PMC:7601109 / 38352-38578 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T233","span":{"begin":187,"end":194},"obj":"Body_part"}],"attributes":[{"id":"A233","pred":"fma_id","subj":"T233","obj":"http://purl.org/sig/ont/fma/fma9637"}],"text":"PGC-1α functions as a key regulator of sirtuin 1, which limits ROS production through stimulation of mitochondrial biogenesis and ROS defense system, thus protecting metabolically active tissues against oxidative damage [120]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T493","span":{"begin":20,"end":21},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T494","span":{"begin":180,"end":186},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"PGC-1α functions as a key regulator of sirtuin 1, which limits ROS production through stimulation of mitochondrial biogenesis and ROS defense system, thus protecting metabolically active tissues against oxidative damage [120]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T551","span":{"begin":0,"end":3},"obj":"Chemical"},{"id":"T552","span":{"begin":63,"end":66},"obj":"Chemical"},{"id":"T553","span":{"begin":130,"end":133},"obj":"Chemical"}],"attributes":[{"id":"A551","pred":"chebi_id","subj":"T551","obj":"http://purl.obolibrary.org/obo/CHEBI_26336"},{"id":"A552","pred":"chebi_id","subj":"T552","obj":"http://purl.obolibrary.org/obo/CHEBI_26523"},{"id":"A553","pred":"chebi_id","subj":"T553","obj":"http://purl.obolibrary.org/obo/CHEBI_26523"}],"text":"PGC-1α functions as a key regulator of sirtuin 1, which limits ROS production through stimulation of mitochondrial biogenesis and ROS defense system, thus protecting metabolically active tissues against oxidative damage [120]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T240","span":{"begin":0,"end":226},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"PGC-1α functions as a key regulator of sirtuin 1, which limits ROS production through stimulation of mitochondrial biogenesis and ROS defense system, thus protecting metabolically active tissues against oxidative damage [120]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"834","span":{"begin":0,"end":6},"obj":"Gene"},{"id":"835","span":{"begin":39,"end":48},"obj":"Gene"},{"id":"847","span":{"begin":63,"end":66},"obj":"Chemical"},{"id":"848","span":{"begin":130,"end":133},"obj":"Chemical"}],"attributes":[{"id":"A834","pred":"tao:has_database_id","subj":"834","obj":"Gene:19017"},{"id":"A835","pred":"tao:has_database_id","subj":"835","obj":"Gene:309757"},{"id":"A847","pred":"tao:has_database_id","subj":"847","obj":"MESH:D017382"},{"id":"A848","pred":"tao:has_database_id","subj":"848","obj":"MESH:D017382"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"PGC-1α functions as a key regulator of sirtuin 1, which limits ROS production through stimulation of mitochondrial biogenesis and ROS defense system, thus protecting metabolically active tissues against oxidative damage [120]."}