PMC:7571312 / 83920-84756
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T94 | 568-571 | Body_part | denotes | gum | http://purl.org/sig/ont/fma/fma59762 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T606 | 396-397 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T607 | 559-560 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T608 | 568-571 | http://www.ebi.ac.uk/efo/EFO_0001925 | denotes | gum |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1371 | 25-28 | Chemical | denotes | oxo | http://purl.obolibrary.org/obo/CHEBI_46629 |
T1372 | 59-65 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
T1374 | 66-72 | Chemical | denotes | propyl | http://purl.obolibrary.org/obo/CHEBI_26308 |
T1375 | 74-76 | Chemical | denotes | N2 | http://purl.obolibrary.org/obo/CHEBI_17997 |
T1376 | 78-97 | Chemical | denotes | tert-butoxycarbonyl | http://purl.obolibrary.org/obo/CHEBI_48502 |
T1377 | 99-101 | Chemical | denotes | N2 | http://purl.obolibrary.org/obo/CHEBI_17997 |
T1378 | 102-108 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
T1380 | 180-190 | Chemical | denotes | tert-butyl | http://purl.obolibrary.org/obo/CHEBI_30355 |
T1381 | 185-190 | Chemical | denotes | butyl | http://purl.obolibrary.org/obo/CHEBI_41264 |
T1382 | 222-225 | Chemical | denotes | oxo | http://purl.obolibrary.org/obo/CHEBI_46629 |
T1383 | 256-262 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
T1385 | 263-269 | Chemical | denotes | propyl | http://purl.obolibrary.org/obo/CHEBI_26308 |
T1386 | 270-275 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T1387 | 298-308 | Chemical | denotes | 2-oxoethyl | http://purl.obolibrary.org/obo/CHEBI_46886 |
T1388 | 309-318 | Chemical | denotes | carbamate | http://purl.obolibrary.org/obo/CHEBI_13941 |
T1389 | 336-339 | Chemical | denotes | Boc | http://purl.obolibrary.org/obo/CHEBI_48502 |
T1390 | 342-348 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
T1392 | 349-352 | Chemical | denotes | Leu | http://purl.obolibrary.org/obo/CHEBI_15603|http://purl.obolibrary.org/obo/CHEBI_25017|http://purl.obolibrary.org/obo/CHEBI_30006 |
T1395 | 488-496 | Chemical | denotes | methanol | http://purl.obolibrary.org/obo/CHEBI_17790 |
T1396 | 497-512 | Chemical | denotes | dichloromethane | http://purl.obolibrary.org/obo/CHEBI_15767 |
T1397 | 573-575 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
T1398 | 590-595 | Chemical | denotes | CDCl3 | http://purl.obolibrary.org/obo/CHEBI_85365 |
T1399 | 628-630 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
T1400 | 642-644 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
T1401 | 751-753 | Chemical | denotes | 1H | http://purl.obolibrary.org/obo/CHEBI_49637 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T494 | 0-122 | Sentence | denotes | N1-((1S)-3-(Benzyloxy)-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)-N2-(tert-butoxycarbonyl)-N2-methyl-l-leucinamide |
T495 | 123-414 | Sentence | denotes | Following the procedure described for the preparation of tert-butyl [(1S)-2-[((1S)-3-(benzyloxy)-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]-1-(cyclohexylmethyl)-2-oxoethyl]carbamate but substituting Boc-N-methyl-Leu and making noncritical variations provided a crude brown oil. |
T496 | 415-572 | Sentence | denotes | This material was purified by Biotage flash chromatography, eluting with methanol/dichloromethane to afford the title compound (123 mg, 47%) as a yellow gum. |
T497 | 573-836 | Sentence | denotes | 1H NMR (400 MHz, CDCl3) δ 7.22–7.33 (m, 5H), 5.76 (bd, 1H), 4.73 (s, 1H), 4.46–4.59 (m, 2H), 4.08–4.27 (m, 2H), 3.14–3.28 (m, 2H), 2.68 (s, 3H), 2.16–2.38 (m, 2H), 1.88–2.00 (m, 1H), 1.56–1.86 (m, 5H), 1.41 (s, 9H), 0.94 (d, J = 8 Hz, 3H), 0.89 (d, J = 8 Hz, 3H). |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1691 | 336-339 | Gene | denotes | Boc | Gene:91653 |
1692 | 488-496 | Chemical | denotes | methanol | MESH:D000432 |
1693 | 497-512 | Chemical | denotes | dichloromethane | MESH:D008752 |