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PMC:7589163 / 46512-56285 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T215 11-22 Body_part denotes Fatty Acids http://purl.org/sig/ont/fma/fma82738
T216 62-73 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T217 106-117 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T218 222-232 Body_part denotes fatty acid http://purl.org/sig/ont/fma/fma82738
T219 302-312 Body_part denotes fatty acid http://purl.org/sig/ont/fma/fma82738
T220 457-468 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T221 897-908 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T222 1253-1264 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T223 1413-1424 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T224 1453-1457 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T225 1479-1492 Body_part denotes phospholipids http://purl.org/sig/ont/fma/fma82779
T226 1521-1535 Body_part denotes cell membranes http://purl.org/sig/ont/fma/fma63841
T227 1521-1525 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T228 1578-1582 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T229 1699-1716 Body_part denotes endocrine systems http://purl.org/sig/ont/fma/fma9668
T230 2232-2242 Body_part denotes fatty acid http://purl.org/sig/ont/fma/fma82738
T231 2377-2381 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T232 2513-2524 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T233 2575-2585 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T234 2614-2624 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T235 2743-2760 Body_part denotes tissue neutrophil http://purl.org/sig/ont/fma/fma0326465
T236 2787-2793 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T237 2831-2837 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T238 2909-2920 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T239 2972-2977 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T240 2990-3001 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T241 3053-3073 Body_part denotes natural killer cells http://purl.org/sig/ont/fma/fma63147
T242 3068-3073 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T243 3085-3096 Body_part denotes granulocyte http://purl.org/sig/ont/fma/fma62854
T244 3148-3176 Body_part denotes polymorphonuclear leukocytes http://purl.org/sig/ont/fma/fma62860
T245 3253-3261 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T246 3389-3394 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T247 3431-3440 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T248 3512-3523 Body_part denotes Fatty Acids http://purl.org/sig/ont/fma/fma82738
T249 3531-3537 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T250 3542-3547 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T251 3548-3558 Body_part denotes fatty acid http://purl.org/sig/ont/fma/fma82738
T252 3762-3767 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T253 3768-3780 Body_part denotes phospholipid http://purl.org/sig/ont/fma/fma82779
T254 3781-3792 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T255 3854-3859 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T256 3860-3872 Body_part denotes phospholipid http://purl.org/sig/ont/fma/fma82779
T257 3956-3967 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T258 3968-3979 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T259 4082-4097 Body_part denotes red blood cells http://purl.org/sig/ont/fma/fma62845
T260 4092-4097 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T261 4144-4155 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T262 4156-4167 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T263 4262-4273 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T264 4274-4285 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T265 4406-4411 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T266 4740-4751 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T267 4756-4759 Body_part denotes gut http://purl.org/sig/ont/fma/fma7199
T268 4971-4974 Body_part denotes EAR http://purl.org/sig/ont/fma/fma52780
T269 5474-5485 Body_part denotes Fatty Acids http://purl.org/sig/ont/fma/fma82738
T270 5558-5569 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T271 5664-5681 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T272 5781-5792 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T273 5891-5895 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T274 6050-6061 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T275 6122-6139 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T276 6476-6489 Body_part denotes bronchiolitis http://purl.org/sig/ont/fma/fma76497
T277 6679-6702 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662
T278 7208-7213 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T279 7329-7352 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662
T280 7497-7520 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T281 8236-8244 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T282 8387-8398 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T283 8468-8474 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T284 8475-8483 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T285 8673-8696 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T286 8875-8886 Body_part denotes fatty acids http://purl.org/sig/ont/fma/fma82738
T287 8984-8988 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T288 9252-9257 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T289 9613-9617 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T85 1699-1716 Body_part denotes endocrine systems http://purl.obolibrary.org/obo/UBERON_0000949
T86 2743-2749 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T87 2787-2793 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T88 2831-2837 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T89 3542-3547 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T90 3762-3767 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T91 3854-3859 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T92 4086-4091 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T93 5664-5681 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T94 5891-5895 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T95 6122-6139 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T96 6679-6702 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T97 6685-6702 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T98 7208-7213 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T99 7329-7352 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T100 7335-7352 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T101 7497-7520 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T102 7503-7520 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T103 8673-8696 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T104 8679-8696 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T105 8984-8988 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T106 9252-9257 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T107 9613-9617 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T185 1941-1953 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T186 2485-2497 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T187 2575-2595 Disease denotes neutrophil migration http://purl.obolibrary.org/obo/MONDO_0008091
T188 2638-2650 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T189 2852-2864 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T190 3478-3490 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T191 4619-4631 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T192 5510-5525 Disease denotes Viral Infection http://purl.obolibrary.org/obo/MONDO_0005108
