PMC:7600245 / 92182-92845
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T428 | 360-363 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T425 | 204-212 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T927 | 1-2 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T928 | 237-247 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T929 | 308-309 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T930 | 335-343 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T931 | 364-371 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T932 | 439-440 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T933 | 446-452 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T934 | 637-638 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T2652 | 40-55 | Chemical | denotes | isopropyl ester | http://purl.obolibrary.org/obo/CHEBI_35725 |
T62664 | 40-49 | Chemical | denotes | isopropyl | http://purl.obolibrary.org/obo/CHEBI_30353 |
T54132 | 50-55 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
T82782 | 56-63 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
T19524 | 67-81 | Chemical | denotes | ribonucleoside | http://purl.obolibrary.org/obo/CHEBI_18254 |
T607 | 152-162 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T15387 | 325-334 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T22024 | 426-436 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
T30933 | 483-488 | Chemical | denotes | oxime | http://purl.obolibrary.org/obo/CHEBI_25750 |
T38286 | 507-514 | Chemical | denotes | uridine | http://purl.obolibrary.org/obo/CHEBI_16704 |
T50020 | 530-539 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
T71234 | 573-581 | Chemical | denotes | cytidine | http://purl.obolibrary.org/obo/CHEBI_17562 |
T55928 | 597-606 | Chemical | denotes | guanosine | http://purl.obolibrary.org/obo/CHEBI_16750 |
T64872 | 612-616 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T745 | 116-215 | Sentence | denotes | EIDD-2801 is an orally bioavailable nucleoside derivative that is under development for SARS-CoV-2. |
T746 | 216-607 | Sentence | denotes | Also depicted is its activation to the corresponding tri-phosphorylated form which exhibits a broad-spectrum antiviral activity against various RNA viruses, including coronaviruses with resistance mutations to remdesivir. (B) The active form exists in two forms: the oxime form which mimics uridine and pairs with adenosine, while the other tautomer mimics cytidine and pairs with guanosine. |
T747 | 608-663 | Sentence | denotes | The drug eventually leads to a viral error catastrophe. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
3983 | 204-214 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
3984 | 383-396 | Species | denotes | coronaviruses | Tax:11118 |
3985 | 40-55 | Chemical | denotes | isopropyl ester | |
3986 | 67-81 | Chemical | denotes | ribonucleoside | MESH:D012263 |
3987 | 92-114 | Chemical | denotes | β-D-N4-hydroxycytidine | MESH:C010737 |
3988 | 152-162 | Chemical | denotes | nucleoside | MESH:D009705 |
3989 | 426-436 | Chemical | denotes | remdesivir | MESH:C000606551 |
3990 | 483-488 | Chemical | denotes | oxime | MESH:D010091 |
3991 | 507-514 | Chemical | denotes | uridine | MESH:D014529 |
3992 | 530-539 | Chemical | denotes | adenosine | MESH:D000241 |
3993 | 573-581 | Chemical | denotes | cytidine | MESH:D003562 |
3994 | 597-606 | Chemical | denotes | guanosine | MESH:D006151 |
3995 | 639-662 | Disease | denotes | viral error catastrophe |