PMC:7600245 / 29703-29988 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T111","span":{"begin":239,"end":247},"obj":"Disease"}],"attributes":[{"id":"A111","pred":"mondo_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"estimated EC50 value of 26.63 μM [85]. Computational studies have also suggested that lopinavir may inhibit the viral main protease Mpro, perhaps by targeting its active site [86,87]. Earlier, lopinavir exhibited in vitro activity against SARS-CoV-1 and MERS-CoV [88,89,90]. It also sh"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T274","span":{"begin":31,"end":36},"obj":"http://purl.obolibrary.org/obo/CLO_0007488"},{"id":"T275","span":{"begin":163,"end":169},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T276","span":{"begin":222,"end":230},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"estimated EC50 value of 26.63 μM [85]. Computational studies have also suggested that lopinavir may inhibit the viral main protease Mpro, perhaps by targeting its active site [86,87]. Earlier, lopinavir exhibited in vitro activity against SARS-CoV-1 and MERS-CoV [88,89,90]. It also sh"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T421","span":{"begin":86,"end":95},"obj":"Chemical"},{"id":"T422","span":{"begin":193,"end":202},"obj":"Chemical"}],"attributes":[{"id":"A421","pred":"chebi_id","subj":"T421","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A422","pred":"chebi_id","subj":"T422","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"}],"text":"estimated EC50 value of 26.63 μM [85]. Computational studies have also suggested that lopinavir may inhibit the viral main protease Mpro, perhaps by targeting its active site [86,87]. Earlier, lopinavir exhibited in vitro activity against SARS-CoV-1 and MERS-CoV [88,89,90]. It also sh"}

{"project":"LitCovid-sentences","denotations":[{"id":"T219","span":{"begin":39,"end":183},"obj":"Sentence"},{"id":"T220","span":{"begin":184,"end":274},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"estimated EC50 value of 26.63 μM [85]. Computational studies have also suggested that lopinavir may inhibit the viral main protease Mpro, perhaps by targeting its active site [86,87]. Earlier, lopinavir exhibited in vitro activity against SARS-CoV-1 and MERS-CoV [88,89,90]. It also sh"}

{"project":"LitCovid-PubTator","denotations":[{"id":"846","span":{"begin":132,"end":136},"obj":"Gene"},{"id":"849","span":{"begin":239,"end":247},"obj":"Species"},{"id":"850","span":{"begin":254,"end":262},"obj":"Species"},{"id":"859","span":{"begin":86,"end":95},"obj":"Chemical"},{"id":"860","span":{"begin":193,"end":202},"obj":"Chemical"}],"attributes":[{"id":"A846","pred":"tao:has_database_id","subj":"846","obj":"Gene:8673700"},{"id":"A849","pred":"tao:has_database_id","subj":"849","obj":"Tax:694009"},{"id":"A850","pred":"tao:has_database_id","subj":"850","obj":"Tax:1335626"},{"id":"A859","pred":"tao:has_database_id","subj":"859","obj":"MESH:D061466"},{"id":"A860","pred":"tao:has_database_id","subj":"860","obj":"MESH:D061466"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"estimated EC50 value of 26.63 μM [85]. Computational studies have also suggested that lopinavir may inhibit the viral main protease Mpro, perhaps by targeting its active site [86,87]. Earlier, lopinavir exhibited in vitro activity against SARS-CoV-1 and MERS-CoV [88,89,90]. It also sh"}