T193 5516-5525 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T194 5611-5623 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T195 5635-5645 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T196 5813-5835 Disease denotes respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T197 5885-5902 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T199 5896-5902 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T200 5907-5942 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T201 5913-5942 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T202 5944-5948 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T203 6122-6150 Disease denotes respiratory tract infections http://purl.obolibrary.org/obo/MONDO_0024355
T204 6166-6172 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T205 6476-6489 Disease denotes bronchiolitis http://purl.obolibrary.org/obo/MONDO_0002465
T206 6917-6923 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T207 7311-7321 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T208 7497-7531 Disease denotes upper respiratory tract infections http://purl.obolibrary.org/obo/MONDO_0024355
T209 8023-8035 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T210 8073-8081 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T211 8257-8275 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T212 8280-8284 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T213 8978-8995 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T215 8989-8995 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T216 9096-9108 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T217 9349-9353 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T218 9618-9624 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T219 9654-9666 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T469 78-79 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T470 159-160 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T471 254-256 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T472 328-330 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T473 403-405 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T474 434-436 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T475 612-617 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T476 618-626 http://purl.obolibrary.org/obo/OBI_0100026 denotes organism
T477 618-626 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organism
T478 643-650 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T479 803-805 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T480 1026-1027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T481 1112-1115 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T482 1190-1196 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T483 1372-1376 http://purl.obolibrary.org/obo/NCBITaxon_117565 denotes fish
T484 1378-1382 http://purl.obolibrary.org/obo/NCBITaxon_117565 denotes fish
T485 1521-1525 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T486 1526-1535 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T487 1699-1716 http://purl.obolibrary.org/obo/UBERON_0000949 denotes endocrine systems
T488 1699-1716 http://www.ebi.ac.uk/efo/EFO_0002969 denotes endocrine systems
T489 2377-2381 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T490 2439-2440 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T491 2694-2695 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T492 2761-2771 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T493 2972-2977 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T494 3053-3073 http://purl.obolibrary.org/obo/CL_0000623 denotes natural killer cells
T495 3274-3275 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T496 3377-3386 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T497 3387-3394 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T498 3531-3537 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T499 3803-3804 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T500 3896-3899 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3–4
T501 3956-3967 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T502 4082-4097 http://purl.obolibrary.org/obo/CL_0000232 denotes red blood cells
T503 4098-4107 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T504 4122-4123 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T505 4144-4155 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T506 4254-4257 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3–5
T507 4262-4273 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T508 4318-4322 http://purl.obolibrary.org/obo/NCBITaxon_117565 denotes fish
T509 4648-4649 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T510 4694-4697 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T511 4714-4715 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T512 4756-4759 http://purl.obolibrary.org/obo/UBERON_0001007 denotes gut
T513 4756-4759 http://purl.obolibrary.org/obo/UBERON_0001555 denotes gut
T514 4756-4759 http://www.ebi.ac.uk/efo/EFO_0000834 denotes gut
T515 4971-4974 http://www.ebi.ac.uk/efo/EFO_0000826 denotes EAR
T516 5372-5374 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T517 5575-5576 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T518 5891-5895 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T519 5891-5895 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T520 6283-6287 http://purl.obolibrary.org/obo/CLO_0001757 denotes at 1
T521 6358-6359 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T522 6391-6396 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T523 6454-6455 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T524 6476-6489 http://purl.obolibrary.org/obo/UBERON_0002186 denotes bronchiolitis
T525 6679-6702 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T526 6725-6727 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T527 6778-6779 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T528 6847-6848 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T529 7208-7213 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T530 7208-7213 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T531 7293-7294 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T532 7329-7352 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T533 7559-7560 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T534 8037-8040 http://purl.obolibrary.org/obo/CLO_0001195 denotes 219
T535 8046-8049 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T536 8100-8101 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T537 8468-8474 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T538 8520-8521 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T539 8707-8708 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T540 8984-8988 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T541 8984-8988 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T542 9054-9055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T543 9162-9163 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T544 9223-9224 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T545 9252-9257 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T546 9252-9257 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T547 9445-9446 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T548 9522-9528 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T549 9564-9565 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T550 9613-9617 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T551 9613-9617 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T648 62-73 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T649 68-73 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T650 90-117 Chemical denotes polyunsaturated fatty acids http://purl.obolibrary.org/obo/CHEBI_26208
T651 106-117 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T652 112-117 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T653 119-124 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T654 188-199 Chemical denotes carbon atom http://purl.obolibrary.org/obo/CHEBI_27594
