PMC:7594251 / 58706-60590
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T45014 | 1399-1405 | Body_part | denotes | radius | http://purl.org/sig/ont/fma/fma23463 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T416 | 74-75 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T417 | 182-183 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T418 | 302-303 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T419 | 439-440 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T420 | 479-481 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T421 | 617-618 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T422 | 635-636 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T423 | 669-670 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T424 | 764-765 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T425 | 925-926 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T426 | 1249-1251 | http://purl.obolibrary.org/obo/CLO_0008882 | denotes | rs |
| T427 | 1259-1261 | http://purl.obolibrary.org/obo/CLO_0007074 | denotes | kb |
| T428 | 1259-1261 | http://purl.obolibrary.org/obo/CLO_0051988 | denotes | kb |
| T429 | 1376-1378 | http://purl.obolibrary.org/obo/CLO_0008882 | denotes | rs |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T13908 | 49-58 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T65523 | 62-70 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T77901 | 266-275 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T44364 | 328-337 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T54940 | 578-587 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T98254 | 766-774 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T41807 | 927-935 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T5723 | 1035-1043 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T94243 | 1105-1114 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T55009 | 1352-1360 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T29865 | 1413-1421 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T41724 | 1520-1529 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T11659 | 25-38 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translational |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T409 | 0-118 | Sentence | denotes | Diffusion is the random, translational motion of molecules in solution as a consequence of their thermal energy [285]. |
| T410 | 119-282 | Sentence | denotes | This type of motion is often referred to as “Brownian motion”, a motion that describes molecular movement induced by random collisions between the molecules [286]. |
| T411 | 283-482 | Sentence | denotes | In the presence of a concentration gradient, molecules will naturally move from places of higher concentration to places of lower concentration [287] after a period of time, t, as shown in Figure 11. |
| T412 | 483-543 | Sentence | denotes | Fick’s Law can be used to model this type of movement [288]. |
| T413 | 544-743 | Sentence | denotes | The distribution of the diffusing molecules is accurately represented by a Gaussian curve, a normal distribution centered at a single point, which gradually “flattens” as t approaches infinity [213]. |
| T414 | 744-839 | Sentence | denotes | The extent to which a molecule diffuses is directly related to its shape, size, and mass [285]. |
| T415 | 840-1073 | Sentence | denotes | In homogeneous isotropic solutions, the root mean square distance (zrms) traveled by a molecule is given by following equation [289,290]:zrms=(2Dt)12 where D is the diffusion coefficient of the molecule, and t is the diffusion time. |
| T416 | 1074-1428 | Sentence | denotes | Making the assumption that the molecules are solid rigid spheres, the value of D can be calculated according to the famous Einstein-Stokes equation (Equation (2)):(4) D=kbT6πηrs where kb is the Boltzmann’s constant (1.3807 × 10−23 J/K), T is the absolute temperature, η is the solution viscosity, and rs is the hydrodynamic radius of the molecule [290]. |
| T417 | 1429-1671 | Sentence | denotes | Equation (1) and Equation (2), however, are not universally applicable; they only apply to molecules that are freely diffusing in isotropic, homogeneous solutions, and importantly that can be accurately described as hard, rigid spheres [285]. |
| T418 | 1672-1884 | Sentence | denotes | Different molecular geometries and additional modes of diffusion (i.e., restricted and anisotropic) require more advanced mathematics and theory [291,292], but the essential concepts of diffusion remain the same. |