PMC:7601109 / 15107-16729 JSON TXT

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LitCovid-PD-FMA-UBERON

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T99561","span":{"begin":1556,"end":1567},"obj":"Body_part"}],"attributes":[{"id":"A57253","pred":"fma_id","subj":"T99561","obj":"http://purl.org/sig/ont/fma/fma82738"}],"text":"Propolis is a unique product of a complex composition that comprises more than 420 chemical substances [37,68]. Nonetheless, its composition and biological activities vary considerably depending on its botanical and geographical origins as well as the time of harvesting [38,65,67]. Propolis is rich in oxyprenylated phenylpropanoids—secondary metabolites from plants, fungi, and bacteria [69]—such as 7-isopentenyloxucoumarin, boropinic acid, 4-geranyloxyferulic acid, and auraptene. The last two exist in raw Italian propolis at high concentrations: 107.12 and 145.37 μg/g of dry propolis, respectively. Flavonoids, a large group of phenolic compounds, are abundant in Italian propolis, and they are differentiated into several groups including flavanones (e.g., naringenine, 4.4 mg/g), flavones (e.g., apigenine, 1.7 mg/g), flavonols (e.g., galaning, 0.9 mg/g), tannins (e.g., gallic acid 8.4 mg/g), catechins (expressed as (+)-catechin 0.4 mg/g, and caffeic acid and its esters (expressed as caffeic acid, 9.2 mg/g) [69]. The most profuse flavonoids in ethanolic extracts of Brazilian propolis are artepillin C (38.6 mg/g), coumaric acid (10.6 mg/g), and kaempferide (12.6 mg/g) [70]. Key other constituents of propolis include polyphenol (e.g., phenolic acids and aromatic esters), phenolic aldehydes, terpenoids, ketones, enzymes (e.g., α- and β-amylase), vitamins (e.g., thiamin (B1), riboflavin (B2), pyridoxine (B6), ascorbic acid (C), tocopherol (E)), minerals (e.g., calcium, potassium, magnesium, iron, sodium, barium) essential oils, alcohol, fatty acids, β-steroids, and many other elements [37,38,67,68,71]."}

LitCovid-PD-CLO

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T38854","span":{"begin":12,"end":13},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T71056","span":{"begin":32,"end":33},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T1706","span":{"begin":156,"end":166},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T26250","span":{"begin":380,"end":388},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_2"},{"id":"T30979","span":{"begin":571,"end":574},"obj":"http://purl.obolibrary.org/obo/CLO_0003417"},{"id":"T46507","span":{"begin":618,"end":619},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Propolis is a unique product of a complex composition that comprises more than 420 chemical substances [37,68]. Nonetheless, its composition and biological activities vary considerably depending on its botanical and geographical origins as well as the time of harvesting [38,65,67]. Propolis is rich in oxyprenylated phenylpropanoids—secondary metabolites from plants, fungi, and bacteria [69]—such as 7-isopentenyloxucoumarin, boropinic acid, 4-geranyloxyferulic acid, and auraptene. The last two exist in raw Italian propolis at high concentrations: 107.12 and 145.37 μg/g of dry propolis, respectively. Flavonoids, a large group of phenolic compounds, are abundant in Italian propolis, and they are differentiated into several groups including flavanones (e.g., naringenine, 4.4 mg/g), flavones (e.g., apigenine, 1.7 mg/g), flavonols (e.g., galaning, 0.9 mg/g), tannins (e.g., gallic acid 8.4 mg/g), catechins (expressed as (+)-catechin 0.4 mg/g, and caffeic acid and its esters (expressed as caffeic acid, 9.2 mg/g) [69]. The most profuse flavonoids in ethanolic extracts of Brazilian propolis are artepillin C (38.6 mg/g), coumaric acid (10.6 mg/g), and kaempferide (12.6 mg/g) [70]. Key other constituents of propolis include polyphenol (e.g., phenolic acids and aromatic esters), phenolic aldehydes, terpenoids, ketones, enzymes (e.g., α- and β-amylase), vitamins (e.g., thiamin (B1), riboflavin (B2), pyridoxine (B6), ascorbic acid (C), tocopherol (E)), minerals (e.g., calcium, potassium, magnesium, iron, sodium, barium) essential oils, alcohol, fatty acids, β-steroids, and many other elements [37,38,67,68,71]."}