T655 188-194 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_33415
T656 195-199 Chemical denotes atom http://purl.obolibrary.org/obo/CHEBI_33250
T657 214-232 Chemical denotes omega-3 fatty acid http://purl.obolibrary.org/obo/CHEBI_25681
T658 222-232 Chemical denotes fatty acid http://purl.obolibrary.org/obo/CHEBI_35366
T659 228-232 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T660 238-252 Chemical denotes linolenic acid http://purl.obolibrary.org/obo/CHEBI_25048|http://purl.obolibrary.org/obo/CHEBI_27432
T662 248-252 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T663 294-312 Chemical denotes omega-6 fatty acid http://purl.obolibrary.org/obo/CHEBI_36009
T664 302-312 Chemical denotes fatty acid http://purl.obolibrary.org/obo/CHEBI_35366
T665 308-312 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T666 313-326 Chemical denotes linoleic acid http://purl.obolibrary.org/obo/CHEBI_17351
T667 322-326 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T668 388-401 Chemical denotes Linoleic acid http://purl.obolibrary.org/obo/CHEBI_17351
T669 397-401 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T670 418-432 Chemical denotes linolenic acid http://purl.obolibrary.org/obo/CHEBI_25048|http://purl.obolibrary.org/obo/CHEBI_27432
T672 428-432 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T673 447-468 Chemical denotes essential fatty acids http://purl.obolibrary.org/obo/CHEBI_59549
T674 457-468 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T675 463-468 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T676 470-474 Chemical denotes EFAs http://purl.obolibrary.org/obo/CHEBI_59549
T677 668-682 Chemical denotes linolenic acid http://purl.obolibrary.org/obo/CHEBI_25048|http://purl.obolibrary.org/obo/CHEBI_27432
T679 678-682 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T680 731-752 Chemical denotes eicosapentaenoic acid http://purl.obolibrary.org/obo/CHEBI_36006
T681 748-752 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T682 772-775 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T683 781-801 Chemical denotes docosahexaenoic acid http://purl.obolibrary.org/obo/CHEBI_36005
T684 797-801 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T685 821-824 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T689 889-908 Chemical denotes omega-6 fatty acids http://purl.obolibrary.org/obo/CHEBI_36009
T690 897-908 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T691 903-908 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T692 972-988 Chemical denotes arachidonic acid http://purl.obolibrary.org/obo/CHEBI_15843
T693 984-988 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T694 1008-1022 Chemical denotes linolenic acid http://purl.obolibrary.org/obo/CHEBI_25048|http://purl.obolibrary.org/obo/CHEBI_27432
T696 1018-1022 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T697 1040-1049 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T698 1053-1066 Chemical denotes linoleic acid http://purl.obolibrary.org/obo/CHEBI_17351
T699 1062-1066 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T700 1157-1160 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T701 1165-1168 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T705 1253-1264 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T706 1259-1264 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T707 1304-1318 Chemical denotes linolenic acid http://purl.obolibrary.org/obo/CHEBI_25048|http://purl.obolibrary.org/obo/CHEBI_27432
T709 1314-1318 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T710 1345-1348 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T714 1353-1356 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T715 1413-1424 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T716 1419-1424 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T717 1479-1492 Chemical denotes phospholipids http://purl.obolibrary.org/obo/CHEBI_16247
T718 1604-1615 Chemical denotes eicosanoids http://purl.obolibrary.org/obo/CHEBI_23899
T719 1699-1708 Chemical denotes endocrine http://purl.obolibrary.org/obo/CHEBI_24621
T720 1757-1768 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T721 1819-1824 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T722 1882-1891 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T723 1961-1996 Chemical denotes specialized pro-resolving mediators http://purl.obolibrary.org/obo/CHEBI_140399
T724 1998-2002 Chemical denotes SPMs http://purl.obolibrary.org/obo/CHEBI_140399
T725 2021-2030 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T726 2049-2073 Chemical denotes immunosuppressive agents http://purl.obolibrary.org/obo/CHEBI_35705
T727 2155-2168 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T728 2206-2210 Chemical denotes SPMs http://purl.obolibrary.org/obo/CHEBI_140399
T729 2224-2242 Chemical denotes omega-3 fatty acid http://purl.obolibrary.org/obo/CHEBI_25681
T730 2232-2242 Chemical denotes fatty acid http://purl.obolibrary.org/obo/CHEBI_35366
T731 2238-2242 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T732 2244-2247 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T733 2252-2255 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T737 2275-2284 Chemical denotes resolvins http://purl.obolibrary.org/obo/CHEBI_132120
T47450 2513-2524 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T57233 2519-2524 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T26611 2525-2536 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T55451 2537-2546 Chemical denotes resolvins http://purl.obolibrary.org/obo/CHEBI_132120
T90199 2680-2684 Chemical denotes SPMs http://purl.obolibrary.org/obo/CHEBI_140399
T19336 3038-3042 Chemical denotes SPMs http://purl.obolibrary.org/obo/CHEBI_140399
T1204 3230-3234 Chemical denotes SPMs http://purl.obolibrary.org/obo/CHEBI_140399
T91510 3548-3558 Chemical denotes fatty acid http://purl.obolibrary.org/obo/CHEBI_35366
T44186 3554-3558 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T36758 3768-3780 Chemical denotes phospholipid http://purl.obolibrary.org/obo/CHEBI_16247
T41209 3781-3792 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T81819 3787-3792 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T13 3860-3872 Chemical denotes phospholipid http://purl.obolibrary.org/obo/CHEBI_16247
T62072 3873-3876 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T55598 3882-3885 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T34598 3968-3979 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T87476 3974-3979 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T97927 4066-4069 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T28667 4075-4078 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T45009 4156-4167 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T56630 4162-4167 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T62907 4209-4212 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T64444 4217-4220 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T26023 4232-4235 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T77261 4240-4243 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T38 4274-4285 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T39 4280-4285 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T6320 4406-4411 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T77558 4420-4431 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T70174 4440-4448 Chemical denotes resolvin http://purl.obolibrary.org/obo/CHEBI_132120
T96319 4476-4481 Chemical denotes epoxy http://purl.obolibrary.org/obo/CHEBI_30721
T52947 4482-4503 Chemical denotes eicosatetraenoic acid http://purl.obolibrary.org/obo/CHEBI_36033
