> top > docs > PMC:7598148 > annotations

PMC:7598148 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 25-29 Species denotes Girl Tax:9606
4 44-54 Species denotes SARS-CoV-2 Tax:2697049
5 30-38 Disease denotes Infected MESH:D007239
7 106-113 Species denotes Patient Tax:9606
9 152-160 Disease denotes COVID-19 MESH:C000657245
14 319-366 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
15 368-378 Species denotes SARS-CoV-2 Tax:2697049
16 740-750 Species denotes SARS-CoV-2 Tax:2697049
17 539-564 Disease denotes respiratory complications MESH:D012131
27 829-834 Species denotes woman Tax:9606
28 1103-1107 Species denotes girl Tax:9606
29 1132-1142 Species denotes SARS-CoV-2 Tax:2697049
30 881-901 Disease denotes respiratory symptoms MESH:D012818
31 905-923 Disease denotes COVID-19 pneumonia MESH:C000657245
32 948-968 Disease denotes SARS-CoV-2 infection MESH:C000657245
33 997-1035 Disease denotes immunodeficiency virus (HIV) infection MESH:D015658
34 1052-1060 Disease denotes diabetes MESH:D003920
35 1242-1251 Disease denotes infection MESH:D007239
41 1448-1452 Species denotes girl Tax:9606
42 1479-1489 Species denotes SARS-CoV-2 Tax:2697049
43 1560-1570 Species denotes SARS-CoV-2 Tax:2697049
44 1358-1376 Disease denotes COVID-19 pneumonia MESH:C000657245
45 1398-1418 Disease denotes SARS-CoV-2 infection MESH:C000657245
51 1593-1633 Species denotes acute respiratory syndrome coronavirus 2 Tax:2697049
52 1684-1697 Species denotes coronaviridae Tax:11118
53 1863-1888 Disease denotes respiratory complications MESH:D012131
54 1897-1916 Disease denotes respiratory failure MESH:D012131
55 2147-2155 Disease denotes infected MESH:D007239
66 2573-2583 Species denotes SARS-CoV-2 Tax:2697049
67 2594-2599 Species denotes women Tax:9606
68 2623-2633 Species denotes SARS-CoV-2 Tax:2697049
69 2956-2966 Species denotes SARS-CoV-2 Tax:2697049
70 3230-3237 Species denotes infants Tax:9606
71 3263-3273 Species denotes SARS-CoV-2 Tax:2697049
72 3317-3327 Species denotes outpatient Tax:9606
73 2515-2525 Disease denotes infections MESH:D007239
74 2942-2950 Disease denotes infected MESH:D007239
75 3660-3679 Disease denotes postnatal infection MESH:D019052
85 3721-3725 Species denotes girl Tax:9606
86 3869-3874 Species denotes woman Tax:9606
87 4007-4017 Species denotes SARS-COV-2 Tax:2697049
88 4301-4311 Species denotes SARS-CoV-2 Tax:2697049
89 3906-3909 Species denotes HIV Tax:12721
90 3824-3833 Disease denotes eclampsia MESH:D004461
91 3934-3942 Disease denotes diabetes MESH:D003920
92 4065-4084 Disease denotes shortness of breath MESH:D004417
93 4089-4096 Disease denotes myalgia MESH:D063806
98 4568-4575 Species denotes patient Tax:9606
99 4732-4739 Species denotes patient Tax:9606
100 4778-4788 Chemical denotes zidovudine MESH:D015215
101 4636-4648 Disease denotes hypoglycemia MESH:D007003
107 4836-4846 Species denotes SARS-COV-2 Tax:2697049
108 5059-5066 Species denotes patient Tax:9606
109 5160-5166 Chemical denotes oxygen MESH:D010100
110 5131-5151 Disease denotes respiratory distress MESH:D012128
111 5238-5263 Disease denotes respiratory deterioration MESH:D012131
114 5292-5299 Species denotes patient Tax:9606
115 5419-5429 Species denotes SARS-CoV-2 Tax:2697049
123 6446-6474 Species denotes Human immunodeficiency virus Tax:12721
124 6573-6583 Species denotes SARS-CoV-2 Tax:2697049
125 5774-5782 Disease denotes infected MESH:D007239
126 6164-6173 Disease denotes mortality MESH:D003643
127 6198-6210 Disease denotes organ injury MESH:D009102
128 6375-6385 Disease denotes infections MESH:D007239
129 6500-6507 Disease denotes Rubella MESH:D012409
133 7406-7416 Species denotes Zika virus Tax:64320
134 7287-7297 Disease denotes infections MESH:D007239
