PMC:7600245 / 92172-92845
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T428 | 370-373 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T425 | 214-222 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T927 | 11-12 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T928 | 247-257 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T929 | 318-319 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T930 | 345-353 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T931 | 374-381 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T932 | 449-450 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T933 | 456-462 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T934 | 647-648 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T2652 | 50-65 | Chemical | denotes | isopropyl ester | http://purl.obolibrary.org/obo/CHEBI_35725 |
| T62664 | 50-59 | Chemical | denotes | isopropyl | http://purl.obolibrary.org/obo/CHEBI_30353 |
| T54132 | 60-65 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T82782 | 66-73 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
| T19524 | 77-91 | Chemical | denotes | ribonucleoside | http://purl.obolibrary.org/obo/CHEBI_18254 |
| T607 | 162-172 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T15387 | 335-344 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T22024 | 436-446 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T30933 | 493-498 | Chemical | denotes | oxime | http://purl.obolibrary.org/obo/CHEBI_25750 |
| T38286 | 517-524 | Chemical | denotes | uridine | http://purl.obolibrary.org/obo/CHEBI_16704 |
| T50020 | 540-549 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T71234 | 583-591 | Chemical | denotes | cytidine | http://purl.obolibrary.org/obo/CHEBI_17562 |
| T55928 | 607-616 | Chemical | denotes | guanosine | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T64872 | 622-626 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T744 | 0-125 | Sentence | denotes | Figure 5 (A) Chemical structure of EIDD-2801, an isopropyl ester prodrug of ribonucleoside analog of β-D-N4-hydroxycytidine. |
| T745 | 126-225 | Sentence | denotes | EIDD-2801 is an orally bioavailable nucleoside derivative that is under development for SARS-CoV-2. |
| T746 | 226-617 | Sentence | denotes | Also depicted is its activation to the corresponding tri-phosphorylated form which exhibits a broad-spectrum antiviral activity against various RNA viruses, including coronaviruses with resistance mutations to remdesivir. (B) The active form exists in two forms: the oxime form which mimics uridine and pairs with adenosine, while the other tautomer mimics cytidine and pairs with guanosine. |
| T747 | 618-673 | Sentence | denotes | The drug eventually leads to a viral error catastrophe. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 3983 | 214-224 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 3984 | 393-406 | Species | denotes | coronaviruses | Tax:11118 |
| 3985 | 50-65 | Chemical | denotes | isopropyl ester | |
| 3986 | 77-91 | Chemical | denotes | ribonucleoside | MESH:D012263 |
| 3987 | 102-124 | Chemical | denotes | β-D-N4-hydroxycytidine | MESH:C010737 |
| 3988 | 162-172 | Chemical | denotes | nucleoside | MESH:D009705 |
| 3989 | 436-446 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 3990 | 493-498 | Chemical | denotes | oxime | MESH:D010091 |
| 3991 | 517-524 | Chemical | denotes | uridine | MESH:D014529 |
| 3992 | 540-549 | Chemical | denotes | adenosine | MESH:D000241 |
| 3993 | 583-591 | Chemical | denotes | cytidine | MESH:D003562 |
| 3994 | 607-616 | Chemical | denotes | guanosine | MESH:D006151 |
| 3995 | 649-672 | Disease | denotes | viral error catastrophe |