> top > docs > PMC:7571312 > spans > 87984-89192 > annotations

PMC:7571312 / 87984-89192 JSONTXT

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LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T627 510-511 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T628 626-637 http://purl.obolibrary.org/obo/CLO_0007699 denotes mg (63%) of
T629 626-637 http://purl.obolibrary.org/obo/CLO_0050808 denotes mg (63%) of
T630 1067-1069 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T631 1105-1110 http://purl.obolibrary.org/obo/CLO_0007706 denotes M + H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1555 29-32 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T1556 63-69 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T1558 70-76 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T1559 77-82 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T1560 83-91 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T1561 92-98 Chemical denotes pentyl http://purl.obolibrary.org/obo/CHEBI_25902
T1562 102-109 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T1564 110-119 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T1565 110-112 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1566 113-119 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T1567 122-133 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T1569 211-217 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T1570 220-223 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T1571 254-260 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T1573 261-267 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T1574 268-273 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T1575 274-282 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T1576 284-297 Chemical denotes 3-methylbutyl http://purl.obolibrary.org/obo/CHEBI_30359
T1577 301-308 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T1579 309-318 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T1580 309-311 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1581 312-318 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T1582 321-332 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T1584 350-352 Chemical denotes N2 http://purl.obolibrary.org/obo/CHEBI_17997
T1585 354-373 Chemical denotes tert-butoxycarbonyl http://purl.obolibrary.org/obo/CHEBI_48502
T1586 386-392 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T1587 395-398 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T1588 429-435 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T1590 436-442 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T1591 591-599 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T1592 600-610 Chemical denotes chloroform http://purl.obolibrary.org/obo/CHEBI_35255
T1593 680-682 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1594 688-692 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T1595 709-711 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1596 733-735 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1597 757-759 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1598 771-773 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1599 785-787 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1600 809-811 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1601 833-835 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1602 857-859 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1603 882-884 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1604 907-909 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1605 921-923 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1606 935-937 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1607 977-979 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1608 991-993 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1609 1005-1007 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T43246 1067-1069 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T511 0-133 Sentence denotes N-((1S)-1-{[((1S)-3-Chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}pentyl)-4-methoxy-1H-indole-2-carboxamide
T512 134-530 Sentence denotes Following the procedure described for the preparation of N-((1S)-1-{[((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-4-methoxy-1H-indole-2-carboxamide but substituting N2-(tert-butoxycarbonyl)-N1-((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)-l-norleucinamide and making no other critical variations provided a crude yellow foam.
T513 531-679 Sentence denotes This material was purified by Biotage MPLC (25 M column, 3% methanol/chloroform) to afford 254 mg (63%) of the title compound as an off-white solid.
T514 680-1172 Sentence denotes 1H NMR (DMSO-d6) δ 11.56 (s, 1H), 8.57 (d, J = 8 Hz, 1H), 8.39 (d, J = 4 Hz, 1H), 7.62 (s, 1H), 7.36 (s, 1H), 7.08 (t, J = 8 Hz, 1H), 6.99 (d, J = 8 Hz, 1H), 6.49 (d, J = 8 Hz, 1H), 4.58 (d, J = 16 Hz, 1H), 4.56 (d, J = 16 Hz, 1H), 4.43 (m, 1H), 4.35 (m, 1H), 3.87 (s, 3H), 3.09 (m, 2H), 2.27 (m, 1H), 2.08 (m, 1H), 1.97 (m, 1H), 1.74–1.54 (m, 4H), 1.30 (m, 4H), 0.86 (t, J = 8 Hz, 3H); MS (ESI+) for C24H31N4O5Cl m/z 491.1 (M + H)+; anal. calcd for C24H31ClN4O5: C, 58.71; H, 6.36; N, 11.41.
T515 1173-1208 Sentence denotes Found: C, 58.66; H, 6.45; N, 11.22.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1729 591-599 Chemical denotes methanol MESH:D000432
1730 600-610 Chemical denotes chloroform MESH:D002725
1731 1130-1142 Chemical denotes C24H31ClN4O5
1732 1144-1145 Chemical denotes C MESH:D002244
1733 1163-1164 Chemical denotes N MESH:D009584
1734 1180-1181 Chemical denotes C MESH:D002244
1735 1199-1200 Chemical denotes N MESH:D009584