135 7431-7454 Disease denotes congenital microcephaly MESH:D008831
147 7781-7812 Gene denotes angiotensin-converting enzyme 2 Gene:59272
148 7814-7818 Gene denotes ACE2 Gene:59272
149 7967-7971 Gene denotes ACE2 Gene:59272
150 8082-8086 Gene denotes ACE2 Gene:59272
151 8484-8488 Gene denotes ACE2 Gene:59272
152 7654-7664 Species denotes SARS-CoV-2 Tax:2697049
153 7737-7747 Species denotes SARS-CoV-2 Tax:2697049
154 8349-8394 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
155 8457-8467 Species denotes SARS-CoV-2 Tax:2697049
156 8302-8317 Disease denotes fetal infection MESH:D005315
157 8446-8455 Disease denotes infection MESH:D007239
165 8607-8611 Gene denotes ACE2 Gene:59272
166 9026-9036 Species denotes SARS-CoV-2 Tax:2697049
167 9270-9280 Species denotes SARS-CoV-2 Tax:2697049
168 9372-9382 Species denotes SARS-CoV-2 Tax:2697049
169 8829-8839 Species denotes SARS-CoV-2 Tax:2697049
170 8937-8946 Disease denotes infection MESH:D007239
171 9439-9448 Disease denotes infection MESH:D007239
179 9648-9658 Species denotes SARS-CoV-2 Tax:2697049
180 9966-9976 Species denotes SARS-CoV-2 Tax:2697049
181 9559-9567 Disease denotes infected MESH:D007239
182 9751-9771 Disease denotes SARS-CoV-2 infection MESH:C000657245
183 10011-10019 Disease denotes infected MESH:D007239
184 10064-10073 Disease denotes infection MESH:D007239
185 10297-10306 Disease denotes infection MESH:D007239
198 10777-10782 Gene denotes ACE-2 Gene:59272
199 10570-10574 Species denotes girl Tax:9606
200 10601-10611 Species denotes SARS-CoV-2 Tax:2697049
201 10683-10693 Species denotes SARS-CoV-2 Tax:2697049
202 10695-10705 Species denotes SARS-CoV-2 Tax:2697049
203 10865-10875 Species denotes SARS-CoV-2 Tax:2697049
204 10977-10987 Species denotes SARS-COV-2 Tax:2697049
205 11197-11207 Species denotes SARS-CoV-2 Tax:2697049
206 10480-10498 Disease denotes COVID-19 pneumonia MESH:C000657245
207 10520-10540 Disease denotes SARS-CoV-2 infection MESH:C000657245
208 11059-11067 Disease denotes infected MESH:D007239
209 11130-11139 Disease denotes infection MESH:D007239
282 11374-11379 Species denotes woman Tax:9606
283 11463-11473 Species denotes SARS-CoV-2 Tax:2697049
284 11416-11434 Disease denotes COVID-19 pneumonia MESH:C000657245
285 11543-11558 Disease denotes viral pneumonia
291 12566-12576 Species denotes SARS-CoV-2 Tax:2697049
292 12228-12232 Chemical denotes urea MESH:D014508
293 12233-12241 Chemical denotes nitrogen MESH:D009584
294 12364-12371 Chemical denotes Glucose MESH:D005947
295 12393-12403 Chemical denotes Creatinine MESH:D003404
297 11697-11702 Species denotes woman Tax:9606
301 13354-13364 Species denotes SARS-CoV-2 Tax:2697049
302 13377-13380 Species denotes HIV Tax:12721
303 13517-13528 Chemical denotes Bicarbonate MESH:D001639
305 12851-12855 Species denotes girl Tax:9606
307 13595-13642 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
309 13648-13676 Species denotes human immunodeficiency virus Tax:12721
311 13721-13724 Chemical denotes CO2 MESH:D002245
313 13752-13754 Chemical denotes O2 MESH:D010100

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 914-923 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 997-1013 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T3 1040-1060 Phenotype denotes gestational diabetes http://purl.obolibrary.org/obo/HP_0009800
T4 1367-1376 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 1897-1916 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T6 3784-3799 Phenotype denotes oligohydramnios http://purl.obolibrary.org/obo/HP_0001562
T7 3824-3833 Phenotype denotes eclampsia http://purl.obolibrary.org/obo/HP_0100601
T8 3922-3942 Phenotype denotes gestational diabetes http://purl.obolibrary.org/obo/HP_0009800
