PMC:7594251 / 34372-35422 JSONTXT

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T24","span":{"begin":616,"end":620},"obj":"Body_part"}],"attributes":[{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0002535"}],"text":"This pulse sequence is explained with the following steps: First, application of a 90° RF pulse creates a transverse (xy plane) magnetization. Second, a spin-echo period (delay-180°-delay block) is responsible for Mx/y magnetization decay. This period is repeated “n’’ times (CPMG building blocks). It is essential to point out that every NMR experiment involving a large number of pulses (e. g. due to the repeating building blocks) is likely to be sensitive to hardware restrictions and small miscalibrations of the duration of the applied pulses. To attenuate the unwanted effects of miscalibrations, Meiboom and Gill modified the previously used Carr–Purcell sequence [171] by changing the phase of the applied 180° pulses from x to y [172]. This procedure can be used to measure T2 relaxation times of any type of nuclei. For instance, in the case of 13C, all pulses and acquisitions are applied on 13C channel, while broadband proton decoupling is applied during all pulse sequences. It works analogically for different NMR-active nuclei [173]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T99850","span":{"begin":81,"end":82},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T53426","span":{"begin":104,"end":105},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T70539","span":{"begin":151,"end":152},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T40931","span":{"begin":364,"end":365},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T32172","span":{"begin":616,"end":620},"obj":"http://purl.obolibrary.org/obo/UBERON_0002535"},{"id":"T47725","span":{"begin":784,"end":786},"obj":"http://purl.obolibrary.org/obo/CLO_0050160"},{"id":"T26340","span":{"begin":1030,"end":1036},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"This pulse sequence is explained with the following steps: First, application of a 90° RF pulse creates a transverse (xy plane) magnetization. Second, a spin-echo period (delay-180°-delay block) is responsible for Mx/y magnetization decay. This period is repeated “n’’ times (CPMG building blocks). It is essential to point out that every NMR experiment involving a large number of pulses (e. g. due to the repeating building blocks) is likely to be sensitive to hardware restrictions and small miscalibrations of the duration of the applied pulses. To attenuate the unwanted effects of miscalibrations, Meiboom and Gill modified the previously used Carr–Purcell sequence [171] by changing the phase of the applied 180° pulses from x to y [172]. This procedure can be used to measure T2 relaxation times of any type of nuclei. For instance, in the case of 13C, all pulses and acquisitions are applied on 13C channel, while broadband proton decoupling is applied during all pulse sequences. It works analogically for different NMR-active nuclei [173]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T338","span":{"begin":66,"end":77},"obj":"Chemical"},{"id":"T339","span":{"begin":87,"end":89},"obj":"Chemical"},{"id":"T340","span":{"begin":784,"end":786},"obj":"Chemical"},{"id":"T342","span":{"begin":819,"end":825},"obj":"Chemical"},{"id":"T343","span":{"begin":933,"end":939},"obj":"Chemical"},{"id":"T344","span":{"begin":1037,"end":1043},"obj":"Chemical"}],"attributes":[{"id":"A338","pred":"chebi_id","subj":"T338","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A339","pred":"chebi_id","subj":"T339","obj":"http://purl.obolibrary.org/obo/CHEBI_73818"},{"id":"A340","pred":"chebi_id","subj":"T340","obj":"http://purl.obolibrary.org/obo/CHEBI_29298"},{"id":"A341","pred":"chebi_id","subj":"T340","obj":"http://purl.obolibrary.org/obo/CHEBI_75710"},{"id":"A342","pred":"chebi_id","subj":"T342","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A343","pred":"chebi_id","subj":"T343","obj":"http://purl.obolibrary.org/obo/CHEBI_24636"},{"id":"A344","pred":"chebi_id","subj":"T344","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"}],"text":"This pulse sequence is explained with the following steps: First, application of a 90° RF pulse creates a transverse (xy plane) magnetization. Second, a