PMC:7571312 / 5284-5937
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T30 | 14-18 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T31 | 625-629 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6787 | 29-30 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T62466 | 110-115 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T96017 | 251-252 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T76689 | 278-280 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T22773 | 565-566 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T69827 | 616-617 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T53 | 253-256 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
| T54 | 278-280 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T55 | 539-547 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T56 | 643-652 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T24 | 0-281 | Sentence | denotes | Following the SARS outbreak, a CoV-1 3CLpro homology model was published in 2003 with comparisons made to the human rhinovirus (HRV) 3Cpro.28 Although these two proteases share very little sequence conservation, the substrate consensus sequences have a Gln residue in common at P1. |
| T25 | 282-503 | Sentence | denotes | Analysis of the HRV 3Cpro crystal structure with 1 (rupintrivir; Figure 2) revealed binding interactions that are like those observed for 1 bound to TGEV 3CLpro, which was used in the construction of their homology model. |
| T26 | 504-653 | Sentence | denotes | The authors concluded that Michael acceptor 1 would serve as a starting point to expedite the identification of a potent SARS CoV-1 3CLpro inhibitor. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 144 | 31-34 | Species | denotes | CoV | Tax:11118 |
| 145 | 110-126 | Species | denotes | human rhinovirus | Tax:169066 |
| 146 | 431-435 | Species | denotes | TGEV | Tax:11149 |
| 147 | 625-633 | Species | denotes | SARS CoV | Tax:694009 |
| 148 | 128-131 | Species | denotes | HRV | Tax:169066 |
| 149 | 298-301 | Species | denotes | HRV | Tax:169066 |
| 150 | 253-256 | Chemical | denotes | Gln | MESH:D005973 |
| 151 | 334-345 | Chemical | denotes | rupintrivir | MESH:C118874 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 33054210-12746549-61913453 | 139-141 | 12746549 | denotes | 28 |