T9 4065-4084 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T10 4089-4096 Phenotype denotes myalgia http://purl.obolibrary.org/obo/HP_0003326
T11 4636-4648 Phenotype denotes hypoglycemia http://purl.obolibrary.org/obo/HP_0001943
T12 5131-5151 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T13 6241-6272 Phenotype denotes intrauterine growth restriction http://purl.obolibrary.org/obo/HP_0001511
T14 6452-6468 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T15 7431-7454 Phenotype denotes congenital microcephaly http://purl.obolibrary.org/obo/HP_0011451
T16 10489-10498 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T17 11425-11434 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T18 11549-11558 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T19 13654-13670 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-95 Sentence denotes A Case of a Newborn Baby Girl Infected with SARS-CoV-2 Due to Transplacental Viral Transmission
T2 97-105 Sentence denotes Abstract
T3 106-114 Sentence denotes Patient:
T4 115-134 Sentence denotes Female, 31-year-old
T5 135-173 Sentence denotes Final Diagnosis: COVID-19 • SARS-CoV-2
T6 174-183 Sentence denotes Symptoms:
T7 184-196 Sentence denotes Asymptomatic
T8 197-209 Sentence denotes Medication:—
T9 210-231 Sentence denotes Clinical Procedure: —
T10 232-242 Sentence denotes Specialty:
T11 243-269 Sentence denotes Pediatrics and Neonatology
T12 271-281 Sentence denotes Objective:
T13 282-305 Sentence denotes Unusual clinical course
T14 307-318 Sentence denotes Background:
T15 319-453 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious virus and is responsible for the current pandemic.
T16 454-565 Sentence denotes It mainly infects cells of the lower respiratory tract and has been linked to severe respiratory complications.
T17 566-709 Sentence denotes Although multiple routes of transmission have been reported in the literature, there is no definitive evidence for transplacental transmission.
T18 710-793 Sentence denotes We present a case of neonatal SARS-CoV-2 likely due to transplacental transmission.
T19 795-807 Sentence denotes Case Report:
T20 808-969 Sentence denotes 31-year-old Hispanic woman in the final week of pregnancy developed mild respiratory symptoms of COVID-19 pneumonia and tested positive for SARS-CoV-2 infection.
T21 970-1061 Sentence denotes She had a history of Human immunodeficiency virus (HIV) infection and gestational diabetes.
T22 1062-1172 Sentence denotes Two days later, she gave birth to a baby girl who tested positive for SARS-CoV-2 on the first day after birth.
T23 1173-1269 Sentence denotes She was delivered via elective cesarean section adhering to a strict infection control protocol.
T24 1271-1283 Sentence denotes Conclusions:
T25 1284-1490 Sentence denotes This report presents a case of a 31-year-old mother with mild symptoms of COVID-19 pneumonia who was positive for SARS-CoV-2 infection and who gave birth to a baby girl who was also positive for SARS-CoV-2.
T26 1491-1571 Sentence denotes This case supports the possibility of transplacental transmission of SARS-CoV-2.
T27 1573-1583 Sentence denotes Background
T28 1584-1784 Sentence denotes Systemic acute respiratory syndrome coronavirus 2 (SARSCoV-2) is a highly infectious virus from the coronaviridae family and is responsible for the current pandemic which began late December 2019 [1].
T29 1785-1921 Sentence denotes The virus predominantly affects the respiratory system and can lead to severe respiratory complications such as respiratory failure [2].
T30 1922-2051 Sentence denotes At the moment, possible routes of transmission mentioned in the literature include droplet, fomite, and aerosol transmission [3].
