PMC:7600245 / 95443-96677
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T431 | 109-117 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T432 | 287-298 | Body_part | denotes | microtubule | http://purl.org/sig/ont/fma/fma63849 |
| T433 | 386-390 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T434 | 497-501 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T435 | 543-571 | Body_part | denotes | polymorphonuclear leukocytes | http://purl.org/sig/ont/fma/fma62860 |
| T436 | 694-702 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T437 | 848-858 | Body_part | denotes | neutrophil | http://purl.org/sig/ont/fma/fma62860 |
| T438 | 946-955 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
| T439 | 1069-1077 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T440 | 1082-1085 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T441 | 1148-1156 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T442 | 1210-1218 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T443 | 1225-1229 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T48 | 946-955 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T435 | 848-868 | Disease | denotes | neutrophil migration | http://purl.obolibrary.org/obo/MONDO_0008091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T953 | 64-65 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
| T954 | 88-97 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Humanized |
| T955 | 143-145 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T956 | 367-372 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T957 | 497-501 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T958 | 677-682 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T959 | 755-761 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | Active |
| T960 | 1052-1057 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T961 | 1193-1198 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T699 | 119-121 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T32906 | 158-164 | Chemical | denotes | Jakafi | http://purl.obolibrary.org/obo/CHEBI_66917 |
| T29671 | 173-181 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T11714 | 195-204 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T704 | 210-220 | Chemical | denotes | Colchicine | http://purl.obolibrary.org/obo/CHEBI_27882 |
| T65432 | 237-245 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T8416 | 373-384 | Chemical | denotes | polypeptide | http://purl.obolibrary.org/obo/CHEBI_15841 |
| T53143 | 386-388 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T51068 | 400-410 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T84855 | 455-463 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T711 | 620-628 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T50772 | 642-651 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T713 | 704-706 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T24627 | 731-744 | Chemical | denotes | Dexamethasone | http://purl.obolibrary.org/obo/CHEBI_41879 |
| T716 | 745-753 | Chemical | denotes | Decadron | http://purl.obolibrary.org/obo/CHEBI_41879 |
| T717 | 782-790 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T718 | 807-821 | Chemical | denotes | glucocorticoid | http://purl.obolibrary.org/obo/CHEBI_24261 |
| T719 | 974-983 | Chemical | denotes | Sirolimus | http://purl.obolibrary.org/obo/CHEBI_9168 |
| T720 | 984-992 | Chemical | denotes | Rapamune | http://purl.obolibrary.org/obo/CHEBI_9168 |
| T721 | 1001-1009 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T722 | 1016-1033 | Chemical | denotes | pathway inhibitor | http://purl.obolibrary.org/obo/CHEBI_76932 |
| T723 | 1024-1033 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T724 | 1079-1081 | Chemical | denotes | GM | http://purl.obolibrary.org/obo/CHEBI_74120 |
| T725 | 1163-1165 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T727 | 1225-1227 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T191 | 287-313 | http://purl.obolibrary.org/obo/GO_0046785 | denotes | microtubule polymerization |
| T192 | 497-512 | http://purl.obolibrary.org/obo/GO_0010467 | denotes | gene expression |
| T193 | 848-868 | http://purl.obolibrary.org/obo/GO_1990266 | denotes | neutrophil migration |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T107 | 936-968 | Phenotype | denotes | increased capillary permeability | http://purl.obolibrary.org/obo/HP_0030005 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T787 | 0-65 | Sentence | denotes | Therapy Type Mechanism No. of Interventional Clinical Trials b |
| T788 | 66-145 | Sentence | denotes | Tocilizumab(Actemra) Humanized monoclonal antibody IL-6 receptor blocker ~41 |
| T789 | 146-209 | Sentence | denotes | Ruxolitinib(Jakafi) Small molecule JAK 1 and 2 inhibitor ~15 |
| T790 | 210-318 | Sentence | denotes | Colchicine(Colcrys) Small molecule Inhibition of NLRP3 inflammasome and of microtubule polymerization ~15 |
| T791 | 319-415 | Sentence | denotes | Anakinra(Kineret) Recombinant non-glycosylated human polypeptide IL-1 receptor antagonist ~13 |
| T792 | 416-590 | Sentence | denotes | Methylprednisolone (DEPOMedrol) Small molecule Intracellular receptor-mediated gene expression & suppression of migration of polymorphonuclear leukocytes, among others ~13 |
| T793 | 591-656 | Sentence | denotes | Baricitinib(Olumiant) Small molecule JAK 1 and 2 inhibitor ~12 |
| T794 | 657-730 | Sentence | denotes | Sarilumab(Kevzara) Human monoclonal antibody IL-6 receptor blocker ~10 |
| T795 | 731-973 | Sentence | denotes | Dexamethasone(Decadron, Active Injection D) Small molecule Stimulation of glucocorticoid receptors, suppression of neutrophil migration, suppression of inflammatory mediators production, and reversal of increased capillary permeability ~10 |
| T796 | 974-1037 | Sentence | denotes | Sirolimus(Rapamune) Small molecule mTOR pathway inhibitor ~4 |
| T797 | 1038-1106 | Sentence | denotes | Mavrilimumab Human monoclonal antibody GM-CSF receptor blocker ~4 |
| T798 | 1107-1171 | Sentence | denotes | Siltuximab(Sylvant) Chimeric monoclonal antibody Anti-IL-6 ~2 |
| T799 | 1172-1234 | Sentence | denotes | Canakinumab(Ilaris) Human monoclonal antibody Anti-IL-1β ~2 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 4070 | 183-194 | Gene | denotes | JAK 1 and 2 | Gene:3716 |
| 4071 | 261-266 | Gene | denotes | NLRP3 | Gene:114548 |
| 4072 | 630-641 | Gene | denotes | JAK 1 and 2 | Gene:3716 |
| 4073 | 1011-1015 | Gene | denotes | mTOR | Gene:2475 |
| 4074 | 1163-1167 | Gene | denotes | IL-6 | Gene:3569 |
| 4075 | 1225-1230 | Gene | denotes | IL-1β | Gene:3552 |
| 4076 | 367-372 | Species | denotes | human | Tax:9606 |
| 4077 | 677-682 | Species | denotes | Human | Tax:9606 |
| 4078 | 1052-1057 | Species | denotes | Human | Tax:9606 |
| 4079 | 1193-1198 | Species | denotes | Human | Tax:9606 |
| 4080 | 704-708 | Gene | denotes | IL-6 | Gene:3569 |
| 4081 | 119-123 | Gene | denotes | IL-6 | Gene:3569 |
| 4082 | 66-77 | Chemical | denotes | Tocilizumab | MESH:C502936 |
| 4083 | 78-85 | Chemical | denotes | Actemra | MESH:C502936 |
| 4084 | 146-157 | Chemical | denotes | Ruxolitinib | MESH:C540383 |
| 4085 | 210-220 | Chemical | denotes | Colchicine | MESH:D003078 |