PMC:7589163 / 27556-28002 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T193","span":{"begin":50,"end":55},"obj":"Body_part"},{"id":"T194","span":{"begin":99,"end":104},"obj":"Body_part"},{"id":"T195","span":{"begin":128,"end":133},"obj":"Body_part"},{"id":"T196","span":{"begin":258,"end":263},"obj":"Body_part"}],"attributes":[{"id":"A193","pred":"fma_id","subj":"T193","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A194","pred":"fma_id","subj":"T194","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A195","pred":"fma_id","subj":"T195","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A196","pred":"fma_id","subj":"T196","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Vitamin D can also regulate FOXP3 expression in T cells, thus inducing the differentiation of this cells to FOXP3+ T regulatory cells (T reg), which have an immunosuppressor activity [105,106], and can promote the secretion of anti-inflammatory IL-10 from T cells [107]. It was also reported in a placebo-controlled trial on healthy adults that high dose vitamin D supplementation significantly increased the frequency of circulating Tregs [108]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T340","span":{"begin":28,"end":33},"obj":"http://purl.obolibrary.org/obo/PR_000001350"},{"id":"T341","span":{"begin":48,"end":55},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T342","span":{"begin":99,"end":104},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T343","span":{"begin":108,"end":113},"obj":"http://purl.obolibrary.org/obo/PR_000001350"},{"id":"T344","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T345","span":{"begin":135,"end":140},"obj":"http://purl.obolibrary.org/obo/CL_0000792"},{"id":"T346","span":{"begin":174,"end":182},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T347","span":{"begin":256,"end":263},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T348","span":{"begin":295,"end":296},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T349","span":{"begin":434,"end":439},"obj":"http://purl.obolibrary.org/obo/CL_0000792"}],"text":"Vitamin D can also regulate FOXP3 expression in T cells, thus inducing the differentiation of this cells to FOXP3+ T regulatory cells (T reg), which have an immunosuppressor activity [105,106], and can promote the secretion of anti-inflammatory IL-10 from T cells [107]. It was also reported in a placebo-controlled trial on healthy adults that high dose vitamin D supplementation significantly increased the frequency of circulating Tregs [108]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T456","span":{"begin":0,"end":9},"obj":"Chemical"},{"id":"T457","span":{"begin":0,"end":7},"obj":"Chemical"},{"id":"T458","span":{"begin":245,"end":247},"obj":"Chemical"},{"id":"T460","span":{"begin":355,"end":364},"obj":"Chemical"},{"id":"T461","span":{"begin":355,"end":362},"obj":"Chemical"}],"attributes":[{"id":"A456","pred":"chebi_id","subj":"T456","obj":"http://purl.obolibrary.org/obo/CHEBI_89324"},{"id":"A457","pred":"chebi_id","subj":"T457","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A458","pred":"chebi_id","subj":"T458","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A459","pred":"chebi_id","subj":"T458","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A460","pred":"chebi_id","subj":"T460","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A461","pred":"chebi_id","subj":"T461","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"}],"text":"Vitamin D can also regulate FOXP3 expression in T cells, thus inducing the differentiation of this cells to FOXP3+ T regulatory cells (T reg), which have an immunosuppressor activity [105,106], and can promote the secretion of anti-inflammatory IL-10 from T cells [107]. It was also reported in a placebo-controlled trial on healthy adults that high dose vitamin D supplementation significantly increased the frequency of circulating Tregs [108]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T101","span":{"begin":214,"end":223},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"text":"Vitamin D can also regulate FOXP3 expression in T cells, thus inducing the differentiation of this cells to FOXP3+ T regulatory cells (T reg), which have an immunosuppressor activity [105,106], and can promote the secretion of anti-inflammatory IL-10 from T cells [107]. It was also reported in a placebo-controlled trial on healthy adults that high dose vitamin D supplementation significantly increased the frequency of circulating Tregs [108]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T183","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"T184","span":{"begin":271,"end":446},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Vitamin D can also regulate FOXP3 expression in T cells, thus inducing the differentiation of this cells to FOXP3+ T regulatory cells (T reg), which have an immunosuppressor activity [105,106], and can promote the secretion of anti-inflammatory IL-10 from T cells [107]. It was also reported in a placebo-controlled trial on healthy adults that high dose vitamin D supplementation significantly increased the frequency of circulating Tregs [108]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"724","span":{"begin":28,"end":33},"obj":"Gene"},{"id":"725","span":{"begin":108,"end":113},"obj":"Gene"},{"id":"726","span":{"begin":245,"end":250},"obj":"Gene"},{"id":"727","span":{"begin":0,"end":9},"obj":"Chemical"},{"id":"728","span":{"begin":355,"end":364},"obj":"Chemical"},{"id":"729","span":{"begin":434,"end":439},"obj":"Chemical"}],"attributes":[{"id":"A724","pred":"tao:has_database_id","subj":"724","obj":"Gene:50943"},{"id":"A725","pred":"tao:has_database_id","subj":"725","obj":"Gene:50943"},{"id":"A726","pred":"tao:has_database_id","subj":"726","obj":"Gene:3586"},{"id":"A727","pred":"tao:has_database_id","subj":"727","obj":"MESH:D014807"},{"id":"A728","pred":"tao:has_database_id","subj":"728","obj":"MESH:D014807"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Vitamin D can also regulate FOXP3 expression in T cells, thus inducing the differentiation of this cells to FOXP3+ T regulatory cells (T reg), which have an immunosuppressor activity [105,106], and can promote the secretion of anti-inflammatory IL-10 from T cells [107]. It was also reported in a placebo-controlled trial on healthy adults that high dose vitamin D supplementation significantly increased the frequency of circulating Tregs [108]."}