T31 2052-2254 Sentence denotes Recent studies have investigated the possibility of vertical transmission of SARSCoV-2 from an infected mother to her fetus; however, there is limited evidence in support of transplacental transmission.
T32 2255-2584 Sentence denotes In response to the potential risks to both the mother and fetus, the American College of Obstetricians and Gynecologists, the American Academy of Pediatrics, and the Centers for Disease Control have developed guidelines which provide a framework for detecting infections early and preventing potential transmission of SARS-CoV-2.
T33 2585-2732 Sentence denotes Pregnant women admitted for suspected SARS-CoV-2 or who develop symptoms during admission are isolated and should be prioritized for testing [4,5].
T34 2733-2916 Sentence denotes Furthermore, delivery should be performed in a negative-pressure isolation ward whenever possible, with strict precautionary measures to reduce the risk of droplet transmission [6,7].
T35 2917-3080 Sentence denotes Neonates born to mothers infected with SARS-CoV-2 should be screened at 24 and 48 h of age using nasopharyngeal swabs for polymerase chain reaction (PCR) analysis.
T36 3081-3203 Sentence denotes Any positive result requires repeated testing at 48- to 72-h intervals until there are 2 consecutive negative results [6].
T37 3204-3372 Sentence denotes Furthermore, asymptomatic infants with positive or pending SARS-CoV-2 tests may be discharged home with plans of outpatient observation through 14 days after birth [6].
T38 3373-3686 Sentence denotes Clinical staff caring for the mother and infant should use droplet and contact precautions, including the use of personal protective equipment such as gown, gloves, eye protection, and standard surgical mask [4–7] in addition to separating the mother and newborn to minimize the risk of postnatal infection [6,7].
T39 3688-3699 Sentence denotes Case Report
T40 3700-3834 Sentence denotes A 1-day-old Hispanic girl was born via elective cesarean section at 34 weeks due to oligohydramnios and maternal history of eclampsia.
T41 3835-3943 Sentence denotes Her mother was a 31-year-old G2P2 woman with a past medical history of HIV and type A2 gestational diabetes.
T42 3944-4097 Sentence denotes Two days prior to giving birth, her mother tested positive for SARS-COV-2 via nasopharyngeal swab PCR after experiencing shortness of breath and myalgia.
T43 4098-4323 Sentence denotes Upon admission to the hospital, initial laboratory studies revealed a white blood cell count (WBC) of 10 000 cells/mm3 (Table 1) and a chest X-ray showed bibasilar opacities, supporting her diagnosis of SARS-CoV-2 (Figure 1).
T44 4324-4415 Sentence denotes Initial examination of the neonate was normal and the Apgar score was 9/10 at 1 and 5 mins.
T45 4416-4531 Sentence denotes Vital signs were within normal limits and a complete blood count revealed a normal WBC of 9000 cells/mm3 (Table 2).
T46 4532-4727 Sentence denotes Due to the above circumstances, the patient was admitted to the Neonatal Intensive Care Unit (NICU) for hypoglycemia monitoring and continuous cardiac, respiratory, and pulse oximetry monitoring.
T47 4728-4789 Sentence denotes The patient was also started on prophylactic oral zidovudine.
T48 4790-5041 Sentence denotes As per guidelines, the neonate was tested for SARS-COV-2 at 24 h of age via nasopharyngeal swab with the Becton-Dickinson (BD MAX) automated polymerase chain reaction system (Becton-Dickinson, Franklin Lakes, NJ, USA), which yielded a positive result.
T49 5042-5190 Sentence denotes At the time, the patient’s lungs were clear to auscultation bilaterally with no signs of respiratory distress and 95% oxygen saturation on room air.
T50 5191-5264 Sentence denotes She continued to be monitored for any signs of respiratory deterioration.
T51 5265-5352 Sentence denotes Over the next 10 days, the patient continued to be monitored and remained asymptomatic.
T52 5353-5491 Sentence denotes Laboratory results remained within normal limits, and testing for SARS-CoV-2 remained positive when repeated at 48 h and at 7 days of age.
T53 5492-5558 Sentence denotes She continued to feed well and grow appropriately during her stay.
