PMC:7600245 / 32411-32637 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T294","span":{"begin":19,"end":25},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T295","span":{"begin":35,"end":38},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"In addition to the active site, it has been reported that the flexible darunavir binds to another site on the surface of the enzyme, which accounts for its resilience against potential mutations in the targeted protease [103]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T480","span":{"begin":71,"end":80},"obj":"Chemical"}],"attributes":[{"id":"A480","pred":"chebi_id","subj":"T480","obj":"http://purl.obolibrary.org/obo/CHEBI_367163"}],"text":"In addition to the active site, it has been reported that the flexible darunavir binds to another site on the surface of the enzyme, which accounts for its resilience against potential mutations in the targeted protease [103]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T236","span":{"begin":0,"end":226},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In addition to the active site, it has been reported that the flexible darunavir binds to another site on the surface of the enzyme, which accounts for its resilience against potential mutations in the targeted protease [103]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"936","span":{"begin":71,"end":80},"obj":"Chemical"}],"attributes":[{"id":"A936","pred":"tao:has_database_id","subj":"936","obj":"MESH:D000069454"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In addition to the active site, it has been reported that the flexible darunavir binds to another site on the surface of the enzyme, which accounts for its resilience against potential mutations in the targeted protease [103]."}