PMC:7589163 / 10458-11946
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T76 | 241-255 | Body_part | denotes | marginal liver | http://purl.org/sig/ont/fma/fma81046 |
| T77 | 250-255 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T78 | 648-653 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T79 | 726-732 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T80 | 825-830 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T81 | 925-932 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T82 | 1066-1071 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T83 | 1235-1241 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T84 | 1260-1265 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T85 | 1339-1344 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T86 | 1395-1400 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T24 | 250-255 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T25 | 648-653 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T26 | 825-830 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T27 | 1066-1071 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T28 | 1260-1265 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T29 | 1339-1344 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T30 | 1395-1400 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T38 | 0-20 | Disease | denotes | Vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T39 | 96-116 | Disease | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T40 | 526-546 | Disease | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T41 | 548-563 | Disease | denotes | night blindness | http://purl.obolibrary.org/obo/MONDO_0004588 |
| T42 | 554-563 | Disease | denotes | blindness | http://purl.obolibrary.org/obo/MONDO_0001941 |
| T43 | 868-877 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T44 | 882-894 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T45 | 1031-1043 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T46 | 1159-1179 | Disease | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T47 | 1459-1482 | Disease | denotes | deficiency of vitamin A | http://purl.obolibrary.org/obo/MONDO_0007016 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T121 | 8-9 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T122 | 104-105 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T123 | 224-225 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T124 | 250-255 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T125 | 250-255 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T126 | 266-268 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T127 | 304-305 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T128 | 361-362 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T129 | 435-436 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T130 | 534-535 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T131 | 726-732 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T132 | 966-967 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T133 | 984-985 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T134 | 1147-1148 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T135 | 1167-1168 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T136 | 1235-1241 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T137 | 1323-1324 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T138 | 1339-1344 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T139 | 1339-1344 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T140 | 1393-1394 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T141 | 1395-1400 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T142 | 1395-1400 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T143 | 1457-1458 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T144 | 1481-1482 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T130 | 0-9 | Chemical | denotes | Vitamin A | http://purl.obolibrary.org/obo/CHEBI_17336 |
| T131 | 0-7 | Chemical | denotes | Vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T132 | 96-105 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T133 | 96-103 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T134 | 216-225 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T135 | 216-223 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T136 | 296-305 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T137 | 296-303 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T138 | 353-362 | Chemical | denotes | Vitamin A | http://purl.obolibrary.org/obo/CHEBI_17336 |
| T139 | 353-360 | Chemical | denotes | Vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T140 | 427-436 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T141 | 427-434 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T142 | 506-516 | Chemical | denotes | ophthalmic | http://purl.obolibrary.org/obo/CHEBI_66981 |
| T143 | 526-535 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T144 | 526-533 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T145 | 654-661 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T146 | 708-717 | Chemical | denotes | indicator | http://purl.obolibrary.org/obo/CHEBI_47867 |