T54 5559-5695 Sentence denotes No imaging studies were required and she was subsequently discharged from the NICU on day 10 with instructions for follow-up in 2 weeks.
T55 5697-5707 Sentence denotes Discussion
T56 5708-5807 Sentence denotes Vertical transmission is the passage of infectious agents from an infected mother to her offspring.
T57 5808-5913 Sentence denotes This may occur across the placenta, through breastmilk, or from direct contact during or after birth [8].
T58 5914-6116 Sentence denotes Concerning transplacental vertical transmission, disease-causing organisms overcome the protective barrier to infect the offspring during the antenatal, perinatal, or postnatal periods of gestation [8].
T59 6117-6308 Sentence denotes The result often increases fetal morbidity and mortality from complications like organ injury, morphological abnormalities, intrauterine growth restriction, and intrauterine fetal demise [9].
T60 6309-6419 Sentence denotes As a result, trimester-specific pregnancy screenings are done for infections with known vertical transmission.
T61 6420-6550 Sentence denotes These include Parvovirus, Human immunodeficiency virus, Zika, Varicella-zoster, Rubella, Cytomegalovirus, and Toxoplasmosis [8,9].
T62 6551-6661 Sentence denotes Due to the novelty of SARS-CoV-2, there is insufficient evidence on transplacental transmission of this virus.
T63 6662-6732 Sentence denotes Nonetheless, there are proposed mechanisms by which it may take place.
T64 6733-6862 Sentence denotes Understanding the structure and function of the placenta is essential when considering mechanisms of transplacental transmission.
T65 6863-7065 Sentence denotes The placenta is the interface between the maternal and fetal circulatory systems and is composed of fetal-derived progenitor cells which differentiate into cytotrophoblasts and syncytiotrophoblasts [8].
T66 7066-7182 Sentence denotes It is needed for fetal nourishment and protection against pathogens that may be present in the maternal circulation.
T67 7183-7302 Sentence denotes It is believed that the syncytiotropho-blast layer confers a broad non-specific resistance to microbial infections [8].
T68 7303-7387 Sentence denotes However, some pathogens are able to overcome this barrier through unique mechanisms.
T69 7388-7606 Sentence denotes For instance, the Zika virus, which causes congenital microcephaly, may be able to penetrate the placenta due to its ability to infect different cells of the placenta as well as cells of the maternal immune system [8].
T70 7607-7736 Sentence denotes With regards to transplacental transmission of SARS-CoV-2, it is essential to understand how the virus infects cells of the body.
T71 7737-7861 Sentence denotes SARS-CoV-2 infects host cells by binding to angiotensin-converting enzyme 2 (ACE2), a membrane-bound aminopeptidase [10,11].
T72 7862-7960 Sentence denotes This leads to receptor-mediated endocytosis of the virus, which is necessary for replication [11].
T73 7961-8152 Sentence denotes While ACE2 is predominantly expressed in the heart, lungs, kidneys, and gastrointestinal tract, recent studies uncovered ACE2 expression in various placental tissues and fetal organs [10–12].
T74 8153-8318 Sentence denotes While this expression is low in early gestational ages, it increases significantly in later stages of pregnancy [11], thereby increasing the risk of fetal infection.
T75 8319-8584 Sentence denotes Although similar viruses like severe acute respiratory syndrome coronavirus 1 have not demonstrated the ability to cause fetal infection, SARS-CoV-2 is able to bind ACE2 with much higher affinity [11], thus increasing the probability of transplacental transmission.
T76 8585-8756 Sentence denotes While the presence of ACE2 in the placenta provides a plausible mechanism for transplacental transmission, only 3 studies have found evidence in support of its occurrence.
T77 8757-8884 Sentence denotes Dong et al. described a case of a newborn that tested positive for anti-SARS-CoV-2 immunoglobulin M (IgM) 2 h after birth [13].
T78 8885-8983 Sentence denotes This class of antibody dominates the early phase of infection and is unable to cross the placenta.
T79 8984-9109 Sentence denotes Although this neonate tested negative for SARS-CoV-2, the positive IgM antibodies suggest an immune response of fetal origin.
