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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7601109","sourcedb":"PMC","sourceid":"7601109","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7601109","text":"Dry pollen pellets resist decay due to their tough outer coat, which comprises two layers made of cellulose and sporopollenin [88,89]. However, ingestion of bee pollen by humans may not yield its optimal nutritional value because the hard sporopollenin shell hinders access of digestive secretions to the nutrient-rich core of the pellet. Biological, chemical, and mechanical techniques are used to break bee pollen microcapsules in order to enhance its digestibility in the gut. However, these methods may be expensive or ineffective i.e., they degrade important nutrients via enzymatic activity [88,90]. Ultraviolet spectroscopy and high performance liquid chromatography-photo diode array show that processing bee pollen through the use of an edible lipid-surfactant mixture (Captex 355 and Tween 80) increases its yield of polyphenols and flavonoid aglycones 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