PMC:7573174 / 4342-5314 JSONTXT

{"project":"2_test","denotations":[{"id":"33088250-26646318-29803036","span":{"begin":748,"end":750},"obj":"26646318"},{"id":"33088250-28319779-29803037","span":{"begin":771,"end":774},"obj":"28319779"}],"text":"This review provides a brief introduction of the supramolecular biomaterials made of small molecules (especially peptides and peptide derivatives) because the ordered structures of molecular assemblies provide a versatile platform for designing emergent functions. We start with introducing common triggering mechanisms to initiate self-assembly. By discussing representative examples of supramolecular biomaterials formed intercellularly, peri/intracellularly, or subcellularly, we emphasize the applications of supramolecular biomaterials in the biomedicine, including tissue engineering, cancer therapy, drug delivery, and molecular imaging. Since a few comprehensive reviews of the related subjects already have been published (Du et al., 2015[17]; Zhou et al., 2017[124]), we mainly focus on representative examples in the past five years. Polymer supramolecular assemblies will not be included because of considerable disorders associated with conventional polymers."}

{"project":"MyTest","denotations":[{"id":"33088250-26646318-29803036","span":{"begin":748,"end":750},"obj":"26646318"},{"id":"33088250-28319779-29803037","span":{"begin":771,"end":774},"obj":"28319779"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"This review provides a brief introduction of the supramolecular biomaterials made of small molecules (especially peptides and peptide derivatives) because the ordered structures of molecular assemblies provide a versatile platform for designing emergent functions. We start with introducing common triggering mechanisms to initiate self-assembly. By discussing representative examples of supramolecular biomaterials formed intercellularly, peri/intracellularly, or subcellularly, we emphasize the applications of supramolecular biomaterials in the biomedicine, including tissue engineering, cancer therapy, drug delivery, and molecular imaging. Since a few comprehensive reviews of the related subjects already have been published (Du et al., 2015[17]; Zhou et al., 2017[124]), we mainly focus on representative examples in the past five years. Polymer supramolecular assemblies will not be included because of considerable disorders associated with conventional polymers."}