T80 9110-9232 Sentence denotes Furthermore, intrapartum exposure was unlikely to be the cause since IgM may take up to 3 to 7 days to be detectable [13].
T81 9233-9343 Sentence denotes Additionally, other studies detected SARS-CoV-2 in placental tissue using electron microscopy and PCR [14,15].
T82 9344-9449 Sentence denotes This provides evidence that SARS-CoV-2 is able to infect the placenta and possibly cause fetal infection.
T83 9450-9581 Sentence denotes However, in a recent study, researchers were unable to detect viral particles in products of conception from infected mothers [16].
T84 9582-9659 Sentence denotes Furthermore, all babies born to these mothers tested negative for SARS-CoV-2.
T85 9660-9772 Sentence denotes These findings suggest that, in most cases, the placenta is able to protect the fetus from SARS-CoV-2 infection.
T86 9773-9878 Sentence denotes This also explains the paucity of reported cases suspicious for transplacental transmission of SARSCoV-2.
T87 9879-10033 Sentence denotes At this time, the literature identifies 3 other cases of neonates testing positive for SARS-CoV-2 as early as 16 h after birth from infected mothers [17].
T88 10034-10155 Sentence denotes Similar to our case, a strict infection control protocol was followed and the babies were delivered via cesarean section.
T89 10156-10398 Sentence denotes Although no products of conception in these cases were tested for viral particles, the positive PCR results within the first 24 h and strict infection control protocol make transplacental transmission more likely than peripartum transmission.
T90 10400-10411 Sentence denotes Conclusions
T91 10412-10612 Sentence denotes We presented the case of a 31-year-old mother with mild symptoms of COVID-19 pneumonia who was positive for SARS-CoV-2 infection and who gave birth to a baby girl who was also positive for SARS-CoV-2.
T92 10613-10694 Sentence denotes This case supports the possibility of trans-placental transmission of SARS-CoV-2.
T93 10695-10826 Sentence denotes SARS-CoV-2 can likely overcome the placental barrier though its high affinity for ACE-2 expressed in the placenta and fetal organs.
T94 10827-10917 Sentence denotes This is supported by the detection of SARS-CoV-2 in placental tissue and fetal IgM titers.
T95 10918-11089 Sentence denotes However, there are few cases suspicious for transplacental SARS-COV-2 transmission, suggesting that the placenta can protect the fetus of an infected mother in most cases.
T96 11090-11271 Sentence denotes Despite limited evidence, when a strict infection control protocol is followed during delivery, a positive SARS-CoV-2 test in a neonate is likely due to transplacental transmission.
T97 11273-11293 Sentence denotes Conflict of interest
T98 11294-11299 Sentence denotes None.
T99 11301-11310 Sentence denotes Figure 1.
T100 11312-11503 Sentence denotes 0The chest X-ray (anterior-posterior view) from a 31-year-old woman who presented with mild symptoms of COVID-19 pneumonia and who tested positive for SARS-CoV-2 two days before giving birth.
T101 11504-11624 Sentence denotes The lungs show changes consistent with viral pneumonia and include reduced lung expansion and bilateral basal opacities.
T102 11625-11633 Sentence denotes Table 1.
T103 11635-11730 Sentence denotes The results of the laboratory investigations of a 31-year-old woman 2 days before giving birth.