T45596 4499-4503 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T81633 4530-4537 Chemical denotes hydroxy http://purl.obolibrary.org/obo/CHEBI_43176
T12386 4545-4562 Chemical denotes octadecenoic acid http://purl.obolibrary.org/obo/CHEBI_25634
T59085 4558-4562 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T80837 4732-4751 Chemical denotes omega-3 fatty acids http://purl.obolibrary.org/obo/CHEBI_25681
T81997 4740-4751 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T15438 4746-4751 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T89162 4814-4824 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T71268 5072-5074 Chemical denotes AI http://purl.obolibrary.org/obo/CHEBI_73805|http://purl.obolibrary.org/obo/CHEBI_74007|http://purl.obolibrary.org/obo/CHEBI_74088
T37041 5101-5122 Chemical denotes eicosapentaenoic acid http://purl.obolibrary.org/obo/CHEBI_36006
T43880 5118-5122 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T23283 5128-5148 Chemical denotes docosahexaenoic acid http://purl.obolibrary.org/obo/CHEBI_36005
T67863 5144-5148 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T20937 5326-5346 Chemical denotes docosahexaenoic acid http://purl.obolibrary.org/obo/CHEBI_36005
T79906 5342-5346 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T97771 5386-5388 Chemical denotes AI http://purl.obolibrary.org/obo/CHEBI_73805|http://purl.obolibrary.org/obo/CHEBI_74007|http://purl.obolibrary.org/obo/CHEBI_74088
T14927 5550-5569 Chemical denotes omega-3 fatty acids http://purl.obolibrary.org/obo/CHEBI_25681
T1949 5558-5569 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T92440 5564-5569 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T48064 5773-5792 Chemical denotes omega-3 fatty acids http://purl.obolibrary.org/obo/CHEBI_25681
T85959 5781-5792 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T33460 5787-5792 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T58954 6042-6061 Chemical denotes omega-3 fatty acids http://purl.obolibrary.org/obo/CHEBI_25681
T5515 6050-6061 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T92728 6056-6061 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T72908 6200-6203 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T8053 6391-6396 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T90045 6634-6637 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T81148 7057-7061 Chemical denotes PUFA http://purl.obolibrary.org/obo/CHEBI_26208|http://purl.obolibrary.org/obo/CHEBI_76567
T36825 7063-7066 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T16119 7067-7070 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T91570 7196-7199 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T48796 7204-7207 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T75459 7660-7664 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T92639 7689-7693 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T21492 7809-7812 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T24852 7813-7816 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T3102 7921-7924 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T35584 7930-7933 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T107 7962-7966 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T33193 8379-8398 Chemical denotes omega-3 fatty acids http://purl.obolibrary.org/obo/CHEBI_25681
T109 8387-8398 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T8479 8393-8398 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T9556 8399-8402 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T58343 8407-8410 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T92876 8592-8597 Chemical denotes PUFAs http://purl.obolibrary.org/obo/CHEBI_26208
T6089 8796-8801 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T4091 8867-8886 Chemical denotes omega-3 fatty acids http://purl.obolibrary.org/obo/CHEBI_25681
T2588 8875-8886 Chemical denotes fatty acids http://purl.obolibrary.org/obo/CHEBI_35366
T95901 8881-8886 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T5459 9388-9400 Chemical denotes antioxidants http://purl.obolibrary.org/obo/CHEBI_22586
T6801 9413-9416 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T71178 9421-9424 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T60144 9585-9588 Chemical denotes EPA http://purl.obolibrary.org/obo/CHEBI_28364
T90975 9593-9596 Chemical denotes DHA http://purl.obolibrary.org/obo/CHEBI_16016|http://purl.obolibrary.org/obo/CHEBI_28125|http://purl.obolibrary.org/obo/CHEBI_28689|http://purl.obolibrary.org/obo/CHEBI_36005
T2274 9699-9703 Chemical denotes SPMs http://purl.obolibrary.org/obo/CHEBI_140399

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T116 29-39 http://purl.obolibrary.org/obo/GO_0008152 denotes Metabolism
T117 1053-1077 http://purl.obolibrary.org/obo/GO_0043651 denotes linoleic acid metabolism
T118 1067-1077 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T119 1941-1953 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T120 2105-2126 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T121 2485-2497 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T122 2564-2595 http://purl.obolibrary.org/obo/GO_1902623 denotes inhibiting neutrophil migration
T123 2575-2595 http://purl.obolibrary.org/obo/GO_1990266 denotes neutrophil migration
T124 2638-2650 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T125 2750-2771 http://purl.obolibrary.org/obo/GO_0042119 denotes neutrophil activation
T126 2852-2864 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T127 2936-2958 http://purl.obolibrary.org/obo/GO_0050766 denotes stimulate phagocytosis
T128 2946-2958 http://purl.obolibrary.org/obo/GO_0006909 denotes phagocytosis
T129 3097-3106 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T130 3097-3106 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T131 3188-3214 http://purl.obolibrary.org/obo/GO_0050728 denotes anti-inflammatory response
T132 3193-3214 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T133 3253-3272 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T134 3401-3413 http://purl.obolibrary.org/obo/GO_0051235 denotes sequestering
T135 3478-3490 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T136 4605-4615 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T137 4619-4631 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T138 5510-5525 http://purl.obolibrary.org/obo/GO_0016032 denotes Viral Infection
T139 5611-5623 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T140 8023-8035 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T141 8435-8456 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T142 8475-8494 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T143 8915-8936 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T144 9096-9108 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T145 9654-9666 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T94 5813-5835 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T95 5885-5902 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T96 5913-5933 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T97 6122-6150 Phenotype denotes respiratory tract infections http://purl.obolibrary.org/obo/HP_0011947
T98 6152-6160 Phenotype denotes wheezing http://purl.obolibrary.org/obo/HP_0030828
T99 6166-6172 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T100 6476-6489 Phenotype denotes bronchiolitis http://purl.obolibrary.org/obo/HP_0011950
T101 6917-6923 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T102 7497-7531 Phenotype denotes upper respiratory tract infections http://purl.obolibrary.org/obo/HP_0002788
T103 7975-7991 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T104 8236-8250 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T105 8978-8995 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T275 0-2 Sentence denotes 6.