spin-echo period (delay-180°-delay block) is responsible for Mx/y magnetization decay. This period is repeated “n’’ times (CPMG building blocks). It is essential to point out that every NMR experiment involving a large number of pulses (e. g. due to the repeating building blocks) is likely to be sensitive to hardware restrictions and small miscalibrations of the duration of the applied pulses. To attenuate the unwanted effects of miscalibrations, Meiboom and Gill modified the previously used Carr–Purcell sequence [171] by changing the phase of the applied 180° pulses from x to y [172]. This procedure can be used to measure T2 relaxation times of any type of nuclei. For instance, in the case of 13C, all pulses and acquisitions are applied on 13C channel, while broadband proton decoupling is applied during all pulse sequences. It works analogically for different NMR-active nuclei [173]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"508","span":{"begin":650,"end":654},"obj":"Gene"},{"id":"509","span":{"begin":153,"end":157},"obj":"Gene"},{"id":"510","span":{"begin":856,"end":859},"obj":"Chemical"},{"id":"511","span":{"begin":904,"end":907},"obj":"Chemical"}],"attributes":[{"id":"A508","pred":"tao:has_database_id","subj":"508","obj":"Gene:407"},{"id":"A509","pred":"tao:has_database_id","subj":"509","obj":"Gene:10927"},{"id":"A510","pred":"tao:has_database_id","subj":"510","obj":"MESH:C000615229"},{"id":"A511","pred":"tao:has_database_id","subj":"511","obj":"MESH:C000615229"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This pulse sequence is explained with the following steps: First, application of a 90° RF pulse creates a transverse (xy plane) magnetization. Second, a spin-echo period (delay-180°-delay block) is responsible for Mx/y magnetization decay. This period is repeated “n’’ times (CPMG building blocks). It is essential to point out that every NMR experiment involving a large number of pulses (e. g. due to the repeating building blocks) is likely to be sensitive to hardware restrictions and small miscalibrations of the duration of the applied pulses. To attenuate the unwanted effects of miscalibrations, Meiboom and Gill modified the previously used Carr–Purcell sequence [171] by changing the phase of the applied 180° pulses from x to y [172]. This procedure can be used to measure T2 relaxation times of any type of nuclei. For instance, in the case of 13C, all pulses and acquisitions are applied on 13C channel, while broadband proton decoupling is applied during all pulse sequences. It works analogically for different NMR-active nuclei [173]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T238","span":{"begin":0,"end":58},"obj":"Sentence"},{"id":"T239","span":{"begin":59,"end":142},"obj":"Sentence"},{"id":"T240","span":{"begin":143,"end":239},"obj":"Sentence"},{"id":"T241","span":{"begin":240,"end":298},"obj":"Sentence"},{"id":"T242","span":{"begin":299,"end":549},"obj":"Sentence"},{"id":"T243","span":{"begin":550,"end":745},"obj":"Sentence"},{"id":"T244","span":{"begin":746,"end":826},"obj":"Sentence"},{"id":"T245","span":{"begin":827,"end":989},"obj":"Sentence"},{"id":"T246","span":{"begin":990,"end":1050},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This pulse sequence is explained with the following steps: First, application of a 90° RF pulse creates a transverse (xy plane) magnetization. Second, a spin-echo period (delay-180°-delay block) is responsible for Mx/y magnetization decay. This period is repeated “n’’ times (CPMG building blocks). It is essential to point out that every NMR experiment involving a large number of pulses (e. g. due to the repeating building blocks) is likely to be sensitive to hardware restrictions and small miscalibrations of the duration of the applied pulses. To attenuate the unwanted effects of miscalibrations, Meiboom and Gill modified the previously used Carr–Purcell sequence [171] by changing the phase of the applied 180° pulses from x to y [172]. This procedure can be used to measure T2 relaxation times of any type of nuclei. For instance, in the case of 13C, all pulses and acquisitions are applied on 13C channel, while broadband proton decoupling is applied during all pulse sequences. It works analogically for different NMR-active nuclei [173]."}