PMC:7600245 / 69202-69972 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T325","span":{"begin":248,"end":256},"obj":"Disease"},{"id":"T326","span":{"begin":611,"end":620},"obj":"Disease"},{"id":"T327","span":{"begin":662,"end":670},"obj":"Disease"},{"id":"T328","span":{"begin":713,"end":734},"obj":"Disease"},{"id":"T329","span":{"begin":739,"end":763},"obj":"Disease"}],"attributes":[{"id":"A325","pred":"mondo_id","subj":"T325","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A326","pred":"mondo_id","subj":"T326","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A327","pred":"mondo_id","subj":"T327","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A328","pred":"mondo_id","subj":"T328","obj":"http://purl.obolibrary.org/obo/MONDO_0030602"},{"id":"A329","pred":"mondo_id","subj":"T329","obj":"http://purl.obolibrary.org/obo/MONDO_0005972"}],"text":"Povidone-iodine is a chemical complex of polyvinylpyrrolidone polymer and iodine (PVP-I). It is being tested in the U.S., France, United Kingdom, Singapore, and Malaysia as a gargle, mouthwash, or nasal spray to reduce nasopharyngeal viral load in COVID-19 patients. Reports have highlighted the virucidal effect of diluted PVP-I concentration (\u003c10%), without toxic effects on respiratory cilia, olfactory function, or mucosal appearance [250]. In this direction, in vitro studies of 0.23% PVP-I mouthwash suggested that, following a 15-s exposure, the solution can provide effective antiviral activity against influenza virus A (H1N1), MERS-CoV, rotavirus, and SARS-CoV as well as antibacterial activity against Klebsiella pneumoniae and Streptococcus pneumoniae [251]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T706","span":{"begin":19,"end":20},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T707","span":{"begin":102,"end":108},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T708","span":{"begin":173,"end":174},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T709","span":{"begin":532,"end":536},"obj":"http://purl.obolibrary.org/obo/CLO_0001557"},{"id":"T710","span":{"begin":594,"end":602},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T711","span":{"begin":621,"end":626},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T712","span":{"begin":627,"end":628},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T713","span":{"begin":696,"end":704},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Povidone-iodine is a chemical complex of polyvinylpyrrolidone polymer and iodine (PVP-I). It is being tested in the U.S., France, United Kingdom, Singapore, and Malaysia as a gargle, mouthwash, or nasal spray to reduce nasopharyngeal viral load in COVID-19 patients. Reports have highlighted the virucidal effect of diluted PVP-I concentration (\u003c10%), without toxic effects on respiratory cilia, olfactory function, or mucosal appearance [250]. In this direction, in vitro studies of 0.23% PVP-I mouthwash suggested that, following a 15-s exposure, the solution can provide effective antiviral activity against influenza virus A (H1N1), MERS-CoV, rotavirus, and SARS-CoV as well as antibacterial activity against Klebsiella pneumoniae and Streptococcus pneumoniae [251]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T70344","span":{"begin":0,"end":15},"obj":"Chemical"},{"id":"T9954","span":{"begin":0,"end":8},"obj":"Chemical"},{"id":"T7506","span":{"begin":9,"end":15},"obj":"Chemical"},{"id":"T33917","span":{"begin":41,"end":61},"obj":"Chemical"},{"id":"T96460","span":{"begin":62,"end":69},"obj":"Chemical"},{"id":"T48380","span":{"begin":74,"end":80},"obj":"Chemical"},{"id":"T35605","span":{"begin":82,"end":85},"obj":"Chemical"},{"id":"T244","span":{"begin":324,"end":327},"obj":"Chemical"},{"id":"T72509","span":{"begin":490,"end":493},"obj":"Chemical"},{"id":"T248","span":{"begin":553,"end":561},"obj":"Chemical"},{"id":"T82503","span":{"begin":584,"end":593},"obj":"Chemical"}],"attributes":[{"id":"A63237","pred":"chebi_id","subj":"T70344","obj":"http://purl.obolibrary.org/obo/CHEBI_8347"},{"id":"A56074","pred":"chebi_id","subj":"T9954","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A74908","pred":"chebi_id","subj":"T7506","obj":"http://purl.obolibrary.org/obo/CHEBI_24859"},{"id":"A86838","pred":"chebi_id","subj":"T33917","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A65036","pred":"chebi_id","subj":"T96460","obj":"http://purl.obolibrary.org/obo/CHEBI_33839"},{"id":"A47704","pred":"chebi_id","subj":"T96460","obj":"http://purl.obolibrary.org/obo/CHEBI_60027"},{"id":"A19203","pred":"chebi_id","subj":"T48380","obj":"http://purl.obolibrary.org/obo/CHEBI_24859"},{"id":"A54664","pred":"chebi_id","subj":"T35605","obj":"http://purl.obolibrary.org/obo/CHEBI_53245"},{"id":"A26915","pred":"chebi_id","subj":"T35605","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A15163","pred":"chebi_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/CHEBI_53245"},{"id":"A53176","pred":"chebi_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A15272","pred":"chebi_id","subj":"T72509","obj":"http://purl.obolibrary.org/obo/CHEBI_53245"},{"id":"A81026","pred":"chebi_id","subj":"T72509","obj":"http://purl.obolibrary.org/obo/CHEBI_53248"},{"id":"A58849","pred":"chebi_id","subj":"T248","obj":"http://purl.obolibrary.org/obo/CHEBI_75958"},{"id":"A25971","pred":"chebi_id","subj":"T82503","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"Povidone-iodine is a chemical complex of polyvinylpyrrolidone polymer and iodine (PVP-I). It is being tested in the U.S., France, United Kingdom, Singapore, and Malaysia as a gargle, mouthwash, or nasal spray to reduce nasopharyngeal viral load in COVID-19 patients. Reports have highlighted the virucidal effect of diluted PVP-I concentration (\u003c10%), without toxic effects on respiratory cilia, olfactory function, or mucosal appearance [250]. In this direction, in vitro studies of 0.23% PVP-I mouthwash suggested that, following a 15-s exposure, the solution can provide effective antiviral activity against influenza virus A (H1N1), MERS-CoV, rotavirus, and SARS-CoV as well as antibacterial activity against Klebsiella pneumoniae and Streptococcus pneumoniae [251]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T86","span":{"begin":724,"end":734},"obj":"Phenotype"},{"id":"T87","span":{"begin":753,"end":763},"obj":"Phenotype"}],"attributes":[{"id":"A86","pred":"hp_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A87","pred":"hp_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"Povidone-iodine is a chemical complex of polyvinylpyrrolidone polymer and iodine (PVP-I). It is being tested in the U.S., France, United Kingdom, Singapore, and Malaysia as a gargle, mouthwash, or nasal spray to reduce nasopharyngeal viral load in COVID-19 patients. Reports have highlighted the virucidal effect of diluted PVP-I concentration (\u003c10%), without toxic effects on respiratory cilia, olfactory function, or mucosal appearance [250]. In this direction, in vitro studies of 0.23% PVP-I mouthwash suggested that, following a 15-s exposure, the solution can provide effective antiviral activity against influenza virus A (H1N1), MERS-CoV, rotavirus, and SARS-CoV as well as antibacterial activity against Klebsiella pneumoniae and Streptococcus pneumoniae [251]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T540","span":{"begin":0,"end":89},"obj":"Sentence"},{"id":"T541","span":{"begin":90,"end":266},"obj":"Sentence"},{"id":"T542","span":{"begin":267,"end":444},"obj":"Sentence"},{"id":"T543","span":{"begin":445,"end":770},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Povidone-iodine is a chemical complex of polyvinylpyrrolidone polymer and iodine (PVP-I). It is being tested in the U.S., France, United Kingdom, Singapore, and Malaysia as a gargle, mouthwash, or nasal spray to reduce nasopharyngeal viral load in COVID-19 patients. Reports have highlighted the virucidal effect of diluted PVP-I concentration (\u003c10%), without toxic effects on respiratory cilia, olfactory function, or mucosal appearance [250]. In this direction, in vitro studies of 0.23% PVP-I mouthwash suggested that, following a 15-s exposure, the solution can provide effective antiviral activity against influenza virus A (H1N1), MERS-CoV, rotavirus, and SARS-CoV as well as antibacterial activity against Klebsiella pneumoniae and Streptococcus pneumoniae [251]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2159","span":{"begin":257,"end":265},"obj":"Species"},{"id":"2160","span":{"begin":611,"end":626},"obj":"Species"},{"id":"2161","span":{"begin":630,"end":634},"obj":"Species"},{"id":"2162","span":{"begin":637,"end":645},"obj":"Species"},{"id":"2163","span":{"begin":662,"end":670},"obj":"Species"},{"id":"2164","span":{"begin":713,"end":734},"obj":"Species"},{"id":"2165","span":{"begin":739,"end":763},"obj":"Species"},{"id":"2166","span":{"begin":377,"end":388},"obj":"Species"},{"id":"2167","span":{"begin":0,"end":15},"obj":"Chemical"},{"id":"2168","span":{"begin":41,"end":61},"obj":"Chemical"},{"id":"2169","span":{"begin":62,"end":69},"obj":"Chemical"},{"id":"2170","span":{"begin":74,"end":80},"obj":"Chemical"},{"id":"2171","span":{"begin":82,"end":87},"obj":"Chemical"},{"id":"2172","span":{"begin":324,"end":329},"obj":"Chemical"},{"id":"2173","span":{"begin":248,"end":256},"obj":"Disease"}],"attributes":[{"id":"A2159","pred":"tao:has_database_id","subj":"2159","obj":"Tax:9606"},{"id":"A2160","pred":"tao:has_database_id","subj":"2160","obj":"Tax:11308"},{"id":"A2161","pred":"tao:has_database_id","subj":"2161","obj":"Tax:114727"},{"id":"A2162","pred":"tao:has_database_id","subj":"2162","obj":"Tax:1335626"},{"id":"A2163","pred":"tao:has_database_id","subj":"2163","obj":"Tax:694009"},{"id":"A2164","pred":"tao:has_database_id","subj":"2164","obj":"Tax:573"},{"id":"A2165","pred":"tao:has_database_id","subj":"2165","obj":"Tax:1313"},{"id":"A2166","pred":"tao:has_database_id","subj":"2166","obj":"Tax:12814"},{"id":"A2167","pred":"tao:has_database_id","subj":"2167","obj":"MESH:D011206"},{"id":"A2168","pred":"tao:has_database_id","subj":"2168","obj":"MESH:D011205"},{"id":"A2169","pred":"tao:has_database_id","subj":"2169","obj":"MESH:D011108"},{"id":"A2170","pred":"tao:has_database_id","subj":"2170","obj":"MESH:D007455"},{"id":"A2173","pred":"tao:has_database_id","subj":"2173","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Povidone-iodine is a chemical complex of polyvinylpyrrolidone polymer and iodine (PVP-I). It is being tested in the U.S., France, United Kingdom, Singapore, and Malaysia as a gargle, mouthwash, or nasal spray to reduce nasopharyngeal viral load in COVID-19 patients. Reports have highlighted the virucidal effect of diluted PVP-I concentration (\u003c10%), without toxic effects on respiratory cilia, olfactory function, or mucosal appearance [250]. In this direction, in vitro studies of 0.23% PVP-I mouthwash suggested that, following a 15-s exposure, the solution can provide effective antiviral activity against influenza virus A (H1N1), MERS-CoV, rotavirus, and SARS-CoV as well as antibacterial activity against Klebsiella pneumoniae and Streptococcus pneumoniae [251]."}