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PMC:7571312 / 5284-5937 JSONTXT

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LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T30 14-18 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T31 625-629 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T6787 29-30 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T62466 110-115 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T96017 251-252 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76689 278-280 http://purl.obolibrary.org/obo/CLO_0008285 denotes P1
T22773 565-566 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69827 616-617 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T53 253-256 Chemical denotes Gln http://purl.obolibrary.org/obo/CHEBI_30011
T54 278-280 Chemical denotes P1 http://purl.obolibrary.org/obo/CHEBI_60949
T55 539-547 Chemical denotes acceptor http://purl.obolibrary.org/obo/CHEBI_15339
T56 643-652 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T24 0-281 Sentence denotes Following the SARS outbreak, a CoV-1 3CLpro homology model was published in 2003 with comparisons made to the human rhinovirus (HRV) 3Cpro.28 Although these two proteases share very little sequence conservation, the substrate consensus sequences have a Gln residue in common at P1.
T25 282-503 Sentence denotes Analysis of the HRV 3Cpro crystal structure with 1 (rupintrivir; Figure 2) revealed binding interactions that are like those observed for 1 bound to TGEV 3CLpro, which was used in the construction of their homology model.
T26 504-653 Sentence denotes The authors concluded that Michael acceptor 1 would serve as a starting point to expedite the identification of a potent SARS CoV-1 3CLpro inhibitor.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
144 31-34 Species denotes CoV Tax:11118
145 110-126 Species denotes human rhinovirus Tax:169066
146 431-435 Species denotes TGEV Tax:11149
147 625-633 Species denotes SARS CoV Tax:694009
148 128-131 Species denotes HRV Tax:169066
149 298-301 Species denotes HRV Tax:169066
150 253-256 Chemical denotes Gln MESH:D005973
151 334-345 Chemical denotes rupintrivir MESH:C118874

2_test

Id Subject Object Predicate Lexical cue
33054210-12746549-61913453 139-141 12746549 denotes 28