PMC:7589163 / 10436-11946
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T76 | 263-277 | Body_part | denotes | marginal liver | http://purl.org/sig/ont/fma/fma81046 |
| T77 | 272-277 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T78 | 670-675 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T79 | 748-754 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T80 | 847-852 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T81 | 947-954 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T82 | 1088-1093 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T83 | 1257-1263 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T84 | 1282-1287 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T85 | 1361-1366 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
| T86 | 1417-1422 | Body_part | denotes | liver | http://purl.org/sig/ont/fma/fma7197 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T24 | 272-277 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T25 | 670-675 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T26 | 847-852 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T27 | 1088-1093 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T28 | 1282-1287 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T29 | 1361-1366 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T30 | 1417-1422 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T38 | 22-42 | Disease | denotes | Vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T39 | 118-138 | Disease | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T40 | 548-568 | Disease | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T41 | 570-585 | Disease | denotes | night blindness | http://purl.obolibrary.org/obo/MONDO_0004588 |
| T42 | 576-585 | Disease | denotes | blindness | http://purl.obolibrary.org/obo/MONDO_0001941 |
| T43 | 890-899 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T44 | 904-916 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T45 | 1053-1065 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T46 | 1181-1201 | Disease | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/MONDO_0007016 |
| T47 | 1481-1504 | Disease | denotes | deficiency of vitamin A | http://purl.obolibrary.org/obo/MONDO_0007016 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T120 | 13-14 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T121 | 30-31 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T122 | 126-127 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T123 | 246-247 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T124 | 272-277 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T125 | 272-277 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T126 | 288-290 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T127 | 326-327 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T128 | 383-384 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T129 | 457-458 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T130 | 556-557 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T131 | 748-754 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T132 | 988-989 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T133 | 1006-1007 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T134 | 1169-1170 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T135 | 1189-1190 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T136 | 1257-1263 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T137 | 1345-1346 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T138 | 1361-1366 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T139 | 1361-1366 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T140 | 1415-1416 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T141 | 1417-1422 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T142 | 1417-1422 | http://www.ebi.ac.uk/efo/EFO_0000887 | denotes | liver |
| T143 | 1479-1480 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T144 | 1503-1504 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T128 | 5-14 | Chemical | denotes | Vitamin A | http://purl.obolibrary.org/obo/CHEBI_17336 |
| T129 | 5-12 | Chemical | denotes | Vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T130 | 22-31 | Chemical | denotes | Vitamin A | http://purl.obolibrary.org/obo/CHEBI_17336 |
| T131 | 22-29 | Chemical | denotes | Vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T132 | 118-127 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T133 | 118-125 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T134 | 238-247 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T135 | 238-245 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T136 | 318-327 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T137 | 318-325 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T138 | 375-384 | Chemical | denotes | Vitamin A | http://purl.obolibrary.org/obo/CHEBI_17336 |
| T139 | 375-382 | Chemical | denotes | Vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T140 | 449-458 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T141 | 449-456 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T142 | 528-538 | Chemical | denotes | ophthalmic | http://purl.obolibrary.org/obo/CHEBI_66981 |
| T143 | 548-557 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T144 | 548-555 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T145 | 676-683 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T146 | 730-739 | Chemical | denotes | indicator | http://purl.obolibrary.org/obo/CHEBI_47867 |
