PMC:7574920 / 37005-38084
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T145 | 123-126 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T146 | 814-817 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T317 | 93-94 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T318 | 173-183 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | instrument |
| T319 | 259-260 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T320 | 282-283 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T321 | 943-944 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T322 | 1039-1040 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T323 | 1071-1078 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T72 | 123-126 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T73 | 268-273 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T74 | 386-394 | Chemical | denotes | reagents | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T75 | 533-541 | Chemical | denotes | reagents | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T76 | 606-614 | Chemical | denotes | reagents | http://purl.obolibrary.org/obo/CHEBI_33893 |
| T77 | 814-817 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 255 | 268-273 | Chemical | denotes | water | MESH:D014867 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T219 | 42-44 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T220 | 60-62 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T221 | 76-78 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T222 | 123-140 | http://purl.obolibrary.org/obo/GO_0006277 | denotes | DNA amplification |
| T223 | 218-220 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T224 | 314-316 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T225 | 403-405 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T226 | 454-456 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T227 | 525-527 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T228 | 598-600 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T229 | 674-676 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T230 | 768-770 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T231 | 891-893 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
| T232 | 980-982 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | RT |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T276 | 0-68 | Sentence | denotes | There are several differences between the RT-LAMP assay and RT-qPCR. |
| T277 | 69-298 | Sentence | denotes | First, RT-qPCR requires a thermocycler to conduct the DNA amplification reaction, which is an expensive instrument, whereas isothermal incubation of RT-LAMP reactions can be conducted using a simple water bath or a heating block. |
| T278 | 299-373 | Sentence | denotes | This makes the RT-LAMP assay more amenable for point-of-care applications. |
| T279 | 374-491 | Sentence | denotes | Second, the reagents for the RT-LAMP assay are different from the ones used for RT-qPCR and are supplier independent. |
| T280 | 492-662 | Sentence | denotes | According to the supplier of the RT-LAMP reagents used in this study (New England Biolabs), production of RT-LAMP reagents can be easily ramped up to satisfy high demand. |
| T281 | 663-837 | Sentence | denotes | Third, the RT-LAMP assay, when combined with LAMP-sequencing, is suitable for analyzing large numbers of RT-LAMP reactions owing to the fully scalable DNA barcoding strategy. |
| T282 | 838-975 | Sentence | denotes | In contrast, there are several hurdles to scaling up RT-qPCR assays, the major hurdle being the need for a large number of thermocyclers. |
| T283 | 976-1079 | Sentence | denotes | The RT-LAMP assay overcomes this problem and therefore will be a more scalable method for mass testing. |