PMC:7589163 / 7229-7992
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T39","span":{"begin":17,"end":19},"obj":"Body_part"},{"id":"T40","span":{"begin":157,"end":162},"obj":"Body_part"},{"id":"T41","span":{"begin":170,"end":174},"obj":"Body_part"},{"id":"T42","span":{"begin":424,"end":452},"obj":"Body_part"},{"id":"T43","span":{"begin":437,"end":452},"obj":"Body_part"},{"id":"T44","span":{"begin":483,"end":493},"obj":"Body_part"},{"id":"T45","span":{"begin":534,"end":539},"obj":"Body_part"},{"id":"T46","span":{"begin":710,"end":717},"obj":"Body_part"},{"id":"T47","span":{"begin":750,"end":757},"obj":"Body_part"}],"attributes":[{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma66592"},{"id":"A40","pred":"fma_id","subj":"T40","obj":"http://purl.org/sig/ont/fma/fma67498"},{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma62100"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma14587"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma7200"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma62122"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma9637"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T15","span":{"begin":157,"end":162},"obj":"Body_part"},{"id":"T16","span":{"begin":170,"end":174},"obj":"Body_part"},{"id":"T17","span":{"begin":437,"end":452},"obj":"Body_part"},{"id":"T18","span":{"begin":443,"end":452},"obj":"Body_part"},{"id":"T19","span":{"begin":534,"end":539},"obj":"Body_part"}],"attributes":[{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0001913"},{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0002108"},{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T62","span":{"begin":24,"end":25},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T63","span":{"begin":26,"end":29},"obj":"http://purl.obolibrary.org/obo/UBERON_0001013"},{"id":"T64","span":{"begin":118,"end":124},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T65","span":{"begin":143,"end":144},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T66","span":{"begin":157,"end":162},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T67","span":{"begin":245,"end":246},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T68","span":{"begin":335,"end":336},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T69","span":{"begin":437,"end":452},"obj":"http://purl.obolibrary.org/obo/UBERON_0002108"},{"id":"T70","span":{"begin":534,"end":539},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T71","span":{"begin":534,"end":539},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T72","span":{"begin":588,"end":589},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T73","span":{"begin":606,"end":607},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T74","span":{"begin":635,"end":636},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T60","span":{"begin":0,"end":7},"obj":"Chemical"},{"id":"T61","span":{"begin":9,"end":16},"obj":"Chemical"},{"id":"T62","span":{"begin":26,"end":45},"obj":"Chemical"},{"id":"T63","span":{"begin":38,"end":45},"obj":"Chemical"},{"id":"T64","span":{"begin":135,"end":144},"obj":"Chemical"},{"id":"T65","span":{"begin":135,"end":142},"obj":"Chemical"},{"id":"T66","span":{"begin":234,"end":246},"obj":"Chemical"},{"id":"T67","span":{"begin":234,"end":244},"obj":"Chemical"},{"id":"T68","span":{"begin":247,"end":258},"obj":"Chemical"},{"id":"T69","span":{"begin":285,"end":292},"obj":"Chemical"},{"id":"T70","span":{"begin":327,"end":336},"obj":"Chemical"},{"id":"T71","span":{"begin":327,"end":334},"obj":"Chemical"},{"id":"T72","span":{"begin":338,"end":345},"obj":"Chemical"},{"id":"T73","span":{"begin":347,"end":354},"obj":"Chemical"},{"id":"T74","span":{"begin":356,"end":369},"obj":"Chemical"},{"id":"T75","span":{"begin":365,"end":369},"obj":"Chemical"},{"id":"T76","span":{"begin":375,"end":388},"obj":"Chemical"},{"id":"T77","span":{"begin":375,"end":382},"obj":"Chemical"},{"id":"T78","span":{"begin":383,"end":388},"obj":"Chemical"},{"id":"T79","span":{"begin":409,"end":416},"obj":"Chemical"},{"id":"T80","span":{"begin":454,"end":461},"obj":"Chemical"},{"id":"T81","span":{"begin":580,"end":589},"obj":"Chemical"},{"id":"T82","span":{"begin":580,"end":587},"obj":"Chemical"},{"id":"T83","span":{"begin":627,"end":636},"obj":"Chemical"},{"id":"T84","span":{"begin":627,"end":634},"obj":"Chemical"},{"id":"T85","span":{"begin":663,"end":670},"obj":"Chemical"},{"id":"T86","span":{"begin":694,"end":701},"obj":"Chemical"},{"id":"T87","span":{"begin":710,"end":717},"obj":"Chemical"}],"attributes":[{"id":"A60","pred":"chebi_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/CHEBI_17336"},{"id":"A61","pred":"chebi_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_24020"},{"id":"A63","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_12777"},{"id":"A65","pred":"chebi_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A66","pred":"chebi_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_67200"},{"id":"A67","