T276 3-22 Sentence denotes Omega-3 Fatty Acids
T277 24-28 Sentence denotes 6.1.
T278 29-53 Sentence denotes Metabolism and Functions
T279 54-200 Sentence denotes Omega-3 fatty acids are a family of polyunsaturated fatty acids (PUFAs) characterized by the presence of a double bond at the omega−3 carbon atom.
T280 201-387 Sentence denotes The simplest omega-3 fatty acid is α-linolenic acid (18:3n-3), which is synthesized from the omega-6 fatty acid linoleic acid (18:2n-6) by desaturation, catalysed by delta-15 desaturase.
T281 388-526 Sentence denotes Linoleic acid (18:2n-6) and α-linolenic acid (18:3n-3) are essential fatty acids (EFAs), meaning that they must be obtained from the diet.
T282 527-633 Sentence denotes Indeed, they are synthesized by plants and cannot be synthesized sufficiently by the human organism [190].
T283 634-826 Sentence denotes However, animals can metabolize α-linolenic acid by further desaturation and elongation to yield eicosapentaenoic acid (20:5n-3; known as EPA) and docosahexaenoic acid (22:6n-3; known as DHA).
T284 827-989 Sentence denotes It is important to note that the same enzymes are employed by omega-6 fatty acids for their metabolic pathways, which leads to the production of arachidonic acid.
T285 990-1099 Sentence denotes This means that α-linolenic acid is a competitive inhibitor of linoleic acid metabolism and vice versa [191].
T286 1100-1235 Sentence denotes However, it has been demonstrated that the conversion to EPA and DHA is generally poor in humans, with reported rates of less than 15%.
T287 1236-1298 Sentence denotes Therefore, these fatty acids must be supplied with food [192].
T288 1299-1404 Sentence denotes Alfa-linolenic acid is present in plant oils, DHA and EPA are present in fish, fish oils, and krill oils.
T289 1405-1536 Sentence denotes Omega-3 fatty acids play important roles in the body as components of the phospholipids that form the structures of cell membranes.
T290 1537-1723 Sentence denotes Furthermore, they provide energy for the body and are used to form eicosanoids, exercising several functions in the body’s cardiovascular, pulmonary, immune, and endocrine systems [189].
T291 1724-1818 Sentence denotes Both omega-3 and omega-6-derived metabolites have important immune-regulatory functions [193].
T292 1819-2014 Sentence denotes PUFAs represent substrates for the enzymatically production of molecules that play an important role in the resolution of inflammation, named specialized pro-resolving mediators (SPMs) [194,195].
T293 2015-2205 Sentence denotes These molecules are distinct from immunosuppressive agents because they contribute to the inflammatory response resolution but also display antimicrobial action promoting host defence [196].
T294 2206-2311 Sentence denotes SPMs derived from omega-3 fatty acid (EPA and DHA) are classified as resolvins, protectins, and maresins.
T295 2312-2504 Sentence denotes These pro-resolving mediators are important in supporting immune cell functions to neutralize and eliminate pathogens and play a crucial role in promoting the resolution of inflammation [197].
T296 2505-2666 Sentence denotes Omega-3 fatty acids metabolites resolvins are effective in inhibiting neutrophil migration, reducing further neutrophil entry in the inflammation site [198,199].
T297 2667-2811 Sentence denotes Furthermore, SPMs exercise a potent anti-inflammatory action, also reducing tissue neutrophil activation and preventing tissue damage [197,200].
T298 2812-3024 Sentence denotes In order to obtain tissue resolution of inflammation, it is essential the clearance of apoptotic neutrophils and protectins stimulate phagocytosis of apoptotic cells mediated by macrophages [201,202,203,204,205].
T299 3025-3183 Sentence denotes Furthermore, SPMs stimulate natural killer cells to trigger granulocyte apoptosis, accelerating the clearance of apoptotic polymorphonuclear leukocytes [206].
T300 3184-3273 Sentence denotes The anti-inflammatory response is promoted by SPMs also by dampening cytokine production.
T301 3274-3497 Sentence denotes A study of Ariel et al. suggests that pro-resolving mediators upregulate CCR5 expression on apoptotic, activated T cells, thus sequestering pro-inflammatory cytokines, and promoting the resolution of the inflammation [207].
T302 3499-3503 Sentence denotes 6.2.
T303 3504-3530 Sentence denotes Omega-3 Fatty Acids Status
T304 3531-3680 Sentence denotes Plasma and serum fatty acid values can vary significantly based on an individual’s most recent meal, so they do not reflect long-term dietary intake.
