PMC:7571312 / 6519-6908
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T36 | 196-200 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T40961 | 9-13 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2, a |
| T60248 | 66-68 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T5489 | 137-139 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T9645 | 140-143 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | M–1 |
| T53142 | 140-143 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | M–1 |
| T23219 | 140-143 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | M–1 |
| T80219 | 140-143 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | M–1 |
| T91123 | 140-143 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | M–1 |
| T26503 | 144-147 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | s–1 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T68 | 42-48 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T70 | 57-62 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T71 | 66-68 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T30 | 0-389 | Sentence | denotes | Compound 2, a derivative that contains an indole capping group at P2, displayed modest levels of irreversible inhibition (kobs/I = 586 ± 11 M–1 s–1) that enabled cocrystallization in complex with SARS CoV-1 3CLpro (PDB code 6XHO).29 Comparison of this structure with the complex of 1 in HRV 3Cpro helped to rationalize the poor performance of the warhead, which had been successful in HRV. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 194 | 122-126 | Species | denotes | kobs | Tax:59530 |
| 195 | 196-204 | Species | denotes | SARS CoV | Tax:694009 |
| 200 | 287-290 | Species | denotes | HRV | Tax:169066 |
| 201 | 385-388 | Species | denotes | HRV | Tax:169066 |