PMC:7594251 / 124548-124840 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T110","span":{"begin":28,"end":33},"obj":"Body_part"},{"id":"T111","span":{"begin":106,"end":112},"obj":"Body_part"},{"id":"T112","span":{"begin":114,"end":119},"obj":"Body_part"},{"id":"T113","span":{"begin":153,"end":157},"obj":"Body_part"},{"id":"T114","span":{"begin":206,"end":211},"obj":"Body_part"},{"id":"T115","span":{"begin":213,"end":218},"obj":"Body_part"}],"attributes":[{"id":"A110","pred":"fma_id","subj":"T110","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A111","pred":"fma_id","subj":"T111","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A112","pred":"fma_id","subj":"T112","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A113","pred":"fma_id","subj":"T113","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A114","pred":"fma_id","subj":"T114","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A115","pred":"fma_id","subj":"T115","obj":"http://purl.org/sig/ont/fma/fma67264"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T42","span":{"begin":106,"end":112},"obj":"Body_part"}],"attributes":[{"id":"A42","pred":"uberon_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T133","span":{"begin":61,"end":75},"obj":"Disease"},{"id":"T134","span":{"begin":69,"end":75},"obj":"Disease"}],"attributes":[{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0008170"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T215","span":{"begin":48,"end":53},"obj":"http://purl.obolibrary.org/obo/CLO_0001571"},{"id":"T216","span":{"begin":48,"end":53},"obj":"http://purl.obolibrary.org/obo/CLO_0051994"},{"id":"T217","span":{"begin":55,"end":60},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T218","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0001230"},{"id":"T219","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0037237"},{"id":"T220","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0050903"},{"id":"T221","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0054249"},{"id":"T222","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0054250"},{"id":"T223","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0054251"},{"id":"T224","span":{"begin":85,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0054252"},{"id":"T225","span":{"begin":90,"end":95},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T226","span":{"begin":96,"end":112},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T227","span":{"begin":114,"end":119},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T228","span":{"begin":153,"end":163},"obj":"http://purl.obolibrary.org/obo/CLO_0000031"},{"id":"T229","span":{"begin":199,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0001571"},{"id":"T230","span":{"begin":199,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0051994"},{"id":"T231","span":{"begin":206,"end":211},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T9566","span":{"begin":28,"end":33},"obj":"Chemical"},{"id":"T45246","span":{"begin":135,"end":138},"obj":"Chemical"},{"id":"T83737","span":{"begin":179,"end":188},"obj":"Chemical"},{"id":"T91790","span":{"begin":213,"end":218},"obj":"Chemical"}],"attributes":[{"id":"A15682","pred":"chebi_id","subj":"T9566","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A57454","pred":"chebi_id","subj":"T45246","obj":"http://purl.obolibrary.org/obo/CHEBI_16856"},{"id":"A90318","pred":"chebi_id","subj":"T83737","obj":"http://purl.obolibrary.org/obo/CHEBI_27899"},{"id":"A82054","pred":"chebi_id","subj":"T91790","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2179","span":{"begin":90,"end":95},"obj":"Species"},{"id":"2289","span":{"begin":28,"end":33},"obj":"Chemical"},{"id":"2290","span":{"begin":135,"end":138},"obj":"Chemical"},{"id":"2291","span":{"begin":179,"end":188},"obj":"Chemical"},{"id":"2292","span":{"begin":213,"end":218},"obj":"Chemical"},{"id":"2359","span":{"begin":55,"end":75},"obj":"Disease"},{"id":"2360","span":{"begin":96,"end":112},"obj":"Disease"},{"id":"2380","span":{"begin":48,"end":53},"obj":"CellLine"},{"id":"2381","span":{"begin":81,"end":88},"obj":"CellLine"},{"id":"2382","span":{"begin":168,"end":173},"obj":"CellLine"},{"id":"2383","span":{"begin":199,"end":204},"obj":"CellLine"}],"attributes":[{"id":"A2179","pred":"tao:has_database_id","subj":"2179","obj":"Tax:9606"},{"id":"A2289","pred":"tao:has_database_id","subj":"2289","obj":"MESH:D008055"},{"id":"A2290","pred":"tao:has_database_id","subj":"2290","obj":"MESH:D005978"},{"id":"A2291","pred":"tao:has_database_id","subj":"2291","obj":"MESH:D002945"},{"id":"A2292","pred":"tao:has_database_id","subj":"2292","obj":"MESH:D008055"},{"id":"A2359","pred":"tao:has_database_id","subj":"2359","obj":"MESH:D010051"},{"id":"A2360","pred":"tao:has_database_id","subj":"2360","obj":"MESH:D007674"},{"id":"A2380","pred":"tao:has_database_id","subj":"2380","obj":"CVCL:0134"},{"id":"A2381","pred":"tao:has_database_id","subj":"2381","obj":"CVCL:0045"},{"id":"A2382","pred":"tao:has_database_id","subj":"2382","obj":"CVCL:0134"},{"id":"A2383","pred":"tao:has_database_id","subj":"2383","obj":"CVCL:0134"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T34","span":{"begin":28,"end":44},"obj":"http://purl.obolibrary.org/obo/GO_0006629"},{"id":"T35","span":{"begin":34,"end":44},"obj":"http://purl.obolibrary.org/obo/GO_0008152"},{"id":"T36","span":{"begin":234,"end":247},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T29","span":{"begin":61,"end":75},"obj":"Phenotype"}],"attributes":[{"id":"A29","pred":"hp_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/HP_0100615"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}

{"project":"LitCovid-sentences","denotations":[{"id":"T866","span":{"begin":165,"end":292},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Metallaprism mainly affects lipid metabolism in A2780 (human ovarian cancer) and HEK-293 (human embryonic kidney) cells, and increases GSH levels in all cell lines. In A2780cisR (cisplatin resistant A2780) cells, lipid biogenesis and glycosylation are affected by treatment with metallaprism."}