T305 3681-3793 Sentence denotes However, omega-3 status can be valued by calculating the percentage of the total serum phospholipid fatty acids.
T306 3794-3907 Sentence denotes Although a normal range is not established, mean values for serum phospholipid EPA plus DHA are about 3–4% [206].
T307 3908-3980 Sentence denotes Omega-3 status could also be assessed analysing erythrocyte fatty acids.
T308 3981-4231 Sentence denotes Harris and von Schacky proposed the “omega-3 index”, which represents the content of EPA plus DHA in red blood cells membranes, expressed as a percentage of total erythrocyte fatty acids, and reflects better long-term intake of EPA and DHA [207,208].
T309 4232-4337 Sentence denotes EPA and DHA are about 3–5% of erythrocyte fatty acids in Western populations with low fish intakes [209].
T310 4338-4690 Sentence denotes Moreover, the recent discovery of novel dietary omega-3 and omega-6 lipid-derived metabolites-such as resolvin, protectin, maresin, 17,18-epoxy-eicosatetraenoic acid, and microbe-dependent 10-hydroxy-cis-12-octadecenoic acid, and their potent biologic effects on the regulation of inflammation, have initiated a new era of nutritional immunology [210].
T311 4691-4831 Sentence denotes It has been shown that a synergy between omega-3 fatty acids and gut microbiota enhances the efficacy of immune checkpoint inhibitors [211].
T312 4833-4837 Sentence denotes 6.3.
T313 4838-4885 Sentence denotes Recommended Daily Allowance and Supplementation
T314 4886-5198 Sentence denotes Since insufficient data are available to establish an estimated average requirement (EAR), the EFSA panel on Dietetic Products, Nutrition, and Allergies (NDA) indicated adequate intake (AI) for adults of 250 mg for eicosapentaenoic acid plus docosahexaenoic acid based on considerations of cardiovascular health.
T315 5199-5347 Sentence denotes For older infants (>6 months of age) and young children, below the age of 24 months, was proposed an adequate intake of 100 mg docosahexaenoic acid.
T316 5348-5459 Sentence denotes For the age period 2 to 18 years, the AI proposed for the adult population should be considered suitable [212].
T317 5461-5465 Sentence denotes 6.4.
T318 5466-5525 Sentence denotes Omega-3 Fatty Acids Supplementation against Viral Infection
T319 5526-5688 Sentence denotes As mentioned above, the omega-3 fatty acids play a crucial role in the resolution of inflammation induced by infections, including in the respiratory tract [196].
T320 5689-5996 Sentence denotes Table 7 summarizes the main studies in which were investigated the link between the omega-3 fatty acids supplementation and respiratory infections/illness, and the potential role in improving the acute lung injury and acute respiratory distress syndrome (ARDS) [213,214,215,216,217,218,219,220,221,222,223].
T321 5997-6173 Sentence denotes Some studies investigated the effects of the omega-3 fatty acids supplementation on infant morbidity, particularly caused by respiratory tract infections, wheezing, and asthma.
T322 6174-6340 Sentence denotes Imhoff et al. showed that DHA supplementation during pregnancy decreased the occurrence of colds in children at 1 month and influenced illness symptom duration [213].
T323 6341-6563 Sentence denotes Pastor et al. in a multicenter, prospective, open-label observational study, which included 1342 infants, showed a higher incidence of bronchiolitis in control versus groups who received omega-3-supplemented formula [214].
T324 6564-6777 Sentence denotes In contrast, in another study aimed to valuate the effect of neonatal DHA supplementation, the hospitalisation for lower respiratory tract problems in the first 18 months for preterm infants was not reduced [215].
T325 6778-7112 Sentence denotes A randomized controlled, trial which included 736 pregnant women and a total of 695 children, showed that the risk of persistent wheeze or asthma was reduced by approximately 7% in the first 5 years of life among children of women who received daily supplementation with omega−3 PUFA (EPA/DHA) during the third trimester of pregnancy.
T326 7113-7238 Sentence denotes It is notable that this effect was most prominent among children of women with low EPA and DHA blood levels at randomization.
T327 7239-7359 Sentence denotes Furthermore, supplementation was also associated with a reduced risk of infections of the lower respiratory tract [216].
T328 7360-7542 Sentence denotes Some studies have demonstrated the effect of omega-3 supplementation also on children’s morbidity, particularly reducing the episodes of upper respiratory tract infections [217,218].
T329 7543-7859 Sentence denotes Malan et al. in a randomized, double-blind, placebo-controlled trial, which included 321 South African children with iron-deficiency, showed that iron supplementation was associated with an increased morbidity, mostly respiratory, but when given in combination with DHA/EPA, this increase in morbidity was prevented.
T330 7860-8042 Sentence denotes Authors suggested that this effect could be explained by the DHA- and EPA-mediated protection against iron-induced oxidative stress and the improved resolution of inflammation [219].
T331 8043-8324 Sentence denotes It has been shown that severe COVID-19 could manifest as a hyperinflammatory syndrome (secondary haemophagocitic lymphohistiocytosis), which is characterized by an important hypercytokinaemia (cytokine storm) with multiorgan failure and ARDS in approximately 50% of patients [220].
T332 8325-8495 Sentence denotes Several studies have been conducted to determinate if omega-3 fatty acids DHA and EPA could modulate systemic inflammatory response and affect plasma cytokine production.
