PMC:7600245 / 44897-45712
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T193 | 7-11 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T194 | 697-700 | Body_part | denotes | arm | http://purl.org/sig/ont/fma/fma24890 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T11 | 7-11 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T12 | 697-700 | Body_part | denotes | arm | http://purl.obolibrary.org/obo/UBERON_0001460 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T173 | 298-320 | Disease | denotes | ankylosing spondylitis | http://purl.obolibrary.org/obo/MONDO_0005306 |
| T174 | 309-320 | Disease | denotes | spondylitis | http://purl.obolibrary.org/obo/MONDO_0003937 |
| T175 | 322-330 | Disease | denotes | bursitis | http://purl.obolibrary.org/obo/MONDO_0002471 |
| T176 | 332-342 | Disease | denotes | tendonitis | http://purl.obolibrary.org/obo/MONDO_0004857 |
| T177 | 344-358 | Disease | denotes | osteoarthritis | http://purl.obolibrary.org/obo/MONDO_0005178 |
| T178 | 364-384 | Disease | denotes | rheumatoid arthritis | http://purl.obolibrary.org/obo/MONDO_0008383 |
| T179 | 375-384 | Disease | denotes | arthritis | http://purl.obolibrary.org/obo/MONDO_0005578 |
| T180 | 775-783 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T416 | 29-30 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T417 | 332-342 | http://www.ebi.ac.uk/cellline#tendon | denotes | tendonitis |
| T418 | 332-342 | http://www.ebi.ac.uk/efo/EFO_0000952 | denotes | tendonitis |
| T419 | 683-688 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
| T420 | 697-700 | http://www.ebi.ac.uk/efo/EFO_0001410 | denotes | arm |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T655 | 48-56 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T656 | 62-69 | Chemical | denotes | benzoyl | http://purl.obolibrary.org/obo/CHEBI_22733 |
| T657 | 70-90 | Chemical | denotes | indole-3-acetic acid | http://purl.obolibrary.org/obo/CHEBI_16411 |
| T658 | 70-76 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T660 | 79-90 | Chemical | denotes | acetic acid | http://purl.obolibrary.org/obo/CHEBI_15366 |
| T661 | 86-90 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T662 | 171-176 | Chemical | denotes | NSAID | http://purl.obolibrary.org/obo/CHEBI_35475 |
| T663 | 196-205 | Chemical | denotes | analgesic | http://purl.obolibrary.org/obo/CHEBI_35480 |
| T664 | 210-221 | Chemical | denotes | antipyretic | http://purl.obolibrary.org/obo/CHEBI_35493 |
| T665 | 532-545 | Chemical | denotes | prostaglandin | http://purl.obolibrary.org/obo/CHEBI_26333 |
| T666 | 636-654 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T667 | 659-671 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T668 | 683-688 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T76 | 519-528 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T32 | 272-276 | Phenotype | denotes | pain | http://purl.obolibrary.org/obo/HP_0012531 |
| T33 | 322-330 | Phenotype | denotes | bursitis | http://purl.obolibrary.org/obo/HP_0025232 |
| T34 | 332-342 | Phenotype | denotes | tendonitis | http://purl.obolibrary.org/obo/HP_0025230 |
| T35 | 344-358 | Phenotype | denotes | osteoarthritis | http://purl.obolibrary.org/obo/HP_0002758 |
| T36 | 364-384 | Phenotype | denotes | rheumatoid arthritis | http://purl.obolibrary.org/obo/HP_0001370 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T337 | 0-113 | Sentence | denotes | In one hand, indomethacin is a synthetic, small molecule of N-benzoyl-indole-3-acetic acid derivative (Figure 7). |
| T338 | 114-147 | Sentence | denotes | It was first approved by the U.S. |
| T339 | 148-177 | Sentence | denotes | FDA in 1984 for use as NSAID. |
| T340 | 178-233 | Sentence | denotes | It also possesses analgesic and antipyretic properties. |
| T341 | 234-277 | Sentence | denotes | It is used for acute mild to moderate pain. |
| T342 | 278-409 | Sentence | denotes | It is also used for ankylosing spondylitis, bursitis, tendonitis, osteoarthritis, and rheumatoid arthritis, among other conditions. |
| T343 | 410-563 | Sentence | denotes | The known mechanism is the reversible inhibition of cyclooxygenase-1 and 2 enzymes, which leads to decreased formation of prostaglandin precursors [142]. |
| T344 | 564-815 | Sentence | denotes | Orally administered indomethacin is being evaluated in combination with hydroxychloroquine and azithromycin in an open-label, single-arm, phase 2 study to determine its efficacy and safety in subjects with mild COVID-19 symptoms (NCT04344457; n = 80). |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1372 | 462-484 | Gene | denotes | cyclooxygenase-1 and 2 | Gene:5742 |
| 1373 | 13-25 | Chemical | denotes | indomethacin | MESH:D007213 |
| 1374 | 60-90 | Chemical | denotes | N-benzoyl-indole-3-acetic acid | |
| 1375 | 532-545 | Chemical | denotes | prostaglandin | MESH:D011453 |
| 1376 | 584-596 | Chemical | denotes | indomethacin | MESH:D007213 |
| 1377 | 636-654 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 1378 | 659-671 | Chemical | denotes | azithromycin | MESH:D017963 |
| 1379 | 272-276 | Disease | denotes | pain | MESH:D010146 |
| 1380 | 298-320 | Disease | denotes | ankylosing spondylitis | MESH:D013167 |
| 1381 | 322-330 | Disease | denotes | bursitis | MESH:D002062 |
| 1382 | 332-342 | Disease | denotes | tendonitis | MESH:D052256 |
| 1383 | 344-358 | Disease | denotes | osteoarthritis | MESH:D010003 |
| 1384 | 364-384 | Disease | denotes | rheumatoid arthritis | MESH:D001172 |
| 1385 | 775-783 | Disease | denotes | COVID-19 | MESH:C000657245 |