> top > docs > PMC:7600245 > spans > 14064-15080 > annotations

PMC:7600245 / 14064-15080 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T68 407-410 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T69 790-793 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T48 555-563 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 567-579 Disease denotes Yellow Fever http://purl.obolibrary.org/obo/MONDO_0020502
T50 955-959 Disease denotes Zika http://purl.obolibrary.org/obo/MONDO_0018661
T51 961-973 Disease denotes Yellow Fever http://purl.obolibrary.org/obo/MONDO_0020502
T52 988-993 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T116 29-30 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T117 109-115 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T118 184-185 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T119 255-261 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T120 330-336 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T121 516-522 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T122 526-527 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T123 645-648 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T124 699-702 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T125 716-717 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T126 761-769 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T127 794-801 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T128 825-830 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T129 868-874 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T130 939-946 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T131 994-1001 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T131 59-68 Chemical denotes adenosine http://purl.obolibrary.org/obo/CHEBI_16335
T132 69-79 Chemical denotes nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T133 121-130 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T134 166-176 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T135 186-193 Chemical denotes prodrug http://purl.obolibrary.org/obo/CHEBI_50266
T136 270-293 Chemical denotes nucleoside triphosphate http://purl.obolibrary.org/obo/CHEBI_17326
T137 270-280 Chemical denotes nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T138 281-293 Chemical denotes triphosphate http://purl.obolibrary.org/obo/CHEBI_18036
T139 299-311 Chemical denotes triphosphate http://purl.obolibrary.org/obo/CHEBI_18036
T140 463-467 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T141 669-673 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T142 751-760 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T143 888-892 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T4 574-579 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T5 968-973 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T101 0-4 Sentence denotes 2.2.
T102 5-40 Sentence denotes Galidesivir (Immucillin-A, BCX4430)
T103 41-154 Sentence denotes Galidesivir is an adenosine nucleoside analog (Figure 3) that is an active site inhibitor of RdRp (EC50 < 50 µM).
T104 155-294 Sentence denotes Similar to remdesivir, it is a prodrug that is metabolized by cellular kinases to the corresponding active form of nucleoside triphosphate.
T105 295-458 Sentence denotes The triphosphate form binds to the active site of the viral enzyme and gets incorporated into the growing viral RNA chain resulting in premature chain termination.
T106 459-620 Sentence denotes The drug is being developed by BioCryst, U.S., and being tested in a phase 1 clinical trial for COVID-19 or Yellow Fever in Brazil in collaboration with the U.S.
T107 621-664 Sentence denotes NIAID (NCT03891420; n = 132) [44,45,46,47].
T108 665-864 Sentence denotes The drug is used parenterally and has demonstrated a broad-spectrum, showing in vitro antiviral activity against at least 20 RNA viruses across eight different virus families including coronaviruses.
T109 865-1016 Sentence denotes In animal studies, the drug was effective in protecting against dangerous viruses such as Zika, Yellow Fever, Marburg, and Ebola viruses [44,45,46,47].

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
333 5-16 Chemical denotes Galidesivir MESH:C517546
334 18-30 Chemical denotes Immucillin-A MESH:C517546
335 32-39 Chemical denotes BCX4430 MESH:C517546
344 134-138 Gene denotes RdRp Gene:43740578
345 41-52 Chemical denotes Galidesivir MESH:C517546
346 59-68 Chemical denotes adenosine MESH:D000241
347 166-176 Chemical denotes remdesivir MESH:C000606551
348 270-293 Chemical denotes nucleoside triphosphate
349 299-311 Chemical denotes triphosphate MESH:C005692
350 555-563 Disease denotes COVID-19 MESH:C000657245
351 574-579 Disease denotes Fever MESH:D005334
355 850-863 Species denotes coronaviruses Tax:11118
356 988-993 Species denotes Ebola Tax:1570291
357 968-973 Disease denotes Fever MESH:D005334