T333 8496-8808 Sentence denotes Thienprasert et al., in a randomized controlled trial, demonstrated that consumption of omega-3 PUFAs was associated with fewer episodes and shorter duration of illness (mainly upper respiratory tract) and with a significantly lower concentration of TGF-beta1 concentration compared with the placebo group [221].
T334 8809-9158 Sentence denotes Two randomized controlled trials, aimed to determinate if omega-3 fatty acids could modulate the systemic inflammatory response, improving the outcomes in patients with acute lung injury, have shown that in the intervention groups there was not a reduction of the biomarkers of systemic inflammation and pulmonary outcomes did not improve [222,223].
T335 9159-9477 Sentence denotes In a recent systematic review, Dushianthan et al. have reported a significant improvement in blood oxygenation and in the duration of ventilator days and ICU length of stay in patients with ARDS who received nutrition containing antioxidants and rich in EPA and DHA, although there was a low quality of evidence [224].
T336 9478-9710 Sentence denotes These findings supported also by results of animal studies [225,226,227], may suggest a potential role for EPA and DHA in reducing the lung injury supporting the resolution of inflammation, probably via the production of SPMs [207].
T337 9711-9773 Sentence denotes However, further trials are needed to support this hypothesis.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1171 3-22 Chemical denotes Omega-3 Fatty Acids MESH:D015525
1180 54-73 Chemical denotes Omega-3 fatty acids MESH:D015525
1181 90-117 Chemical denotes polyunsaturated fatty acids MESH:D005231
1182 119-124 Chemical denotes PUFAs MESH:D005231
1183 188-194 Chemical denotes carbon MESH:D002244
1184 214-232 Chemical denotes omega-3 fatty acid MESH:D015525
1185 236-252 Chemical denotes α-linolenic acid MESH:D017962
1186 294-312 Chemical denotes omega-6 fatty acid MESH:D043371
1187 313-326 Chemical denotes linoleic acid MESH:D019787
1206 612-617 Species denotes human Tax:9606
1207 1190-1196 Species denotes humans Tax:9606
1208 388-401 Chemical denotes Linoleic acid MESH:D019787
1209 416-432 Chemical denotes α-linolenic acid MESH:D017962
1210 447-468 Chemical denotes essential fatty acids MESH:D005228
1211 470-474 Chemical denotes EFAs MESH:D005228
1212 666-682 Chemical denotes α-linolenic acid MESH:D017962
1213 731-752 Chemical denotes eicosapentaenoic acid MESH:D015118
1214 781-801 Chemical denotes docosahexaenoic acid MESH:D004281
1215 821-824 Chemical denotes DHA MESH:C027493
1216 889-908 Chemical denotes omega-6 fatty acids MESH:D043371
1217 972-988 Chemical denotes arachidonic acid MESH:D016718
1218 1006-1022 Chemical denotes α-linolenic acid MESH:D017962
1219 1053-1066 Chemical denotes linoleic acid MESH:D019787
1220 1165-1168 Chemical denotes DHA MESH:C027493
1221 1253-1264 Chemical denotes fatty acids MESH:D005227
1222 1299-1318 Chemical denotes Alfa-linolenic acid
1223 1345-1348 Chemical denotes DHA MESH:C027493
1233 1405-1424 Chemical denotes Omega-3 fatty acids MESH:D015525
1234 1479-1492 Chemical denotes phospholipids MESH:D010743
1235 1604-1615 Chemical denotes eicosanoids MESH:D015777
1236 1729-1736 Chemical denotes omega-3
1237 1741-1756 Chemical denotes omega-6-derived
1238 2224-2242 Chemical denotes omega-3 fatty acid MESH:D015525
1239 2252-2255 Chemical denotes DHA MESH:C027493
1240 1941-1953 Disease denotes inflammation MESH:D007249
1241 2485-2497 Disease denotes inflammation MESH:D007249
1247 3347-3351 Gene denotes CCR5 Gene:1234
1248 2505-2524 Chemical denotes Omega-3 fatty acids MESH:D015525
1249 2638-2650 Disease denotes inflammation MESH:D007249
1250 2852-2864 Disease denotes inflammation MESH:D007249
1251 3478-3490 Disease denotes inflammation MESH:D007249
1253 3504-3523 Chemical denotes Omega-3 Fatty Acids MESH:D015525
1273 3548-3558 Chemical denotes fatty acid MESH:D005227
1274 3690-3697 Chemical denotes omega-3
1275 3768-3792 Chemical denotes phospholipid fatty acids
1276 3860-3872 Chemical denotes phospholipid MESH:D010743
1277 3882-3885 Chemical denotes DHA MESH:C027493
1278 3908-3915 Chemical denotes Omega-3
1279 3968-3979 Chemical denotes fatty acids MESH:D005227
1280 4075-4078 Chemical denotes DHA MESH:C027493
1281 4156-4167 Chemical denotes fatty acids MESH:D005227
1282 4217-4220 Chemical denotes DHA MESH:C027493
