PMC:7600245 / 39126-39409
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T155 | 158-166 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T156 | 192-200 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T157 | 253-265 | Body_part | denotes | cell nucleus | http://purl.org/sig/ont/fma/fma63840 |
| T158 | 253-257 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T159 | 273-282 | Body_part | denotes | cytoplasm | http://purl.org/sig/ont/fma/fma66835 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T146 | 175-180 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T351 | 253-257 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T592 | 158-166 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T593 | 192-200 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T594 | 258-265 | Chemical | denotes | nucleus | http://purl.obolibrary.org/obo/CHEBI_33252 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T51 | 134-148 | http://purl.obolibrary.org/obo/GO_0051168 | denotes | nuclear export |
| T52 | 175-191 | http://purl.obolibrary.org/obo/GO_0051726 | denotes | tumor suppressor |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T22 | 175-180 | Phenotype | denotes | tumor | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T296 | 0-283 | Sentence | denotes | Specifically, selinexor selectively and irreversibly modifies the essential Cys528 residue in CRM1, and thus, it blocks CRM1-mediated nuclear export of cargo proteins such as tumor suppressor proteins (p21, p53, pRB, BRCA1/2, FOXO, and others) from the cell nucleus to the cytoplasm. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1169 | 94-98 | Gene | denotes | CRM1 | Gene:7514 |
| 1170 | 120-124 | Gene | denotes | CRM1 | Gene:7514 |
| 1171 | 202-205 | Gene | denotes | p21 | Gene:644914 |
| 1172 | 207-210 | Gene | denotes | p53 | Gene:7157 |
| 1173 | 212-215 | Gene | denotes | pRB | Gene:5925 |
| 1174 | 217-224 | Gene | denotes | BRCA1/2 | Gene:672 |
| 1177 | 76-82 | Chemical | denotes | Cys528 | |
| 1182 | 175-180 | Disease | denotes | tumor | MESH:D009369 |