PMC:7572969 / 6457-7302 JSONTXT

{"project":"2_test","denotations":[{"id":"33074395-22441582-26648284","span":{"begin":188,"end":190},"obj":"22441582"},{"id":"33074395-19384547-26648285","span":{"begin":192,"end":194},"obj":"19384547"},{"id":"33074395-19384547-26648286","span":{"begin":386,"end":388},"obj":"19384547"},{"id":"33074395-22441582-26648287","span":{"begin":506,"end":508},"obj":"22441582"},{"id":"33074395-19384547-26648288","span":{"begin":664,"end":666},"obj":"19384547"},{"id":"33074395-23164552-26648289","span":{"begin":668,"end":670},"obj":"23164552"}],"text":"Materials and methods\n\nSubjects\nClinical data of 43 participants belonging to two different studies, both conducted within the Amsterdam UMC, location VUmc, were included retrospectively [20, 21]. Thirteen subjects [6 cognitively unimpaired (CU), 1 mild cognitive impaired (MCI), 6 AD] were part of a TRT study and underwent arterial sampling, as described in detail by Tolboom et al. [21]. The other 30 subjects (11 CU, 12 MCI, 7 AD) were part of a longitudinal study as described by Ossenkoppele et al. [20]. In brief, all subjects received standard dementia screening for diagnostic purposes and amyloid PET scans were assessed visually (positive or negative) [21, 22]. Before enrolment, all participants provided written informed consent and the Medical Ethics Review Committee of the Amsterdam UMC, location VUmc, had approved both studies."}

{"project":"MyTest","denotations":[{"id":"33074395-22441582-26648284","span":{"begin":188,"end":190},"obj":"22441582"},{"id":"33074395-19384547-26648285","span":{"begin":192,"end":194},"obj":"19384547"},{"id":"33074395-19384547-26648286","span":{"begin":386,"end":388},"obj":"19384547"},{"id":"33074395-22441582-26648287","span":{"begin":506,"end":508},"obj":"22441582"},{"id":"33074395-19384547-26648288","span":{"begin":664,"end":666},"obj":"19384547"},{"id":"33074395-23164552-26648289","span":{"begin":668,"end":670},"obj":"23164552"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Materials and methods\n\nSubjects\nClinical data of 43 participants belonging to two different studies, both conducted within the Amsterdam UMC, location VUmc, were included retrospectively [20, 21]. Thirteen subjects [6 cognitively unimpaired (CU), 1 mild cognitive impaired (MCI), 6 AD] were part of a TRT study and underwent arterial sampling, as described in detail by Tolboom et al. [21]. The other 30 subjects (11 CU, 12 MCI, 7 AD) were part of a longitudinal study as described by Ossenkoppele et al. [20]. In brief, all subjects received standard dementia screening for diagnostic purposes and amyloid PET scans were assessed visually (positive or negative) [21, 22]. Before enrolment, all participants provided written informed consent and the Medical Ethics Review Committee of the Amsterdam UMC, location VUmc, had approved both studies."}