1283 4240-4243 Chemical denotes DHA MESH:C027493
1284 4274-4285 Chemical denotes fatty acids MESH:D005227
1285 4386-4393 Chemical denotes omega-3
1286 4398-4411 Chemical denotes omega-6 lipid
1287 4470-4503 Chemical denotes 17,18-epoxy-eicosatetraenoic acid MESH:C070378
1288 4509-4516 Chemical denotes microbe
1289 4527-4562 Chemical denotes 10-hydroxy-cis-12-octadecenoic acid MESH:C000629086
1290 4732-4751 Chemical denotes omega-3 fatty acids MESH:D015525
1291 4619-4631 Disease denotes inflammation MESH:D007249
1297 5209-5216 Species denotes infants Tax:9606
1298 5246-5254 Species denotes children Tax:9606
1299 5101-5122 Chemical denotes eicosapentaenoic acid MESH:D015118
1300 5128-5148 Chemical denotes docosahexaenoic acid MESH:D004281
1301 5326-5346 Chemical denotes docosahexaenoic acid MESH:D004281
1304 5466-5485 Chemical denotes Omega-3 Fatty Acids MESH:D015525
1305 5510-5525 Disease denotes Viral Infection MESH:D001102
1315 5664-5675 Species denotes respiratory Tax:12814
1316 5550-5569 Chemical denotes omega-3 fatty acids MESH:D015525
1317 5773-5792 Chemical denotes omega-3 fatty acids MESH:D015525
1318 5611-5623 Disease denotes inflammation MESH:D007249
1319 5635-5645 Disease denotes infections MESH:D007239
1320 5813-5835 Disease denotes respiratory infections MESH:D012141
1321 5891-5902 Disease denotes lung injury MESH:D055370
1322 5907-5942 Disease denotes acute respiratory distress syndrome MESH:D012128
1323 5944-5948 Disease denotes ARDS MESH:D012128
1347 6274-6282 Species denotes children Tax:9606
1348 6438-6445 Species denotes infants Tax:9606
1349 6747-6754 Species denotes infants Tax:9606
1350 6837-6842 Species denotes women Tax:9606
1351 6862-6870 Species denotes children Tax:9606
1352 6991-6999 Species denotes children Tax:9606
1353 7003-7008 Species denotes women Tax:9606
1354 7169-7177 Species denotes children Tax:9606
1355 7181-7186 Species denotes women Tax:9606
1356 6685-6696 Species denotes respiratory Tax:12814
1357 7335-7346 Species denotes respiratory Tax:12814
1358 6042-6061 Chemical denotes omega-3 fatty acids MESH:D015525
1359 6200-6203 Chemical denotes DHA MESH:C027493
1360 6528-6535 Chemical denotes omega-3
1361 6634-6637 Chemical denotes DHA MESH:C027493
1362 7049-7061 Chemical denotes omega−3 PUFA
1363 7067-7070 Chemical denotes DHA MESH:C027493
1364 7204-7207 Chemical denotes DHA MESH:C027493
1365 6122-6150 Disease denotes respiratory tract infections MESH:D012141
1366 6166-6172 Disease denotes asthma MESH:D001249
1367 6476-6489 Disease denotes bronchiolitis MESH:D001988
1368 6917-6923 Disease denotes asthma MESH:D001249
1369 7311-7321 Disease denotes infections MESH:D007239
1380 7437-7445 Species denotes children Tax:9606
1381 7646-7654 Species denotes children Tax:9606
1382 7761-7772 Species denotes respiratory Tax:12814
1383 7689-7693 Chemical denotes iron MESH:D007501
1384 7809-7812 Chemical denotes DHA MESH:C027493
1385 7921-7924 Chemical denotes DHA MESH:C027493
1386 7962-7966 Chemical denotes iron MESH:D007501
1387 7497-7531 Disease denotes upper respiratory tract infections MESH:D012141
1388 7660-7675 Disease denotes iron-deficiency MESH:C562385
1389 8023-8035 Disease denotes inflammation MESH:D007249
1409 8746-8755 Gene denotes TGF-beta1 Gene:7040
1410 8309-8317 Species denotes patients Tax:9606
1411 8964-8972 Species denotes patients Tax:9606
1412 9335-9343 Species denotes patients Tax:9606
1413 8679-8690 Species denotes respiratory Tax:12814
1414 8379-8398 Chemical denotes omega-3 fatty acids MESH:D015525
1415 8399-8402 Chemical denotes DHA MESH:C027493
1416 8584-8597 Chemical denotes omega-3 PUFAs
1417 8867-8886 Chemical denotes omega-3 fatty acids MESH:D015525
1418 9421-9424 Chemical denotes DHA MESH:C027493
1419 8073-8081 Disease denotes COVID-19 MESH:C000657245
1420 8102-8128 Disease denotes hyperinflammatory syndrome MESH:D061325
1421 8130-8175 Disease denotes secondary haemophagocitic lymphohistiocytosis MESH:D060085
1422 8217-8234 Disease denotes hypercytokinaemia
1423 8257-8275 Disease denotes multiorgan failure MESH:D009102
1424 8280-8284 Disease denotes ARDS MESH:D012128
1425 8984-8995 Disease denotes lung injury MESH:D055370
1426 9096-9108 Disease denotes inflammation MESH:D007249
1427 9349-9353 Disease denotes ARDS MESH:D012128
1431 9593-9596 Chemical denotes DHA MESH:C027493
1432 9613-9624 Disease denotes lung injury MESH:D055370
1433 9654-9666 Disease denotes inflammation MESH:D007249