PMC:7571312 / 26236-26410 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T254","span":{"begin":116,"end":117},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"These derivatives lack the lipophilic aryl ring and NH hydrogen bond donor present in the indole P3 cap and exhibit a pronounced reduction in enzymatic and antiviral potency."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T448","span":{"begin":52,"end":54},"obj":"Chemical"},{"id":"T450","span":{"begin":55,"end":63},"obj":"Chemical"},{"id":"T451","span":{"begin":69,"end":74},"obj":"Chemical"},{"id":"T452","span":{"begin":90,"end":96},"obj":"Chemical"},{"id":"T454","span":{"begin":156,"end":165},"obj":"Chemical"}],"attributes":[{"id":"A448","pred":"chebi_id","subj":"T448","obj":"http://purl.obolibrary.org/obo/CHEBI_29339"},{"id":"A449","pred":"chebi_id","subj":"T448","obj":"http://purl.obolibrary.org/obo/CHEBI_73424"},{"id":"A450","pred":"chebi_id","subj":"T450","obj":"http://purl.obolibrary.org/obo/CHEBI_49637"},{"id":"A451","pred":"chebi_id","subj":"T451","obj":"http://purl.obolibrary.org/obo/CHEBI_17891"},{"id":"A452","pred":"chebi_id","subj":"T452","obj":"http://purl.obolibrary.org/obo/CHEBI_16881"},{"id":"A453","pred":"chebi_id","subj":"T452","obj":"http://purl.obolibrary.org/obo/CHEBI_35581"},{"id":"A454","pred":"chebi_id","subj":"T454","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"These derivatives lack the lipophilic aryl ring and NH hydrogen bond donor present in the indole P3 cap and exhibit a pronounced reduction in enzymatic and antiviral potency."}

{"project":"LitCovid-sentences","denotations":[{"id":"T164","span":{"begin":0,"end":174},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"These derivatives lack the lipophilic aryl ring and NH hydrogen bond donor present in the indole P3 cap and exhibit a pronounced reduction in enzymatic and antiviral potency."}

{"project":"LitCovid-PubTator","denotations":[{"id":"638","span":{"begin":55,"end":63},"obj":"Chemical"},{"id":"639","span":{"begin":90,"end":99},"obj":"Chemical"}],"attributes":[{"id":"A638","pred":"tao:has_database_id","subj":"638","obj":"MESH:D006859"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"These derivatives lack the lipophilic aryl ring and NH hydrogen bond donor present in the indole P3 cap and exhibit a pronounced reduction in enzymatic and antiviral potency."}