LitCovid-PD-CHEBI

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T95","span":{"begin":0,"end":111},"obj":"Sentence"},{"id":"T96","span":{"begin":112,"end":282},"obj":"Sentence"},{"id":"T97","span":{"begin":283,"end":484},"obj":"Sentence"},{"id":"T98","span":{"begin":485,"end":551},"obj":"Sentence"},{"id":"T99","span":{"begin":552,"end":605},"obj":"Sentence"},{"id":"T100","span":{"begin":606,"end":1025},"obj":"Sentence"},{"id":"T101","span":{"begin":1026,"end":1188},"obj":"Sentence"},{"id":"T102","span":{"begin":1189,"end":1622},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Propolis is a unique product of a complex composition that comprises more than 420 chemical substances [37,68]. Nonetheless, its composition and biological activities vary considerably depending on its botanical and geographical origins as well as the time of harvesting [38,65,67]. Propolis is rich in oxyprenylated phenylpropanoids—secondary metabolites from plants, fungi, and bacteria [69]—such as 7-isopentenyloxucoumarin, boropinic acid, 4-geranyloxyferulic acid, and auraptene. The last two exist in raw Italian propolis at high concentrations: 107.12 and 145.37 μg/g of dry propolis, respectively. Flavonoids, a large group of phenolic compounds, are abundant in Italian propolis, and they are differentiated into several groups including flavanones (e.g., naringenine, 4.4 mg/g), flavones (e.g., apigenine, 1.7 mg/g), flavonols (e.g., galaning, 0.9 mg/g), tannins (e.g., gallic acid 8.4 mg/g), catechins (expressed as (+)-catechin 0.4 mg/g, and caffeic acid and its esters (expressed as caffeic acid, 9.2 mg/g) [69]. The most profuse flavonoids in ethanolic extracts of Brazilian propolis are artepillin C (38.6 mg/g), coumaric acid (10.6 mg/g), and kaempferide (12.6 mg/g) [70]. Key other constituents of propolis include polyphenol (e.g., phenolic acids and aromatic esters), phenolic aldehydes, terpenoids, ketones, enzymes (e.g., α- and β-amylase), vitamins (e.g., thiamin (B1), riboflavin (B2), pyridoxine (B6), ascorbic acid (C), tocopherol (E)), minerals (e.g., calcium, potassium, magnesium, iron, sodium, barium) essential oils, alcohol, fatty acids, β-steroids, and many other elements [37,38,67,68,71]."}

LitCovid-PubTator

{"project":"LitCovid-PubTator","denotations":[{"id":"285","span":{"begin":317,"end":333},"obj":"Chemical"},{"id":"286","span":{"begin":402,"end":426},"obj":"Chemical"},{"id":"287","span":{"begin":428,"end":442},"obj":"Chemical"},{"id":"288","span":{"begin":444,"end":468},"obj":"Chemical"},{"id":"289","span":{"begin":474,"end":483},"obj":"Chemical"},{"id":"290","span":{"begin":1043,"end":1053},"obj":"Chemical"},{"id":"291","span":{"begin":1102,"end":1114},"obj":"Chemical"},{"id":"292","span":{"begin":1128,"end":1141},"obj":"Chemical"},{"id":"293","span":{"begin":1159,"end":1170},"obj":"Chemical"}],"attributes":[{"id":"A288","pred":"tao:has_database_id","subj":"288","obj":"MESH:C552732"},{"id":"A289","pred":"tao:has_database_id","subj":"289","obj":"MESH:C105832"},{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"MESH:D005419"},{"id":"A291","pred":"tao:has_database_id","subj":"291","obj":"MESH:C102259"},{"id":"A292","pred":"tao:has_database_id","subj":"292","obj":"MESH:D003373"},{"id":"A293","pred":"tao:has_database_id","subj":"293","obj":"MESH:C449720"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Propolis is a unique product of a complex composition that comprises more than 420 chemical substances [37,68]. Nonetheless, its composition and biological activities vary considerably depending on its botanical and geographical origins as well as the time of harvesting [38,65,67]. Propolis is rich in oxyprenylated phenylpropanoids—secondary metabolites from plants, fungi, and bacteria [69]—such as 7-isopentenyloxucoumarin, boropinic acid, 4-geranyloxyferulic acid, and auraptene. The last two exist in raw Italian propolis at high concentrations: 107.12 and 145.37 μg/g of dry propolis, respectively. Flavonoids, a large group of phenolic compounds, are abundant in Italian propolis, and they are differentiated into several groups including flavanones (e.g., naringenine, 4.4 mg/g), flavones (e.g., apigenine, 1.7 mg/g), flavonols (e.g., galaning, 0.9 mg/g), tannins (e.g., gallic acid 8.4 mg/g), catechins (expressed as (+)-catechin 0.4 mg/g, and caffeic acid and its esters (expressed as caffeic acid, 9.2 mg/g) [69]. The most profuse flavonoids in ethanolic extracts of Brazilian propolis are artepillin C (38.6 mg/g), coumaric acid (10.6 mg/g), and kaempferide (12.6 mg/g) [70]. Key other constituents of propolis include polyphenol (e.g., phenolic acids and aromatic esters), phenolic aldehydes, terpenoids, ketones, enzymes (e.g., α- and β-amylase), vitamins (e.g., thiamin (B1), riboflavin (B2), pyridoxine (B6), ascorbic acid (C), tocopherol (E)), minerals (e.g., calcium, potassium, magnesium, iron, sodium, barium) essential oils, alcohol, fatty acids, β-steroids, and many other elements [37,38,67,68,71]."}