T104 11731-11769 Sentence denotes Variables Reference ranges Results
T105 11770-11807 Sentence denotes Complete blood count and differential
T106 11808-11842 Sentence denotes Hemoglobin (g/dL) 12.0–16.0 11.7
T107 11843-11889 Sentence denotes White-cell count (per mm3) 4.5–11.0 10.0×103
T108 11890-11928 Sentence denotes Red-cell count (g/dL) 12.0–16.0 11.7
T109 11929-11956 Sentence denotes Hematocrit (%) 36–46 35.0
T110 11957-12001 Sentence denotes Platelet count (per mm3) 140–440 203 K/mm3
T111 12002-12058 Sentence denotes Absolute lymphocyte count (per mm3) 0.90–4.60 0.93×103
T112 12059-12076 Sentence denotes Routine chemistry
T113 12077-12105 Sentence denotes Sodium (mEq/L) 135–145 136
T114 12106-12137 Sentence denotes Potassium (mEq/L) 3.5–5.0 4.3
T115 12138-12167 Sentence denotes Chloride (mEq/L) 98–107 104
T116 12168-12190 Sentence denotes CO2 (mEq/L) 21–31 22
T117 12191-12221 Sentence denotes Calcium (mg/dL) 8.6–10.3 8.5
T118 12222-12258 Sentence denotes Blood urea nitrogen(mg/dL) 7–23 11
T119 12259-12296 Sentence denotes C-Reactive protein (mg/L) ≤9.9 87.2
T120 12297-12328 Sentence denotes D-dimer (mcg/mL FFU) ≤0.50 99
T121 12329-12363 Sentence denotes Ferritin (ng/mL) 14.0–233.0 76.0
T122 12364-12392 Sentence denotes Glucose (mg/dL) 70–100 227
T123 12393-12428 Sentence denotes Creatinine (mg/dL) 0.60–1.30 0.50
T124 12429-12465 Sentence denotes Total bilirubin (g/dL) 6.4–8.4 6.4
T125 12466-12512 Sentence denotes Aspartate aminotransferase (unit/L) 13–39 19
T126 12513-12556 Sentence denotes Alanine aminotransferase (unit/L) 7–52 12
T127 12557-12565 Sentence denotes Serology
T128 12566-12588 Sentence denotes SARS-CoV-2* Positive
T129 12589-12614 Sentence denotes Urine analysis (dipstick)
T130 12615-12635 Sentence denotes Urine color Yellow
T131 12636-12660 Sentence denotes urine appearance Clear
T132 12661-12683 Sentence denotes Urine blood Negative
T133 12684-12709 Sentence denotes Urine nitrates Negative
T134 12710-12734 Sentence denotes Urine leukocytes Trace
T135 12735-12785 Sentence denotes * Severe acute respiratory syndrome coronavirus 2
T136 12786-12794 Sentence denotes Table 2.
T137 12796-12882 Sentence denotes The results of the laboratory investigations of a baby girl on the first day of birth.
T138 12883-12921 Sentence denotes Variables Reference ranges Results
T139 12922-12959 Sentence denotes Complete blood count and differential
T140 12960-12994 Sentence denotes Hemoglobin (g/dL) 14.5–22.5 20.9
T141 12995-13040 Sentence denotes White-cell count (per mm3) 9.4–34.0 9.0×103
T142 13041-13083 Sentence denotes Red-cell count (g/dL) 4.74–6.30 5.68×103
T143 13084-13115 Sentence denotes Hematocrit (%) 45.0–67.0 58.9
T144 13116-13158 Sentence denotes Platelet count (per mm3) 140–440 355×103
T145 13159-13215 Sentence denotes Absolute lymphocyte count (per mm3) 0.90–4.60 2.43×103
T146 13216-13254 Sentence denotes Total bilirubin (mg/dL) 0.3–1.1 10.2
T147 13255-13301 Sentence denotes Aspartate aminotransferase (unit/L) 13–39 37
T148 13302-13344 Sentence denotes Alanine aminotransferase (unit/L) 7–52 8
T149 13345-13353 Sentence denotes Serology
T150 13354-13376 Sentence denotes SARS-CoV-2* Positive
T151 13377-13397 Sentence denotes HIV-RNA** Negative
T152 13398-13441 Sentence denotes Arterial blood gasses (cord/arterial blood)
T153 13442-13461 Sentence denotes pH 7.36–7.44 7.30
T154 13462-13488 Sentence denotes PCO2 *** (mmHg) 36–44 49
T155 13489-13516 Sentence denotes PO2 **** (mmHg) 80–100 29
T156 13517-13554 Sentence denotes Bicarbonate (mmol/L) 22.0–26.0 24.1
T157 13555-13591 Sentence denotes Base excess (mmol/L) −2.0–3.0 −2.8
T158 13592-13643 Sentence denotes * Severe acute respiratory syndrome coronavirus 2;
T159 13644-13695 Sentence denotes ** human immunodeficiency virus- ribonucleic acid;
T160 13696-13725 Sentence denotes *** partial pressure of CO2;
T161 13726-13754 Sentence denotes **** partial pressure of O2