PMC:7589163 / 28004-29628
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T197 | 334-339 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T67 | 334-339 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T119 | 602-609 | Disease | denotes | rickets | http://purl.obolibrary.org/obo/MONDO_0005520 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T350 | 424-428 | http://purl.obolibrary.org/obo/UBERON_0002481 | denotes | bone |
T351 | 730-731 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T352 | 1034-1038 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 1%–8 |
T353 | 1069-1071 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T354 | 1141-1142 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T355 | 1202-1203 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T356 | 1247-1248 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T357 | 1331-1332 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T358 | 1432-1433 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T359 | 1512-1515 | http://purl.obolibrary.org/obo/CLO_0053001 | denotes | 114 |
T360 | 1547-1548 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T462 | 5-14 | Chemical | denotes | Vitamin D | http://purl.obolibrary.org/obo/CHEBI_89324 |
T463 | 5-12 | Chemical | denotes | Vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T464 | 104-113 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T465 | 104-111 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T466 | 158-167 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T467 | 158-165 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T468 | 448-455 | Chemical | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320 |
T470 | 513-522 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T471 | 513-520 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T472 | 895-904 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T473 | 895-902 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T474 | 1162-1171 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T475 | 1162-1169 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T476 | 1267-1276 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T477 | 1267-1274 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T478 | 1353-1362 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T479 | 1353-1360 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
T480 | 1567-1576 | Chemical | denotes | vitamin D | http://purl.obolibrary.org/obo/CHEBI_27300 |
T481 | 1567-1574 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T102 | 424-443 | http://purl.obolibrary.org/obo/GO_0030282 | denotes | bone mineralization |
T103 | 429-443 | http://purl.obolibrary.org/obo/GO_0110148 | denotes | mineralization |
T104 | 456-467 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T55 | 513-533 | Phenotype | denotes | vitamin D deficiency | http://purl.obolibrary.org/obo/HP_0100512 |
T56 | 602-609 | Phenotype | denotes | rickets | http://purl.obolibrary.org/obo/HP_0002748 |
T57 | 1162-1182 | Phenotype | denotes | vitamin D deficiency | http://purl.obolibrary.org/obo/HP_0100512 |
T58 | 1353-1373 | Phenotype | denotes | vitamin D deficiency | http://purl.obolibrary.org/obo/HP_0100512 |
T59 | 1567-1587 | Phenotype | denotes | vitamin D deficiency | http://purl.obolibrary.org/obo/HP_0100512 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T185 | 0-4 | Sentence | denotes | 5.2. |
T186 | 5-21 | Sentence | denotes | Vitamin D Status |
T187 | 22-137 | Sentence | denotes | There is currently no definitive consensus regarding the optimal concentration of vitamin D in children and adults. |
T188 | 138-505 | Sentence | denotes | Most authors define vitamin D in normal range from 30 to 100 ng/mL, which might be the optimal range to ensure its immunoregulatory effects; insufficient between 20 and 29 ng/mL, and deficient if serum levels are <20 ng/mL (50 nmol/L), since this level is necessary to maintain optimal bone mineralization and calcium homeostasis in 97.5% of the population [109,110]. |
T189 | 506-623 | Sentence | denotes | Severe vitamin D deficiency is defined as <10 ng/mL; below this cut-off, the risk of developing rickets is very high. |
T190 | 624-729 | Sentence | denotes | Concentrations >100 ng/mL may instead be harmful, although toxicity is more commonly seen over 200 ng/mL. |
T191 | 730-945 | Sentence | denotes | A 2016 study [111] combined data from 14 European population studies, including children, adolescents, and adults, and found an estimated prevalence of insufficient vitamin D levels of 13% in the general population. |
T192 | 946-1079 | Sentence | denotes | The prevalence according to age in pediatric populations varied from 4%–7% (1–6 years), 1%–8% (7–14 years) and 12%–40% (15–18 years). |
T193 | 1080-1201 | Sentence | denotes | Italian data usually regards smaller populations and reports a high prevalence of vitamin D deficiency and insufficiency. |
T194 | 1202-1380 | Sentence | denotes | A 2014 study from Stagi and colleagues found a 30% prevalence of vitamin D insufficiency in Italian children and adolescents and a 58.7% prevalence of vitamin D deficiency [112]. |
T195 | 1381-1495 | Sentence | denotes | In the same year, Vierucci and colleagues reported a prevalence of 32.3% insufficiency and 49.9% deficiency [113]. |
T196 | 1496-1624 | Sentence | denotes | Cadario et al. [114] described in Italian newborns a high frequency of vitamin D deficiency (40.1%) and severe deficiency (38%). |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
731 | 5-14 | Chemical | denotes | Vitamin D | MESH:D014807 |
745 | 726-728 | Gene | denotes | mL | Gene:21832 |
746 | 647-649 | Gene | denotes | mL | Gene:21832 |
747 | 555-557 | Gene | denotes | mL | Gene:21832 |
748 | 358-360 | Gene | denotes | mL | Gene:21832 |
749 | 313-315 | Gene | denotes | mL | Gene:21832 |
750 | 202-204 | Gene | denotes | mL | Gene:21832 |
751 | 117-125 | Species | denotes | children | Tax:9606 |
752 | 370-371 | Gene | denotes | L | Gene:21832 |
753 | 104-113 | Chemical | denotes | vitamin D | MESH:D014807 |
754 | 158-167 | Chemical | denotes | vitamin D | MESH:D014807 |
755 | 448-455 | Chemical | denotes | calcium | MESH:D002118 |
756 | 513-522 | Chemical | denotes | vitamin D | MESH:D014807 |
757 | 683-691 | Disease | denotes | toxicity | MESH:D064420 |
769 | 810-818 | Species | denotes | children | Tax:9606 |
770 | 1302-1310 | Species | denotes | children | Tax:9606 |
771 | 895-904 | Chemical | denotes | vitamin D | MESH:D014807 |
772 | 1162-1171 | Chemical | denotes | vitamin D | MESH:D014807 |
773 | 1267-1276 | Chemical | denotes | vitamin D | MESH:D014807 |
774 | 1353-1362 | Chemical | denotes | vitamin D | MESH:D014807 |
775 | 1567-1576 | Chemical | denotes | vitamin D | MESH:D014807 |
776 | 1172-1200 | Disease | denotes | deficiency and insufficiency | MESH:D000309 |
777 | 1277-1290 | Disease | denotes | insufficiency | MESH:D000309 |
778 | 1454-1467 | Disease | denotes | insufficiency | MESH:D000309 |
779 | 1600-1617 | Disease | denotes | severe deficiency | MESH:D045169 |