PMC:7594251 / 72191-73084
Annnotations
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T509 | 32-33 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T510 | 158-165 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T511 | 158-165 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T512 | 181-182 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T513 | 323-324 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T514 | 583-584 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T515 | 626-627 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T516 | 782-783 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T82904 | 34-39 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T68158 | 90-98 | Chemical | denotes | electron | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T245 | 158-175 | Chemical | denotes | organic compounds | http://purl.obolibrary.org/obo/CHEBI_50860|http://purl.obolibrary.org/obo/CHEBI_72695 |
| T85584 | 222-232 | Chemical | denotes | lanthanide | http://purl.obolibrary.org/obo/CHEBI_33319 |
| T42562 | 331-334 | Chemical | denotes | ion | http://purl.obolibrary.org/obo/CHEBI_24870 |
| T60918 | 456-465 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T47900 | 534-541 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T99644 | 606-610 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T64740 | 702-706 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T92435 | 863-867 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 704 | 222-232 | Chemical | denotes | lanthanide | MESH:D028581 |
| 705 | 325-330 | Chemical | denotes | metal | MESH:D008670 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T483 | 0-286 | Sentence | denotes | PNMR depends on the presence of a group (called the paramagnetic center) with an unpaired electron [343], and since many naturally occurring biomolecules and organic compounds lack a paramagnetic center, one such as caged lanthanide (CLaNP) [344], must be introduced artificially [341]. |
| T484 | 287-472 | Sentence | denotes | Once the paramagnetic center (often a metal ion) is present, paramagnetic effects can be used to measure the distance and the relative orientation (i.e., angle) between molecules [345]. |
| T485 | 473-562 | Sentence | denotes | This information is crucial when it comes to determining how ligands and substrates bind. |
| T486 | 563-659 | Sentence | denotes | Thus, PNMR is quite a useful technique for drug discovery when a paramagnetic center is present. |
| T487 | 660-893 | Sentence | denotes | The most relevant consequence of PNMR for drug discovery is paramagnetic relaxation enhancement (PRE), although there are a number of studies demonstrating the use of pseudocontact shift (PCS) effect in drug discovery research [341]. |