PMC:7594251 / 6347-6564 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T60513","span":{"begin":120,"end":133},"obj":"Body_part"},{"id":"T80219","span":{"begin":209,"end":216},"obj":"Body_part"}],"attributes":[{"id":"A1647","pred":"fma_id","subj":"T60513","obj":"http://purl.org/sig/ont/fma/fma82760"},{"id":"A14418","pred":"fma_id","subj":"T80219","obj":"http://purl.org/sig/ont/fma/fma54527"}],"text":"ased screening to create the first inhibitor candidate for BACE-1 in Alzheimer’s disease. BACE-1 is a membrane-anchored aspartic acid protease and is responsible for the production of amyloid beta peptides in neurons "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T9","span":{"begin":69,"end":88},"obj":"Disease"},{"id":"T10","span":{"begin":184,"end":191},"obj":"Disease"}],"attributes":[{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0004975"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"}],"text":"ased screening to create the first inhibitor candidate for BACE-1 in Alzheimer’s disease. BACE-1 is a membrane-anchored aspartic acid protease and is responsible for the production of amyloid beta peptides in neurons "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T10521","span":{"begin":100,"end":101},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T91269","span":{"begin":102,"end":110},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T7501","span":{"begin":184,"end":205},"obj":"http://purl.obolibrary.org/obo/PR_000036193"}],"text":"ased screening to create the first inhibitor candidate for BACE-1 in Alzheimer’s disease. BACE-1 is a membrane-anchored aspartic acid protease and is responsible for the production of amyloid beta peptides in neurons "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T35","span":{"begin":35,"end":44},"obj":"Chemical"},{"id":"T36","span":{"begin":120,"end":133},"obj":"Chemical"},{"id":"T37","span":{"begin":129,"end":133},"obj":"Chemical"},{"id":"T38","span":{"begin":184,"end":196},"obj":"Chemical"},{"id":"T39","span":{"begin":192,"end":196},"obj":"Chemical"},{"id":"T40","span":{"begin":197,"end":205},"obj":"Chemical"}],"attributes":[{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_22660"},{"id":"A37","pred":"chebi_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_64645"},{"id":"A39","pred":"chebi_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"},{"id":"A40","pred":"chebi_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"ased screening to create the first inhibitor candidate for BACE-1 in Alzheimer’s disease. BACE-1 is a membrane-anchored aspartic acid protease and is responsible for the production of amyloid beta peptides in neurons "}

{"project":"LitCovid-PubTator","denotations":[{"id":"44","span":{"begin":59,"end":65},"obj":"Gene"},{"id":"45","span":{"begin":90,"end":96},"obj":"Gene"},{"id":"46","span":{"begin":184,"end":196},"obj":"Gene"},{"id":"52","span":{"begin":69,"end":88},"obj":"Disease"}],"attributes":[{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"Gene:23621"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:23621"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Gene:351"},{"id":"A52","pred":"tao:has_database_id","subj":"52","obj":"MESH:D000544"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ased screening to create the first inhibitor candidate for BACE-1 in Alzheimer’s disease. BACE-1 is a membrane-anchored aspartic acid protease and is responsible for the production of amyloid beta peptides in neurons "}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":69,"end":88},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002511"}],"text":"ased screening to create the first inhibitor candidate for BACE-1 in Alzheimer’s disease. BACE-1 is a membrane-anchored aspartic acid protease and is responsible for the production of amyloid beta peptides in neurons "}