418 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T388 | 0-352 | Sentence | denotes | The molecular mechanism involved inducing cell-cycle arrest in VSMCs via activation of p38mitogen-activated protein kinase (MAPK), which was associated with accumulation of hypoxia-inducible factor (HIF)-1α—mainly due to inhibition of HIF prolylhydroxylase, a key contributor to proteasomal degradation of HIF-1α—and subsequent induction of HO-1 [155]. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1530 | 87-122 | Gene | denotes | p38mitogen-activated protein kinase | Gene:81649 |
| 1531 | 173-206 | Gene | denotes | hypoxia-inducible factor (HIF)-1α | Gene:29560 |
| 1532 | 306-312 | Gene | denotes | HIF-1α | Gene:29560 |
| 1533 | 341-345 | Gene | denotes | HO-1 | Gene:24451 |
| 1550 | 53-59 | Disease | denotes | arrest | MESH:D006323 |