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PMC:7594251 / 21395-23877 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T47161 1808-1813 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T51661 1895-1900 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T25681 1905-1910 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T23891 2436-2441 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 1808-1813 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T7 1895-1900 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T8 1905-1910 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T9 2436-2441 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T17528 210-211 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92439 245-246 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T83859 277-278 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91246 305-306 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69709 327-329 http://purl.obolibrary.org/obo/CLO_0050160 denotes t2
T91898 414-416 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T92124 509-511 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T26137 559-560 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T63635 596-598 http://purl.obolibrary.org/obo/CLO_0003401 denotes FT
T78725 1453-1454 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76502 1465-1468 http://purl.obolibrary.org/obo/CLO_0054061 denotes 132
T42866 1808-1813 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T98943 1808-1813 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T84919 2159-2161 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T56516 2261-2262 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86496 2436-2441 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T59085 2436-2441 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T189 115-121 Chemical denotes nuclei http://purl.obolibrary.org/obo/CHEBI_33252
T190 129-131 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T191 132-134 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T192 585-594 Chemical denotes Transform http://purl.obolibrary.org/obo/CHEBI_133305
T193 596-598 Chemical denotes FT http://purl.obolibrary.org/obo/CHEBI_73636
T194 655-661 Chemical denotes proton http://purl.obolibrary.org/obo/CHEBI_24636
T195 663-665 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T196 670-676 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T198 693-699 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T200 841-843 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T201 1067-1073 Chemical denotes nuclei http://purl.obolibrary.org/obo/CHEBI_33252
T202 1150-1155 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T203 1227-1236 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T204 1249-1258 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T205 1262-1270 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T206 1455-1463 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T207 1712-1716 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T208 1745-1753 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T209 1950-1952 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T210 1963-1965 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T211 1982-1984 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T212 1985-1987 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T213 1998-2000 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T214 2172-2183 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T215 2193-2200 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T216 2202-2214 Chemical denotes nicotinamide http://purl.obolibrary.org/obo/CHEBI_17154
T217 2216-2224 Chemical denotes glycerol http://purl.obolibrary.org/obo/CHEBI_17754
T218 2229-2236 Chemical denotes formate http://purl.obolibrary.org/obo/CHEBI_15740|http://purl.obolibrary.org/obo/CHEBI_52343

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
282 1825-1829 Species denotes rats Tax:10116
283 2066-2070 Species denotes rats Tax:10116
284 129-131 Chemical denotes 1H
285 132-134 Chemical denotes 1H
286 663-665 Chemical denotes 1H
287 670-676 Chemical denotes carbon MESH:D002244
288 693-699 Chemical denotes carbon MESH:D002244
289 1950-1952 Chemical denotes 1H
290 1963-1965 Chemical denotes 1H
291 1982-1984 Chemical denotes 1H
292 1985-1987 Chemical denotes 1H
293 1998-2000 Chemical denotes 1H
294 2001-2004 Chemical denotes 13C MESH:C000615229
295 2193-2200 Chemical denotes lactate MESH:D019344
296 2202-2214 Chemical denotes nicotinamide MESH:D009536
297 2216-2224 Chemical denotes glycerol MESH:D005990
298 2229-2236 Chemical denotes formate MESH:C030544
299 1808-1824 Disease denotes blood deficiency MESH:D007022

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T44461 2288-2298 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T154 0-77 Sentence denotes COSY is one of the simplest and most frequently used 2D NMR experiment [123].
T155 78-178 Sentence denotes It shows the homonuclear coupling of nuclei (i.e., 1H-1H) separated by up to several covalent bonds.
T156 179-382 Sentence denotes The pulse sequence consists of a 90° excitation pulse followed by a specific evolution time (t1), a second pulse, and finally a measurement period (t2, not to be confused with relaxation rates or times).
T157 383-558 Sentence denotes The second pulse can be 90° or 45° or 135°, depending upon the specific requirements, and respectively yield COSY [124], COSY-45 or COSY-135 functionality (see [125,126,127]).
T158 559-727 Sentence denotes A two-dimensional Fourier Transform (FT) yields the final spectra and shows the frequencies for proton (1H) or carbon (in the case of carbon detection) along both axes.
T159 728-947 Sentence denotes There are two types of peaks; (I) Diagonal peaks, which represent the peaks of the conventional 1D spectra, and (II) cross-peaks, which have different values in the two frequency axes and are therefore off the diagonal.
T160 948-1117 Sentence denotes These off diagonal cross-peaks are the most important pieces of information as they mark correlations between pairs of nuclei due to through bond magnetization transfer.
T161 1118-1277 Sentence denotes This helps in identifying which atoms are connected [128], critical for structural elucidation of both known molecules and unknown molecules in solution [129].
T162 1278-1470 Sentence denotes By implementing phase-cycling [130,131], it is also possible to distinguish different types of coupling and yields further helpful information about the chemical structure of a molecule [132].
T163 1471-1564 Sentence denotes As an example, the use of the COSY experiment was presented in the work of Zheng et al. [88].
T164 1565-1776 Sentence denotes The main goal of their work was to investigate potential biological differences and compare the pharmacological effects between Danggui (an herbal drug used in traditional Chinese medicine) and European Danggui.
T165 1777-1911 Sentence denotes For that, Zheng et al. treated blood deficiency rats with Danggui and European Danggui and collected samples of their serum and urine.
T166 1912-2071 Sentence denotes The samples were later measured using 1H-CPMG-NMR, 1H-NOESYPRESAT-1D, 1H,1H-COSY, and 1H,13C-HSQC, and then compared to equivalent spectra from untreated rats.
T167 2072-2308 Sentence denotes The results showed that exposure to Danggui and European Danggui altered the levels of 18 different metabolites, such as lactate, nicotinamide, glycerol and formate, which were involved in a total of seven different metabolism pathways.
T168 2309-2482 Sentence denotes Additionally, it was proven that Danggui and European Danggui have different chemical compositions, with Danggui having better blood-enriching effects than European Danggui.