PMC:7571312 / 31740-32255
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T67 | 226-229 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T68 | 269-273 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T69 | 463-468 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T70 | 476-480 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T8 | 476-480 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T79 | 200-216 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T309 | 53-54 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T310 | 64-71 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T311 | 96-104 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T312 | 129-135 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T313 | 148-153 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T314 | 194-199 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T315 | 217-222 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T316 | 237-242 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T317 | 269-273 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T318 | 385-393 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T319 | 400-401 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T320 | 426-431 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T321 | 457-468 | http://purl.obolibrary.org/obo/CLO_0052043 | denotes | MRC-5 cells |
| T322 | 457-468 | http://purl.obolibrary.org/obo/CLO_0052044 | denotes | MRC-5 cells |
| T323 | 457-468 | http://purl.obolibrary.org/obo/CLO_0052045 | denotes | MRC-5 cells |
| T324 | 470-475 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T325 | 476-480 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T326 | 476-480 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T538 | 4-13 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T539 | 86-95 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T540 | 409-418 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T26 | 376-393 | http://purl.obolibrary.org/obo/GO_0008233 | denotes | protease activity |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T211 | 0-82 | Sentence | denotes | The antiviral specificity of 4 was evaluated against a panel of viruses (Table 6). |
| T212 | 83-282 | Sentence | denotes | No antiviral activity was observed when 4 was tested against two human rhinovirus strains (HRV-14 and HRV-16), human immunodeficiency virus-1 (HIV-1), or human cytomegalovirus (HCMV) in cell culture. |
| T213 | 283-336 | Sentence | denotes | This compound also does not inhibit the HCV replicon. |
| T214 | 337-515 | Sentence | denotes | As anticipated by the potent hCoV 229E protease activity, 4 is a potent inhibitor of the human coronavirus hCoV 229E in MRC-5 cells (human lung-derived) with an EC50 of 0.090 μM. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T6 | 200-216 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 808 | 148-164 | Species | denotes | human rhinovirus | Tax:169066 |
| 809 | 174-180 | Species | denotes | HRV-14 | Tax:12131 |
| 810 | 237-258 | Species | denotes | human cytomegalovirus | Tax:10359 |
| 811 | 366-375 | Species | denotes | hCoV 229E | Tax:11137 |
| 812 | 426-443 | Species | denotes | human coronavirus | Tax:694448 |
| 813 | 444-453 | Species | denotes | hCoV 229E | Tax:11137 |
| 814 | 470-475 | Species | denotes | human | Tax:9606 |
| 815 | 260-264 | Species | denotes | HCMV | Tax:10359 |
| 816 | 200-232 | Disease | denotes | immunodeficiency virus-1 (HIV-1) | MESH:D015658 |
| 817 | 457-462 | CellLine | denotes | MRC-5 | CVCL:0440 |