PMC:7594251 / 103401-103732 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T21","span":{"begin":34,"end":42},"obj":"Body_part"},{"id":"T22","span":{"begin":140,"end":144},"obj":"Body_part"},{"id":"T23","span":{"begin":250,"end":254},"obj":"Body_part"},{"id":"T24","span":{"begin":283,"end":287},"obj":"Body_part"},{"id":"T25","span":{"begin":322,"end":326},"obj":"Body_part"}],"attributes":[{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"The interactions between targets (proteins) and ligands (small molecules) can be analyzed independently of the biological systems by using ‘cell-based’ NMR drug design approaches. Three basic approaches [409] are as follows: (1) Compound-detected in-cell NMR, (2) Target-detected in-cell NMR, and (3) Reporter-detected in-cell NMR."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T30","span":{"begin":140,"end":144},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T31","span":{"begin":250,"end":254},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T32","span":{"begin":283,"end":287},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T33","span":{"begin":322,"end":326},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"The interactions between targets (proteins) and ligands (small molecules) can be analyzed independently of the biological systems by using ‘cell-based’ NMR drug design approaches. Three basic approaches [409] are as follows: (1) Compound-detected in-cell NMR, (2) Target-detected in-cell NMR, and (3) Reporter-detected in-cell NMR."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T50928","span":{"begin":34,"end":42},"obj":"Chemical"},{"id":"T73305","span":{"begin":48,"end":55},"obj":"Chemical"},{"id":"T694","span":{"begin":63,"end":72},"obj":"Chemical"},{"id":"T6431","span":{"begin":156,"end":160},"obj":"Chemical"}],"attributes":[{"id":"A29535","pred":"chebi_id","subj":"T50928","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A60941","pred":"chebi_id","subj":"T73305","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A83521","pred":"chebi_id","subj":"T694","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A31227","pred":"chebi_id","subj":"T6431","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"The interactions between targets (proteins) and ligands (small molecules) can be analyzed independently of the biological systems by using ‘cell-based’ NMR drug design approaches. Three basic approaches [409] are as follows: (1) Compound-detected in-cell NMR, (2) Target-detected in-cell NMR, and (3) Reporter-detected in-cell NMR."}

{"project":"LitCovid-sentences","denotations":[{"id":"T686","span":{"begin":0,"end":179},"obj":"Sentence"},{"id":"T687","span":{"begin":180,"end":331},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The interactions between targets (proteins) and ligands (small molecules) can be analyzed independently of the biological systems by using ‘cell-based’ NMR drug design approaches. Three basic approaches [409] are as follows: (1) Compound-detected in-cell NMR, (2) Target-detected in-cell NMR, and (3) Reporter-detected in-cell NMR."}