PMC:7571312 / 30826-31047 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T75","span":{"begin":182,"end":186},"obj":"Disease"}],"attributes":[{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Testing revealed that 4 demonstrates potent inhibition of the related hCoV 229E protease (IC50 = 0.004 μM) but more importantly, given the current global pandemic, potently inhibits SARS CoV-2 3CLpro with a Ki of 0.27 nM."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T295","span":{"begin":0,"end":7},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T296","span":{"begin":205,"end":206},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Testing revealed that 4 demonstrates potent inhibition of the related hCoV 229E protease (IC50 = 0.004 μM) but more importantly, given the current global pandemic, potently inhibits SARS CoV-2 3CLpro with a Ki of 0.27 nM."}

{"project":"LitCovid-sentences","denotations":[{"id":"T193","span":{"begin":0,"end":221},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Testing revealed that 4 demonstrates potent inhibition of the related hCoV 229E protease (IC50 = 0.004 μM) but more importantly, given the current global pandemic, potently inhibits SARS CoV-2 3CLpro with a Ki of 0.27 nM."}

{"project":"LitCovid-PubTator","denotations":[{"id":"759","span":{"begin":70,"end":79},"obj":"Species"},{"id":"760","span":{"begin":182,"end":192},"obj":"Species"}],"attributes":[{"id":"A759","pred":"tao:has_database_id","subj":"759","obj":"Tax:11137"},{"id":"A760","pred":"tao:has_database_id","subj":"760","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Testing revealed that 4 demonstrates potent inhibition of the related hCoV 229E protease (IC50 = 0.004 μM) but more importantly, given the current global pandemic, potently inhibits SARS CoV-2 3CLpro with a Ki of 0.27 nM."}