| T147 | 853-860 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T148 | 947-954 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T149 | 998-1007 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T150 | 998-1005 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T151 | 1094-1101 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T152 | 1137-1144 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T153 | 1181-1190 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T154 | 1181-1188 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T155 | 1288-1295 | Chemical | denotes | retinol | http://purl.obolibrary.org/obo/CHEBI_50211 |
| T156 | 1407-1416 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T157 | 1407-1414 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
| T158 | 1495-1504 | Chemical | denotes | vitamin A | http://purl.obolibrary.org/obo/CHEBI_12777 |
| T159 | 1495-1502 | Chemical | denotes | vitamin | http://purl.obolibrary.org/obo/CHEBI_33229 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T40 | 904-916 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T41 | 1053-1065 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T10 | 22-42 | Phenotype | denotes | Vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
| T11 | 118-138 | Phenotype | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
| T12 | 548-568 | Phenotype | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
| T13 | 570-585 | Phenotype | denotes | night blindness | http://purl.obolibrary.org/obo/HP_0000662 |
| T14 | 601-612 | Phenotype | denotes | Bitot spots | http://purl.obolibrary.org/obo/HP_0007462 |
| T15 | 1181-1201 | Phenotype | denotes | vitamin A deficiency | http://purl.obolibrary.org/obo/HP_0004905 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T75 | 0-4 | Sentence | denotes | 3.2. |
| T76 | 5-21 | Sentence | denotes | Vitamin A Status |
| T77 | 22-292 | Sentence | denotes | Vitamin A deficiency states in developed countries are rare, but many developing countries have vitamin A deficiency of public health significance, associated with overt signs of deficiency, or subclinical levels of vitamin A depletion with marginal liver reserves [27]. |
| T78 | 293-374 | Sentence | denotes | However, today, marginal vitamin A status is prevalent and difficult to diagnose. |
| T79 | 375-471 | Sentence | denotes | Vitamin A biomarkers have been developed to diagnose different degrees of vitamin A status [28]. |
| T80 | 472-642 | Sentence | denotes | There are biological and functional indicators, such as ophthalmic signs of vitamin A deficiency (night blindness, xerophtalmia, Bitot spots), and biochemical indicators. |
| T81 | 643-740 | Sentence | denotes | As biochemical indicators, serum retinol concentrations are the most common population indicator. |
| T82 | 741-837 | Sentence | denotes | Normal plasma levels are 20–50 µg/dL in infants and increase gradually as children become older. |
| T83 | 838-1008 | Sentence | denotes | However, serum retinol concentration is affected by infection and inflammation because RBP is an acute phase protein, thus these conditions may mimic a lack of vitamin A. |
| T84 | 1009-1268 | Sentence | denotes | For this reason, RBP linked with markers of inflammation may be used to adjust serum retinol concentration even if the ratio of retinol to RBP is influenced by a status of vitamin A deficiency, because of the increased level of circulating unbound plasma RBP. |
| T85 | 1269-1430 | Sentence | denotes | Furthermore, serum retinol concentration is homeostatically controlled over a wide range of liver reserves, and thus does not reflect the vitamin A liver stores. |
| T86 | 1431-1510 | Sentence | denotes | However, in children, values <10 µg/dL indicate a deficiency of vitamin A [29]. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 187 | 5-14 | Chemical | denotes | Vitamin A | MESH:D014801 |
| 214 | 925-928 | Gene | denotes | RBP | Gene:5950 |
| 215 | 1026-1029 | Gene | denotes | RBP | Gene:5950 |
| 216 | 1148-1151 | Gene | denotes | RBP | Gene:5950 |
| 217 | 1264-1267 | Gene | denotes | RBP | Gene:5950 |
| 218 | 781-788 | Species | denotes | infants | Tax:9606 |
| 219 | 815-823 | Species | denotes | children | Tax:9606 |
| 220 | 1443-1451 | Species | denotes | children | Tax:9606 |
| 221 | 238-247 | Chemical | denotes | vitamin A | MESH:D014801 |
| 222 | 318-327 | Chemical | denotes | vitamin A | MESH:D014801 |
| 223 | 375-384 | Chemical | denotes | Vitamin A | MESH:D014801 |
| 224 | 449-458 | Chemical | denotes | vitamin A | MESH:D014801 |
| 225 | 676-683 | Chemical | denotes | retinol | MESH:D014801 |
| 226 | 853-860 | Chemical | denotes | retinol | MESH:D014801 |
| 227 | 998-1007 | Chemical | denotes | vitamin A | MESH:D014801 |
| 228 | 1094-1101 | Chemical | denotes | retinol | MESH:D014801 |
| 229 | 1137-1144 | Chemical | denotes | retinol | MESH:D014801 |
| 230 | 1288-1295 | Chemical | denotes | retinol | MESH:D014801 |
| 231 | 1495-1504 | Chemical | denotes | vitamin A | MESH:D014801 |
| 232 | 30-42 | Disease | denotes | A deficiency | MESH:D007153 |
| 233 | 118-138 | Disease | denotes | vitamin A deficiency | MESH:D014802 |
| 234 | 548-568 | Disease | denotes | vitamin A deficiency | MESH:D014802 |
| 235 | 576-585 | Disease | denotes | blindness | MESH:D001766 |
| 236 | 890-899 | Disease | denotes | infection | MESH:D007239 |
| 237 | 904-916 | Disease | denotes | inflammation | MESH:D007249 |
| 238 | 1053-1065 | Disease | denotes | inflammation | MESH:D007249 |
| 239 | 1189-1201 | Disease | denotes | A deficiency | MESH:D007153 |