PMC:7571312 / 2093-2441 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T72980","span":{"begin":86,"end":94},"obj":"Body_part"},{"id":"T62636","span":{"begin":261,"end":269},"obj":"Body_part"}],"attributes":[{"id":"A85018","pred":"fma_id","subj":"T72980","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A65071","pred":"fma_id","subj":"T62636","obj":"http://purl.org/sig/ont/fma/fma82751"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T22","span":{"begin":136,"end":140},"obj":"Disease"},{"id":"T23","span":{"begin":330,"end":334},"obj":"Disease"}],"attributes":[{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T48219","span":{"begin":161,"end":162},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":86,"end":94},"obj":"Chemical"},{"id":"T13","span":{"begin":261,"end":269},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_15356"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T3","span":{"begin":112,"end":129},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T4","span":{"begin":112,"end":129},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"LitCovid-sentences","denotations":[{"id":"T12","span":{"begin":0,"end":348},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"LitCovid-PubTator","denotations":[{"id":"69","span":{"begin":136,"end":144},"obj":"Species"},{"id":"70","span":{"begin":241,"end":252},"obj":"Species"},{"id":"71","span":{"begin":283,"end":292},"obj":"Species"},{"id":"72","span":{"begin":297,"end":301},"obj":"Species"},{"id":"73","span":{"begin":330,"end":340},"obj":"Species"}],"attributes":[{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"Tax:694009"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"Tax:11118"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"Tax:11137"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"Tax:11149"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}

{"project":"2_test","denotations":[{"id":"33054210-12917450-61913442","span":{"begin":130,"end":131},"obj":"12917450"}],"text":"The function of this internally encoded 3CLpro is integral to the processing of these proteins and critical for viral replication.7 The SARS CoV-1 3CLpro shares a high degree of structural homology and similar substrate specificity with the coronavirus 3C-like cysteine proteases of hCoV 229E and TGEV8 but is most similar to the SARS CoV-2 3CLpro."}