PMC:7573190 / 2909-3515 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7573190","sourcedb":"PMC","sourceid":"7573190","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7573190","text":"The controversy of NO's role in insulin secretion may depend on the use of various β-cell lines with different qualitative/quantitative secretory reaction patterns, incubation of islets/β-cells in high or low glucose media, using different NOS inhibitors, or different types of extracellular/intracellular NO donors. Also varying enzymatic activities of the different isoforms of NOS may be of importance. This review focuses on the role of NO in the regulation of insulin secretion as well as the possible factors and reasons which may contribute to discrepancies in the results between different studies.","tracks":[]}