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_50188"},{"id":"A68","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_23044"},{"id":"A69","pred":"chebi_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/CHEBI_15035"},{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_12777"},{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A72","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_50211"},{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_15035"},{"id":"A74","pred":"chebi_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/CHEBI_26536"},{"id":"A75","pred":"chebi_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A76","pred":"chebi_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/CHEBI_16179"},{"id":"A77","pred":"chebi_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/CHEBI_26541"},{"id":"A78","pred":"chebi_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_35701"},{"id":"A79","pred":"chebi_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/CHEBI_50211"},{"id":"A80","pred":"chebi_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/CHEBI_17336"},{"id":"A81","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_12777"},{"id":"A82","pred":"chebi_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_12777"},{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_50211"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_50211"},{"id":"A87","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T21","span":{"begin":590,"end":597},"obj":"http://purl.obolibrary.org/obo/GO_0051235"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T55","span":{"begin":0,"end":125},"obj":"Sentence"},{"id":"T56","span":{"begin":126,"end":316},"obj":"Sentence"},{"id":"T57","span":{"begin":317,"end":453},"obj":"Sentence"},{"id":"T58","span":{"begin":454,"end":598},"obj":"Sentence"},{"id":"T59","span":{"begin":599,"end":763},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"117","span":{"begin":694,"end":717},"obj":"Gene"},{"id":"118","span":{"begin":719,"end":722},"obj":"Gene"},{"id":"119","span":{"begin":118,"end":124},"obj":"Species"},{"id":"120","span":{"begin":0,"end":7},"obj":"Chemical"},{"id":"121","span":{"begin":9,"end":19},"obj":"Chemical"},{"id":"122","span":{"begin":135,"end":144},"obj":"Chemical"},{"id":"123","span":{"begin":247,"end":258},"obj":"Chemical"},{"id":"124","span":{"begin":327,"end":336},"obj":"Chemical"},{"id":"125","span":{"begin":338,"end":345},"obj":"Chemical"},{"id":"126","span":{"begin":347,"end":354},"obj":"Chemical"},{"id":"127","span":{"begin":356,"end":369},"obj":"Chemical"},{"id":"128","span":{"begin":375,"end":388},"obj":"Chemical"},{"id":"129","span":{"begin":409,"end":416},"obj":"Chemical"},{"id":"130","span":{"begin":454,"end":461},"obj":"Chemical"},{"id":"131","span":{"begin":580,"end":589},"obj":"Chemical"},{"id":"132","span":{"begin":627,"end":636},"obj":"Chemical"},{"id":"133","span":{"begin":608,"end":625},"obj":"Disease"}],"attributes":[{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"Gene:5950"},{"id":"A118","pred":"tao:has_database_id","subj":"118","obj":"Gene:5950"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"Tax:9606"},{"id":"A120","pred":"tao:has_database_id","subj":"120","obj":"MESH:D014801"},{"id":"A121","pred":"tao:has_database_id","subj":"121","obj":"MESH:D014801"},{"id":"A122","pred":"tao:has_database_id","subj":"122","obj":"MESH:D014801"},{"id":"A123","pred":"tao:has_database_id","subj":"123","obj":"MESH:D002338"},{"id":"A124","pred":"tao:has_database_id","subj":"124","obj":"MESH:D014801"},{"id":"A125","pred":"tao:has_database_id","subj":"125","obj":"MESH:D014801"},{"id":"A126","pred":"tao:has_database_id","subj":"126","obj":"MESH:D012172"},{"id":"A127","pred":"tao:has_database_id","subj":"127","obj":"MESH:D014212"},{"id":"A129","pred":"tao:has_database_id","subj":"129","obj":"MESH:D014801"},{"id":"A130","pred":"tao:has_database_id","subj":"130","obj":"MESH:D014801"},{"id":"A131","pred":"tao:has_database_id","subj":"131","obj":"MESH:D014801"},{"id":"A132","pred":"tao:has_database_id","subj":"132","obj":"MESH:D014801"},{"id":"A133","pred":"tao:has_database_id","subj":"133","obj":"MESH:D013226"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Retinol (vitamin A1) is a fat-soluble vitamin and an obligatory dietary factor since it is not synthesized de novo by humans. The main vitamin A sources are organ meats, milk, cheese; in green vegetables and yellow fruits are present provitamin A carotenoids, which must be cleaved to retinal before absorption [15]. Preformed vitamin A (retinol, retinal, retinoic acid, and retinyl ester) is hydrolysed into retinol in the lumen of the small intestine. Retinol is esterified in the enterocyte and packaged into chylomicrons, and the liver represents the main site of chylomicron vitamin A storage. During a deficiency status, vitamin A stores are mobilized, and retinol circulate bound to the retinol-binding protein (RBP) and is utilized by target tissues [15]."}