PMC:7589163 / 7993-8403 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T48","span":{"begin":348,"end":352},"obj":"Body_part"},{"id":"T49","span":{"begin":358,"end":364},"obj":"Body_part"}],"attributes":[{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma9637"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T20","span":{"begin":358,"end":364},"obj":"Body_part"}],"attributes":[{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T75","span":{"begin":25,"end":26},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T76","span":{"begin":191,"end":196},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T77","span":{"begin":223,"end":224},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T78","span":{"begin":235,"end":244},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T79","span":{"begin":280,"end":290},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T80","span":{"begin":348,"end":352},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T88","span":{"begin":17,"end":26},"obj":"Chemical"},{"id":"T89","span":{"begin":17,"end":24},"obj":"Chemical"},{"id":"T90","span":{"begin":43,"end":66},"obj":"Chemical"},{"id":"T91","span":{"begin":53,"end":66},"obj":"Chemical"},{"id":"T92","span":{"begin":62,"end":66},"obj":"Chemical"},{"id":"T93","span":{"begin":127,"end":135},"obj":"Chemical"},{"id":"T94","span":{"begin":215,"end":224},"obj":"Chemical"},{"id":"T95","span":{"begin":215,"end":222},"obj":"Chemical"}],"attributes":[{"id":"A88","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_12777"},{"id":"A89","pred":"chebi_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_15367"},{"id":"A91","pred":"chebi_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/CHEBI_26536"},{"id":"A92","pred":"chebi_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A93","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_26537"},{"id":"A94","pred":"chebi_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/CHEBI_17336"},{"id":"A95","pred":"chebi_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T22","span":{"begin":103,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T23","span":{"begin":103,"end":116},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T24","span":{"begin":332,"end":338},"obj":"http://purl.obolibrary.org/obo/GO_0007601"},{"id":"T25","span":{"begin":340,"end":352},"obj":"http://purl.obolibrary.org/obo/GO_0016049"},{"id":"T26","span":{"begin":340,"end":346},"obj":"http://purl.obolibrary.org/obo/GO_0040007"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}

{"project":"LitCovid-sentences","denotations":[{"id":"T60","span":{"begin":0,"end":214},"obj":"Sentence"},{"id":"T61","span":{"begin":215,"end":410},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}

{"project":"LitCovid-PubTator","denotations":[{"id":"138","span":{"begin":17,"end":26},"obj":"Chemical"},{"id":"139","span":{"begin":43,"end":66},"obj":"Chemical"},{"id":"140","span":{"begin":215,"end":224},"obj":"Chemical"},{"id":"141","span":{"begin":382,"end":396},"obj":"Disease"}],"attributes":[{"id":"A138","pred":"tao:has_database_id","subj":"138","obj":"MESH:D014801"},{"id":"A139","pred":"tao:has_database_id","subj":"139","obj":"MESH:D014212"},{"id":"A140","pred":"tao:has_database_id","subj":"140","obj":"MESH:D014801"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The functions of vitamin A are mediated by all-trans-retinoic acid, which, by binding specific nuclear transcription factors, (retinoid receptors) regulates the expression of several hundred genes [15,16,17,18,19]. Vitamin A-regulated genes are involved in fundamental biological activities, playing an important role in supporting vision, growth, cell, and tissue differentiation, haematopoiesis and immunity."}