| T147 | 831-838 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T148 | 925-932 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T149 | 976-985 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T150 | 976-983 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T151 | 1072-1079 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T152 | 1115-1122 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T153 | 1159-1168 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T154 | 1159-1166 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T155 | 1266-1273 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T156 | 1385-1394 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T157 | 1385-1392 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T158 | 1473-1482 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T159 | 1473-1480 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T40 | 882-894 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T41 | 1031-1043 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T10 | 0-20 | Phenotype | denotes | Vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
| T11 | 96-116 | Phenotype | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
| T12 | 526-546 | Phenotype | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
| T13 | 548-563 | Phenotype | denotes | night blindness | http://purl.obolibrary.org/obo/HP_0000662 |
| T14 | 579-590 | Phenotype | denotes | Bitot spots | http://purl.obolibrary.org/obo/HP_0007462 |
| T15 | 1159-1179 | Phenotype | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T77 | 0-270 | Sentence | denotes | Vitamin A deficiency states in developed countries are rare, but many developing countries have vitamin A deficiency of public health significance, associated with overt signs of deficiency, or subclinical levels of vitamin A depletion with marginal liver reserves [27]. |
| T78 | 271-352 | Sentence | denotes | However, today, marginal vitamin A status is prevalent and difficult to diagnose. |
| T79 | 353-449 | Sentence | denotes | Vitamin A biomarkers have been developed to diagnose different degrees of vitamin A status [28]. |
| T80 | 450-620 | Sentence | denotes | There are biological and functional indicators, such as ophthalmic signs of vitamin A deficiency (night blindness, xerophtalmia, Bitot spots), and biochemical indicators. |
| T81 | 621-718 | Sentence | denotes | As biochemical indicators, serum retinol concentrations are the most common population indicator. |
| T82 | 719-815 | Sentence | denotes | Normal plasma levels are 20–50 µg/dL in infants and increase gradually as children become older. |
| T83 | 816-986 | Sentence | denotes | However, serum retinol concentration is affected by infection and inflammation because RBP is an acute phase protein, thus these conditions may mimic a lack of vitamin A. |
| T84 | 987-1246 | Sentence | denotes | For this reason, RBP linked with markers of inflammation may be used to adjust serum retinol concentration even if the ratio of retinol to RBP is influenced by a status of vitamin A deficiency, because of the increased level of circulating unbound plasma RBP. |
| T85 | 1247-1408 | Sentence | denotes | Furthermore, serum retinol concentration is homeostatically controlled over a wide range of liver reserves, and thus does not reflect the vitamin A liver stores. |
| T86 | 1409-1488 | Sentence | denotes | However, in children, values <10 µg/dL indicate a deficiency of vitamin A [29]. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 214 | 903-906 | Gene | denotes | RBP | Gene:5950 |
| 215 | 1004-1007 | Gene | denotes | RBP | Gene:5950 |
| 216 | 1126-1129 | Gene | denotes | RBP | Gene:5950 |
| 217 | 1242-1245 | Gene | denotes | RBP | Gene:5950 |
| 218 | 759-766 | Species | denotes | infants | Tax:9606 |
| 219 | 793-801 | Species | denotes | children | Tax:9606 |
| 220 | 1421-1429 | Species | denotes | children | Tax:9606 |
| 221 | 216-225 | Chemical | denotes | vitamin A | MESH:D014801 |
| 222 | 296-305 | Chemical | denotes | vitamin A | MESH:D014801 |
| 223 | 353-362 | Chemical | denotes | Vitamin A | MESH:D014801 |
| 224 | 427-436 | Chemical | denotes | vitamin A | MESH:D014801 |
| 225 | 654-661 | Chemical | denotes | retinol | MESH:D014801 |
| 226 | 831-838 | Chemical | denotes | retinol | MESH:D014801 |
| 227 | 976-985 | Chemical | denotes | vitamin A | MESH:D014801 |
| 228 | 1072-1079 | Chemical | denotes | retinol | MESH:D014801 |
| 229 | 1115-1122 | Chemical | denotes | retinol | MESH:D014801 |
| 230 | 1266-1273 | Chemical | denotes | retinol | MESH:D014801 |
| 231 | 1473-1482 | Chemical | denotes | vitamin A | MESH:D014801 |
| 232 | 8-20 | Disease | denotes | A deficiency | MESH:D007153 |
| 233 | 96-116 | Disease | denotes | vitamin A deficiency | MESH:D014802 |
| 234 | 526-546 | Disease | denotes | vitamin A deficiency | MESH:D014802 |
| 235 | 554-563 | Disease | denotes | blindness | MESH:D001766 |
| 236 | 868-877 | Disease | denotes | infection | MESH:D007239 |
| 237 | 882-894 | Disease | denotes | inflammation | MESH:D007249 |
| 238 | 1031-1043 | Disease | denotes | inflammation | MESH:D007249 |
| 239 | 1167-1179 | Disease | denotes | A deficiency | MESH:D007153 |